Methanotrophic symbionts provide carbon for photosynthesis in peat bogs.

abstract：:Expansion of anthropogenic noise and night lighting across our planet1,2 is of increasing conservation concern3-6. Despite growing knowledge of physiological and behavioural responses to these stimuli from single-species and local-scale studies, whether these pollutants affect fitness is less clear, as is how and why ...

journal_title：Nature

authors： Senzaki M,Barber JR,Phillips JN,Carter NH,Cooper CB,Ditmer MA,Fristrup KM,McClure CJW,Mennitt DJ,Tyrrell LP,Vukomanovic J,Wilson AA,Francis CD

更新日期：2020-11-01 00:00:00

abstract：:A list of authors and their affiliations appears at the end of the paper New-particle formation is a major contributor to urban smog1,2, but how it occurs in cities is often puzzling3. If the growth rates of urban particles are similar to those found in cleaner environments (1-10 nanometres per hour), then existing un...

journal_title：Nature

authors： Wang M,Kong W,Marten R,He XC,Chen D,Pfeifer J,Heitto A,Kontkanen J,Dada L,Kürten A,Yli-Juuti T,Manninen HE,Amanatidis S,Amorim A,Baalbaki R,Baccarini A,Bell DM,Bertozzi B,Bräkling S,Brilke S,Murillo LC,Chiu R,

更新日期：2020-05-01 00:00:00

abstract：:Large parts of the Antarctic ice sheet lying on bedrock below sea level may be vulnerable to marine-ice-sheet instability (MISI), a self-sustaining retreat of the grounding line triggered by oceanic or atmospheric changes. There is growing evidence that MISI may be underway throughout the Amundsen Sea embayment (ASE),...

journal_title：Nature

authors： Ritz C,Edwards TL,Durand G,Payne AJ,Peyaud V,Hindmarsh RC

更新日期：2015-12-03 00:00:00

abstract：:During embryonic development, orderly patterns of gene expression eventually assign each cell in the embryo its particular fate. For the anteroposterior axis of the Drosophila embryo, the first step in this process depends on a spatial gradient of the maternal morphogen Bicoid (Bcd). Positional information of this gra...

journal_title：Nature

authors： Houchmandzadeh B,Wieschaus E,Leibler S

更新日期：2002-02-14 00:00:00

abstract：:In the initiation of translation in eukaryotes, binding of the small ribosomal subunit to the messenger RNA results from recognition of the 5' cap structure (m7GpppX) of the mRNA by the cap-binding complex eIF4F. eIF4F is itself a three-subunit complex comprising the cap-binding protein eIF4E, eIF4A, an ATP-dependent ...

journal_title：Nature

authors： Craig AW,Haghighat A,Yu AT,Sonenberg N

更新日期：1998-04-02 00:00:00

abstract：:A powerful way to discover key genes with causal roles in oncogenesis is to identify genomic regions that undergo frequent alteration in human cancers. Here we present high-resolution analyses of somatic copy-number alterations (SCNAs) from 3,131 cancer specimens, belonging largely to 26 histological types. We identif...

journal_title：Nature

authors： Beroukhim R,Mermel CH,Porter D,Wei G,Raychaudhuri S,Donovan J,Barretina J,Boehm JS,Dobson J,Urashima M,Mc Henry KT,Pinchback RM,Ligon AH,Cho YJ,Haery L,Greulich H,Reich M,Winckler W,Lawrence MS,Weir BA,Tanaka KE,

更新日期：2010-02-18 00:00:00

abstract：:Slower recovery from perturbations near a tipping point and its indirect signatures in fluctuation patterns have been suggested to foreshadow catastrophes in a wide variety of systems. Recent studies of populations in the field and in the laboratory have used time-series data to confirm some of the theoretically predi...

journal_title：Nature

authors： Dai L,Korolev KS,Gore J

更新日期：2013-04-18 00:00:00

abstract：:The selection and design of modern high-performance structural engineering materials is driven by optimizing combinations of mechanical properties such as strength, ductility, toughness, elasticity and requirements for predictable and graceful (non-catastrophic) failure in service. Highly processable bulk metallic gla...

journal_title：Nature

authors： Hofmann DC,Suh JY,Wiest A,Duan G,Lind ML,Demetriou MD,Johnson WL

更新日期：2008-02-28 00:00:00

abstract：:A short, 14-amino-acid segment called SP1, located in the Gag structural protein1, has a critical role during the formation of the HIV-1 virus particle. During virus assembly, the SP1 peptide and seven preceding residues fold into a six-helix bundle, which holds together the Gag hexamer and facilitates the formation o...

journal_title：Nature

authors： Dick RA,Zadrozny KK,Xu C,Schur FKM,Lyddon TD,Ricana CL,Wagner JM,Perilla JR,Ganser-Pornillos BK,Johnson MC,Pornillos O,Vogt VM

