Abstract：
:For patients with muscle-invasive bladder cancer, the decision to undergo radical cystectomy or bladder preservation treatment must incorporate survival differences, toxicity, and quality of life. Our objective was to review patient-reported outcomes for bladder preservation treatment with a focus on patients eligible for radical cystectomy, for whom a comparison of patient-reported outcomes is most relevant. Peer-reviewed, English-language manuscripts in MEDLINE and PubMed databases were examined from 1996 through 2014. Subject headings included quality of life, bladder cancer, bladder sparing, bladder preservation, radiation, and radiotherapy. Prospective and retrospective studies of patient-reported outcomes in patients undergoing bladder preservation with radiotherapy for muscle-invasive bladder cancer were included. Two prospective studies and four retrospective studies were identified. Several weaknesses from these studies were identified including small sample sizes, variable time points of assessment, variation in treatment regimens, and failure to use validated or condition-specific questionnaires. From the available data, bladder preservation appears to result to similar or better general quality of life compared to radical cystectomy with satisfactory urinary and sexual function reported in most series. In general, bladder preservation resulted in more gastrointestinal symptoms than radical cystectomy. This is one of the first reviews on the subject of patient-reported outcomes for bladder preservation in muscle-invasive bladder cancer. Although the data are limited, this review may provide a framework for developing well-designed, prospective comparisons of treatment for this patient cohort.
journal_name
Curr Urol Repjournal_title
Current urology reportsauthors
Feuerstein MA,Goenka Adoi
10.1007/s11934-015-0547-1subject
Has Abstractpub_date
2015-11-01 00:00:00pages
75issue
11eissn
1527-2737issn
1534-6285journal_volume
16pub_type
杂志文章,评审abstract：:Most children born with spina bifida, the most common disabling congenital abnormality, have normal renal function. If left untreated, more than half of these children will have serious renal deterioration by age 5. This deterioration is secondary to hostile neurogenic changes of the bladder. Renal development should ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-008-0027-y
更新日期：2008-03-01 00:00:00
abstract：:Each of the three most common contemporary treatments for localized prostate cancer, radical prostatectomy, external beam radiotherapy, and brachytherapy, can have adverse effects on sexual health. Sexual health outcome can be improved by treatment-specific factors, such as the use of nerve-sparing technique during ra...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-004-0039-1
更新日期：2004-06-01 00:00:00
abstract：:Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is the most common category of clinical prostatitis. The etiologic factors of CP/CPPS still remain unknown, and standard therapies often fail to achieve sustainable amelioration of symptoms; therefore, various treatment therapies have been approached. Recently...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-011-0186-0
更新日期：2011-08-01 00:00:00
abstract：PURPOSE OF REVIEW:Inflatable penile prosthesis (IPP) is a treatment for erectile dysfunction. IPPs have undergone improvements; however, post-surgical infections still occur. Furthermore, the type of pathogens infecting the implants has changed recently from Gram-positive to Gram-negative bacteria and fungi due to adva...
