C31 enhances voltage-gated calcium channel currents in undifferentiated PC12 cells.

abstract：:Cellular locations, axonal projections, and synaptic effects of inhibitory vestibulocollic (VC) neurons activated by the ampullary nerve of the posterior semicircular canal (PCN) were studied in anesthetized cats. The inhibitory VC neurons were identified by their monosynaptic responses to PCN stimulation and by their...

journal_title：Neuroscience letters

authors： Isu N,Sakuma A,Hiranuma K,Ichikawa T,Uchino Y

更新日期：1990-11-13 00:00:00

abstract：:Previous studies have shown that striatum and nucleus accumbens (NAc) are two different structures in mediating addictive drug-induced ascorbic acid (AA) release. In order to further characterize the different effects of drugs-induced AA release in the striatum and NAc, in the present study, we investigated the effect...

journal_title：Neuroscience letters

authors： Gu PF,Wu CF,Yang JY,Shang Y,Hou Y,Bi XL,Dai F

更新日期：2006-05-15 00:00:00

abstract：:Physical exercise-induced inflammation may be beneficial when exercise is regular but it may be harmful when exercise is intense and performed by unaccustomed individuals/rats. Molecular hydrogen (H2) has recently emerged as a powerful anti-inflammatory, antioxidant and anti-apoptotic molecule in a number of pathologi...

journal_title：Neuroscience letters

authors： Nogueira JE,de Deus JL,Amorim MR,Batalhão ME,Leão RM,Carnio EC,Branco LGS

更新日期：2020-01-10 00:00:00

abstract：:Serotonin transporter (5-HTT) is a key component of the serotonergic neurotransmitter system. Few studies have focused on polymorphisms of the serotonin transporter and antipsychotic response and, in particular, there have so far been no published studies on the association between the serotonin transporter and respon...

journal_title：Neuroscience letters

authors： Wang L,Yu L,He G,Zhang J,Zhang AP,Du J,Tang RQ,Zhao XZ,Ma J,Xuan JK,Xiao Y,Gu NF,Feng GY,Xu MQ,Xing QH,He L

更新日期：2007-02-27 00:00:00

abstract：:Kainic acid administration induces status epilepticus seizures in the rat which damage CA1 and CA3 hippocampal neurons. Rats made hypoglycemic prior to seizure had enhanced volumes of damage, when compared to normo- or hyperglycemic rats. The mild hypoglycemia was not in the range which, itself, typically produces hip...

journal_title：Neuroscience letters

authors： Sapolsky RM,Stein BA

更新日期：1989-02-13 00:00:00

abstract：:Rat pineal glands incubated in vitro with 10 or 100 microM norepinephrine (NE) released 51% and 415% more prostaglandin E2 (PGE2) to the medium than in the absence of NE. Phentolamine (10 microM) prevented fully the effect of NE at both concentrations, whereas propranolol failed to affect it significantly. After super...

journal_title：Neuroscience letters

authors： Ritta MN,Cardinali DP

更新日期：1982-08-31 00:00:00

abstract：:We developed a novel procedure for efficient mutagenesis of zebrafish using a DNA cross-linking agent 4,5',8-trimethylpsoralen (TMP), which is known to frequently induce small deletions in Escherichia coli and Caenorhabditis elegans. A specific-locus test and pilot screenings indicated that the TMP mutagenesis procedu...

journal_title：Neuroscience letters

authors： Ando H,Mishina M

更新日期：1998-03-13 00:00:00

abstract：:The nucleus of the basal optic root (nBOR) is involved in the generation of the optokinetic response. Previous studies showed that most nBOR neurons exhibit direction-selectivity in response to largefield motion. We investigated the responses of pigeon nBOR neurons to drifting sine wave gratings of varying spatial and...

journal_title：Neuroscience letters

authors： Crowder NA,W Wylie DR

更新日期：2001-05-25 00:00:00

abstract：:To determine whether mutations in the coding region of the alpha-synuclein gene are relevant in cases of multiple system atrophy (MSA), detailed nucleotide sequence analysis of the alpha-synuclein gene was performed using total RNA obtained from autopsied brain specimens of 11 pathologically confirmed cases of MSA. Th...

journal_title：Neuroscience letters

authors： Ozawa T,Takano H,Onodera O,Kobayashi H,Ikeuchi T,Koide R,Okuizumi K,Shimohata T,Wakabayashi K,Takahashi H,Tsuji S

更新日期：1999-07-30 00:00:00

abstract：:Orexins (OXs) stimulate sympathetic nerve activity to increase arterial pressure (AP) and heart rate (HR). We have previously reported that the OX(1)-receptor antagonist SB-334867 reversed the sympathomimetic actions of orexin A (OXA). In the present study we have investigated the role(s) of the orexinergic system in ...

