Endotoxin, cytokines, and endotoxin binding proteins in obstructive jaundice and after preoperative biliary drainage.

abstract：BACKGROUND AND AIMS:Helicobacter pylori (H pylori) infection is a major risk factor in the development of distal gastric adenocarcinoma. Development of the invasive phenotype is associated with the phenomenon of epithelial:mesenchymal transition (EMT). Soluble heparin-binding epidermal growth factor (HB-EGF) has been i...

journal_title：Gut

authors： Yin Y,Grabowska AM,Clarke PA,Whelband E,Robinson K,Argent RH,Tobias A,Kumari R,Atherton JC,Watson SA

更新日期：2010-08-01 00:00:00

abstract：:The oral administration of loxtidine to mice at doses of 600, 250, and 50 mg/kg/day for 746 days produced carcinoid tumours of the gastric fundus. The fundic mucosa also showed marked atypical hyperplasia with changes in foveolar cells similar to those seen in early incomplete metaplasia. These effects may be related ...

journal_title：Gut

authors： Poynter D,Selway SA,Papworth SA,Riches SR

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:Serrated adenomas (SAs) of the colorectum combine architectural features of hyperplastic polyps and cytological features of classical adenomas. Molecular studies comparing SAs and classical adenomas suggest that each may be a distinct entity; in particular, it has been proposed that microsatellite instabilit...

journal_title：Gut

authors： Sawyer EJ,Cerar A,Hanby AM,Gorman P,Arends M,Talbot IC,Tomlinson IP

更新日期：2002-08-01 00:00:00

abstract：:Intestinal folate absorption was assessed in six normal subjects and in four patients with coeliac sprue who were studied before and after treatment by dietary gluten exclusion. Comparisons were made of the luminal disappearance from the perfused jejunum of 3H-pteroylmonoglutamate and pteroyl 14C-glutamylhexaglutamate...

journal_title：Gut

authors： Halsted CH,Reisenauer AM,Shane B,Tamura T

更新日期：1978-10-01 00:00:00

abstract：:Pancreatic secretion of lipase and chymotrypsin in response to elemental diets and a crushed food homogenate was studied in normal subjects. The solutions were infused at constant flow rates at the ligament of Treitz with polyethylene glycol as a nonabsorbable marker. A triple lumen tube was used, enabling collection ...

journal_title：Gut

authors： Vison N,Hecketsweiler P,Butel J,Bernier JJ

更新日期：1978-03-01 00:00:00

abstract：:A method of in vivo calculation of liver volume using a gamma camera and a 1600 or 4096 channel analyser is described. Topographically, the maximum thickness giving the highest counts in matrix data in the right anterior oblique projection is measured as the maximum breadth in the right posterior oblique projection. T...

journal_title：Gut

authors： Fujii M,Mukai T,Yamamoto T,Wakisaka G

更新日期：1976-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Transforming growth factor beta (TGF-beta) is frequently involved in gastrointestinal carcinogenesis although its contribution to oesophageal adenocarcinoma (AC) and its precursor Barrett's oesophageal epithelium (BE) metaplasia are unclear. METHODS:Expression of TGF-beta signalling components was ...

journal_title：Gut

authors： Onwuegbusi BA,Aitchison A,Chin SF,Kranjac T,Mills I,Huang Y,Lao-Sirieix P,Caldas C,Fitzgerald RC

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVE:Pancreatic acinar cell maturation is dependent on the activity of the pancreas transcription factor 1 (PTF1) complex. Induction of pancreatitis leads to MAP kinase activation and transient suppression of the acinar differentiation programme. We investigated the role of MAP kinase-interacting kinase 1 (Mnk1) i...

journal_title：Gut

authors： Cendrowski J,Lobo VJ,Sendler M,Salas A,Kühn JP,Molero X,Fukunaga R,Mayerle J,Lerch MM,Real FX

更新日期：2015-06-01 00:00:00

abstract：:To determine the significance of the endoscopic classification of gastritis proposed by a working party at the World Congress of Gastroenterology in Sydney 1990, 167 patients undergoing upper alimentary endoscopy were prospectively assessed by comprehensive endoscopic and histological methods. Ninety eight patients ha...

journal_title：Gut

authors： Khakoo SI,Lobo AJ,Shepherd NA,Wilkinson SP

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:Bovine immunoglobulin concentrate (BIC)-Clostridium difficile is prepared from the colostrum of cows immunised against C difficile toxins and contains high concentrations of neutralising IgG antitoxin. AIMS:To determine the proportion of BIC-C difficile which survives passage through the human stomach and s...

