Abstract：
OBJECTIVES:To test the hypothesis that fertility is reduced in baboons with endometriosis. DESIGN:Prospective controlled follow-up study. SETTING:Institute of Primate Research, Nairobi Kenya. SUBJECTS:Seventy-one baboons, including 34 controls (normal pelvis) and 37 animals with histologically proven endometriosis (16 spontaneous and 21 induced). Baboons with endometriosis had minimal (n = 9), mild (n = 14), moderate (n = 7), or severe (n = 7) disease. INTERVENTIONS:Seventy-one baboons were mated during 286 cycles. MAIN OUTCOME MEASURES:Cycle fecundity rate, cycle pregnancy rate, cycle abortion rate. RESULTS:Cycle pregnancy rate (excluding spontaneous abortions) was 15% (44/286) and was comparable between controls (19%, 20/104) and baboons with endometriosis (13%, 24/182). The cycle pregnancy rates were 24%, 10%, 7.5%, and 12.5% in animals with minimal, mild, moderate, and severe endometriosis, respectively. The cycle pregnancy rate was significantly lower in baboons with stage III-IV endometriosis (9%, 6/64) and with stage II disease (10%, 7/73) than in animals with stage I endometriosis (24%, 11/45) or in controls with a normal pelvis (19%). CONCLUSION:The normal cycle pregnancy rate in baboons with stage I endometriosis and the decreased cycle pregnancy rate in baboons with stage II and stage III-IV disease suggest that fertility decreases with the stage of endometriosis in baboons.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
D'Hooghe TM,Bambra CS,Raeymaekers BM,Riday AM,Suleman MA,Koninckx PRsubject
Has Abstractpub_date
1996-11-01 00:00:00pages
809-13issue
5eissn
0015-0282issn
1556-5653pii
S0015-0282(16)58641-5journal_volume
66pub_type
杂志文章abstract：:This study investigated the prevalence of Tyr204Phe and Val34Leu polymorphisms in two Brazilian ethnic groups (171 Caucasians and 27 Blacks, and 117 men and 81 women) and in patients with recurrent miscarriages (RM) (86 women: 53 Caucasians and 33 Blacks). Study groups were matched to control groups by race and age. T...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2004.04.052
更新日期：2004-11-01 00:00:00
abstract：:Immunocytochemical, biochemical, and histologic analysis of endometriotic lesions and endometria from rhesus macaques with endometriosis revealed several distinctions between ectopic and eutopic endometrium. In lesions, unlike endometrium, neither the mean percentages of estrogen receptor positive (ER+) cells nor the ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1988-02-01 00:00:00
abstract：OBJECTIVE:To compare in vitro fertilization (IVF) outcomes between fresh embryo transfer (ET) and frozen-thawed ET (the "freeze-all" policy), with fresh ET performed only in cases without progesterone (P) elevation. DESIGN:Prospective, observational, cohort study. SETTING:Private IVF center. PATIENT(S):A total of 53...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2015.01.045
更新日期：2015-05-01 00:00:00
abstract：OBJECTIVE:To compare blastocyst production, after IVF and ICSI, from sheep oocytes of various quality. Sham-injected oocytes and parthenogenetic activated oocyte groups were considered as control. DESIGN:Prospective experimental study. SETTING:University. ANIMAL(S):Three- to 6-month-old sheep. INTERVENTION(S):Oocyt...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2011.12.043
更新日期：2012-04-01 00:00:00
abstract：:Characterization of the implanting human fetus as an allograft prompted a field of research in reproductive immunology that continues to fascinate and perplex scientists. Paternal- or partner-derived alloantigens are present in the maternal host at multiple times during the reproductive process. They begin with exposu...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/j.fertnstert.2016.07.1073
更新日期：2016-09-01 00:00:00
abstract：OBJECTIVE:To investigate whether proteins secreted in urine differ between women with and without endometriosis. DESIGN:Laboratory study using human urine. SETTING:University-based laboratory. PATIENT(S):Women with and without endometriosis undergoing laparoscopy, hysteroscopy and curettage. INTERVENTION(S):Urine c...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2010.05.016
更新日期：2011-01-01 00:00:00
abstract：:Reportedly, gamete intrafallopian transfer and zygote intrafallopian transfer are successful methods in assisted conception. This pilot study describes the experiences and results of a recently developed technique of vaginal transcervical intrafallopian transfer. In a group of 38 women with unexplained infertility, oo...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)53704-2
更新日期：1990-08-01 00:00:00
abstract：OBJECTIVE:To elucidate reinitiation factors in human spermatozoa preserved in the electrolyte-free solution at 4 degrees C. SETTING:Andrology laboratory of our hospital. PATIENTS:Semen samples were obtained from patients attending our infertility clinic. INTERVENTIONS:Ejaculated sperm were centrifuged and washed usi...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)58341-1
更新日期：1996-06-01 00:00:00
abstract：OBJECTIVES:To assess the impact of a levonorgestrel-releasing implant contraceptive (Norplant; Wyeth-Ayerst Laboratories, Philadelphia, PA) on glucose metabolism. DESIGN:Prospective evaluation of insulin action and secretion in women under hyperglycemic hyperinsulinemic clamp conditions in the midfollicular phase befo...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章
