Abstract:
:The role of salvage cryoablation of the prostate for patients with clinically localized prostate cancer that have failed radiotherapy to the prostate is reviewed with reference to alternatives including salvage radical prostatectomy and brachytherapy. The diagnosis and work-up of local recurrence/persistence of cancer in the prostate are reviewed and the patient selection criteria for salvage cryoablation is discussed. Technical aspects of the cryoablation procedure along with the outcome in terms of cancer control and treatment-related complications are detailed. The five-year biochemical disease-free rate is approximately 40%. The complication rate is acceptable. Salvage cryoablation definitely has a role in the management of localized prostate cancer treatment failure following radiotherapy, especially in older patients and those with some comorbidities.
journal_name
Technol Cancer Res Treatjournal_title
Technology in cancer research & treatmentauthors
Chin JL,Touma Ndoi
10.1177/153303460500400210keywords:
subject
Has Abstractpub_date
2005-04-01 00:00:00pages
211-6issue
2eissn
1533-0346issn
1533-0338pii
d=3022&c=4175&p=12907&do=detailjournal_volume
4pub_type
杂志文章,评审abstract:OBJECTIVE:The incidence of colorectal cancer is increasing every year, and autophagy may be related closely to the pathogenesis of colorectal cancer. Autophagy is a natural catabolic mechanism that allows the degradation of cellular components in eukaryotic cells. However, autophagy plays a dual role in tumorigenesis. ...
journal_title:Technology in cancer research & treatment
pub_type: 杂志文章
doi:10.1177/1533033820984177
更新日期:2020-01-01 00:00:00
abstract::This review addresses the epidemiology, historical reports, current issues, data and controversies involved in the management of brain metastases. The literature regarding surgery, whole brain radiation therapy, stereotactic radiosurgery or some combination of those treatments is discussed as well as issues of cost-ef...
journal_title:Technology in cancer research & treatment
pub_type: 杂志文章,评审
doi:10.1177/153303460300200205
更新日期:2003-04-01 00:00:00
abstract::The response of the tumor microvasculature to ionizing radiation can be modified to improve tumor control in preclinical mouse models of cancer. Recent studies have shown that a variety of cancer drugs can improve the response of cancers to radiotherapy. Protein tyrosine kinase inhibitors (TKIs) have been shown to enh...
journal_title:Technology in cancer research & treatment
pub_type: 杂志文章,评审
doi:10.1177/153303460500400614
更新日期:2005-12-01 00:00:00
abstract:PURPOSE:The study was aimed to compare online 6 degree-of-freedom image registrations of TrueBeam cone-beam computed tomography and BrainLab ExacTrac X-ray imaging systems for intracranial radiosurgery. METHODS:Phantom and patient studies were performed on a Varian TrueBeam STx linear accelerator (version 2.5), which ...
journal_title:Technology in cancer research & treatment
pub_type: 杂志文章
doi:10.1177/1533034616683069
更新日期:2017-06-01 00:00:00
abstract::Drug delivery to solid tumors is one of the most challenging aspects in cancer therapy. Whereas agents seem promising in the test tube, clinical trials often fail due to unfavorable pharmacokinetics, poor delivery, low local concentrations, and limited accumulation in the target cell. A major step forwards in the trea...
journal_title:Technology in cancer research & treatment
pub_type: 杂志文章,评审
doi:10.1177/153303460300200303
更新日期:2003-06-01 00:00:00
abstract::One of the most lethal carcinomas is pancreatic cancer. As standard treatment using chemotherapy and radiation has shown limited success, thermal regimens (cryotherapy or heat ablation) are emerging as viable alternatives. Although promising, our understanding of pancreatic cancer response to thermal ablation remains ...
journal_title:Technology in cancer research & treatment
pub_type: 杂志文章
doi:10.1177/1533034616655658
更新日期:2017-08-01 00:00:00
abstract:PURPOSE:To develop and evaluate an automatic intensity-modulated radiation therapy (IMRT) program for cervical cancer, including a Convolution Neural Network (CNN)-based prediction model and an automated optimization strategy. METHODS:A CNN deep learning model was trained to predict a patient-specify set of IMRT objec...