journal_title：Gut

authors： Warny M,Fatimi A,Bostwick EF,Laine DC,Lebel F,LaMont JT,Pothoulakis C,Kelly CP

更新日期：1999-02-01 00:00:00

abstract：:Carriers of beta amino acids and imino acids in the small intestine of rabbits and guinea pigs are chloride dependent, and a cotransport of chloride, sodium, and 2-methyl-aminoisobutyric acid has been shown. This study examines the chloride dependence of amino acid transport in the human small intestine. The steady st...

journal_title：Gut

authors： Munck LK

更新日期：1995-02-01 00:00:00

abstract：:The frequency of gastric Crohn's disease has been considered low. This study was undertaken to determine the prevalence of chronic gastritis and Helicobacter pylori infection in patients with Crohn's disease. Oesophagogastroduodenoscopy was performed on 62 consecutive patients suffering from ileocolonic Crohn's diseas...

journal_title：Gut

authors： Halme L,Kärkkäinen P,Rautelin H,Kosunen TU,Sipponen P

更新日期：1996-03-01 00:00:00

abstract：BACKGROUNDS AND AIMS:Telomerase is significantly reactivated in hepatitis B virus (HBV)-associated hepatocellular carcinoma (HCC). Our previous studies showed that the transactivation unit of HBV surface (S) gene, preS2, could upregulate human telomerase reverse transcriptase (hTERT) expression and telomerase activity ...

journal_title：Gut

authors： Luan F,Liu H,Gao L,Liu J,Sun Z,Ju Y,Hou N,Guo C,Liang X,Zhang L,Sun W,Ma C

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:A high prevalence of osteoporosis is reported in Crohn's disease. The pathogenesis is not completely understood but is probably multifactorial. Longstanding Crohn's disease is associated with a deficiency of fat soluble vitamins, among them vitamin K. Vitamin K is a cofactor in the carboxylation of osteocalc...

journal_title：Gut

authors： Schoon EJ,Müller MC,Vermeer C,Schurgers LJ,Brummer RJ,Stockbrügger RW

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND/AIMS:By contrast with animal models, in most cases it is not possible to examine the systemic response in patients in the first hours after onset of acute pancreatitis. The aim was to determine whether endoscopic retrograde cholangiopancreaticography (ERP)-induced pancreatitis can be used as a human model fo...

journal_title：Gut

authors： Messmann H,Vogt W,Holstege A,Lock G,Heinisch A,von Fürstenberg A,Leser HG,Zirngibl H,Schölmerich J

更新日期：1997-01-01 00:00:00

abstract：:The faecal blood loss of six alcoholic subjects with normal gastric mucosa, six with superficial gastritis, and six with atrophic gastritis was studied before and during ingestion of 40% v/v ethanol using (51)Cr-tagged red blood cells. No significant change in faecal blood loss was observed in the normal mucosa and su...

journal_title：Gut

authors： Dinoso VP Jr,Meshkinpour H,Lorber SH

更新日期：1973-04-01 00:00:00

abstract：BACKGROUND AND AIMS:The colons of patients with pneumatosis cystoides coli produce excessive H2. Exposure to alkyl halides could explain this. Six consecutive patients who had pneumatosis cystoides coli while taking chloral hydrate (1-5+ g/day) are reported. Patients 2 and 3 were investigated after they had ceased chlo...

journal_title：Gut

authors： Florin TH

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND:Interleukin 8 (IL-8) has recently been proposed to have an important role in mediating the development of the systemic sequelae associated with severe acute pancreatitis. AIMS:To define the role of IL-8 in acute pancreatitis by neutralising its effects with a monoclonal anti-IL-8 antibody (WS-4), in a rabbi...

journal_title：Gut

authors： Osman MO,Kristensen JU,Jacobsen NO,Lausten SB,Deleuran B,Deleuran M,Gesser B,Matsushima K,Larsen CG,Jensen SL

更新日期：1998-08-01 00:00:00

abstract：:This paper describes four patients whose chief symptoms were steatorrhoea and loss of weight. Despite the absence of a history of abdominal pain investigations showed that these patients had chronic pancreatitis, which responded to medical treatment. The pathological findings in two of these cases and in six which cam...

journal_title：Gut

authors： GOULSTON SJ,GALLAGHER ND

更新日期：1962-09-01 00:00:00

abstract：:The gastric secretory response to insulin changes in many patients between ;immediate' tests, within two weeks of vagotomy, and ;delayed' tests, done at least six months later. Patients who develop recurrent duodenal ulceration after vagotomy and pyloroplasty show highly significant increases in peak and rise in conce...

