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Adenocarcinoma of gastric cardia in the elderly: surgical problems and prognostic factors.

Abstract：

AIM:To analyze retrospectively, our results about patients who underwent surgical treatment for adenocarcinoma of the cardia in relation to age, in order to evaluate surgical problems and prognostic factors. METHODS:From January 1987 to March 2003, 140 patients with adenocarcinoma of the cardia underwent resection in the authors institution. They were divided into three groups with regard to age. Patients < 70 and > 60 year old (31) were excluded; we also excluded 18 out of 109 patients with poor general status or systemic metastases. So, we compared 51 elderly (> or = 70 year old) and 58 younger patients (> or = 60 year old). The treatment was esophagectomy for type I tumors, and extended gastrectomy and distal esophagectomy for type II and III lesions. RESULTS:Laparotomy was carried out in 91 patients (83.4%), 38 in the elderly (74.5%) and 53 in younger patients (91.3%, P<0.05). Primary resection was performed in 81 cases (89%) without significant differences between the two groups. Postoperative death was higher in the elderly (12.1%) than the other group (4.1%, P<0.05), while morbidity was similar in both groups. A curative resection (R0) was performed in 59 patients (72.8%), 69.6% in the elderly and 75% in the younger group (P>0.05). The overall 3- and 5-year survival rates were 26.7% and 17.8% respectively for the elderly and 40.7% and 35.1% respectively for younger patients (P=0.1544). Survival rates were significantly associated with R0 resection, pathological node-positive category and tumor differentiation in both groups. CONCLUSION:As the age of the general population increases, more elderly patients with gastric cardia cancer will be candidates for surgical resection. Age alone should not preclude surgical treatment in elderly patients with gastric cardia cancer and a tumor resection can be carried out safely. Certainly, we should take care in defining the surgical treatment in elderly patients, particularly as regarding the surgical approach; although the surgical approach does not influence the survival rate, the transhiatal way still remains the best one due, to the lower incidence of respiratory morbidity and thoracic pain.

journal_name

World J Gastroenterol

journal_title

World journal of gastroenterology

authors

Di Martino N,Izzo G,Cosenza A,Cerullo G,Torelli F,Brillantino A,del Genio A

doi

10.3748/wjg.v11.i33.5123

keywords:

subject

Has Abstract

pub_date

2005-09-07 00:00:00

pages

5123-8

issue

eissn

1007-9327

issn

2219-2840

journal_volume

pub_type

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Adenocarcinoma of gastric cardia in the elderly: surgical problems and prognostic factors.