Abstract：
PURPOSE OF REVIEW:While recurrence after primary treatment of prostate cancer (PCa) is not uncommon, there is currently no consensus on the most appropriate management after radiation treatment failure. This article seeks to explore the currently utilized modalities for salvage treatment for radiorecurrent PCa. We focused our review on the oncologic outcomes and reported toxicity rates in the latest studies examining salvage radical prostatectomy (SRP), salvage cryotherapy (SCT), salvage high-intensity focused ultrasound (HIFU) and re-irradiation. RECENT FINDINGS:There does not appear to be any significant difference in overall survival for more invasive salvage radical prostatectomy compared to the minimally invasive salvage approaches. Additionally, there seems to be a trend towards lower morbidity rates associated with minimally invasive and focal salvage treatment. We are encouraged by the results presented in this review and find that there is clearly a role for emerging minimally invasive and focal therapies as durable options for salvage treatment in patients with radiorecurrent PCa.
journal_name
Curr Urol Repjournal_title
Current urology reportsauthors
Golbari NM,Katz AEdoi
10.1007/s11934-017-0709-4subject
Has Abstractpub_date
2017-08-01 00:00:00pages
63issue
8eissn
1527-2737issn
1534-6285pii
10.1007/s11934-017-0709-4journal_volume
18pub_type
杂志文章,评审abstract：PURPOSE OF REVIEW:This review provides a critical literature overview of the risks and benefits of transplantectomy in patients with a failed allograft. Additionally, it offers a summary of related problems, primarily alloantibody sensitization in the event of nephrectomy and immunosuppression weaning. RECENT FINDINGS...
journal_title：Current urology reports
pub_type： 杂志文章
doi：10.1007/s11934-020-0957-6
更新日期：2020-01-18 00:00:00
abstract：:Bladder outlet obstruction (BOO) in women can be either anatomic or functional. Anatomic causes for BOO are often readily apparent by history and physical exam. On the other hand, causes for functional obstruction, including dysfunctional voiding, primary bladder neck obstruction, and detrusor-external sphincter dyssy...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-012-0267-8
更新日期：2012-10-01 00:00:00
abstract：:Positioning injuries in the perioperative period are one of the inherent risks of surgery, but particularly in robot-assisted urologic surgery, and can result in often unrecognized morbidity. Injuries such as upper or lower extremity peripheral neuropathies occur via neural mechanisms and injuries such as compartment ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-014-0398-1
更新日期：2014-04-01 00:00:00
abstract：:Overactive bladder (OAB) affects millions of people in the United States, and as the population ages, the prevalence of OAB will invariably increase. Conventional therapy for OAB includes behavioral modification and anticholinergic medication. OAB treatment comes with significant economic impact. With anticholinergic ...
journal_title：Current urology reports
pub_type： 杂志文章
doi：10.1007/s11934-009-0054-3
更新日期：2009-09-01 00:00:00
abstract：:Numerous surgeries have been proposed for the treatment of genuine stress incontinence, with the goals to improve functional outcome and decrease complications and their associated morbidity. Two new, minimally invasive procedures, transvaginal retropubic urethropexy and transvaginal Cooper's ligament sling, are revie...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-996-0018-9
更新日期：2001-10-01 00:00:00
abstract：:Urgency and urinary urge incontinence are troublesome and complex symptoms that can complicate the diagnosis and treatment of stress urinary incontinence. Despite this fact, first-line intervention frequently is directed toward the incompetent bladder neck using surgical approaches. Persistent urgency or detrusor inst...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-004-0065-z
更新日期：2004-12-01 00:00:00
abstract：:Significant clinical and basic science advances in the field of sexual medicine have facilitated investigation of the link between endothelial dysfunction and erectile dysfunction. Most sexual medicine practitioners accept the premise that in aging men with risk factors such as increased waist circumference, diabetes,...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-007-0054-0
更新日期：2007-11-01 00:00:00
abstract：PURPOSE OF REVIEW:Intratumor heterogeneity is an inherent event in tumor development that is receiving much attention in the last years since it is responsible for most failures of current targeted therapies. The purpose of this review is to offer clinicians an updated insight of the multiple manifestations of a comple...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-018-0754-7
