Abstract：
:As bladder reconstruction strategies evolve, a feasible and safe source of transplantable urothelium becomes a major consideration for patients with advanced bladder disease, particularly cancer. Pluripotent stem cells, such as embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), are attractive candidates from which to derive urothelium as they renew and proliferate indefinitely in vitro and fulfill the non-autologous and/or non-urologic criteria, respectively, that is required for many patients. This review presents the latest advancements in differentiating urothelium from pluripotent stem cells in vitro in the context of current bladder tissue engineering strategies.
journal_name
Curr Urol Repjournal_title
Current urology reportsauthors
Osborn SL,Kurzrock EAdoi
10.1007/s11934-014-0466-6subject
Has Abstractpub_date
2015-01-01 00:00:00pages
466issue
1eissn
1527-2737issn
1534-6285journal_volume
16pub_type
杂志文章,评审abstract：:The cholinergic system of the bladder includes muscarinic receptors distributed to detrusor myocytes and structures within mucosa including bladder afferent (sensory) nerves. The receptors have been shown to be involved in afferent signaling from the bladder, but it has not been established to what extent effects on t...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-008-0079-z
更新日期：2008-11-01 00:00:00
abstract：:Inflatable penile prosthesis (IPP) is an effective treatment for erectile dysfunction in patients' refractory to oral or injectable treatment. While the rate of infection has decreased over the past decade, it is still the most feared complication of IPP placement. Here, we assemble possible patient and surgical facto...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-015-0554-2
更新日期：2015-12-01 00:00:00
abstract：:Within the past 25 years, lasers have transitioned from merely destructive or ablative tools to those with reconstructive uses. It has been shown that the application of laser thermal energy to tissue will result in welding of the approximated areas. Furthermore, the addition of protein solder and chromophores (tissue...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-003-0058-3
更新日期：2003-02-01 00:00:00
abstract：:Numerous surgeries have been proposed for the treatment of genuine stress incontinence, with the goals to improve functional outcome and decrease complications and their associated morbidity. Two new, minimally invasive procedures, transvaginal retropubic urethropexy and transvaginal Cooper's ligament sling, are revie...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-996-0018-9
更新日期：2001-10-01 00:00:00
abstract：PURPOSE OF THE REVIEW:To update the most relevant literature regarding complex vascular cases in kidney transplant setting involving the graft, especially during the harvesting procedure and back-table preparation from the subsequent implant. RECENT FINDINGS:Challenging situations affecting the kidney graft such as mu...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-020-0955-8
更新日期：2020-01-31 00:00:00
abstract：BACKGROUND:Vesico-vaginal fistulae (VVF) remain the most prevalent genitourinary fistula detrimentally impacting quality of life. PURPOSE OF THE REVIEW:The purpose of this review is to examine relevant literature on management of VVF. RECENT FINDINGS:Obstructed labor is the leading cause of VVF in the developing worl...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-017-0708-5
更新日期：2017-08-01 00:00:00
abstract：PURPOSE OF REVIEW:The goal of this paper is to describe the pathophysiology of adult nocturnal enuresis and develop a generalized approach for evaluation and treatment. RECENT FINDINGS:Although nocturnal enuresis (NE) impacts a significant proportion of the adult population, research on this topic remains lacking. In ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-020-00983-2
更新日期：2020-06-06 00:00:00
abstract：:Robot-assisted surgery has changed the landscape of surgery. Implementation of robotics into most surgical specialties has left many educators challenged to develop the tools necessary to train and credential surgeons. Advances in robot-assisted surgery have led to the development of simulators and tools to assess ski...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-015-0508-8
更新日期：2015-06-01 00:00:00
abstract：PURPOSE OF REVIEW:Therapeutic options for the management of lower urinary tract symptoms (LUTS) secondary to benign prostatic enlargement (BPE) have considerably increased in recent years. However, the ideal timing to initiate medical treatment of LUTS/BPE has not been fully established. The aim of this review was to s...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-018-0823-y
更新日期：2018-07-09 00:00:00
abstract：:At present, it is reasonable to counsel all patients, as well as family members of patients, who have a palpable varicocele about the long-term risks for impaired fertility. Currently, no one can predict with absolute certainty if any adolescent with a varicocele will be at risk for future infertility. Based on existi...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-002-0019-2
更新日期：2002-04-01 00:00:00
abstract：PURPOSE OF REVIEW:Molecular characterization of cancer allows us to understand oncogenesis and clinical prognosis as well as facilitates development of biomarkers and treatment. Our aim was to review the current literature on genomic characterization of bladder cancer, and how far we are in implementing genomics into c...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-020-0960-y
更新日期：2020-03-13 00:00:00
abstract：:Benign prostatic hyperplasia (BPH) is one of the most common causes of lower urinary tract symptoms (LUTS) in aging men. Over the age of 60, more than a half of men have BPH and/or bothersome LUTS. Contemporary guidelines advocate surgery as the standard of care for symptomatic BPH after failure of medical therapy, wh...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-016-0601-7
更新日期：2016-06-01 00:00:00
abstract：:High-intensity focused ultrasound (HIFU) is an emerging, noninvasive, local treatment of prostate cancer with 15 years of clinical experience, during which about 30,000 HIFU treatments have been performed worldwide. In this paper, we review relevant publications regarding the means by which new and old prostate cancer...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-011-0184-2
更新日期：2011-06-01 00:00:00
abstract：PURPOSE OF REVIEW:Urethral reconstruction has evolved in the last several decades with the introduction of various techniques including fasciocutaneous skin flaps and buccal mucosal grafts. However, distal urethral strictures have continued to be a reconstructive challenge due to tendency for adverse cosmetic outcomes,...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-018-0792-1
