Increased platelet Fc receptor expression in diabetes is limited to those with type 2 disease and low LDL cholesterol levels.

abstract：:Dyslipidemias are strongly linked to the development of atherosclerotic cardiovascular disease. Most dyslipidemias find their origin in the liver. In recent years, the differentiation of induced pluripotent stem cells (iPSCs) into hepatocyte-like cells has provided a versatile platform for the functional study of vari...

journal_title：Atherosclerosis

authors： Larsen LE,Smith MA,Abbey D,Korn A,Reeskamp LF,Hand NJ,Holleboom AG

更新日期：2020-06-01 00:00:00

abstract：:Plasma cholesterol was lower in spontaneously hypertensive rats (SHR), while plasma triglyceride and free fatty acid were increased in comparison with control normotensive Wistar-Kyoto (WK) rats. Correspondingly, [1-14C]-acetate incorporation into liver cholesterol was clearly decreased in SHR as compared with WK. As ...

journal_title：Atherosclerosis

authors： Iritani N,Fukuda E,Nara Y,Yamori Y

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:Acrolein is a dietary aldehyde that is present in high concentrations in alcoholic beverages and foods including cheese, donuts and coffee. It is also abundant in tobacco smoke, automobile exhaust and industrial waste and is generated in vivo during inflammation and oxidative stress. OBJECTIVES:The goal of ...

journal_title：Atherosclerosis

authors： Srivastava S,Sithu SD,Vladykovskaya E,Haberzettl P,Hoetker DJ,Siddiqui MA,Conklin DJ,D'Souza SE,Bhatnagar A

更新日期：2011-04-01 00:00:00

abstract：:Blood pressure elevation is frequently associated with elevated cholesterol, triglyceride or low density lipoprotein (LDL-C) or low high density lipoprotein (HDL-C). The relative importance of genetic and environmental factors in these associations is unclear. We examined the relative contribution of genetic and envir...

journal_title：Atherosclerosis

authors： Williams PD,Puddey IB,Martin NG,Beilin LJ

更新日期：1993-04-01 00:00:00

abstract：:Although the standard procedure for preparing extensively oxidized low-density lipoprotein (Ox-LDL) is to incubate it with 10muM CuSO(4) at 37 degrees C for 24h, it is not well known how important the degree of oxidation of LDL is for inducing cell signaling. Since Lox-1 (an Ox-LDL receptor) contributes to cell prolif...

journal_title：Atherosclerosis

authors： Tanigawa H,Miura S,Zhang B,Uehara Y,Matsuo Y,Fujino M,Sawamura T,Saku K

更新日期：2006-10-01 00:00:00

abstract：:A solid phase radioimmunoassay (RIA) has been developed for apolipoprotein B (apoB), a major constituent of very low density lipoprotein (VLDL) and low density lipoprotein (LDL) in man. Antisera were prepared against apoB in goats and rabbits, coupled to bromoacetyle cellulose, and the complex was incubated with [125I...

journal_title：Atherosclerosis

authors： Thompson GR,Birnbaumer ME,Levy RI,Gotto AM Jr

更新日期：1976-07-01 00:00:00

abstract：:Serum phospholipids were analyzed for their content of long-chained fatty acids together with other components of lipoproteins (total- and HDL-cholesterol, apolipoproteins A-I and B, triglycerides), in 60 coronary heart disease patients and 30 control individuals. Some of the individual variations in content of the va...

journal_title：Atherosclerosis

authors： Aursnes I,Smith P,Christiansen EN,Berg K

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND:Eosinophils have been involved in a wide spectrum of pro-inflammatory and pro-thrombotic conditions, with the development of cardiovascular complications in a significant proportion of hypereosinophilic patients. However, no study has so far evaluated the impact of eosinophils levels on periprocedural myocar...

journal_title：Atherosclerosis

authors： Verdoia M,Schaffer A,Barbieri L,Sinigaglia F,Marino P,Suryapranata H,De Luca G,Novara Atherosclerosis Study Group (NAS).

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVES:HIV+ patients are at increased risk of cardiovascular disease (CVD). Inflammation plays a role in adults, but has not yet been assessed in HIV+ children. We compared proinflammatory cytokines and adhesion molecules in HIV+ children versus healthy controls, and assessed their relationship to carotid intima-me...

journal_title：Atherosclerosis

authors： Ross AC,O'Riordan MA,Storer N,Dogra V,McComsey GA

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVE:Statins inhibit cholesterol synthesis but can upregulate cholesterol absorption, with higher doses producing larger effects. Ezetimibe inhibits cholesterol absorption but also upregulates synthesis. We tested whether ezetimibe added to on-going statin therapy would be most effective in lowering LDL-cholestero...

journal_title：Atherosclerosis

authors： Thongtang N,Lin J,Schaefer EJ,Lowe RS,Tomassini JE,Shah AK,Tershakovec AM

更新日期：2012-12-01 00:00:00

abstract：:The association between serum selenium concentration and a number of coronary heart disease risk factors is studied in 364 males from southern Italy participating in the Olivetti Heart Study. Selenium correlates positively and significantly with serum cholesterol (r = 0.120; P = 0.022), and this positive association p...