journal_title：Current urology reports
pub_type： 历史文章,杂志文章,评审
doi：10.1007/s11934-019-0874-8
更新日期：2019-01-30 00:00:00
abstract：:Complications of locally advanced prostate cancer are often overlooked in the overall treatment of prostate cancer, can have significant morbidity, and can provide a challenge for the treating urologist. Despite advances in early detection and treatment of prostate cancer, as many as 10% of patients present with or de...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-007-0008-6
更新日期：2007-05-01 00:00:00
abstract：:Complementary and alternative medicine (CAM) has recently attracted national attention in the United States because of its widespread use and associated cost. CAM covers a broad spectrum of healing philosophies and approaches. Despite its widespread use, little is known about its safety, efficacy, cost effectiveness, ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-001-0084-y
更新日期：2001-06-01 00:00:00
abstract：:The cholinergic system of the bladder includes muscarinic receptors distributed to detrusor myocytes and structures within mucosa including bladder afferent (sensory) nerves. The receptors have been shown to be involved in afferent signaling from the bladder, but it has not been established to what extent effects on t...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-008-0079-z
更新日期：2008-11-01 00:00:00
abstract：PURPOSE OF REVIEW:This article explores the anatomy, management options, and outcomes of pelvic organ prolapse with a female cystectomy patient. RECENT FINDINGS:There is a lack of data on surgical management outcomes for prolapse following radical cystectomy. However, most case series from tertiary referral centers sh...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-019-0941-1
更新日期：2019-10-15 00:00:00
abstract：:Adolescents with varicoceles represent a large and heterogeneous group. This patient population has rapidly changing hormonal levels and may present at different stages of physical and pubertal development. At the same time, the adolescent varicocele is becoming a more widely appreciated and diagnosed entity with an e...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-009-0026-7
更新日期：2009-03-01 00:00:00
abstract：:Erectile dysfunction (ED) often is caused by endothelial dysfunction and may be a sign that a patient has vascular disease elsewhere in the body. Risk factors for coronary artery disease such as lipid abnormalities, smoking, diabetes, and hypertension also are risk factors for ED. Oral therapy for ED, such as sildenaf...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-003-0028-9
更新日期：2003-12-01 00:00:00
abstract：:Lipoxygenases oxidatively metabolize polyunsaturated fatty acids to a rich spectrum of biologically active products. One enzyme of the lipoxygenase family, Arachidonate 15-lipoxygenase-1 (arachidonate:oxygen 15-oxidoreductase, EC 1.13.11.33), is implicated in several forms of epithelial cell cancers, and provides a ra...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-002-0066-8
更新日期：2002-06-01 00:00:00
abstract：:Medical treatments for lower urinary tract symptoms due to benign prostatic hyperplasia are frequently associated with changes in sexual function. While these medications are generally well-tolerated and have both reduced and delayed more invasive surgical options, the ramifications of long-term chronic use are largel...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-014-0441-2
更新日期：2014-10-01 00:00:00
abstract：PURPOSE OF REVIEW:There are an estimated 33 million men and women with overactive bladder (OAB) in the USA. Despite the prevalence of OAB, it remains a frequently misdiagnosed condition. OAB has shared symptomatology with other common urologic conditions, namely recurrent urinary tract infections (UTIs). Here, we will ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-018-0839-3
更新日期：2018-09-13 00:00:00
abstract：:Currently in the USA, one name is added to the organ transplant waiting list every 15 min. As this list grows rapidly, fewer than one-third of waiting patients can receive matched organs from donors. Unfortunately, many patients who require a transplant have to wait for long periods of time, and many of them die befor...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-017-0650-6
更新日期：2017-01-01 00:00:00
abstract：:Approximately one in seven American men will be diagnosed with prostate cancer during his lifetime, and at least 50% of newly diagnosed patients will present with low-risk disease. In the last decade, the decision-making paradigm for management has shifted due to high rates of disease detection and overtreatment, attr...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-015-0507-9
更新日期：2015-06-01 00:00:00
abstract：:The lack of reliable imaging tools in detecting prostate cancer makes a random biopsy still the standard of care to detect prostate cancer. To reduce the number of cores during a biopsy and therefore the risk of biopsy-related complications, an imaging tool which provides reliable guided biopsies is required. Transrec...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-013-0392-z
更新日期：2014-03-01 00:00:00
abstract：PURPOSE OF THE REVIEW:There is an abundance of evidence that the human microbiome plays an important and nuanced role in controlling human metabolism, immunity, and cancer. Herein we aim to review the most current research looking at prostate cancer and its link with the gut and genitourinary microbiome. There is now a...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-019-0922-4
更新日期：2019-09-07 00:00:00
abstract：:Partial nephrectomy has become an accepted treatment of cT1 renal masses as it provides improved long-term renal function compared to radical nephrectomy (Campbell et al. J Urol. 182:1271-9, 2009). Hilar clamping is utilized to help reduce bleeding and improve visibility during tumor resection. However, concern over r...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-016-0596-0
更新日期：2016-05-01 00:00:00
abstract：:Chronic nonbacterial prostatitis, or urological chronic pelvic pain syndrome (UCPPS), remains a common and often challenging disorder to evaluate and treat. Employing a more holistic approach, including urological therapy, physical therapy, and psychosocial perspectives, may be more appropriate for most patients. Grow...
