Abstract:
:Currently in the USA, one name is added to the organ transplant waiting list every 15 min. As this list grows rapidly, fewer than one-third of waiting patients can receive matched organs from donors. Unfortunately, many patients who require a transplant have to wait for long periods of time, and many of them die before receiving the desired organ. In the USA alone, over 100,000 patients are waiting for a kidney transplant. However, it is a problem that affects around 6% of the word population. Therefore, seeking alternative solutions to this problem is an urgent work. Here, we review the current promising regenerative technologies for kidney function replacement. Despite many approaches being applied in the different ways outlined in this work, obtaining an organ capable of performing complex functions such as osmoregulation, excretion or hormone synthesis is still a long-term goal. However, in the future, the efforts in these areas may eliminate the long waiting list for kidney transplants, providing a definitive solution for patients with end-stage renal disease.
journal_name
Curr Urol Repjournal_title
Current urology reportsauthors
García-Domínguez X,Vicente JS,Vera-Donoso CD,Marco-Jimenez Fdoi
10.1007/s11934-017-0650-6subject
Has Abstractpub_date
2017-01-01 00:00:00pages
2issue
1eissn
1527-2737issn
1534-6285pii
10.1007/s11934-017-0650-6journal_volume
18pub_type
杂志文章,评审abstract::The use of injectable bulking agents into the submucosal layer of the pediatric urinary tract continues to grow. Treatment strategies for vesicoureteral reflux and urinary incontinence have changed with the introduction of dextranomer/hyaluronic acid as a minimally invasive option. Socially and medically debilitating ...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-006-0074-1
更新日期:2006-03-01 00:00:00
abstract::Correct staging of prostate cancer at initial diagnosis, as well as accurate staging and tumor localization with biochemical recurrence, remains generally inaccurate with current imaging techniques. Newer modalities are being investigated to accurately identify patients with prostate cancer at different stages of dise...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-006-0018-9
更新日期:2006-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Laparoscopic kidney surgery is commonly used for living donor, partial, and total tumor nephrectomy. The successful emergence of laparoscopic technique was justified by the many benefits offered such as reduced blood loss, tissue trauma, pain, and hospital stay. However, this comes at the expense of p...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-018-0757-4
更新日期:2018-01-18 00:00:00
abstract:PURPOSE OF REVIEW:This review summarizes the latest reports in inflatable penile prosthesis (IPP) complication management. RECENT FINDINGS:IPP complications are rare, and reports are limited to retrospective studies. However, recent multi-institutional studies and use of national databases have provided further insigh...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-019-0872-x
更新日期:2019-01-30 00:00:00
abstract::Increasing evidence recently has pointed toward a relationship between lower urinary tract symptoms (LUTS) and the presence of metabolic syndrome. This relationship has been supported by recent epidemiologic findings. Possible pathophysiologic links also have been proposed to explain the relationship between these two...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-996-0008-y
更新日期:2006-07-01 00:00:00
abstract::Preservation of postoperative urinary continence remains the primary concern of all men and their surgeons following robot-assisted radical prostatectomy (RARP). Without doubt, continence is the most important quality of life issue following radical prostatectomy. Identification of difficulties and lessons learned ove...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-012-0295-4
更新日期:2013-02-01 00:00:00
abstract::Overactive bladder (OAB) affects millions of people in the United States, and as the population ages, the prevalence of OAB will invariably increase. Conventional therapy for OAB includes behavioral modification and anticholinergic medication. OAB treatment comes with significant economic impact. With anticholinergic ...
journal_title:Current urology reports
pub_type: 杂志文章
doi:10.1007/s11934-009-0054-3
更新日期:2009-09-01 00:00:00
abstract::Neoadjuvant cisplatin-based combination chemotherapy is an established standard for resectable muscle-invasive bladder cancer, a disease with a pattern of predominantly distant and early recurrences. Pathologic complete remission appears to be an intermediate surrogate for survival when employing combination chemother...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-012-0236-2
更新日期:2012-04-01 00:00:00
abstract::Bulking therapy for stress urinary incontinence in women continues to evolve from the standpoint of material science. Several new materials have recently been subjected to clinical trials with the aim of assessing efficacy and safety of these agents for possible device registration. These new additions run the gamut o...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-006-0012-2
更新日期:2006-09-01 00:00:00
abstract::Prostate cancer is a key health concern for men with its etiology still under investigation. Recently, the role of dietary supplements has been noted to have a major inhibitory effect on prostate cancer and numerous studies have been conducted in this regard. This review provides a summary on numerous recent studies c...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-016-0637-8
更新日期:2016-11-01 00:00:00
abstract::The increased detection of incidental renal masses has introduced new challenges into the management of patients with newly discovered renal masses. Much interest has been focused on the diagnostic accuracy and the prognostic ability of imaging studies. These studies have elucidated trends that can guide management bu...