journal_title：Gut

authors： Watkin DF,Duthie HL

更新日期：1971-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Helicobacter pylori infection and gastric atrophy are both risk factors for gastric cancer. We aimed to elucidate the natural history of gastric cancer development according to H pylori infection and gastric atrophy status. SUBJECTS AND METHODS:A total of 9293 participants in a mass health appraisa...

journal_title：Gut

authors： Watabe H,Mitsushima T,Yamaji Y,Okamoto M,Wada R,Kokubo T,Doi H,Yoshida H,Kawabe T,Omata M

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Hypersensitivity of gastric afferent pathways may play an aetiological role in symptoms of functional dyspepsia. AIMS:To determine whether patients with severe organic dyspepsia (associated with tissue irritation/injury) and those with functional dyspepsia (no detectable tissue irritation) differ in their p...

journal_title：Gut

authors： Mertz H,Fullerton S,Naliboff B,Mayer EA

更新日期：1998-06-01 00:00:00

abstract：OBJECTIVE:Assessment of disease extension and activity is crucial to guide treatment in Crohn's disease. The objective of the current cross-sectional study was to determine the accuracy of MR for this assessment. DESIGN:50 patients with clinically active (n = 35) or inactive (n = 15) Crohn's disease underwent ileocolo...

journal_title：Gut

authors： Rimola J,Rodriguez S,García-Bosch O,Ordás I,Ayala E,Aceituno M,Pellisé M,Ayuso C,Ricart E,Donoso L,Panés J

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Linkage data have now identified several inflammatory bowel disease (IBD) susceptibility loci but these data have not been consistently replicated in independent studies. One potential explanation for this is the possibility that patients enrolled in such studies may have been erroneously classified with res...

journal_title：Gut

authors： Silverberg MS,Daly MJ,Moskovitz DN,Rioux JD,McLeod RS,Cohen Z,Greenberg GR,Hudson TJ,Siminovitch KA,Steinhart AH

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND AND AIMS:In HFE associated hereditary haemochromatosis, the duodenal enterocyte behaves as if iron deficient and previous reports have shown increased duodenal expression of divalent metal transporter 1 (DMT1) and iron regulated gene 1 (Ireg1) in affected subjects. In those studies, many patients had undergo...

journal_title：Gut

authors： Stuart KA,Anderson GJ,Frazer DM,Powell LW,McCullen M,Fletcher LM,Crawford DH

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:"Probiotic" bacteria are effective in treating some inflammatory bowel diseases. However which bacteria confer benefit and mechanisms of action remain poorly defined. Dendritic cells, which are pivotal in early bacterial recognition, tolerance induction, and shaping of T cell responses, may be central in med...

journal_title：Gut

authors： Hart AL,Lammers K,Brigidi P,Vitali B,Rizzello F,Gionchetti P,Campieri M,Kamm MA,Knight SC,Stagg AJ

更新日期：2004-11-01 00:00:00

abstract：:A retrospective survey was undertaken of 228 resected Meckel's diverticula to determine if there was any evidence of Campylobacter pylori infection in diverticula containing gastric mucosa. Among the 65 diverticula with gastric mucosa one was heavily infected with organisms having the morphological appearances of C py...

journal_title：Gut

authors： Morris A,Nicholson G,Zwi J,Vanderwee M

更新日期：1989-09-01 00:00:00

abstract：OBJECTIVE:Early detection and early treatment are of vital importance to the successful treatment of various cancers. The development of a novel screening method that is as economical and non-invasive as the faecal occult blood test (FOBT) for early detection of colorectal cancer (CRC) is needed. A study was undertaken...

journal_title：Gut

authors： Sonoda H,Kohnoe S,Yamazato T,Satoh Y,Morizono G,Shikata K,Morita M,Watanabe A,Morita M,Kakeji Y,Inoue F,Maehara Y

更新日期：2011-06-01 00:00:00

abstract：:To determine whether primary biliary cirrhosis differed in men and women we reviewed the presenting features and clinical course of 39 men and 191 women with primary biliary cirrhosis followed at this unit between 1970 and 1984. Age and severity of disease at time of diagnosis were similar in both groups. Pruritus was...

journal_title：Gut

authors： Lucey MR,Neuberger JM,Williams R

更新日期：1986-11-01 00:00:00

abstract：:Marked decreases in 24-hour Heidenhain pouch secretion, lasting from nine to 18 days, were observed in five mongrel bitches during periods of naturally occurring oestrus. Neither oophorectomy nor control celiotomy caused significant change in Heidenhain pouch secretion in bitches who were not experiencing oestrus. The...

journal_title：Gut

authors： Landor JH,Wild RA

更新日期：1970-10-01 00:00:00