journal_title：Atherosclerosis

authors： Jossa F,Trevisan M,Krogh V,Farinaro E,Giumetti D,Fusco G,Galasso R,Panico S,Frascatore S,Mellone C

更新日期：1991-04-01 00:00:00

abstract：PURPOSE:To investigate whether atherosclerosis can be prevented by magnetically labeled endothelial progenitor cells (EPCs) in rabbits. MATERIALS AND METHODS:EPCs derived from rabbit periphery blood were labeled with a superparamagnetic iron oxide (SPIO) agent Fe(2)O(3)-poly-L-lysine (Fe(2)O(3)-PLL). Rabbit atheroscle...

journal_title：Atherosclerosis

authors： Ma ZL,Mai XL,Sun JH,Ju SH,Yang X,Ni Y,Teng GJ

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND AND AIMS:Abdominal aortic aneurysms (AAA) is a chronic inflammatory disease in which signal transducer and activator of transcription 3 (STAT3), and disintegrin and metalloproteinase 17 (ADAM17) play important roles. However, it remains unclear whether ursolic acid (UA), a natural pentacyclic triterpenoid ca...

journal_title：Atherosclerosis

authors： Zhai M,Guo J,Ma H,Shi W,Jou D,Yan D,Liu T,Tao J,Duan J,Wang Y,Li S,Lv J,Li C,Lin J,Zhang C,Lin L

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Divergent results have emerged in the past when relating single markers of inflammation to measures of vascular reactivity. The aim of the present study is to relate a wide range of inflammatory markers to vasoreactivity in both resistance and conductance arteries. METHODS:In the Prospective Investigation o...

journal_title：Atherosclerosis

authors： Lind L,Siegbahn A,Hulthe J,Elmgren A

更新日期：2008-07-01 00:00:00

abstract：:The PERTINENT study measured biomarkers of atherosclerosis and thrombosis in a stable coronary artery disease population from EUROPA receiving ACE inhibition with perindopril 8 mg/day or placebo. Biomarkers of inflammation, C-reactive protein (CRP), fibrinogen, and tumor necrosis factor-alpha (TNF-alpha), and a biomar...

journal_title：Atherosclerosis

authors： Ceconi C,Fox KM,Remme WJ,Simoons ML,Deckers JW,Bertrand M,Parrinello G,Kluft C,Blann A,Cokkinos D,Ferrari R

更新日期：2009-05-01 00:00:00

abstract：:Protein synthesis in smooth muscle cells from normal and atherosclerotic rabbit aortas was studied. Cultures of cells from the third passage were incubated with [3H]proline and the synthesis rates of collagen and total protein measured from the radioactivities incorporated into protein-bound hydroxyproline and proline...

journal_title：Atherosclerosis

authors： Pietilä K,Nikkari T

更新日期：1980-09-01 00:00:00

abstract：BACKGROUND AND AIMS:We aimed to evaluate a possible atheroprotective effect of saffron aqueous extract (SFE), and its potential anti-inflammatory mechanisms, in apoE knockout (ApoE-/-) mice. METHODS:Fifty male, ApoE-/- mice, fed a high-fat diet (HFD) for 12 weeks, were randomized into 5 groups: (1) baseline group, eut...

journal_title：Atherosclerosis

authors： Christodoulou E,Kadoglou NPE,Stasinopoulou M,Konstandi OA,Kenoutis C,Kakazanis ZI,Rizakou A,Kostomitsopoulos N,Valsami G

更新日期：2018-01-01 00:00:00

abstract：:The proband is a 50 year-old woman born from a consanguineous marriage. She has been suffering from angina pectoris since the age of 38 and underwent coronary bypass surgery for three-vessel disease at 48. The presence of low plasma levels of total cholesterol and high density lipoprotein (HDL) cholesterol (2.4 and 0....

journal_title：Atherosclerosis

authors： Bertolini S,Pisciotta L,Seri M,Cusano R,Cantafora A,Calabresi L,Franceschini G,Ravazzolo R,Calandra S

更新日期：2001-02-15 00:00:00

abstract：BACKGROUND:Recent failures of clinical trials promoting HDL-elevating therapies have prompted research groups to focus on its functional activity in disease. Endothelial effects of HDL can be measured with in vitro cell assays. The reproducibility and biological relevance of these assays have not been explored both in ...

journal_title：Atherosclerosis

authors： O'Neill F,McLoughlin E,Riwanto M,Manz J,Adler A,Sutill E,Khan T,Haywood R,Kay CW,D'Aiuto F,Charakida M,Landmesser U,Deanfield J

更新日期：2015-08-01 00:00:00

abstract：:Endurance exercise training is known to produce favorable changes in the metabolic profile including reduced plasma triglyceride (TG) and increased high-density lipoprotein (HDL) cholesterol concentrations. These metabolic improvements are likely to contribute to the reduced coronary heart disease (CHD) risk often obs...