更新日期：2018-04-17 00:00:00
abstract：PURPOSE OF REVIEW:There are an estimated 33 million men and women with overactive bladder (OAB) in the USA. Despite the prevalence of OAB, it remains a frequently misdiagnosed condition. OAB has shared symptomatology with other common urologic conditions, namely recurrent urinary tract infections (UTIs). Here, we will ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-018-0839-3
更新日期：2018-09-13 00:00:00
abstract：PURPOSE OF REVIEW:The goal of this paper was to review the novel treatment modality of high-intensity transurethral directional ultrasound for prostate cancer. RECENT FINDINGS:Prostate cancer is a heterogeneous disease with some patients electing for active surveillance and focal therapies instead of definitive treatm...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-020-01020-y
更新日期：2021-01-06 00:00:00
abstract：:Bladder cancer is the second commonest urinary tract malignancy with 70-80 % being non-muscle invasive (NMIBC) at diagnosis. Patients with high-risk NMIBC (T1/Tis, with high grade/G3, or CIS) represent a challenging group as they are at greater risk of recurrence and progression. Intravesical Bacilli Calmette-Guerin (...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-016-0625-z
更新日期：2016-09-01 00:00:00
abstract：:Surgical treatment of long urethral stricture disease remains one of the most challenging problems in urology. In recent years there has been continuous discussion with regard to the etiology, location, length, and management of extensive urethral stricture disease. Various tissues such as genital and extragenital ski...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-014-0424-3
更新日期：2014-08-01 00:00:00
abstract：:Several minimally invasive approaches to treatment of ureteropelvic junction obstruction are now in the urologist's armamentarium. This review provides in-depth analysis of endopyelotomy, endopyeloplasty, and laparoscopic pyeloplasty and suggests a treatment algorithm for proper patient selection to improve efficacy a...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-007-0064-y
更新日期：2007-03-01 00:00:00
abstract：:Cancers of the prostate contribute substantial morbidity and mortality to the male population. The correlation of prostate cancer incidence with aging suggests that the disease burden associated with prostate carcinoma will increase dramatically over the next several decades. Despite the large number of fatalities dir...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-006-0039-4
更新日期：2006-01-01 00:00:00
abstract：:Peyronie's disease (PD) is the occurrence of a fibrous inelastic scar of the tunica albuginea of the penis. It is a relatively common disorder among men, with a reported prevalence of 3% to 8%. It is often associated with penile pain, anatomical deformities in the erect state, and difficulty with intromission. Because...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-011-0212-2
更新日期：2011-12-01 00:00:00
abstract：PURPOSE OF REVIEW:The symptoms of lower urinary tract dysfunction (LUTD) including urinary incontinence, frequency, and urgency are among the most common reasons children are referred to pediatric urologists. Despite this, the workup for LUTD is often time consuming and a source of frustration for patients, parents, an...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-018-0784-1
更新日期：2018-04-06 00:00:00
abstract：PURPOSE OF REVIEW:Although benign, renal angiomyolipoma (AML) may lead to serious complications without appropriate management. The purpose of this review is to describe the role of and evidence for interventional radiology techniques in the management of patients with AML. RECENT FINDINGS:For patients with renal mass...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-017-0687-6
更新日期：2017-05-01 00:00:00
abstract：:The quality of functional outcome has become increasingly important in view of improvement in prognosis with colorectal cancer patients. Sexual dysfunction remains a common problem after colorectal cancer treatment, despite the good oncologic outcomes achieved by expert surgeons. Although radiotherapy and chemotherapy...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-013-0341-x
更新日期：2013-08-01 00:00:00
abstract：:The most common form of prostatitis is National Institutes of Health category III, also known as chronic abacterial prostatitis/chronic pelvic pain syndrome. The search for effective and durable therapy for this condition remains frustrating for both patients and physicians. A new approach incorporating a neurobahavio...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-000-0051-z
更新日期：2000-08-01 00:00:00
abstract：PURPOSE OF REVIEW:This review summarizes the latest reports in inflatable penile prosthesis (IPP) complication management. RECENT FINDINGS:IPP complications are rare, and reports are limited to retrospective studies. However, recent multi-institutional studies and use of national databases have provided further insigh...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-019-0872-x
更新日期：2019-01-30 00:00:00
abstract：:The development of a lymphocele after pelvic surgery is a well-documented complication, especially where pelvic lymph node dissection (PLND) is part of the operation. However, not all lymphoceles are symptomatic and require treatment. Most lymphoceles spontaneously resolve, and even lymphoceles that become symptomatic...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-014-0445-y
更新日期：2014-10-01 00:00:00
abstract：:Prostate cancer is a key health concern for men with its etiology still under investigation. Recently, the role of dietary supplements has been noted to have a major inhibitory effect on prostate cancer and numerous studies have been conducted in this regard. This review provides a summary on numerous recent studies c...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-016-0637-8
更新日期：2016-11-01 00:00:00
abstract：:Benign prostatic hyperplasia (BPH) is the most common urologic affliction in aging men, leading to adverse clinical outcomes in a significant proportion of the population. Serum prostate-specific antigen (PSA) has been established as a marker for prostate cancer for the past two decades but more recently has been reco...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-007-0072-y
更新日期：2007-07-01 00:00:00
abstract：:Each of the three most common contemporary treatments for localized prostate cancer, radical prostatectomy, external beam radiotherapy, and brachytherapy, can have adverse effects on sexual health. Sexual health outcome can be improved by treatment-specific factors, such as the use of nerve-sparing technique during ra...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-004-0039-1
更新日期：2004-06-01 00:00:00
