Abstract：
:Congenital abnormalities, cancer, trauma, infection, inflammation, iatrogenic injuries, and other conditions may lead to genitourinary organ damage or loss, requiring eventual reconstruction. Tissue engineering follows the principles of cell transplantation, materials science, and engineering toward the development of biological substitutes that would restore and maintain normal function. Tissue engineering may involve matrices alone, wherein the body's natural ability to regenerate is used to orient or direct new tissue growth, or the use of matrices with cells. Both synthetic (polyglycolic acid polymer scaffolds alone and with co-polymers of poly-1-lactic acid and poly-DL-lactide-coglycolide) and natural biodegradable materials (processed collagen derived from allogeneic donor bladder submucosa and intestinal submucosa) have been used, either alone or as cell delivery vehicles. Tissue engineering has been applied experimentally for the reconstitution of several urologic tissues and organs, including bladder, ureter, urethra, kidney, testis, and genitalia. Fetal applications have also been explored. Recently, several tissue engineering technologies have been used clinically, including the use of cells as bulking agents for the treatment of vesicoureteral reflux and incontinence, urethral replacement, and bladder reconstruction. Recent progress suggests that engineered urologic tissues may have clinical applicability in the future.
journal_name
Curr Urol Repjournal_title
Current urology reportsauthors
Atala Adoi
10.1007/s11934-001-0030-zkeywords:
subject
Has Abstractpub_date
2001-02-01 00:00:00pages
83-92issue
1eissn
1527-2737issn
1534-6285journal_volume
2pub_type
杂志文章,评审abstract：:Laparoscopic adrenalectomy is considered to be the standard of care for the surgical excision of the adrenal gland. Since the initial report of laparoscopic adrenalectomy in 1992, it has evolved into a feasible and reproducible minimally invasive procedure for benign adrenal tumors. Transperitoneal and retroperitoneal...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-005-0070-x
更新日期：2005-02-01 00:00:00
abstract：:The benefit that patients with overactive bladder (OAB) experience with conservative management is an important aspect in the evaluation of this therapy. The first-line options include behavioral interventions, and several techniques are available. Clinical research indicates amelioration of individual symptoms with t...
journal_title：Current urology reports
pub_type： 杂志文章
doi：10.1007/s11934-012-0262-0
更新日期：2012-10-01 00:00:00
abstract：PURPOSE OF REVIEW:While recurrence after primary treatment of prostate cancer (PCa) is not uncommon, there is currently no consensus on the most appropriate management after radiation treatment failure. This article seeks to explore the currently utilized modalities for salvage treatment for radiorecurrent PCa. We focu...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-017-0709-4
更新日期：2017-08-01 00:00:00
abstract：:Non-muscle-invasive bladder cancer is characterized by frequent recurrences requiring repeated transurethral resections and carries a risk of progression to muscle-invasive disease. The routinely used, passive diffusion irrigation of the bladder with mitomycin C has achieved limited success in avoiding these events. W...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-012-0302-9
更新日期：2013-04-01 00:00:00
abstract：:Nodal staging is important in prostate cancer treatment. While surgical lymph node dissection is the classic method of determining whether lymph nodes harbor malignancy, this is a very invasive technique. Current noninvasive approaches to identifying malignant lymph nodes are limited. Conventional imaging methods rely...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-015-0505-y
更新日期：2015-05-01 00:00:00
abstract：PURPOSE OF REVIEW:Bladder cancer care is costly due to long surveillance periods for non-muscle-invasive bladder cancer (NMIBC) and comorbidities associated with the surgical treatment of muscle-invasive bladder cancer (MIBC). We reviewed current evidence-based practices and propose quality metrics for NMIBC and MIBC. ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-018-0856-2
更新日期：2018-10-24 00:00:00
abstract：:Despite the proven efficacy of oral therapy for erectile dysfunction (ED), some patients are unable to take these medications because of drug interactions (ie, sildenafil and nitroglycerin) or a lack of response. Topical agents represent another minimally invasive option for the treatment of ED. This review discusses ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-002-0100-x
更新日期：2002-12-01 00:00:00
abstract：:Chronic nonbacterial prostatitis, or urological chronic pelvic pain syndrome (UCPPS), remains a common and often challenging disorder to evaluate and treat. Employing a more holistic approach, including urological therapy, physical therapy, and psychosocial perspectives, may be more appropriate for most patients. Grow...
