Abstract:
:For many years, estrogen has been used to treat lower urinary tract dysfunction in postmenopausal women. The data supporting this practice vary. Large multi-institutional studies have shown little role for systemic estrogens in the treatment of urinary incontinence. Vaginal estrogen preparations show superiority to systemic estrogens for the treatment of irritative voiding symptoms in meta-analysis, but there is significant study heterogeneity and the practice remains debatable. Data from randomized controlled trials support estrogen use in the prevention of recurrent urinary tract infections. This article reviews the relevant literature addressing the role of estrogen therapy in urinary incontinence, irritative voiding symptoms, and recurrent urinary tract infections.
journal_name
Curr Urol Repjournal_title
Current urology reportsauthors
Koski ME,Chermansky CJdoi
10.1007/s11934-011-0208-ysubject
Has Abstractpub_date
2011-10-01 00:00:00pages
345-50issue
5eissn
1527-2737issn
1534-6285journal_volume
12pub_type
杂志文章,评审abstract:PURPOSE OF THE REVIEW:This review targets the latest literature on bladder preservation therapy with emphasis on trimodal therapy (TMT), highlighting its role in the management of muscle invasive bladder cancer (MIBC) and outlining future directions in bladder preservation research. RECENT FINDINGS:TMT is the most pro...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-018-0859-z
更新日期:2018-11-03 00:00:00
abstract::Correct staging of prostate cancer at initial diagnosis, as well as accurate staging and tumor localization with biochemical recurrence, remains generally inaccurate with current imaging techniques. Newer modalities are being investigated to accurately identify patients with prostate cancer at different stages of dise...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-006-0018-9
更新日期:2006-05-01 00:00:00
abstract::Androgen deprivation therapy (ADT) is a well-established treatment for locally advanced, biochemically recurrent and metastatic prostate cancer. However, it is associated with significant side effects including hot flashes, loss of libido and erectile function, muscular atrophy, metabolic abnormalities, and osteoporos...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-015-0481-2
更新日期:2015-03-01 00:00:00
abstract::Approximately one in seven American men will be diagnosed with prostate cancer during his lifetime, and at least 50% of newly diagnosed patients will present with low-risk disease. In the last decade, the decision-making paradigm for management has shifted due to high rates of disease detection and overtreatment, attr...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-015-0507-9
更新日期:2015-06-01 00:00:00
abstract::Benign prostatic hyperplasia (BPH) is a common cause of lower urinary tract symptoms (LUTS) in men. Patients with BPH often present with a combination of obstructive and overactive bladder (OAB) symptoms. It is postulated that bladder outlet obstruction (BOO) from BPH results in concomitant OAB symptoms through ischem...
journal_title:Current urology reports
pub_type: 杂志文章
doi:10.1007/s11934-013-0363-4
更新日期:2013-12-01 00:00:00
abstract::At present, it is reasonable to counsel all patients, as well as family members of patients, who have a palpable varicocele about the long-term risks for impaired fertility. Currently, no one can predict with absolute certainty if any adolescent with a varicocele will be at risk for future infertility. Based on existi...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-002-0019-2
更新日期:2002-04-01 00:00:00
abstract::Most children born with spina bifida, the most common disabling congenital abnormality, have normal renal function. If left untreated, more than half of these children will have serious renal deterioration by age 5. This deterioration is secondary to hostile neurogenic changes of the bladder. Renal development should ...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-008-0027-y
更新日期:2008-03-01 00:00:00
abstract::DNA microarray technology provides a means to examine large numbers of molecular changes related to a biological process in a high throughput manner. This review discusses plausible utilities of this technology in prostate cancer research, including definition of prostate cancer predisposition, global profiling of gen...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-002-0011-x
更新日期:2002-02-01 00:00:00
abstract::Congenital abnormalities, cancer, trauma, infection, inflammation, iatrogenic injuries, and other conditions may lead to genitourinary organ damage or loss, requiring eventual reconstruction. Tissue engineering follows the principles of cell transplantation, materials science, and engineering toward the development of...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-001-0030-z
更新日期:2001-02-01 00:00:00
abstract::Phthalates are part of a class of high-volume industrial chemicals used ubiquitously in health care as well as household products. Biomarker studies have confirmed the widespread presence of these chemicals in both humans and animals. As a class, phthalates have been implicated in diseases and birth anomalies of the g...
