Hydrogen sulphide and the hyperdynamic circulation in cirrhosis: a hypothesis.

abstract：:Intestinal involvement in Schistosoma mansoni infection is usually confined to the ileum and colon. Duodenal infestation was diagnosed in a patient with recurrent schistosomiasis despite treatment who presented with a postoperative small bowel fistula. Duodenal schistosomiasis can be suspected on endoscopy, but must a...

journal_title：Gut

authors： Contractor QQ,Benson L,Schulz TB,Contractor TQ,Kasturi N

更新日期：1988-07-01 00:00:00

abstract：OBJECTIVES:Novel imaging methods based on specific molecular targets to detect both established neoplasms and their precursor lesions are highly desirable in cancer medicine. Previously, we identified claudin-4, an integral constituent of tight junctions, as highly expressed in various gastrointestinal tumours includin...

journal_title：Gut

authors： Neesse A,Hahnenkamp A,Griesmann H,Buchholz M,Hahn SA,Maghnouj A,Fendrich V,Ring J,Sipos B,Tuveson DA,Bremer C,Gress TM,Michl P

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:We have previously shown that hypnosis can be used to study the effect of different emotions on the motility of the gastrointestinal tract. These studies demonstrated that both anger and excitement increased colonic motility while happiness led to a reduction. The purpose of this study was to ...

journal_title：Gut

authors： Houghton LA,Calvert EL,Jackson NA,Cooper P,Whorwell PJ

更新日期：2002-11-01 00:00:00

abstract：:A case is described of primary biliary cirrhosis in a 59 year old woman who initially presented with a rash over her lower legs 18 months before diagnosis. Skin biopsy examination showed non-caseating granulomas of the sarcoid type. It is believed that this is the first reported case of primary biliary cirrhosis prese...

journal_title：Gut

authors： Jardine DL,Chambers ST,Hart DJ,Chapman BA

更新日期：1994-04-01 00:00:00

abstract：OBJECTIVE:Hepatocellular carcinoma (HCC) is a heterogeneous tumour displaying a complex variety of genetic and epigenetic changes. In human cancers, aberrant post-transcriptional modifications, such as alternative splicing and RNA editing, may lead to tumour specific transcriptome diversity. DESIGN:By utilising large ...

journal_title：Gut

authors： Chan TH,Lin CH,Qi L,Fei J,Li Y,Yong KJ,Liu M,Song Y,Chow RK,Ng VH,Yuan YF,Tenen DG,Guan XY,Chen L

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND AND AIM:Colorectal cancer (CRC) is a multifactorial disease with both environmental and genetic factors contributing to its development. The incidence of CRC is increasing year by year in Japan. Patients with CRC in advanced stages have a poor prognosis, but detection of CRC at earlier stages can improve cli...

journal_title：Gut

authors： Cui R,Okada Y,Jang SG,Ku JL,Park JG,Kamatani Y,Hosono N,Tsunoda T,Kumar V,Tanikawa C,Kamatani N,Yamada R,Kubo M,Nakamura Y,Matsuda K

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:Intestinal permeability and psychological stress have been implicated in the pathophysiology of IBD and IBS. Studies in animals suggest that stress increases permeability via corticotropin-releasing hormone (CRH)-mediated mast cell activation. Our aim was to investigate the effect of stress on intestinal perm...

journal_title：Gut

authors： Vanuytsel T,van Wanrooy S,Vanheel H,Vanormelingen C,Verschueren S,Houben E,Salim Rasoel S,Tόth J,Holvoet L,Farré R,Van Oudenhove L,Boeckxstaens G,Verbeke K,Tack J

更新日期：2014-08-01 00:00:00

abstract：:Carcinoembryonic antigen (CEA) levels have been measured in the serum of 490 patients and 93 normal controls using the double antibody radioimmunoassay technique. Levels were elevated in 71 of patients with carcinomata of the gastrointestinal tract and in 42% with other types of malignancy. In patients with non-neopla...

journal_title：Gut

authors： Booth SN,King JP,Leonard JC,Dykes PW

更新日期：1973-10-01 00:00:00

abstract：:The absorption of short chain fatty acids by the human rectum in the absence of chloride has been studied using a dialysis bag technique. Absorption rates of sodium, water, and short chain fatty acids were unchanged on replacing chloride with sulphate. Final concentrations of bicarbonate were 35.4 +/- 3.4 mmol/l in th...

journal_title：Gut

authors： McNeil NI,Cummings JH,James WP

更新日期：1979-05-01 00:00:00

abstract：BACKGROUND:Ethanol undergoes a first pass metabolism (FPM) in the stomach and liver. Gastric FPM of ethanol primarily depends on the activity of gastric alcohol dehydrogenase (ADH). In addition, the speed of gastric emptying (GE) may modulate both gastric and hepatic FPM of ethanol. AIMS:To study the effect of modulat...