journal_title：Current urology reports
pub_type： 杂志文章
doi：10.1007/s11934-009-0047-2
更新日期：2009-07-01 00:00:00
abstract：:Adrenal hemorrhage is a rare yet potentially life-threatening event that occurs both in traumatic conditions and in a variety of nontraumatic conditions. Clinical manifestations of adrenal hemorrhage can vary widely depending on the degree and rate of hemorrhage, as well as the amount of adrenal cortex compromised by ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-009-0014-y
更新日期：2009-01-01 00:00:00
abstract：PURPOSE OF REVIEW:To discuss considerations and current evidence for the diagnosis and management of vaginal mesh exposures following female mesh-augmented anti-incontinence and pelvic organ prolapse surgery. RECENT FINDINGS:Since the introduction of mesh into female pelvic surgery, various applications have been repo...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-020-01002-0
更新日期：2020-10-30 00:00:00
abstract：:Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is the most common category of clinical prostatitis. The etiologic factors of CP/CPPS still remain unknown, and standard therapies often fail to achieve sustainable amelioration of symptoms; therefore, various treatment therapies have been approached. Recently...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-011-0186-0
更新日期：2011-08-01 00:00:00
abstract：:Testosterone (T) deficiency syndrome (TDS) is a prevalent condition, commonly managed with exogenous T. Despite an abundance of T formulations, alternative treatments are often sought for various reasons. To evaluate outcomes of alternative therapies, a PubMed search was performed of all publications that included men...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-014-0417-2
更新日期：2014-07-01 00:00:00
abstract：:Most adrenal tumors are found incidentally and appear as small solitary nodules on abdominal imaging. Occasionally, work-up demonstrates multifocal or bilateral adrenal tumors. Certain patients are predisposed to multiple lesions, such as those with hereditary forms of pheochromocytoma as seen in von Hippel-Lindau dis...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-001-0021-0
更新日期：2001-02-01 00:00:00
abstract：:Neoadjuvant cisplatin-based combination chemotherapy is an established standard for resectable muscle-invasive bladder cancer, a disease with a pattern of predominantly distant and early recurrences. Pathologic complete remission appears to be an intermediate surrogate for survival when employing combination chemother...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-012-0236-2
更新日期：2012-04-01 00:00:00
abstract：:The presence of a sufficient amount of androgens is essential for adequate sexual function in men. Gonadal hormones profoundly affect cognitive functions and, therefore, are fundamental in maintaining sexual desire. The earliest manifestation of hypogonadism is diminished libido. Furthermore, androgens also act periph...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-011-0202-4
更新日期：2011-12-01 00:00:00
abstract：:Urgency and urinary urge incontinence are troublesome and complex symptoms that can complicate the diagnosis and treatment of stress urinary incontinence. Despite this fact, first-line intervention frequently is directed toward the incompetent bladder neck using surgical approaches. Persistent urgency or detrusor inst...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-004-0065-z
更新日期：2004-12-01 00:00:00
abstract：:Partial nephrectomy has become an accepted treatment of cT1 renal masses as it provides improved long-term renal function compared to radical nephrectomy (Campbell et al. J Urol. 182:1271-9, 2009). Hilar clamping is utilized to help reduce bleeding and improve visibility during tumor resection. However, concern over r...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-016-0596-0
更新日期：2016-05-01 00:00:00
abstract：PURPOSE OF REVIEW:The symptoms of lower urinary tract dysfunction (LUTD) including urinary incontinence, frequency, and urgency are among the most common reasons children are referred to pediatric urologists. Despite this, the workup for LUTD is often time consuming and a source of frustration for patients, parents, an...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-018-0784-1
更新日期：2018-04-06 00:00:00
abstract：:The inability of urologists to consistently and effectively treat men with chronic pelvic pain syndrome (CPPS), also known as chronic abacterial prostatitis, is a source of great frustration. Botulinum toxin (BTX), a potent neurotoxin, can act on most of the peripheral nerves of the pelvis through a variety of mechani...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-010-0118-4