journal_title:Current urology reports
pub_type: 杂志文章
doi:10.1007/s11934-012-0261-1
更新日期:2012-08-01 00:00:00
abstract::Peyronie's disease (PD) is the occurrence of a fibrous inelastic scar of the tunica albuginea of the penis. It is a relatively common disorder among men, with a reported prevalence of 3% to 8%. It is often associated with penile pain, anatomical deformities in the erect state, and difficulty with intromission. Because...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-011-0212-2
更新日期:2011-12-01 00:00:00
abstract:PURPOSE OF REVIEW:The goal of this paper is to describe the pathophysiology of adult nocturnal enuresis and develop a generalized approach for evaluation and treatment. RECENT FINDINGS:Although nocturnal enuresis (NE) impacts a significant proportion of the adult population, research on this topic remains lacking. In ...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-020-00983-2
更新日期:2020-06-06 00:00:00
abstract:PURPOSE OF REVIEW:The clinical role of fluorine-18 fluoro-2-deoxyglucose (FDG)-positron emission tomography (PET) in renal cell carcinoma (RCC) is still evolving. Use of FDG PET in RCC is currently not a standard investigation in the diagnosis and staging of RCC due to its renal excretion. This review focuses on the cl...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-019-0932-2
更新日期:2019-08-29 00:00:00
abstract::The development of a lymphocele after pelvic surgery is a well-documented complication, especially where pelvic lymph node dissection (PLND) is part of the operation. However, not all lymphoceles are symptomatic and require treatment. Most lymphoceles spontaneously resolve, and even lymphoceles that become symptomatic...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-014-0445-y
更新日期:2014-10-01 00:00:00
abstract::The objective of this review is to discuss the main goals of pelvic organ prolapse repair. Pelvic organ prolapse symptoms are variable, and prolapse degree does not necessarily correlate with perceived symptoms or other associated conditions including urinary, defecatory, and sexual dysfunction. Treatment for pelvic o...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-013-0385-y
更新日期:2014-02-01 00:00:00
abstract::Robot-assisted surgery has become a widely used surgical approach in the management of urologic malignancies. With its initial experience in the treatment of prostate cancer, the technology rapidly expanded to other urologic malignancies including bladder cancer. Since its introduction in 2003, robot-assisted radical ...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-016-0598-y
更新日期:2016-06-01 00:00:00
abstract:PURPOSE OF REVIEW:Molecular characterization of cancer allows us to understand oncogenesis and clinical prognosis as well as facilitates development of biomarkers and treatment. Our aim was to review the current literature on genomic characterization of bladder cancer, and how far we are in implementing genomics into c...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-020-0960-y
更新日期:2020-03-13 00:00:00
abstract:PURPOSE OF REVIEW:Targeting PD-1/PD-L1 immune checkpoints is a new therapeutic tool in patients with locally advanced and metastatic clear cell renal cell carcinoma (CCRCC). The purpose of this review is to offer clinicians an updated translational insight into the current status of a therapeutic alternative that may i...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-019-0866-8
更新日期:2019-01-15 00:00:00
abstract::For patients with muscle-invasive bladder cancer, the decision to undergo radical cystectomy or bladder preservation treatment must incorporate survival differences, toxicity, and quality of life. Our objective was to review patient-reported outcomes for bladder preservation treatment with a focus on patients eligible...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-015-0547-1
更新日期:2015-11-01 00:00:00
abstract::The inability of urologists to consistently and effectively treat men with chronic pelvic pain syndrome (CPPS), also known as chronic abacterial prostatitis, is a source of great frustration. Botulinum toxin (BTX), a potent neurotoxin, can act on most of the peripheral nerves of the pelvis through a variety of mechani...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-010-0118-4