journal_title：Neuroscience letters

authors： Hirota K,Kushikata T,Yoshida H,Kudo M,Kudo T

更新日期：2008-02-20 00:00:00

abstract：:The effects of bath-applied phorbol esters, protein kinase C (PKC) activators, and sphingosine, a PKC inhibitor, on membrane currents evoked by serotonin were studied in Xenopus oocytes injected with rat brain mRNA. The oscillatory Cl- current in response to bath-applied 50 nM serotonin was significantly depressed by ...

journal_title：Neuroscience letters

authors： Matsumoto M,Barnard EA

更新日期：1994-02-14 00:00:00

abstract：:A large dose of carbachol (5 micrograms/0.5 microliters) unilaterally microinjected into the rostral substantia nigra of rats induced stereotypy characterized by biting, gnawing and licking. A lower dose (0.5 micrograms/0.5 microliter) of the cholinomimetic potentiated normal food intake in satiated animals. Both the ...

journal_title：Neuroscience letters

authors： Taha EB,Redgrave P

更新日期：1980-12-01 00:00:00

abstract：:The input-output relation of a single neuron stands at the basis of every biologically oriented description of the brain. This report shows that the input-output relation of cultured cortical neurons is non-linearly tuned by the input frequency. Increasing the rate of stimulation results in the appearance of ordered t...

journal_title：Neuroscience letters

authors： Tal D,Jacobson E,Lyakhov V,Marom S

更新日期：2001-03-02 00:00:00

abstract：:Peripheral neuropathic pain is a common complication in the diabetic patients, and the underlying central mechanism remains unclear. Forebrain anterior cingulate cortex (ACC) is critically involved in the supraspinal perception of physical and affective components of noxious stimulus and pain modulation. Excitatory gl...

journal_title：Neuroscience letters

authors： Li W,Wang P,Li H

更新日期：2014-05-07 00:00:00

abstract：:The superoxide (O2.-) scavenging activity and the neuroprotective effects of pterin-6-aldehyde (P6A), a xanthine oxidase inhibitor, were examined and compared with those of alpha-phenyl-N-tert-butyl nitrone (PBN), a spin trapping agent. The scavenging activity of P6A was more potent than that of PBN by 150-fold in neu...

journal_title：Neuroscience letters

authors： Mori H,Arai T,Ishii H,Adachi T,Endo N,Makino K,Mori K

更新日期：1998-01-30 00:00:00

abstract：:The goal of the present study was to explore the relation between speed-accuracy trade-off phenomena and action kinematics in the case of pointing under isometric conditions. Increasing task difficulty resulted in a linear increase in movement time (as predicted by Fitts' law) and in systematic changes in the spatio-t...

journal_title：Neuroscience letters

authors： Billon M,Bootsma RJ,Mottet D

更新日期：2000-05-26 00:00:00

abstract：:Thermogenetics is a promising innovative neurostimulation technique, which enables robust activation of single neurons using thermosensitive cation channels and IR stimulation. The main advantage of IR stimulation compared to conventional visible light optogenetics is the depth of penetration (up to millimeters). Due ...

journal_title：Neuroscience letters

authors： Roshchin M,Ermakova YG,Lanin AA,Chebotarev AS,Kelmanson IV,Balaban PM,Zheltikov AM,Belousov VV,Nikitin ES

更新日期：2018-11-20 00:00:00

abstract：:The time-variant quadratic phase coupling (QPC) in trace alternant (TA) EEG patterns in healthy full-term neonates (quiet sleep) was investigated by means of time-variant bispectral analysis. The frequency plain 1-1.5 Hz <=> 3.5-4.5 Hz was used as the region-of-interest. QPC rhythms with a frequency of approximately 0...

journal_title：Neuroscience letters

authors： Schwab K,Putsche P,Eiselt M,Helbig M,Witte H

更新日期：2004-10-21 00:00:00

abstract：:Early craniectomy has shown to reduce infarction size in experimental large MCA infarction probably due to improved leptomeningeal perfusion. Based on the hypothesis that craniectomy may also be beneficial in smaller MCA infarction we evaluated the effects of craniectomy on infarction size in small thromboembolic cere...

journal_title：Neuroscience letters

authors： Engelhorn T,Heiland S,Schabitz WR,Schwab S,Busch E,Forsting M,Doerfler A

更新日期：2004-11-11 00:00:00

abstract：:The present study was aimed at investigating the role of gastrin in startle, startle habituation and prepulse inhibition (PPI). There were no significant differences between gastrin knockout mice and their wildtype controls in any of these baseline parameters. The disruption of PPI by treatment with 5 mg/kg of ampheta...