doi：
更新日期：1995-04-01 00:00:00
abstract：OBJECTIVE:To report the case of a patient submitted to laparoscopic bowel resection in whom histology revealed endometriosis and schistosomiasis. DESIGN:Case report. SETTING:Multidisciplinary group practice and teaching hospital. PATIENT(S):A 31-year-old patient with pelvic pain. INTERVENTION(S):Laparoscopic bowel ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2005.08.068
更新日期：2006-04-01 00:00:00
abstract：OBJECTIVE:To study social and demographic differentiation of assisted reproduction technology (ART) use at the population level in the United States. DESIGN:Population-based study. SETTING:Not applicable. PATIENT(S):Women 15-49 years old in the American Community Survey and National Vital Statistics Birth Certificat...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2019.07.1323
更新日期：2019-12-01 00:00:00
abstract：:The effect of different concentrations of prolactin (0 to 60 ng) on the release of tetracycline from human spermatozoa labeled with 7-3H-tetracycline hydrochloride was studied. Prolactin significantly enhanced the release of bound tetracycline, indicating that prolactin may influence the processes associated with sper...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)43219-x
更新日期：1978-04-01 00:00:00
abstract：OBJECTIVE:To improve the sperm chromatin dispersion (SCD) test and develop it as a simple kit (Halosperm kit) for the accurate determination of sperm DNA fragmentation using conventional bright-field microscopy. DESIGN:Method development, comparison, and validation. SETTING:Medical genetics laboratory, academic biolo...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2004.11.089
更新日期：2005-10-01 00:00:00
abstract：:The morphologic characteristics of 85 cryptorchid and 63 contralateral (scrotal) testes showing histologic changes of puberty were studied. Spermatogenesis was not only delayed on the cryptorchid side but also hypocellular in all cases. The scrotal testes appeared hypocellular in 82.5% of the cases. Repetitive biopsie...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)46346-6
更新日期：1982-06-01 00:00:00
abstract：OBJECTIVE:To evaluate the association of an activating single-nucleotide polymorphism (SNP) at position -71 of the promoter of 17beta-hydroxysteroid dehydrogenase type 5 gene (-71A/G HSD17B5 SNP) and polycystic ovary syndrome (PCOS) in a well characterized cohort of caucasian PCOS women with biochemical hyperandrogenem...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2008.06.016
更新日期：2009-08-01 00:00:00
abstract：OBJECTIVE:To describe a case of bilateral internal jugular vein thrombosis complicating ovarian hyperstimulation syndrome (OHSS). DESIGN:Case report. SETTING:Internal medicine ward in a teaching hospital. PATIENT:A 28-year-old nulliparous woman undergoing IVF. INTERVENTION(S):Ultrasonographic Doppler of the neck ve...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(97)00459-7
更新日期：1998-01-01 00:00:00
abstract：OBJECTIVE:To investigate whether women who conceive after assisted reproductive technology (ART) are at higher risk for emergency peripartum hysterectomy. DESIGN:A case-control study using a prospectively maintained institutional database. SETTING:A tertiary referral university teaching maternity hospital. PATIENT(S...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2016.05.005
更新日期：2016-09-01 00:00:00
abstract：OBJECTIVE:To examine selection criteria for ovarian reserve screening. DESIGN:Retrospective study. PATIENTS:Two hundred nineteen women underwent testing for ovarian reserve for woman's age > 35 years, any age with unexplained infertility, one ovary, or a poor response to hMG. INTERVENTIONS:Clomiphene citrate challen...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)58386-1
更新日期：1996-07-01 00:00:00
abstract：OBJECTIVE:To characterize sperm parameters from thawed semen samples of men with different cancers who cryopreserved semen before oncologic therapy. DESIGN:Retrospective cohort study. SETTING:Tertiary academic medical center. PATIENT(S):1,010 semen samples collected between 1994 to 2010. INTERVENTION(S):None. MAIN...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2012.09.031
更新日期：2013-02-01 00:00:00
abstract：OBJECTIVE:To determine whether mutations in the gene for FSH beta are present, and possibly etiologic, in some patients with 46,XX premature ovarian failure (POF). DESIGN:DNA samples obtained from 18 study patients with POF and two menopausal fertile controls were studied by Southern blot analysis. DNA sequencing was ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)56286-4
更新日期：1993-11-01 00:00:00
abstract：OBJECTIVE:To evaluate the effects of a coculture with human endometrial cells on the function of spermatozoa from samples obtained from infertile couples. DESIGN:In a prospective study, human spermatozoa selected by swim-up from fresh samples were cultured on human endometrial feeder layers. Thereafter, their viabilit...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)56469-3
更新日期：1994-01-01 00:00:00
abstract：OBJECTIVE:To compare the performance of the Cook Sydney IVF (SIVF) embryo transfer (ET) catheter and the Edwards-Wallace (EW) ET catheter. DESIGN:Prospective randomized controlled clinical trial with an intention-to-treat analysis. SETTING:Two-center study. PATIENT(S):Four hundred consecutive women <40 years undergo...
