Abstract:
:There is substantial variability in the extent of the node dissection performed during radical cystectomy for bladder cancer. Here, we review the diagnostic assessment of lymph node metastasis and the prognostic and therapeutic benefit for pelvic node dissection for bladder cancer. A review of the applicable urologic literature regarding the topics of lymphadenectomy for bladder cancer was conducted. Nodal metastasis above a limited or standard template is not uncommon, with up to 16% of all nodal metastasis detected proximal to the aortic bifurcation. However, skip metastasis is extremely rare. Proteins associated purely with epithelial tissue such as cytokeratin (CK)-19, CK-20, and uroplakin II have been observed in reportedly negative nodal specimens, which indicates that routine microscopic analysis of nodal tissue may miss small foci of metastatic cancer. In addition to the surgical technique, the total number of lymph nodes removed is influenced by patient anatomy and pathologic processing and therefore may be unsuitable as a procedural quality statement. Consecutively, meticulous removal of tissue within a defined and uniformly applied template may be more relevant than absolute nodal count. Observational cohort series indicate an improved oncologic outcome for patients undergoing extensive nodal dissection. The results of two randomized controlled trials addressing the extent of nodal dissection for bladder cancer are forthcoming.
journal_name
Curr Urol Repjournal_title
Current urology reportsauthors
Svatek R,Zehnder Pdoi
10.1007/s11934-012-0235-3subject
Has Abstractpub_date
2012-04-01 00:00:00pages
115-21issue
2eissn
1527-2737issn
1534-6285journal_volume
13pub_type
杂志文章,评审abstract::Preservation of postoperative urinary continence remains the primary concern of all men and their surgeons following robot-assisted radical prostatectomy (RARP). Without doubt, continence is the most important quality of life issue following radical prostatectomy. Identification of difficulties and lessons learned ove...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-012-0295-4
更新日期:2013-02-01 00:00:00
abstract::Within the past 25 years, lasers have transitioned from merely destructive or ablative tools to those with reconstructive uses. It has been shown that the application of laser thermal energy to tissue will result in welding of the approximated areas. Furthermore, the addition of protein solder and chromophores (tissue...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-003-0058-3
更新日期:2003-02-01 00:00:00
abstract::Partial nephrectomy has become an accepted treatment of cT1 renal masses as it provides improved long-term renal function compared to radical nephrectomy (Campbell et al. J Urol. 182:1271-9, 2009). Hilar clamping is utilized to help reduce bleeding and improve visibility during tumor resection. However, concern over r...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-016-0596-0
更新日期:2016-05-01 00:00:00
abstract::Most children born with spina bifida, the most common disabling congenital abnormality, have normal renal function. If left untreated, more than half of these children will have serious renal deterioration by age 5. This deterioration is secondary to hostile neurogenic changes of the bladder. Renal development should ...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-008-0027-y
更新日期:2008-03-01 00:00:00
abstract::The development of a lymphocele after pelvic surgery is a well-documented complication, especially where pelvic lymph node dissection (PLND) is part of the operation. However, not all lymphoceles are symptomatic and require treatment. Most lymphoceles spontaneously resolve, and even lymphoceles that become symptomatic...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-014-0445-y
更新日期:2014-10-01 00:00:00
abstract::Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is the most common category of clinical prostatitis. The etiologic factors of CP/CPPS still remain unknown, and standard therapies often fail to achieve sustainable amelioration of symptoms; therefore, various treatment therapies have been approached. Recently...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-011-0186-0
更新日期:2011-08-01 00:00:00
abstract::Patients diagnosed with prostate cancer who elect to pursue active treatment of their disease must choose among the many available treatment alternatives. Several treatment options now exist for similar-stage disease (clinical T1-3N0M0), including radical prostatectomy, external beam radiation, prostate brachytherapy ...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-000-0034-0
