Abstract:
:Effects of [Asu1,7]-eel calcitonin on gastric somatostatin and gastrin secretion were studied by using the isolated perfused rat stomach. [Asu1,7]-eel calcitonin (10(-9)--10(-7)M) caused a simultaneous dose-dependent increase of gastric somatostatin release and decrease of gastrin secretion, with a significant correlation between these two. The demonstration of calcitonin stimulation of gastric somatostatin release raises the possibility of somatostatin-mediated suppression of gastrin secretion by calcitonin.
journal_name
Gutjournal_title
Gutauthors
Chiba T,Taminato T,Kadowaki S,Goto Y,Mori K,Seino Y,Abe H,Chihara K,Matsukura S,Fujita T,Kondo Tdoi
10.1136/gut.21.2.94subject
Has Abstractpub_date
1980-02-01 00:00:00pages
94-7issue
2eissn
0017-5749issn
1468-3288journal_volume
21pub_type
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