An experimental model of ameboma in guinea pig.

Abstract:

:Among the wide variety of clinicopathological manifestations of intestinal amebiasis, amebomas occur rarely and their pathogenesis is not well understood. When cholesterol-fed, 2- to 4-week-old guinea pigs were infected intracecally with a virulent, monoaxenic strain of Entamoeba histolytica, gross and histologically characteristic amebomas developed in 85% of the animals by the 3rd day, in 94% by the 9th day, and in 96% by the 12th day postinfection, by which time most of them had died. Amebomas were confirmed by histopathology. Thus, a model of consistent production of amebomas was documented.

journal_name

Exp Parasitol

authors

Bhatti HS,Bhushnurmath S,Mahajan RC,Ganguly NK,Sehgal R

doi

10.1016/0014-4894(92)90151-y

keywords:

subject

Has Abstract

pub_date

1992-05-01 00:00:00

pages

283-9

issue

3

eissn

0014-4894

issn

1090-2449

pii

0014-4894(92)90151-Y

journal_volume

74

pub_type

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