journal_title：Current urology reports
pub_type： 杂志文章
doi：10.1007/s11934-009-0047-2
更新日期：2009-07-01 00:00:00
abstract：:High-intensity focused ultrasound (HIFU) is an emerging, noninvasive, local treatment of prostate cancer with 15 years of clinical experience, during which about 30,000 HIFU treatments have been performed worldwide. In this paper, we review relevant publications regarding the means by which new and old prostate cancer...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-011-0184-2
更新日期：2011-06-01 00:00:00
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journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-008-0042-z
更新日期：2008-05-01 00:00:00
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journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-019-0932-2
更新日期：2019-08-29 00:00:00
abstract：:Significant progress has been made over the past 15 years regarding the development of bladder control and the evaluation and management of pediatric voiding dysfunction. Incontinence is a problem of significant social consequence that is commonly due to dysfunctional voiding (ie, discoordination between the detrusor ...
journal_title：Current urology reports
pub_type： 杂志文章
doi：10.1007/s11934-010-0099-3
更新日期：2010-03-01 00:00:00
abstract：:Urgency and urinary urge incontinence are troublesome and complex symptoms that can complicate the diagnosis and treatment of stress urinary incontinence. Despite this fact, first-line intervention frequently is directed toward the incompetent bladder neck using surgical approaches. Persistent urgency or detrusor inst...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-004-0065-z
更新日期：2004-12-01 00:00:00
abstract：:The Infectious Diseases Society of America has published guidelines for the treatment of uncomplicated cystitis. Recommendations are that for healthy, adult, nonpregnant women with bacterial cystitis, 3 days of trimethoprim/ sulfamethoxazole (TMP/SMZ) or trimethoprim alone is standard therapy in those regions where le...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-001-0072-2
更新日期：2001-08-01 00:00:00
abstract：:Because the number of patients requiring oral anticoagulation (OA) is steadily growing, more and more patients requiring surgical treatment of benign prostatic hyperplasia (BPH) are on OA. Laser treatment of BPH was said to offer a higher quality of hemostasis than transurethral resection of the prostate (TURP). Thus,...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-010-0115-7
更新日期：2010-07-01 00:00:00
abstract：:Cancers of the prostate contribute substantial morbidity and mortality to the male population. The correlation of prostate cancer incidence with aging suggests that the disease burden associated with prostate carcinoma will increase dramatically over the next several decades. Despite the large number of fatalities dir...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-006-0039-4
更新日期：2006-01-01 00:00:00
abstract：:Benign prostatic hyperplasia (BPH) is the most common urologic affliction in aging men, leading to adverse clinical outcomes in a significant proportion of the population. Serum prostate-specific antigen (PSA) has been established as a marker for prostate cancer for the past two decades but more recently has been reco...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-007-0072-y
更新日期：2007-07-01 00:00:00
abstract：:The use of injectable bulking agents into the submucosal layer of the pediatric urinary tract continues to grow. Treatment strategies for vesicoureteral reflux and urinary incontinence have changed with the introduction of dextranomer/hyaluronic acid as a minimally invasive option. Socially and medically debilitating ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-006-0074-1
更新日期：2006-03-01 00:00:00
abstract：PURPOSE OF REVIEW:Amid the opioid crisis, postoperative pain management is a major challenge for practitioners. Recent pain management guidelines emphasize the importance of using regional anesthesia as part of opioid-sparing multimodal analgesia. This report aims to review recent evidence regarding the utilization of ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-019-0883-7
更新日期：2019-03-23 00:00:00