更新日期：2018-01-27 00:00:00
abstract：:The objective of this review is to discuss the main goals of pelvic organ prolapse repair. Pelvic organ prolapse symptoms are variable, and prolapse degree does not necessarily correlate with perceived symptoms or other associated conditions including urinary, defecatory, and sexual dysfunction. Treatment for pelvic o...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-013-0385-y
更新日期：2014-02-01 00:00:00
abstract：:Robot-assisted surgery has changed the landscape of surgery. Implementation of robotics into most surgical specialties has left many educators challenged to develop the tools necessary to train and credential surgeons. Advances in robot-assisted surgery have led to the development of simulators and tools to assess ski...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-015-0508-8
更新日期：2015-06-01 00:00:00
abstract：:Benign prostatic hyperplasia (BPH) is a disease condition characterized by abnormal prostate growth in conjunction with distinct lower urinary tract symptoms. This paper considers the extent to which the prostatic vascular system contributes to normal prostate growth control as well as whether abnormal blood flow patt...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-002-0051-2
更新日期：2002-08-01 00:00:00
abstract：:Benign prostatic hyperplasia (BPH) is the most common urologic affliction in aging men, leading to adverse clinical outcomes in a significant proportion of the population. Serum prostate-specific antigen (PSA) has been established as a marker for prostate cancer for the past two decades but more recently has been reco...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-007-0072-y
更新日期：2007-07-01 00:00:00
abstract：:Currently in the USA, one name is added to the organ transplant waiting list every 15 min. As this list grows rapidly, fewer than one-third of waiting patients can receive matched organs from donors. Unfortunately, many patients who require a transplant have to wait for long periods of time, and many of them die befor...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-017-0650-6
更新日期：2017-01-01 00:00:00
abstract：:Recent studies have cast doubt on the reliability of serum total prostate-specific antigen as a biomarker for the detection and prognosis of prostate cancer. Biomarkers that can identify those men at risk for clinically significant prostate cancer are desperately needed. The search for biomarkers that may improve the ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-005-0004-7
更新日期：2005-05-01 00:00:00
abstract：:Adrenal hemorrhage is a rare yet potentially life-threatening event that occurs both in traumatic conditions and in a variety of nontraumatic conditions. Clinical manifestations of adrenal hemorrhage can vary widely depending on the degree and rate of hemorrhage, as well as the amount of adrenal cortex compromised by ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-009-0014-y
更新日期：2009-01-01 00:00:00
abstract：:Complementary and alternative medicine (CAM) has recently attracted national attention in the United States because of its widespread use and associated cost. CAM covers a broad spectrum of healing philosophies and approaches. Despite its widespread use, little is known about its safety, efficacy, cost effectiveness, ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-001-0084-y
更新日期：2001-06-01 00:00:00
abstract：:Adolescents with varicoceles represent a large and heterogeneous group. This patient population has rapidly changing hormonal levels and may present at different stages of physical and pubertal development. At the same time, the adolescent varicocele is becoming a more widely appreciated and diagnosed entity with an e...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-009-0026-7
更新日期：2009-03-01 00:00:00
abstract：PURPOSE OF REVIEW:The clinical role of fluorine-18 fluoro-2-deoxyglucose (FDG)-positron emission tomography (PET) in renal cell carcinoma (RCC) is still evolving. Use of FDG PET in RCC is currently not a standard investigation in the diagnosis and staging of RCC due to its renal excretion. This review focuses on the cl...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-019-0932-2
更新日期：2019-08-29 00:00:00
abstract：PURPOSE OF THE REVIEW:This review targets the latest literature on bladder preservation therapy with emphasis on trimodal therapy (TMT), highlighting its role in the management of muscle invasive bladder cancer (MIBC) and outlining future directions in bladder preservation research. RECENT FINDINGS:TMT is the most pro...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-018-0859-z
更新日期：2018-11-03 00:00:00