journal_title：Fertility and sterility
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.fertnstert.2007.06.085
更新日期：2008-09-01 00:00:00
abstract：OBJECTIVE:To describe the molecular, cytogenetic, immunohistochemical, and endocrinologic characteristics of a young 46,XY female with persistent müllerian structures and germ cell tumors in dysgenetic gonads. DESIGN:Descriptive case study. SETTING:Mackay Memorial Hospital and National Yang-Ming University, Taipei, T...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(99)00169-7
更新日期：1999-07-01 00:00:00
abstract：:The level of the "Beaumont" protein present in serum was measured by a population of 223 black and 76 Caucasian women with different exposures to oral contraceptives (OCs). No differences were found in the values in nonusers, past users, current users, or new users of OCs. The values were higher in black nonusers and ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1983-10-01 00:00:00
abstract：OBJECTIVE:To examine the relationship between sperm chromatin defects, evaluated by the flow cytometric (FCM) sperm chromatin structure assay (SCSA), and the probability of a pregnancy in a menstrual cycle (fecundability). DESIGN:Follow-up study. SETTING:The Section of Toxicology and Biomedical Sciences, ENEA Casacci...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(99)00462-8
更新日期：2000-01-01 00:00:00
abstract：OBJECTIVE:To examine the prevalence of migraine in women with chronic pelvic pain with and without endometriosis. DESIGN:Prospective study of headache, pelvic pain, and quality of life before laparoscopic surgery for pelvic pain. Endometriosis was diagnosed pathologically. Headaches were classified as migraine or non-...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2010.11.037
更新日期：2011-03-01 00:00:00
abstract：OBJECTIVE:To develop a reliable sperm test that would predict pregnancy rate in assisted reproductive technologies. DESIGN:Blind prospective cohort study. SETTING:Tertiary-care, university hospital-affiliated IVF program. PATIENTS:One hundred nineteen sperm samples were obtained from 110 males from couples undergoin...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章
doi：10.1016/s0015-0282(16)58107-2
更新日期：1996-02-01 00:00:00
abstract：:Danazol and gestrinone are effective drugs in the treatment of endometriosis. Their mechanism of action remains uncertain, but may be related to their androgenic activity. The authors examined the effect of danazol on human endometrial cells cultured in vitro, its two major metabolites, ethisterone and 2 hydroxymethyl...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)59706-4
更新日期：1988-02-01 00:00:00
abstract：:Pieces of polyurethane, Teflon, silicone, and polyvinyl chloride were placed intraperitoneally to compare the histologic findings regarding intraperitoneal adhesion development in a rat model. The overall adhesion score differed significantly among the groups, the highest being in the Teflon group (mean 13.2), followe...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2004.10.012
更新日期：2005-02-01 00:00:00
abstract：OBJECTIVE:To evaluate the predictive value of seminal inhibin B and anti-Müllerian hormone (AMH) on the outcome of testicular sperm extraction (TESE) in patients with nonobstructive azoospermia. DESIGN:Prospective study. SETTING:Reproductive biology department. PATIENT(S):Forty-seven normospermic, 28 oligozoospermic...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2007.03.032
更新日期：2008-02-01 00:00:00
