Abstract：
:Despite the proven efficacy of oral therapy for erectile dysfunction (ED), some patients are unable to take these medications because of drug interactions (ie, sildenafil and nitroglycerin) or a lack of response. Topical agents represent another minimally invasive option for the treatment of ED. This review discusses the impediments to effective topical therapy and examines the developmental status of several candidate drugs. Although still in the investigative stage, topical medications can be another tool in the urologist's armamentarium against ED.
journal_name
Curr Urol Repjournal_title
Current urology reportsauthors
Yap RL,McVary KTdoi
10.1007/s11934-002-0100-xkeywords:
subject
Has Abstractpub_date
2002-12-01 00:00:00pages
471-6issue
6eissn
1527-2737issn
1534-6285journal_volume
3pub_type
杂志文章,评审abstract：:To decrease side effects observed after high-intensity focused ultrasound (HIFU) treatment for localized prostate cancer and to re-establish normal micturition in a patient population that often presents with concomitant prostate enlargement, the impact of a combined transurethral resection of the prostate (TURP) and ...
journal_title：Current urology reports
pub_type： 临床试验,杂志文章
doi：10.1007/s11934-003-0077-0
更新日期：2003-06-01 00:00:00
abstract：:Adolescents with varicoceles represent a large and heterogeneous group. This patient population has rapidly changing hormonal levels and may present at different stages of physical and pubertal development. At the same time, the adolescent varicocele is becoming a more widely appreciated and diagnosed entity with an e...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-009-0026-7
更新日期：2009-03-01 00:00:00
abstract：:This article reviews the mechanisms by which vaginal surgery affects female sexual function and related pathophysiology to potential causes. The anatomy, neurovascular supply of the clitoris and introitus, and intrapelvic nerve supply are discussed as they apply to vaginal surgery. Methods to avoid neurovascular damag...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-004-0091-x
更新日期：2004-10-01 00:00:00
abstract：:Laparoscopic partial nephrectomy (LPN) was first described in 1992. Its increased use in recent years is a product of overall trends in surgery to minimize operative morbidity, as well as the downward stage migration of renal tumors detected incidentally through widespread medical imaging. Today the indications for LP...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-009-0083-y
更新日期：2010-02-01 00:00:00
abstract：PURPOSE OF REVIEW:Spina bifida is caused by incomplete neural tube closure during the first trimester. This condition may lead to bowel and bladder dysfunction as well as truncal weakness and motor anomalies. Presentations vary between myelomeningoceles and lipomeningoceles and may result in different outcomes. This re...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-017-0684-9
更新日期：2017-05-01 00:00:00
abstract：:DNA microarray technology provides a means to examine large numbers of molecular changes related to a biological process in a high throughput manner. This review discusses plausible utilities of this technology in prostate cancer research, including definition of prostate cancer predisposition, global profiling of gen...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-002-0011-x
更新日期：2002-02-01 00:00:00
abstract：:The use of injectable bulking agents into the submucosal layer of the pediatric urinary tract continues to grow. Treatment strategies for vesicoureteral reflux and urinary incontinence have changed with the introduction of dextranomer/hyaluronic acid as a minimally invasive option. Socially and medically debilitating ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-006-0074-1
更新日期：2006-03-01 00:00:00
abstract：:Laparoscopic surgery was originally developed by gynecologists and general surgeons. Based on their experience, the first successful laparoscopic procedures in urology were performed transperitoneally. However, this novel technique transformed traditionally retroperitoneal procedures into transperitoneal procedures, g...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-004-0020-z
更新日期：2004-04-01 00:00:00
abstract：PURPOSE OF REVIEW:This review provides a critical literature overview of the risks and benefits of transplantectomy in patients with a failed allograft. Additionally, it offers a summary of related problems, primarily alloantibody sensitization in the event of nephrectomy and immunosuppression weaning. RECENT FINDINGS...
journal_title：Current urology reports
pub_type： 杂志文章
doi：10.1007/s11934-020-0957-6
更新日期：2020-01-18 00:00:00
abstract：PURPOSE OF REVIEW:Molecular characterization of cancer allows us to understand oncogenesis and clinical prognosis as well as facilitates development of biomarkers and treatment. Our aim was to review the current literature on genomic characterization of bladder cancer, and how far we are in implementing genomics into c...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-020-0960-y
更新日期：2020-03-13 00:00:00
abstract：:Approximately one in seven American men will be diagnosed with prostate cancer during his lifetime, and at least 50% of newly diagnosed patients will present with low-risk disease. In the last decade, the decision-making paradigm for management has shifted due to high rates of disease detection and overtreatment, attr...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-015-0507-9
更新日期：2015-06-01 00:00:00
abstract：:The presence of a sufficient amount of androgens is essential for adequate sexual function in men. Gonadal hormones profoundly affect cognitive functions and, therefore, are fundamental in maintaining sexual desire. The earliest manifestation of hypogonadism is diminished libido. Furthermore, androgens also act periph...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-011-0202-4
更新日期：2011-12-01 00:00:00
abstract：PURPOSE OF REVIEW:Recurrent urinary tract infections are a common condition that can impact patients' quality of life. The purpose of this review is to summarize and analyze the literature regarding the distress that these infections can cause to patients and provide guidance to clinicians on how to improve care of the...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-018-0849-1
更新日期：2018-10-18 00:00:00
abstract：:Medical treatments for lower urinary tract symptoms due to benign prostatic hyperplasia are frequently associated with changes in sexual function. While these medications are generally well-tolerated and have both reduced and delayed more invasive surgical options, the ramifications of long-term chronic use are largel...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-014-0441-2
更新日期：2014-10-01 00:00:00