更新日期:2000-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Amid the opioid crisis, postoperative pain management is a major challenge for practitioners. Recent pain management guidelines emphasize the importance of using regional anesthesia as part of opioid-sparing multimodal analgesia. This report aims to review recent evidence regarding the utilization of ...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-019-0883-7
更新日期:2019-03-23 00:00:00
abstract:PURPOSE OF REVIEW:To discuss considerations and current evidence for the diagnosis and management of vaginal mesh exposures following female mesh-augmented anti-incontinence and pelvic organ prolapse surgery. RECENT FINDINGS:Since the introduction of mesh into female pelvic surgery, various applications have been repo...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-020-01002-0
更新日期:2020-10-30 00:00:00
abstract::Testosterone (T) deficiency syndrome (TDS) is a prevalent condition, commonly managed with exogenous T. Despite an abundance of T formulations, alternative treatments are often sought for various reasons. To evaluate outcomes of alternative therapies, a PubMed search was performed of all publications that included men...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-014-0417-2
更新日期:2014-07-01 00:00:00
abstract::Cancers of the prostate contribute substantial morbidity and mortality to the male population. The correlation of prostate cancer incidence with aging suggests that the disease burden associated with prostate carcinoma will increase dramatically over the next several decades. Despite the large number of fatalities dir...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-006-0039-4
更新日期:2006-01-01 00:00:00
abstract::Peyronie's disease is an acquired condition that presents clinically with a palpable induration, a distinct plaque, or a curvature of the erect penis. At times, the erections are painful. Erectile dysfunction (ED) often is associated with Peyronie's disease. The current era of phosphodiesterase therapy for the treatme...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-005-0041-2
更新日期:2005-11-01 00:00:00
abstract:PURPOSE OF REVIEW:The clinical role of fluorine-18 fluoro-2-deoxyglucose (FDG)-positron emission tomography (PET) in renal cell carcinoma (RCC) is still evolving. Use of FDG PET in RCC is currently not a standard investigation in the diagnosis and staging of RCC due to its renal excretion. This review focuses on the cl...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-019-0932-2
更新日期:2019-08-29 00:00:00
abstract::Bladder outlet obstruction (BOO) in women can be either anatomic or functional. Anatomic causes for BOO are often readily apparent by history and physical exam. On the other hand, causes for functional obstruction, including dysfunctional voiding, primary bladder neck obstruction, and detrusor-external sphincter dyssy...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-012-0267-8
更新日期:2012-10-01 00:00:00
abstract::Peyronie's disease (PD) is the occurrence of a fibrous inelastic scar of the tunica albuginea of the penis. It is a relatively common disorder among men, with a reported prevalence of 3% to 8%. It is often associated with penile pain, anatomical deformities in the erect state, and difficulty with intromission. Because...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-011-0212-2
更新日期:2011-12-01 00:00:00
abstract::Non-muscle-invasive bladder cancer is characterized by frequent recurrences requiring repeated transurethral resections and carries a risk of progression to muscle-invasive disease. The routinely used, passive diffusion irrigation of the bladder with mitomycin C has achieved limited success in avoiding these events. W...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-012-0302-9
更新日期:2013-04-01 00:00:00
abstract:PURPOSE OF REVIEW:Although benign, renal angiomyolipoma (AML) may lead to serious complications without appropriate management. The purpose of this review is to describe the role of and evidence for interventional radiology techniques in the management of patients with AML. RECENT FINDINGS:For patients with renal mass...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-017-0687-6
更新日期:2017-05-01 00:00:00
abstract::Approximately one in seven American men will be diagnosed with prostate cancer during his lifetime, and at least 50% of newly diagnosed patients will present with low-risk disease. In the last decade, the decision-making paradigm for management has shifted due to high rates of disease detection and overtreatment, attr...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-015-0507-9
更新日期:2015-06-01 00:00:00
abstract:PURPOSE OF REVIEW:The purpose of the study is to review and summarize major additions to the literature as pertains to enhanced recovery protocols after radical cystectomy in the past year. RECENT FINDINGS:Enhanced recovery after surgery protocols is multimodal pathways that include elements to optimize all stages of ...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-018-0855-3