journal_title：Gut

authors： Oneta CM,Simanowski UA,Martinez M,Allali-Hassani A,Parés X,Homann N,Conradt C,Waldherr R,Fiehn W,Coutelle C,Seitz HK

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:Cholera toxin produces intestinal secretion by activation of the adenylate cyclase complex. However animal studies have shown 5-hydroxytryptamine may be released after exposure to cholera toxin, and thereby contribute to the secretory state. AIM:To determine whether cholera toxin releases 5-hydroxytryptamin...

journal_title：Gut

authors： Bearcroft CP,Perrett D,Farthing MJ

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:The mechanisms of aspirin induced gastroduodenal injury are not fully understood. Aspirin induces the release of reactive oxygen metabolites in animal models, which may contribute to mucosal injury. AIMS:To investigate the effects of aspirin administered with placebo or antioxidants on gastric mucosal react...

journal_title：Gut

authors： McAlindon ME,Muller AF,Filipowicz B,Hawkey CJ

更新日期：1996-04-01 00:00:00

abstract：:This paper reports the association between severe, prolonged, watery diarrhoea and islet cell tumours of the pancreas. There appear to be significant differences between patients with these symptoms and those with the classical Zollinger-Ellison syndrome. ...

journal_title：Gut

authors： TELLING M,SMIDDY FG

更新日期：1961-03-01 00:00:00

abstract：:Both hog gastrin and synthetic gastrin stimulate the cardiac sphincter to increase tone and augment the resistance to reflux. Endogenous gastrin has a similar effect, and gastrin also stimulates the secretion of acid which has also been found to increase the resistance of the sphincter, but the effect of gastrin appea...

journal_title：Gut

authors： Giles GR,Mason MC,Humphries C,Clark CG

更新日期：1969-09-01 00:00:00

abstract：BACKGROUND AND AIMS:A previous study suggested that the presence of myenteric plexitis in the proximal resection margins could be predictive of early endoscopic recurrence after ileocolonic or ileal resection for Crohn's disease (CD). The aim of the present study was to assess the predictive value of plexitis for early...

journal_title：Gut

authors： Sokol H,Polin V,Lavergne-Slove A,Panis Y,Treton X,Dray X,Bouhnik Y,Valleur P,Marteau P

更新日期：2009-09-01 00:00:00

abstract：:This presentation describes interim findings in a series of 319 patients referred from 41 hospitals on the basis of histopathological findings of 'early gastric cancer', 'dysplasia', or 'worrying mucosal appearances'. Data were recorded using a predefined proforma, and histopathological material circulated amongst a '...

journal_title：Gut

authors： de Dombal FT,Price AB,Thompson H,Williams GT,Morgan AG,Softley A,Clamp SE,Unwin BJ

更新日期：1990-01-01 00:00:00

abstract：:Ranitidine bismuth citrate was compared with an equipotent dose of ranitidine, to determine whether the former, by an anti-Helicobacter pylori activity, would counteract the rise of gastrin resulting from ranitidine's gastric acid antisecretory activity. Twenty four men with duodenal ulcers were studied before and on ...

journal_title：Gut

authors： Fraser AG,Lam WM,Luk YW,Sercombe J,Sawyerr AM,Hudson M,Samloff IM,Pounder RE

更新日期：1993-03-01 00:00:00

abstract：:The prevalence of deoxyribonucleic acid (DNA) aneuploidy in 297 samples from 38 patients with ulcerative colitis of varying duration was investigated by flow cytometry. In 12 patients colitis was complicated by the development of colorectal carcinoma: one had three synchronous carcinomas. Only four of 14 carcinomas we...

journal_title：Gut

authors： Fozard JB,Quirke P,Dixon MF,Giles GR,Bird CC

更新日期：1986-12-01 00:00:00

abstract：:Primary oesophageal involvement by lymphoma in two patients, one with Hodgkin's disease and one with non-Hodgkin's lymphoma is reported. In both, there were no manifestations of the disease outside the oesophagus, which is exceptionally rare. In the patient with non-Hodgkin's lymphoma, the oesophageal tumour was the f...

journal_title：Gut

authors： Taal BG,Van Heerde P,Somers R

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:Previous studies of anticipation in familial pancreatic cancer have been small and subject to ascertainment bias. Our aim was to determine evidence for anticipation in a large number of European families. PATIENTS AND METHODS:A total of 1223 individuals at risk from 106 families (264 affected individuals) w...

journal_title：Gut

authors： McFaul CD,Greenhalf W,Earl J,Howes N,Neoptolemos JP,Kress R,Sina-Frey M,Rieder H,Hahn S,Bartsch DK,European Registry of Hereditary Pancreatitis and Familial Pancreatic Cancer (EUROPAC).,German National Case Collection for Familial