更新日期：2010-07-01 00:00:00
abstract：:DNA microarray technology provides a means to examine large numbers of molecular changes related to a biological process in a high throughput manner. This review discusses plausible utilities of this technology in prostate cancer research, including definition of prostate cancer predisposition, global profiling of gen...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-002-0011-x
更新日期：2002-02-01 00:00:00
abstract：:Robot-assisted surgery has changed the landscape of surgery. Implementation of robotics into most surgical specialties has left many educators challenged to develop the tools necessary to train and credential surgeons. Advances in robot-assisted surgery have led to the development of simulators and tools to assess ski...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-015-0508-8
更新日期：2015-06-01 00:00:00
abstract：:Patients diagnosed with prostate cancer who elect to pursue active treatment of their disease must choose among the many available treatment alternatives. Several treatment options now exist for similar-stage disease (clinical T1-3N0M0), including radical prostatectomy, external beam radiation, prostate brachytherapy ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-000-0034-0
更新日期：2000-05-01 00:00:00
abstract：PURPOSE OF REVIEW:Urethral strictures that are refractory to initial management present unique challenges to the reconstructive surgeon. Treatment trends have shifted as new tissue resources are becoming available. There is renewed interest in old methods as skill and technique have improved. We describe the scope of t...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-018-0769-0
更新日期：2018-02-26 00:00:00
abstract：PURPOSE OF THE REVIEW:To update the most relevant literature regarding complex vascular cases in kidney transplant setting involving the graft, especially during the harvesting procedure and back-table preparation from the subsequent implant. RECENT FINDINGS:Challenging situations affecting the kidney graft such as mu...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-020-0955-8
更新日期：2020-01-31 00:00:00
abstract：BACKGROUND:Vesico-vaginal fistulae (VVF) remain the most prevalent genitourinary fistula detrimentally impacting quality of life. PURPOSE OF THE REVIEW:The purpose of this review is to examine relevant literature on management of VVF. RECENT FINDINGS:Obstructed labor is the leading cause of VVF in the developing worl...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-017-0708-5
更新日期：2017-08-01 00:00:00
abstract：:Overactive bladder syndrome continues to be a significant burden for the general population. Current first-line medical therapy often includes antimuscarinic medications designed for overactive bladder. Poor efficacy and significant side effects of these antimuscarinic medications have left patients and physicians loo...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-010-0134-4
更新日期：2010-09-01 00:00:00
abstract：:Within the past 25 years, lasers have transitioned from merely destructive or ablative tools to those with reconstructive uses. It has been shown that the application of laser thermal energy to tissue will result in welding of the approximated areas. Furthermore, the addition of protein solder and chromophores (tissue...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-003-0058-3
更新日期：2003-02-01 00:00:00
abstract：PURPOSE OF REVIEW:Amid the opioid crisis, postoperative pain management is a major challenge for practitioners. Recent pain management guidelines emphasize the importance of using regional anesthesia as part of opioid-sparing multimodal analgesia. This report aims to review recent evidence regarding the utilization of ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-019-0883-7
更新日期：2019-03-23 00:00:00
abstract：:Benign prostatic hyperplasia (BPH) is one of the most common causes of lower urinary tract symptoms (LUTS) in aging men. Over the age of 60, more than a half of men have BPH and/or bothersome LUTS. Contemporary guidelines advocate surgery as the standard of care for symptomatic BPH after failure of medical therapy, wh...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-016-0601-7
更新日期：2016-06-01 00:00:00
abstract：PURPOSE OF REVIEW:Patient-reported outcome measures (PROMs) are tools that are widely used by clinicians and researchers across different medical specialties. In this review, we examine the use of PROMs in the evaluation of female pelvic floor disorders (PFD). RECENT FINDINGS:PROM development in the assessment of urin...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-019-0888-2
更新日期：2019-03-27 00:00:00
