Hormone therapy use among postmenopausal French women before the publication of the Women's Health Initiative study: duration of use and factors associated with discontinuation.

Abstract:

OBJECTIVE:Compliance with recent recommendations concerning hormone therapy (HT) requires that we understand the reasons why women receiving HT continue or stop their treatment. Our aim was to estimate the duration of HT use and analyze factors associated with its discontinuation during the period before the publication of articles challenging the safety of HT. DESIGN:With data from 3 mail questionnaires--at inclusion (in 1990), 3 years, and 6 years--we estimated the cumulative treatment continuation rate by the actuarial method and used the Cox model to analyze the factors associated with discontinuation. SETTING:French women participating in the GAZEL cohort of employees of the French national power and electricity company (Electricité de France-Gaz de France). PATIENT(S):One thousand eighty-three postmenopausal women who were ever-HT users. INTERVENTION(S):None. MAIN OUTCOME MEASURE(S):Discontinuation of HT. RESULT(S):A total of 91.6% of women consulted gynecologists, and 88% continued treatment 5 years after they had begun it. Those reporting hot flashes as a reason for taking HT and those younger than 45 years old at menopause were less likely to stop HT, as were women reporting alcohol use. CONCLUSION(S):Our results demonstrate the importance of providing information to physicians, primarily gynecologists, to ensure appropriate treatment of symptoms for menopausal women, especially those younger than 45 years old, while bearing their long-term health in mind.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Ringa V,Varnoux N,Piault S,Bréart G

doi

10.1016/j.fertnstert.2004.12.040

keywords:

subject

Has Abstract

pub_date

2005-06-01 00:00:00

pages

1771-9

issue

6

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(05)00409-7

journal_volume

83

pub_type

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