Importance of Providencia species as a major cause of travellers' diarrhoea.

Abstract:

:In this study the importance of Providencia species as a cause of travellers' diarrhoea was examined using a selective medium developed by the authors. Providencia species could easily be distinguished from other enteric pathogens by the colour of the colonies obtained. Nine strains of Providencia alcalifaciens, nine of Providencia rettgeri and five of Providencia stuartii were isolated from 130 specimens, representing a surprisingly high incidence of infection compared with other pathogens isolated on SS agar and TCBS agar. Patients infected with P. rettgeri complained of abdominal pain, as for other Providencia species, but also of vomiting, which is rather characteristic of P. rettgeri infection. To analyse the pathogenicity of these isolates, their invasiveness was examined using Caco-2 cells. Most of the P. rettgeri strains invaded Caco-2 cells. Random amplified polymorphic DNA (RAPD) fingerprinting showed the same profile for two P. rettgeri isolates from individuals travelling in the same tour group. The results show that Providencia species, especially P. rettgeri, might cause diarrhoea, and that these species are important pathogens.

journal_name

J Med Microbiol

authors

Yoh M,Matsuyama J,Ohnishi M,Takagi K,Miyagi H,Mori K,Park KS,Ono T,Honda T

doi

10.1099/jmm.0.45846-0

keywords:

subject

Has Abstract

pub_date

2005-11-01 00:00:00

pages

1077-1082

issue

Pt 11

eissn

0022-2615

issn

1473-5644

journal_volume

54

pub_type

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