journal_title:Current urology reports
pub_type: 杂志文章
doi:10.1007/s11934-009-0004-0
更新日期:2009-01-01 00:00:00
abstract::Erectile dysfunction (ED) often is caused by endothelial dysfunction and may be a sign that a patient has vascular disease elsewhere in the body. Risk factors for coronary artery disease such as lipid abnormalities, smoking, diabetes, and hypertension also are risk factors for ED. Oral therapy for ED, such as sildenaf...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-003-0028-9
更新日期:2003-12-01 00:00:00
abstract::Erectile dysfunction (ED) is common after radical prostatectomy (RP). ED has a negative impact on health-related quality of life. Penile rehabilitation is defined as the use of any drug or device at or after RP to maximize erectile function recovery. The purpose of penile rehabilitation is the prevention of corpus cav...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-009-0037-4
更新日期:2009-05-01 00:00:00
abstract::As bladder reconstruction strategies evolve, a feasible and safe source of transplantable urothelium becomes a major consideration for patients with advanced bladder disease, particularly cancer. Pluripotent stem cells, such as embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), are attractive cand...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-014-0466-6
更新日期:2015-01-01 00:00:00
abstract::For many years, estrogen has been used to treat lower urinary tract dysfunction in postmenopausal women. The data supporting this practice vary. Large multi-institutional studies have shown little role for systemic estrogens in the treatment of urinary incontinence. Vaginal estrogen preparations show superiority to sy...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-011-0208-y
更新日期:2011-10-01 00:00:00
abstract::Congenital abnormalities, cancer, trauma, infection, inflammation, iatrogenic injuries, and other conditions may lead to genitourinary organ damage or loss, requiring eventual reconstruction. Tissue engineering follows the principles of cell transplantation, materials science, and engineering toward the development of...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-001-0030-z
更新日期:2001-02-01 00:00:00
abstract::Molecular imaging of prostate cancer is in a dynamic phase of development. Currently approved techniques are limited and researchers have been working on novel agents to improve accuracy in targeting and detecting prostate tumors. In addition, the complexity of various prostate cancer states also contributes to the ch...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-016-0575-5
更新日期:2016-03-01 00:00:00
abstract::Complementary and alternative medicine (CAM) has recently attracted national attention in the United States because of its widespread use and associated cost. CAM covers a broad spectrum of healing philosophies and approaches. Despite its widespread use, little is known about its safety, efficacy, cost effectiveness, ...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-001-0084-y
更新日期:2001-06-01 00:00:00
abstract:PURPOSE OF REVIEW:The symptoms of lower urinary tract dysfunction (LUTD) including urinary incontinence, frequency, and urgency are among the most common reasons children are referred to pediatric urologists. Despite this, the workup for LUTD is often time consuming and a source of frustration for patients, parents, an...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-018-0784-1
更新日期:2018-04-06 00:00:00
abstract::Overactive bladder syndrome continues to be a significant burden for the general population. Current first-line medical therapy often includes antimuscarinic medications designed for overactive bladder. Poor efficacy and significant side effects of these antimuscarinic medications have left patients and physicians loo...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-010-0134-4
更新日期:2010-09-01 00:00:00
abstract::Pediatric urolithiasis is on the rise globally and incidence rates have risen by 6-10% annually over the past couple of decades. Given the increasing incidence, high likelihood of recurrence, and long life expectancy of children, the use of ionizing radiation in the diagnosis, management, and follow up of pediatric ur...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-017-0669-8
更新日期:2017-03-01 00:00:00
abstract::Health information technology (HIT) is expected to transform the delivery of health care in the United States, but implementation and adoption vary widely across settings, specialties, and geographies. Significant barriers to high-level adoption persist despite federal incentives to hospitals and health-care providers...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-013-0356-3
更新日期:2013-12-01 00:00:00
abstract:PURPOSE OF REVIEW:The goal of this paper is to describe the pathophysiology of adult nocturnal enuresis and develop a generalized approach for evaluation and treatment. RECENT FINDINGS:Although nocturnal enuresis (NE) impacts a significant proportion of the adult population, research on this topic remains lacking. In ...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-020-00983-2
更新日期:2020-06-06 00:00:00
abstract:PURPOSE OF REVIEW:Although benign, renal angiomyolipoma (AML) may lead to serious complications without appropriate management. The purpose of this review is to describe the role of and evidence for interventional radiology techniques in the management of patients with AML. RECENT FINDINGS:For patients with renal mass...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-017-0687-6
更新日期:2017-05-01 00:00:00
abstract:PURPOSE OF REVIEW:We sought to determine whether infertile men can accurately be identified within a large insurance claims database to validate its use for reproductive health research. RECENT FINDINGS:Prior literature suggests that men coded for infertility are at higher risk for chronic disease though it was previo...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-017-0714-7
更新日期:2017-09-01 00:00:00
abstract::Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is the most common category of clinical prostatitis. The etiologic factors of CP/CPPS still remain unknown, and standard therapies often fail to achieve sustainable amelioration of symptoms; therefore, various treatment therapies have been approached. Recently...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-011-0186-0
更新日期:2011-08-01 00:00:00
abstract:PURPOSE OF REVIEW:The aim of this review is to describe the preoperative evaluation, surgical techniques, and postoperative management of patients with renal cell carcinoma (RCC) undergoing radical nephrectomy (RN) and inferior vena cava (IVC) thrombectomy. RECENT FINDINGS:RN and IVC thrombectomy remains the standard ...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-020-01007-9
更新日期:2020-10-22 00:00:00
abstract::Author Siamak Daneshmand would like to note that this article published in Current Urology Reports inadvertently did not disclose financial information that could possibly be a conflict of interest. ...
journal_title:Current urology reports
pub_type: 杂志文章,已发布勘误
doi:10.1007/s11934-019-0890-8
更新日期:2019-04-05 00:00:00
abstract::Surgical treatment of long urethral stricture disease remains one of the most challenging problems in urology. In recent years there has been continuous discussion with regard to the etiology, location, length, and management of extensive urethral stricture disease. Various tissues such as genital and extragenital ski...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-014-0424-3
更新日期:2014-08-01 00:00:00
abstract::For years the bladder epithelium has been the focus for diagnosing and treating the frequency, urgency, and pelvic pain of interstitial cystitis. However, many patients have not found symptom relief with these therapies. Pelvic floor dysfunction is often present in these patients, yet it is often untreated. Pelvic flo...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-006-0053-6
更新日期:2006-11-01 00:00:00