Abstract:
:C-Mpl and PRV-1 expression was measured in a cohort of 48 patients with essential thrombocythemia (ET). A retrospective analysis was conducted to asses whether the presence of one or both markers correlates with a higher risk of developing thromboembolic complications. In this cohort, PRV-1 overexpression was associated with a significantly increased risk of thrombosis, whereas decreased c-Mpl expression was not. The results of this retrospective analysis must now be corroborated in a large, prospective trial of newly diagnosed patients.
journal_name
Haematologicajournal_title
Haematologicaauthors
Goerttler PL,März E,Johansson PL,Andreasson B,Kutti J,Moliterno AR,Marchioli R,Spivak JL,Pahl HL,MPD Research Consortium.keywords:
subject
Has Abstractpub_date
2005-06-01 00:00:00pages
851-3issue
6eissn
0390-6078issn
1592-8721journal_volume
90pub_type
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