更新日期:2018-10-18 00:00:00
abstract::Lipoxygenases oxidatively metabolize polyunsaturated fatty acids to a rich spectrum of biologically active products. One enzyme of the lipoxygenase family, Arachidonate 15-lipoxygenase-1 (arachidonate:oxygen 15-oxidoreductase, EC 1.13.11.33), is implicated in several forms of epithelial cell cancers, and provides a ra...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-002-0066-8
更新日期:2002-06-01 00:00:00
abstract:PURPOSE OF REVIEW:Molecular characterization of cancer allows us to understand oncogenesis and clinical prognosis as well as facilitates development of biomarkers and treatment. Our aim was to review the current literature on genomic characterization of bladder cancer, and how far we are in implementing genomics into c...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-020-0960-y
更新日期:2020-03-13 00:00:00
abstract::DNA microarray technology provides a means to examine large numbers of molecular changes related to a biological process in a high throughput manner. This review discusses plausible utilities of this technology in prostate cancer research, including definition of prostate cancer predisposition, global profiling of gen...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-002-0011-x
更新日期:2002-02-01 00:00:00
abstract:PURPOSE OF REVIEW:Urethral strictures that are refractory to initial management present unique challenges to the reconstructive surgeon. Treatment trends have shifted as new tissue resources are becoming available. There is renewed interest in old methods as skill and technique have improved. We describe the scope of t...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-018-0769-0
更新日期:2018-02-26 00:00:00
abstract::Medical treatments for lower urinary tract symptoms due to benign prostatic hyperplasia are frequently associated with changes in sexual function. While these medications are generally well-tolerated and have both reduced and delayed more invasive surgical options, the ramifications of long-term chronic use are largel...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-014-0441-2
更新日期:2014-10-01 00:00:00
abstract::The use of injectable bulking agents into the submucosal layer of the pediatric urinary tract continues to grow. Treatment strategies for vesicoureteral reflux and urinary incontinence have changed with the introduction of dextranomer/hyaluronic acid as a minimally invasive option. Socially and medically debilitating ...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-006-0074-1
更新日期:2006-03-01 00:00:00
abstract::Health information technology (HIT) is expected to transform the delivery of health care in the United States, but implementation and adoption vary widely across settings, specialties, and geographies. Significant barriers to high-level adoption persist despite federal incentives to hospitals and health-care providers...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-013-0356-3
更新日期:2013-12-01 00:00:00
abstract::The most important change in urology during the past decade was the development of minimally invasive surgery, particularly laparoscopy. However, the main drawback of laparoscopy is a steep learning curve, which results from the significant changes in the surgical environment. Although laparoscopy can provide importan...
journal_title:Current urology reports
pub_type: 杂志文章
doi:10.1007/s11934-003-0040-0
更新日期:2003-04-01 00:00:00
abstract::The increased detection of incidental renal masses has introduced new challenges into the management of patients with newly discovered renal masses. Much interest has been focused on the diagnostic accuracy and the prognostic ability of imaging studies. These studies have elucidated trends that can guide management bu...
journal_title:Current urology reports
pub_type: 杂志文章
doi:10.1007/s11934-009-0004-0
更新日期:2009-01-01 00:00:00
abstract:PURPOSE OF REVIEW:Patient-reported outcome measures (PROMs) are tools that are widely used by clinicians and researchers across different medical specialties. In this review, we examine the use of PROMs in the evaluation of female pelvic floor disorders (PFD). RECENT FINDINGS:PROM development in the assessment of urin...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-019-0888-2
更新日期:2019-03-27 00:00:00
abstract::Global improvements in water quality, management of infectious diseases, and other medical therapeutics have resulted in a growing population of healthy aging men. One obligate anatomic consequence of aging for these men is the development of benign prostatic hyperplasia (BPH) with secondary bladder outlet obstruction...
journal_title:Current urology reports
pub_type: 杂志文章,评审
doi:10.1007/s11934-014-0403-8
更新日期:2014-05-01 00:00:00