更新日期：2018-08-01 00:00:00

abstract：:MicroRNAs (miRNAs) are approximately 22-nucleotide endogenous RNAs that often repress the expression of complementary messenger RNAs. In animals, miRNAs derive from characteristic hairpins in primary transcripts through two sequential RNase III-mediated cleavages; Drosha cleaves near the base of the stem to liberate a...

journal_title：Nature

authors： Ruby JG,Jan CH,Bartel DP

更新日期：2007-07-05 00:00:00

abstract：:Spatial patterning is a ubiquitous feature of biological systems. Meiotic crossovers provide an interesting example, defined by the classic phenomenon of crossover interference. Here we identify a molecular pathway for interference by analysing crossover patterns in budding yeast. Topoisomerase II plays a central role...

journal_title：Nature

authors： Zhang L,Wang S,Yin S,Hong S,Kim KP,Kleckner N

更新日期：2014-07-31 00:00:00

abstract：:Neuronal circuits across several systems display remarkable plasticity to sensory input during postnatal development. Experience-dependent refinements are often restricted to well-defined critical periods in early life, but how these are established remains mostly unknown. A representative example is the loss of respo...

journal_title：Nature

authors： Fagiolini M,Hensch TK

更新日期：2000-03-09 00:00:00

abstract：:The folding of newly synthesized proteins to the native state is a major challenge within the crowded cellular environment, as non-productive interactions can lead to misfolding, aggregation and degradation1. Cells cope with this challenge by coupling synthesis with polypeptide folding and by using molecular chaperone...

journal_title：Nature

authors： Shiber A,Döring K,Friedrich U,Klann K,Merker D,Zedan M,Tippmann F,Kramer G,Bukau B

更新日期：2018-09-01 00:00:00

abstract：:The kinesin superfamily is a class of microtubule-based mechano-enzymes involved in intracellular transport and chromosome movements. Molecules that move towards either the plus end or the minus end of microtubules are represented within the family. The motor domains of these molecules exhibit considerable sequence ho...

journal_title：Nature

authors： Hoenger A,Sablin EP,Vale RD,Fletterick RJ,Milligan RA

更新日期：1995-07-20 00:00:00

abstract：:Synapse assembly requires trans-synaptic signals between the pre- and postsynapse, but our understanding of the essential organizational molecules involved in this process remains incomplete. Teneurin proteins are conserved, epidermal growth factor (EGF)-repeat-containing transmembrane proteins with large extracellula...

journal_title：Nature

authors： Mosca TJ,Hong W,Dani VS,Favaloro V,Luo L

更新日期：2012-03-18 00:00:00

abstract：:The preparation of synthetic molecules showing the remarkable efficiencies characteristic of natural biopolymer catalysts remains a formidable challenge for chemical biology. Although significant advances have been made in the understanding of protein structure and function, the de novo construction of such systems re...

journal_title：Nature

authors： Severin K,Lee DH,Kennan AJ,Ghadiri MR

更新日期：1997-10-16 00:00:00

abstract：:Insect eyes have an anti-reflective coating, owing to nanostructures on the corneal surface creating a gradient of refractive index between that of air and that of the lens material1,2. These nanocoatings have also been shown to provide anti-adhesive functionality3. The morphology of corneal nanocoatings are very dive...

journal_title：Nature

authors： Kryuchkov M,Bilousov O,Lehmann J,Fiebig M,Katanaev VL

更新日期：2020-09-01 00:00:00

abstract：:Heritable epigenetic polymorphisms, such as differential cytosine methylation, can underlie phenotypic variation. Moreover, wild strains of the plant Arabidopsis thaliana differ in many epialleles, and these can influence the expression of nearby genes. However, to understand their role in evolution, it is imperative ...

journal_title：Nature

authors： Becker C,Hagmann J,Müller J,Koenig D,Stegle O,Borgwardt K,Weigel D

更新日期：2011-09-20 00:00:00

abstract：:The assessment of uncertainties in global warming projections is often based on expert judgement, because a number of key variables in climate change are poorly quantified. In particular, the sensitivity of climate to changing greenhouse-gas concentrations in the atmosphere and the radiative forcing effects by aerosol...

journal_title：Nature

authors： Knutti R,Stocker TF,Joos F,Plattner GK

更新日期：2002-04-18 00:00:00

abstract：:Acute stress suppresses pain by activating brain pathways that engage opioid or non-opioid mechanisms. Here we show that an opioid-independent form of this phenomenon, termed stress-induced analgesia, is mediated by the release of endogenous marijuana-like (cannabinoid) compounds in the brain. Blockade of cannabinoid ...