journal_title：Atherosclerosis

authors： Bergeron J,Couillard C,Després JP,Gagnon J,Leon AS,Rao DC,Skinner JS,Wilmore JH,Bouchard C

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Familial hypercholesterolaemia (FH) is characterised by a high, but variable risk of premature coronary artery disease (CAD). Cardiac computed tomography angiography (CCTA) can be employed to assess subclinical coronary atherosclerosis. We investigated the features and distribution of coronary arter...

journal_title：Atherosclerosis

authors： Pang J,Abraham A,Vargas-García C,Bates TR,Chan DC,Hooper AJ,Bell DA,Burnett JR,Schultz CJ,Watts GF

更新日期：2020-04-01 00:00:00

abstract：:We investigated the association between the multiple metabolic risk factors and cardiovascular and overall mortality among Korean men, a population with a low prevalence of obesity. This prospective cohort study involved 682,597 Korean men, aged 30-69 years at baseline (1992), who were initially without cancer or debi...

journal_title：Atherosclerosis

authors： Park HS,Cho SI,Song YM,Sung J

更新日期：2006-07-01 00:00:00

abstract：AIMS:Transition metal ions have been implicated in atherosclerosis. The goal of this study was to investigate whether metal ion levels were higher in people with diabetes, in view of their increased risk of aggravated atherosclerosis. METHODS AND RESULTS:Absolute concentrations of iron, copper, zinc and calcium, and p...

journal_title：Atherosclerosis

authors： Stadler N,Heeneman S,Vöö S,Stanley N,Giles GI,Gang BP,Croft KD,Mori TA,Vacata V,Daemen MJ,Waltenberger J,Davies MJ

更新日期：2012-06-01 00:00:00

abstract：INTRODUCTION:Emerging data suggests that 3-dimensional (D) ultrasound (US) may provide us with a new tool for the identification of the vulnerable carotid plaque. METHODS:A systematic review of the PubMed, Scopus and Cochrane databases regarding the reproducibility and effectiveness of 3D US in evaluation of carotid p...

journal_title：Atherosclerosis

authors： Makris GC,Lavida A,Griffin M,Geroulakos G,Nicolaides AN

更新日期：2011-12-01 00:00:00

abstract：:Arterial specimens were obtained from 12 patients during arterial repair surgery and 3 patients during nephrectomy following a bolus injection of autologous radio-iodinated very low density lipoprotein (VLDL) up to 30 h before surgery. Radioactivity in apoprotein B (apo B) was determined in lipoprotein fractions isola...

journal_title：Atherosclerosis

authors： Nicoll A,Duffield R,Lewis B

更新日期：1981-05-01 00:00:00

abstract：BACKGROUND:Astaxanthin has been reported to improve dyslipidemia and metabolic syndrome in animals, but such effects in humans are not well known. METHODS:Placebo-controlled astaxanthin administration at doses of 0, 6, 12, 18 mg/day for 12 weeks was randomly allocated to 61 non-obese subjects with fasting serum trigly...

journal_title：Atherosclerosis

authors： Yoshida H,Yanai H,Ito K,Tomono Y,Koikeda T,Tsukahara H,Tada N

更新日期：2010-04-01 00:00:00

abstract：:It has been shown that triglyceride levels are one of the determinants of factor VII levels. In this study we have simultaneously evaluated, in a group of 102 healthy individuals, the different forms of factor VII, namely factor VII mass, factor VII coagulant activity, activated factor VII double-chain form and factor...

journal_title：Atherosclerosis

authors： Negri M,Arigliano PL,Talamini G,Carlini S,Manzato F,Bonadonna G

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:Moderate red wine has been shown to reduce cardiovascular disease (CVD) risk, however the effects on certain CVD risk factors are unclear. In this study we have investigated the effects of dealcoholised red wine (DRW) and full-complement red wine (RW) on several cardiovascular risk factors in mildly hypercho...

journal_title：Atherosclerosis

authors： Naissides M,Mamo JC,James AP,Pal S

更新日期：2006-04-01 00:00:00

abstract：:Chylomicron catabolism in the bloodstream consists of lipolysis by lipoprotein lipase and uptake of remnants by the liver. In rats, triglyceride-rich emulsions can mimic chylomicron metabolism. To further validate this model in man, the emulsion was injected intravenously into fasting and into subjects previously fed ...

journal_title：Atherosclerosis

authors： Maranhão RC,Feres MC,Martins MT,Mesquita CH,Toffoletto O,Vinagre CG,Gianinni SD,Pileggi F

更新日期：1996-09-27 00:00:00

abstract：:Atherosclerosis is a complex disease that gene and environment interaction influences the progression of atherosclerotic lesion development. Our laboratory used mice lacking both the low density lipoprotein (LDL) receptor and Apobec1 genes (LDLR-/-Apobec1-/-, designated LDb) to investigate gene-gene interaction and th...

journal_title：Atherosclerosis

authors： Dutta R,Singh U,Li TB,Fornage M,Teng BB

更新日期：2003-07-01 00:00:00