journal_title:Technology in cancer research & treatment
pub_type: 杂志文章
doi:10.1177/1533033820957002
更新日期:2020-01-01 00:00:00
abstract::A specific protein profile that accompanies neoplastic transformation in the premalignant airway epithelium could provide an opportunity for early diagnosis of lung cancer. The aim of this study was to screen and identify early candidate biomarkers of non-small cell lung cancer. Thirteen non-small cell lung cancer sam...
journal_title:Technology in cancer research & treatment
pub_type: 杂志文章
doi:10.1177/1533034615627391
更新日期:2017-02-01 00:00:00
abstract::Gastric cancer is one of the most commonly occurring cancers worldwide. Investigation of long noncoding RNAs is of increasing interest, particularly in relation to their contribution to progression and prognosis of gastric cancers; however, insufficient studies been performed investigating the part of long noncoding R...
journal_title:Technology in cancer research & treatment
pub_type: 杂志文章
doi:10.1177/1533033820930119
更新日期:2020-01-01 00:00:00
abstract::In cryosurgery it is crucial that the performance of cryoprobes is predictable and constant. In this study we tested the intra- and interneedle variation between 17-gauge cryoprobes in two homogeneous mediums. Also, a multiprobe setup was tested. Cryoprobe performance was defined as the time it takes one cryoprobe to ...
journal_title:Technology in cancer research & treatment
pub_type: 杂志文章
doi:10.1177/153303460800700406
更新日期:2008-08-01 00:00:00
abstract::The integrated use of optical technologies for patient monitoring is addressed in the framework of time-resolved treatment delivery for scanned ion beam therapy. A software application has been designed to provide the therapy control system (TCS) with a continuous geometrical feedback by processing the external surrog...
journal_title:Technology in cancer research & treatment
pub_type: 杂志文章
doi:10.7785/tcrtexpress.2013.600275
更新日期:2014-12-01 00:00:00
abstract::Volumetric modulated arc therapy (VMAT) has been adopted by many clinics for its higher delivery efficiency compared to conventional intensity modulated radiotherapy techniques. Currently, the quality assurance (QA) has remained a challenge in that no identical tests are available for accelerators from different vendo...
journal_title:Technology in cancer research & treatment
pub_type: 杂志文章
doi:10.1177/1533034614500419
更新日期:2015-08-01 00:00:00
abstract::The efficacy of photodynamic therapy for the treatment of a large number of skin diseases, in particular non-malignant skin cancer, has been reported by a number of studies. It has been demonstrated to be particularly beneficial for large or multiple lesions, especially where good cosmesis is required. However for PDT...
journal_title:Technology in cancer research & treatment
pub_type: 杂志文章,评审
doi:10.1177/153303460300200402
更新日期:2003-08-01 00:00:00
abstract::A fiber confocal back scattering micro-spectrometer (FCBS) was established, which combined fiber confocal microscopy with light scattering spectroscopy (LSS) for early diagnosis of the cancer cell at cellular level. An adherent monolayer human normal gastric epithelium line GES-1 and a carcinoma cell line NCI-N87 as w...
journal_title:Technology in cancer research & treatment
pub_type: 杂志文章
doi:10.7785/tcrt.2012.500222
更新日期:2011-10-01 00:00:00
abstract:PURPOSE:We investigated the dosimetric effect of intrafraction tumor motion in lung stereotactic body radiotherapy using the CyberKnife static tracking system. METHODS:Four-dimensional computed tomography scans of a dynamic thorax phantom were acquired. Two motion ranges, 3 collimator sizes, and 4 treatment starting p...
journal_title:Technology in cancer research & treatment
pub_type: 杂志文章
doi:10.1177/1533033819859448
更新日期:2019-01-01 00:00:00
abstract::We used a shifted-excitation Raman difference spectroscopy method for the ex vivo classification of resected and formalin-fixed breast tissue samples as normal (healthy) tissue, fibroadenoma, or invasive carcinoma. We analyzed 8 tissue samples containing invasive carcinoma that were surrounded by normal tissue and 3 t...