abstract：:For many years, estrogen has been used to treat lower urinary tract dysfunction in postmenopausal women. The data supporting this practice vary. Large multi-institutional studies have shown little role for systemic estrogens in the treatment of urinary incontinence. Vaginal estrogen preparations show superiority to sy...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-011-0208-y
更新日期：2011-10-01 00:00:00
abstract：:There is substantial variability in the extent of the node dissection performed during radical cystectomy for bladder cancer. Here, we review the diagnostic assessment of lymph node metastasis and the prognostic and therapeutic benefit for pelvic node dissection for bladder cancer. A review of the applicable urologic ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-012-0235-3
更新日期：2012-04-01 00:00:00
abstract：:Adrenal cortical carcinoma is a relatively uncommon malignancy that represents a significant clinical challenge for the development of optimal treatment strategies. Historically, successful treatment has relied upon rapid identification of the lesion, accurate staging with diagnostic imaging, and complete surgical ext...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-007-0024-6
更新日期：2007-01-01 00:00:00
abstract：:Tuberculosis of the genitourinary tract presents with atypical manifestations. Only 20% to 30% of patients with genitourinary tuberculosis have a history of pulmonary infection. Tuberculosis often affects the lower genitourinary system rather than the kidney. Tuberculosis of the lower genitourinary tract most commonly...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-008-0053-9
更新日期：2008-07-01 00:00:00
abstract：:Inflatable penile prosthesis (IPP) is an effective treatment for erectile dysfunction in patients' refractory to oral or injectable treatment. While the rate of infection has decreased over the past decade, it is still the most feared complication of IPP placement. Here, we assemble possible patient and surgical facto...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-015-0554-2
更新日期：2015-12-01 00:00:00
abstract：:Global improvements in water quality, management of infectious diseases, and other medical therapeutics have resulted in a growing population of healthy aging men. One obligate anatomic consequence of aging for these men is the development of benign prostatic hyperplasia (BPH) with secondary bladder outlet obstruction...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-014-0403-8
更新日期：2014-05-01 00:00:00
abstract：:Benign prostatic hyperplasia (BPH) is a common cause of lower urinary tract symptoms (LUTS) in men. Patients with BPH often present with a combination of obstructive and overactive bladder (OAB) symptoms. It is postulated that bladder outlet obstruction (BOO) from BPH results in concomitant OAB symptoms through ischem...
journal_title：Current urology reports
pub_type： 杂志文章
doi：10.1007/s11934-013-0363-4
更新日期：2013-12-01 00:00:00
abstract：PURPOSE OF REVIEW:Although benign, renal angiomyolipoma (AML) may lead to serious complications without appropriate management. The purpose of this review is to describe the role of and evidence for interventional radiology techniques in the management of patients with AML. RECENT FINDINGS:For patients with renal mass...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-017-0687-6
更新日期：2017-05-01 00:00:00
abstract：PURPOSE OF REVIEW:For many diseases that place a large burden on our health care system, men often have worse health outcomes than women. As the largest single provider of health care to men in the USA, the Veterans Health Administration (VA) has the potential to serve as leader in the delivery of improved men's health...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-017-0733-4
更新日期：2017-09-18 00:00:00
abstract：:The cholinergic system of the bladder includes muscarinic receptors distributed to detrusor myocytes and structures within mucosa including bladder afferent (sensory) nerves. The receptors have been shown to be involved in afferent signaling from the bladder, but it has not been established to what extent effects on t...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-008-0079-z
更新日期：2008-11-01 00:00:00
abstract：:Patients with one or more low-grade bladder tumors of the urinary bladder will often develop a subsequent tumor but these so called "recurrences" are almost always of similar grade and rarely invade beyond the basement membrane. Therefore, the clinician should try to minimize the morbidity associated with treating the...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-015-0555-1
更新日期：2015-12-01 00:00:00
abstract：:Peyronie's disease (PD) is the occurrence of a fibrous inelastic scar of the tunica albuginea of the penis. It is a relatively common disorder among men, with a reported prevalence of 3% to 8%. It is often associated with penile pain, anatomical deformities in the erect state, and difficulty with intromission. Because...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-011-0212-2
更新日期：2011-12-01 00:00:00
abstract：:The development of a lymphocele after pelvic surgery is a well-documented complication, especially where pelvic lymph node dissection (PLND) is part of the operation. However, not all lymphoceles are symptomatic and require treatment. Most lymphoceles spontaneously resolve, and even lymphoceles that become symptomatic...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-014-0445-y
更新日期：2014-10-01 00:00:00
abstract：PURPOSE OF REVIEW:We sought to determine whether infertile men can accurately be identified within a large insurance claims database to validate its use for reproductive health research. RECENT FINDINGS:Prior literature suggests that men coded for infertility are at higher risk for chronic disease though it was previo...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-017-0714-7
更新日期：2017-09-01 00:00:00
abstract：:Numerous surgeries have been proposed for the treatment of genuine stress incontinence, with the goals to improve functional outcome and decrease complications and their associated morbidity. Two new, minimally invasive procedures, transvaginal retropubic urethropexy and transvaginal Cooper's ligament sling, are revie...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-996-0018-9
更新日期：2001-10-01 00:00:00
abstract：:Preservation of postoperative urinary continence remains the primary concern of all men and their surgeons following robot-assisted radical prostatectomy (RARP). Without doubt, continence is the most important quality of life issue following radical prostatectomy. Identification of difficulties and lessons learned ove...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-012-0295-4
更新日期：2013-02-01 00:00:00
