Abstract:
:Sympathetic nervous activity plays a prominent role in acute stress responses in the immune system, enhancement of innate immunity and suppression of specific immunity. The present study was conducted to examine the temporal characteristics of such immune responses to acute stress and to determine their association with sympathetic activity in detail. For this purpose, 15 female undergraduates engaged in a continuous mental arithmetic task for 14 min, and we collected their blood samples for immune indices (CD3+ T cells, CD4+ T cells, NK cells) each 3 min during the task and saliva samples before and after the task. Our results showed that the proportion of Natural Killer cells (NK cells) increased even 2 min after initiation of the task, whereas proportions of CD3+ and CD4+ lymphocytes decreased 8 min after initiation of the task. Moreover, we found significant correlations between cardiovascular activity and the variations of immune indices.
journal_name
Biol Psycholjournal_title
Biological psychologyauthors
Kimura K,Isowa T,Ohira H,Murashima Sdoi
10.1016/j.biopsycho.2004.12.006keywords:
subject
Has Abstractpub_date
2005-10-01 00:00:00pages
131-9issue
2eissn
0301-0511issn
1873-6246pii
S0301-0511(05)00053-0journal_volume
70pub_type
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