Temporal variation of acute stress responses in sympathetic nervous and immune systems.

Abstract:

:Sympathetic nervous activity plays a prominent role in acute stress responses in the immune system, enhancement of innate immunity and suppression of specific immunity. The present study was conducted to examine the temporal characteristics of such immune responses to acute stress and to determine their association with sympathetic activity in detail. For this purpose, 15 female undergraduates engaged in a continuous mental arithmetic task for 14 min, and we collected their blood samples for immune indices (CD3+ T cells, CD4+ T cells, NK cells) each 3 min during the task and saliva samples before and after the task. Our results showed that the proportion of Natural Killer cells (NK cells) increased even 2 min after initiation of the task, whereas proportions of CD3+ and CD4+ lymphocytes decreased 8 min after initiation of the task. Moreover, we found significant correlations between cardiovascular activity and the variations of immune indices.

journal_name

Biol Psychol

journal_title

Biological psychology

authors

Kimura K,Isowa T,Ohira H,Murashima S

doi

10.1016/j.biopsycho.2004.12.006

keywords:

subject

Has Abstract

pub_date

2005-10-01 00:00:00

pages

131-9

issue

2

eissn

0301-0511

issn

1873-6246

pii

S0301-0511(05)00053-0

journal_volume

70

pub_type

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