journal_title：Nature

authors： Hohmann AG,Suplita RL,Bolton NM,Neely MH,Fegley D,Mangieri R,Krey JF,Walker JM,Holmes PV,Crystal JD,Duranti A,Tontini A,Mor M,Tarzia G,Piomelli D

更新日期：2005-06-23 00:00:00

abstract：:Evolutionary adaptation can be rapid and potentially help species counter stressful conditions or realize ecological opportunities arising from climate change. The challenges are to understand when evolution will occur and to identify potential evolutionary winners as well as losers, such as species lacking adaptive c...

journal_title：Nature

authors： Hoffmann AA,Sgrò CM

更新日期：2011-02-24 00:00:00

abstract：:Understanding the behaviour of the dielectric constant in ferroelectric thin films remains a challenging problem. These ferroelectric materials have high static dielectric constants, and so are important for their applications in high-storage-density capacitor structures such as dynamic random access memory (DRAM). Bu...

journal_title：Nature

authors： Sirenko AA,Bernhard C,Golnik A,Clark AM,Hao J,Si W,Xi XX

更新日期：2000-03-23 00:00:00

abstract：:RNA polymerase (Pol) II produces messenger RNA during transcription of protein-coding genes in all eukaryotic cells. The Pol II structure is known at high resolution from X-ray crystallography for two yeast species. Structural studies of mammalian Pol II, however, remain limited to low-resolution electron microscopy a...

journal_title：Nature

authors： Bernecky C,Herzog F,Baumeister W,Plitzko JM,Cramer P

更新日期：2016-01-28 00:00:00

abstract：:Long interspersed nuclear elements-1 (LINE-1 or L1s) are abundant retrotransposons that comprise approximately 20% of mammalian genomes. Active L1 retrotransposons can impact the genome in a variety of ways, creating insertions, deletions, new splice sites or gene expression fine-tuning. We have shown previously that ...

journal_title：Nature

authors： Muotri AR,Marchetto MC,Coufal NG,Oefner R,Yeo G,Nakashima K,Gage FH

更新日期：2010-11-18 00:00:00

abstract：:Rac signalling to actin -- a pathway that is thought to be mediated by the protein Scar/WAVE (WASP (Wiskott-Aldrich syndrome protein)-family verprolin homologous protein -- has a principal role in cell motility. In an analogous pathway, direct interaction of Cdc42 with the related protein N-WASP stimulates actin polym...

journal_title：Nature

authors： Eden S,Rohatgi R,Podtelejnikov AV,Mann M,Kirschner MW

更新日期：2002-08-15 00:00:00

abstract：:Mutants of cdc2+ can disrupt the dependency of S phase on completion of the previous mitosis. By changing the state of p34cdc2 it is possible to reprogramme a cell from entering mitosis to undergoing S phase. This leads to the proposal that the cell cycle can be considered a p34cdc2 cycle, and has implications for the...

journal_title：Nature

authors： Broek D,Bartlett R,Crawford K,Nurse P

更新日期：1991-01-31 00:00:00

abstract：:Aneuploidy, referring here to genome contents characterized by abnormal numbers of chromosomes, has been associated with developmental defects, cancer and adaptive evolution in experimental organisms. However, it remains unresolved how aneuploidy impacts gene expression and whether aneuploidy could directly bring abou...

journal_title：Nature

authors： Pavelka N,Rancati G,Zhu J,Bradford WD,Saraf A,Florens L,Sanderson BW,Hattem GL,Li R

更新日期：2010-11-11 00:00:00

abstract：:7SL RNA is an abundant cytoplasmic RNA which functions in protein secretion as a component of the signal recognition particle. Alu sequences are the most abundant family of human and rodent middle repetitive DNA sequences (reviewed in ref. 2). The primary structure of human 7SL RNA consists of an Alu sequence interrup...

journal_title：Nature

authors： Ullu E,Tschudi C

更新日期：1984-11-08 00:00:00

abstract：:Experimental and simulation studies show that small monomeric proteins fold in one kinetic step, which entails overcoming the free-energy barrier between the unfolded and the native protein through a transition state. Two models of transition state formation have been proposed: a 'nonspecific' one in which it depends ...

journal_title：Nature

authors： Shakhnovich E,Abkevich V,Ptitsyn O

更新日期：1996-01-04 00:00:00

abstract：:Barophilic bacteria inhabit the deep oceans, and the specific functional modifications and regulatory mechanisms which govern adaptation to hydrostatic pressure are beginning to be understood. For example, the rate of production of several proteins by some hydrothermal vent archaebacteria and the degree of saturation ...

journal_title：Nature

authors： Bartlett D,Wright M,Yayanos AA,Silverman M

更新日期：1989-11-30 00:00:00