abstract：:For many years, estrogen has been used to treat lower urinary tract dysfunction in postmenopausal women. The data supporting this practice vary. Large multi-institutional studies have shown little role for systemic estrogens in the treatment of urinary incontinence. Vaginal estrogen preparations show superiority to sy...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-011-0208-y
更新日期：2011-10-01 00:00:00
abstract：:Androgen deprivation therapy (ADT) is a well-established treatment for locally advanced, biochemically recurrent and metastatic prostate cancer. However, it is associated with significant side effects including hot flashes, loss of libido and erectile function, muscular atrophy, metabolic abnormalities, and osteoporos...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-015-0481-2
更新日期：2015-03-01 00:00:00
abstract：:The development of a lymphocele after pelvic surgery is a well-documented complication, especially where pelvic lymph node dissection (PLND) is part of the operation. However, not all lymphoceles are symptomatic and require treatment. Most lymphoceles spontaneously resolve, and even lymphoceles that become symptomatic...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-014-0445-y
更新日期：2014-10-01 00:00:00
abstract：:Congenital abnormalities, cancer, trauma, infection, inflammation, iatrogenic injuries, and other conditions may lead to genitourinary organ damage or loss, requiring eventual reconstruction. Tissue engineering follows the principles of cell transplantation, materials science, and engineering toward the development of...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-001-0030-z
更新日期：2001-02-01 00:00:00
abstract：PURPOSE OF REVIEW:Bladder cancer care is costly due to long surveillance periods for non-muscle-invasive bladder cancer (NMIBC) and comorbidities associated with the surgical treatment of muscle-invasive bladder cancer (MIBC). We reviewed current evidence-based practices and propose quality metrics for NMIBC and MIBC. ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-018-0856-2
更新日期：2018-10-24 00:00:00
abstract：:The prostate-specific antigen (PSA) era has increased the rates of prostate cancer detection and treatment, while reducing the risk of death from prostate cancer in the US. Image-guided prostate biopsy techniques have led to stage migration and the detection and treatment of lower risk prostate cancers. Improved techn...
journal_title：Current urology reports
pub_type： 杂志文章
doi：10.1007/s11934-012-0285-6
更新日期：2012-12-01 00:00:00
abstract：PURPOSE OF REVIEW:Patient-reported outcome measures (PROMs) are tools that are widely used by clinicians and researchers across different medical specialties. In this review, we examine the use of PROMs in the evaluation of female pelvic floor disorders (PFD). RECENT FINDINGS:PROM development in the assessment of urin...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-019-0888-2
更新日期：2019-03-27 00:00:00
abstract：:Testosterone (T) deficiency syndrome (TDS) is a prevalent condition, commonly managed with exogenous T. Despite an abundance of T formulations, alternative treatments are often sought for various reasons. To evaluate outcomes of alternative therapies, a PubMed search was performed of all publications that included men...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-014-0417-2
更新日期：2014-07-01 00:00:00
abstract：:At present, it is reasonable to counsel all patients, as well as family members of patients, who have a palpable varicocele about the long-term risks for impaired fertility. Currently, no one can predict with absolute certainty if any adolescent with a varicocele will be at risk for future infertility. Based on existi...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-002-0019-2
更新日期：2002-04-01 00:00:00
abstract：:Robot-assisted surgery has become a widely used surgical approach in the management of urologic malignancies. With its initial experience in the treatment of prostate cancer, the technology rapidly expanded to other urologic malignancies including bladder cancer. Since its introduction in 2003, robot-assisted radical ...
journal_title：Current urology reports
pub_type： 杂志文章,评审
doi：10.1007/s11934-016-0598-y
更新日期：2016-06-01 00:00:00
abstract：:Chronic nonbacterial prostatitis, or urological chronic pelvic pain syndrome (UCPPS), remains a common and often challenging disorder to evaluate and treat. Employing a more holistic approach, including urological therapy, physical therapy, and psychosocial perspectives, may be more appropriate for most patients. Grow...
journal_title：Current urology reports
pub_type： 杂志文章
doi：10.1007/s11934-009-0047-2
更新日期：2009-07-01 00:00:00