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Recent reports have described a modulating influence of nitric oxide (NO) on intestinal mucosal permeability and have implicated a role for mast cells in this NO mediated process. AIMS:To assess further the contribution of mast cells to the mucosal permeability changes elicited by the NO synthase (NOS) inhi...

journal_title：Gut

authors： Komatsu S,Grisham MB,Russell JM,Granger DN

更新日期：1997-11-01 00:00:00

abstract：:Lactulose H2 breath tests are widely used for quantifying carbohydrate malabsorption, but the validity of the commonly used technique (interval sampling of H2 concentrations) has not been systematically investigated. In eight healthy adults we studied the reproducibility of the technique and the accuracy with which 5 ...

journal_title：Gut

authors： Rumessen JJ,Hamberg O,Gudmand-Høyer E

更新日期：1990-01-01 00:00:00

abstract：:A chronic colitis has been induced in rabbits having many of the histological features of human ulcerative colitis. Animals were first immunised with the common enterobacterial antigen of Kunin and haemagglutinating antibodies demonstrated in high titre. An immune complex colitis was then established by the injection ...

journal_title：Gut

authors： Mee AS,McLaughlin JE,Hodgson HJ,Jewell DP

更新日期：1979-01-01 00:00:00

abstract：OBJECTIVE:Nicotinamide phosphoribosyltransferase (NAMPT, also referred to as pre-B cell colony-enhancing factor or visfatin) is critically required for the maintenance of cellular nicotinamide adenine dinucleotide (NAD) supply catalysing the rate-limiting step of the NAD salvage pathway. NAMPT is strongly upregulated i...

journal_title：Gut

authors： Gerner RR,Klepsch V,Macheiner S,Arnhard K,Adolph TE,Grander C,Wieser V,Pfister A,Moser P,Hermann-Kleiter N,Baier G,Oberacher H,Tilg H,Moschen AR

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:Gluten-free diet (GFD) is the only management for coeliac disease (CD). Available methods to assess GFD compliance are insufficiently sensitive to detect occasional dietary transgressions that may cause gut mucosal damage. We aimed to develop a method to determine gluten intake and monitor GFD compliance in p...

journal_title：Gut

authors： Moreno ML,Cebolla Á,Muñoz-Suano A,Carrillo-Carrion C,Comino I,Pizarro Á,León F,Rodríguez-Herrera A,Sousa C

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Nitric oxide is a major neurotransmitter in non-adrenergic, non-cholinergic (NANC) pathways. NANC inhibitory innervation has been shown in human gall bladder muscle in vitro; the role of nitric oxide in human gall bladder emptying however is undefined. AIMS:To study the effect of glyceryl trinitrate, a nitr...

journal_title：Gut

authors： Greaves R,Miller J,O'Donnell L,McLean A,Farthing MJ

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:The potential of endoscopic mucosal resection (EMR) for treating flat dysplastic lesions in chronic ulcerative colitis (CUC) has not been addressed so far. Historically, such lesions were referred for colectomy. Furthermore, there are only limited data to support endoscopic resection of exophytic adenoma-lik...

journal_title：Gut

authors： Hurlstone DP,Sanders DS,Atkinson R,Hunter MD,McAlindon ME,Lobo AJ,Cross SS,Thomson M

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND AND AIMS:The detrimental impact of opioid agonist on the clinical management of inflammatory diseases remains elusive. Given the anti-inflammatory properties of the mu-opioid receptor (MOR) agonists at the intestinal barrier, we hypothesised that MOR activation might also dampen acute hepatic inflammation an...

journal_title：Gut

authors： Chakass D,Philippe D,Erdual E,Dharancy S,Malapel M,Dubuquoy C,Thuru X,Gay J,Gaveriaux-Ruff C,Dubus P,Mathurin P,Kieffer BL,Desreumaux P,Chamaillard M

更新日期：2007-07-01 00:00:00

abstract：:In order to investigate further the reported beneficial effect of deglycyrrhizinated liquorice in gastric ulcer, a trial with a double-blind, cross-over design was performed. The patients were treated during two consecutive periods of four weeks each with either liquorice extract during the first period and placebo du...

journal_title：Gut

authors： Engqvist A,von Feilitzen F,Pyk E,Reichard H

更新日期：1973-09-01 00:00:00

abstract：BACKGROUND:Different acid and peptic related gastroduodenal diseases are associated with both increased gastric secretion and Helicobacter pylori infection. Patients with H pylori associated gastritis or duodenal ulcer have increased serum pepsinogen levels which decrease after eradication. The mechanisms of H pylori i...

journal_title：Gut

authors： Lorente S,Doiz O,Trinidad Serrano M,Castillo J,Lanas A

更新日期：2002-01-01 00:00:00