journal_title：Neuroscience letters

authors： van den Buuse M,van Driel IR,Samuelson LC,Pijnappel M,Martin S

更新日期：2005-01-20 00:00:00

abstract：:The existence of long-term effects of dark-rearing on visuo-motor coordination is still controversial. In this study 2 dark-reared (DR) cats were trained, after 5-6 years of recovery, to perform a reaching movement towards a stationary or a moving target. The accuracy, and the reaction and movement times were evaluate...

journal_title：Neuroscience letters

authors： Fabre-Thorpe M,Levesque F,Gary-Bobo E

更新日期：1990-10-16 00:00:00

abstract：:Melatonin is a tryptophan metabolite synthesized by the pineal gland. Recent research showed that melatonin has a protective effect in Alzheimer's disease (AD). However, its exact mechanism is still unclear. This study was designed to investigate the effects of long-term oral melatonin on spatial learning and memory, ...

journal_title：Neuroscience letters

authors： Sun C,Qiu X,Wang Y,Liu J,Li Q,Jiang H,Li S,Song C

更新日期：2020-09-14 00:00:00

abstract：:Alzheimer' disease is a neurodegenerative disorder characterized by the misfolding and aggregation of amyloid β (Aβ). This process is influenced through supply of cholesterol via apolipoproteins to neurons. In the present study, we used the transgenic Caenorhabditis elegans strain CL2006, which expresses Aβ1-42 under ...

journal_title：Neuroscience letters

authors： Regitz C,Wenzel U

更新日期：2014-07-25 00:00:00

abstract：:Prolactin (PRL) has been shown to be altered by psychotropic drugs, including antidepressant drugs (ADs). Many studies have focused on the response to antidepressant treatment (especially related to the serotonergic system) using the fenfluramine test (PRF), however some data suggest lack of correlation between PRF an...

journal_title：Neuroscience letters

authors： Faron-Górecka A,Kuśmider M,Szafran-Pilch K,Kolasa M,Żurawek D,Gruca P,Papp M,Solich J,Pabian P,Dziedzicka-Wasylewska M

更新日期：2017-04-24 00:00:00

abstract：:The present investigation describes for the first time leg lateral abduction performance during long-term microgravity exposure. Two astronauts took part in the experiments, starting 2 weeks into the mission and lasting for 5 months. Results on joint angles kinematics confirm previous investigations on parabolic fligh...

journal_title：Neuroscience letters

authors： Pedrocchi A,Baroni G,Mouchnino L,Ferrigno G,Pedotti A,Massion J

更新日期：2002-02-22 00:00:00

abstract：:Estrogens (E2) derived from ovaries and/or local de novo synthesis in the hippocampus profoundly regulate hippocampal structure and function, but the importance of local E2 versus ovarian E2 on hippocampal synaptic plasticity and spatial memory has not been well elucidated. The present study used ovariectomy (OVX) and...

journal_title：Neuroscience letters

authors： Liu M,Xing F,Bian C,Zhao Y,Zhao J,Liu Y,Zhang J

更新日期：2019-07-27 00:00:00

abstract：:Temperature effects on ocular serotonin N-acetyltransferase (NAT) kinetics characteristics from Rana perezi have been studied with respect to tryptamine and serotonin as substrates. Monoamine oxidase (MAO) activity does not interfere in NAT assay at acceptoramine concentrations used in NAT kinetics characterization fr...

journal_title：Neuroscience letters

authors： Alonso-Gómez AL,Alonso-Bedate M,Delgado MJ

更新日期：1993-05-28 00:00:00

abstract：:The aim of this study was to examine the ability of somatostatin receptor (sst(1)) to regulate the release of somatostatin in rat retina. Immunohistochemistry studies were performed to locate the somatostatin neurons, and radioligand binding to ascertain the presence of sst(1). The neuronal release of somatostatin was...

journal_title：Neuroscience letters

authors： Mastrodimou N,Thermos K

更新日期：2004-02-06 00:00:00

abstract：:Sinomenine, one of the alkaloids extracted from roots or stems of Sinomenium acutum, is documented to show antinociceptive action but the action mechanism is still unclear. The present study was aimed to investigate the effect of sinomenine on opioid mu-receptor (OMR). In Chinese Hamster Ovary (CHO) cell transfected w...

journal_title：Neuroscience letters

authors： Wang MH,Chang CK,Cheng JH,Wu HT,Li YX,Cheng JT

更新日期：2008-10-10 00:00:00

abstract：:P2X7 receptor is a ligand gated ion channel found peripheral macrophages and microglia in the nervous system. The current study investigated the relationship between the activated P2X7 and depression for the first time. Chrysophanol (Chr) was examined for its protective effects against depression targeting P2X7. Chr (...

journal_title：Neuroscience letters

authors： Zhang K,Liu J,You X,Kong P,Song Y,Cao L,Yang S,Wang W,Fu Q,Ma Z

更新日期：2016-02-02 00:00:00