更新日期:2010-07-01 00:00:00
abstract::Urgency and urinary urge incontinence are troublesome and complex symptoms that can complicate the diagnosis and treatment of stress urinary incontinence. Despite this fact, first-line intervention frequently is directed toward the incompetent bladder neck using surgical approaches. Persistent urgency or detrusor inst...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-004-0065-z
更新日期:2004-12-01 00:00:00
abstract:PURPOSE OF REVIEW:There are an estimated 33 million men and women with overactive bladder (OAB) in the USA. Despite the prevalence of OAB, it remains a frequently misdiagnosed condition. OAB has shared symptomatology with other common urologic conditions, namely recurrent urinary tract infections (UTIs). Here, we will ...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-018-0839-3
更新日期:2018-09-13 00:00:00
abstract::The prostate-specific antigen (PSA) era has increased the rates of prostate cancer detection and treatment, while reducing the risk of death from prostate cancer in the US. Image-guided prostate biopsy techniques have led to stage migration and the detection and treatment of lower risk prostate cancers. Improved techn...
journal_title:Current urology reports
pub_type: 杂志文章
doi:10.1007/s11934-012-0285-6
更新日期:2012-12-01 00:00:00
abstract:PURPOSE OF REVIEW:Recurrent urinary tract infections are a common condition that can impact patients' quality of life. The purpose of this review is to summarize and analyze the literature regarding the distress that these infections can cause to patients and provide guidance to clinicians on how to improve care of the...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-018-0849-1
更新日期:2018-10-18 00:00:00
abstract::Erectile dysfunction (ED) is common after radical prostatectomy (RP). ED has a negative impact on health-related quality of life. Penile rehabilitation is defined as the use of any drug or device at or after RP to maximize erectile function recovery. The purpose of penile rehabilitation is the prevention of corpus cav...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-009-0037-4
更新日期:2009-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Urethral reconstruction has evolved in the last several decades with the introduction of various techniques including fasciocutaneous skin flaps and buccal mucosal grafts. However, distal urethral strictures have continued to be a reconstructive challenge due to tendency for adverse cosmetic outcomes,...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-018-0792-1
更新日期:2018-04-17 00:00:00
abstract::Recent studies have cast doubt on the reliability of serum total prostate-specific antigen as a biomarker for the detection and prognosis of prostate cancer. Biomarkers that can identify those men at risk for clinically significant prostate cancer are desperately needed. The search for biomarkers that may improve the ...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-005-0004-7
更新日期:2005-05-01 00:00:00
abstract:PURPOSE OF REVIEW:While recurrence after primary treatment of prostate cancer (PCa) is not uncommon, there is currently no consensus on the most appropriate management after radiation treatment failure. This article seeks to explore the currently utilized modalities for salvage treatment for radiorecurrent PCa. We focu...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-017-0709-4
更新日期:2017-08-01 00:00:00
abstract:PURPOSE OF REVIEW:To discuss considerations and current evidence for the diagnosis and management of vaginal mesh exposures following female mesh-augmented anti-incontinence and pelvic organ prolapse surgery. RECENT FINDINGS:Since the introduction of mesh into female pelvic surgery, various applications have been repo...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-020-01002-0
更新日期:2020-10-30 00:00:00
abstract:PURPOSE OF REVIEW:The goal of this paper was to review the novel treatment modality of high-intensity transurethral directional ultrasound for prostate cancer. RECENT FINDINGS:Prostate cancer is a heterogeneous disease with some patients electing for active surveillance and focal therapies instead of definitive treatm...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-020-01020-y
更新日期:2021-01-06 00:00:00