journal_title:Technology in cancer research & treatment
pub_type: 杂志文章
doi:10.1177/1533033818782532
更新日期:2018-01-01 00:00:00
abstract::Dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) is able to detect breast cancer with high sensitivity. Furthermore, this method provides functional information on tissue composition and vascularization. This study aims to identify the potential of DCE-MRI to predict distant metastasis in breast cancer p...
journal_title:Technology in cancer research & treatment
pub_type: 杂志文章
doi:10.7785/tcrt.2012.500266
更新日期:2012-12-01 00:00:00
abstract:PURPOSE:We recently developed a novel, open-source in vivo dosimetry that uses the electronic portal imaging device to detect dose delivery discrepancies. We applied our method on patients with rectal cancer treated on a belly board device. METHODS:In vivo dosimetry was performed on 10 patients with rectal cancer trea...
journal_title:Technology in cancer research & treatment
pub_type: 杂志文章
doi:10.1177/1533034617711519
更新日期:2017-12-01 00:00:00
abstract::Brachytherapy has the advantage of delivering a high dose to the tumor while sparing the surrounding normal tissues. With proper case selection and delivery technique, high-dose-rate (HDR) brachytherapy has great promise, because it eliminates radiation exposure, allows short treatment times, and can be performed on a...
journal_title:Technology in cancer research & treatment
pub_type: 杂志文章,评审
doi:10.1177/153303460400300305
更新日期:2004-06-01 00:00:00
abstract::The therapy of brain tumors has been limited by a lack of effective methods of drug delivery to the brain. Systemic administration is often associated with toxic side effects and ultimately fails to achieve therapeutic concentrations within a tumor. An attractive strategy that has gained importance in brain tumor ther...
journal_title:Technology in cancer research & treatment
pub_type: 杂志文章,评审
doi:10.1177/153303460500400409
更新日期:2005-08-01 00:00:00
abstract::This study aims to reduce the uncertainty about the photoneutron dose produced over a course of radiotherapy with high-energy photon beams and evaluate photoneutron contamination-based secondary malignancy risk for different treatment modalities. Dosimetric measurements were taken in Philips SL25/75, Elekta Synergy Pl...
journal_title:Technology in cancer research & treatment
pub_type: 杂志文章
doi:10.1177/1533034615592106
更新日期:2016-08-01 00:00:00
abstract:INTRODUCTION:Rectal cancer ranks as the eighth in cancer-related morbidity and the tenth in the cancer-related mortality. A few studies have explored several biomarkers for colorectal cancer. However, there is still a great need for us to excavate novel biomarkers with effective and efficient diagnostic and prognostic ...
journal_title:Technology in cancer research & treatment
pub_type: 杂志文章
doi:10.1177/1533033820973270
更新日期:2020-01-01 00:00:00
abstract::The PIN diode developed by Bhabha Atomic Research Centre (BARC) was modified for its use as a dosimeter in radiation therapy. For this purpose the diode was mounted on a printed circuit board (PCB) and provided with necessary connections so that its response against irradiation can be recorded by a standard radiothera...
journal_title:Technology in cancer research & treatment
pub_type: 杂志文章
doi:10.7785/tcrt.2012.500388
更新日期:2014-08-01 00:00:00
abstract::Breast cancer remains one of the leading causes of cancer-associated death in women. MiR-27a is highly expressed in breast cancer tissue. However, the underlying mechanisms that promote breast cancer progression are unknown. In this study, we investigated the regulatory mechanisms of miR-27a and its target glycogen Sy...
journal_title:Technology in cancer research & treatment
pub_type: 杂志文章
doi:10.1177/1533033820965576
更新日期:2020-01-01 00:00:00
abstract::In recent years, the imaging of drug-induced apoptosis has become one of the centers of interest in experimental and clinical research. In particular, the accurate monitoring of chemosensitivity as well as the early prediction of chemoresistance in response to various pro-apoptotic interventions are critical requireme...
journal_title:Technology in cancer research & treatment
pub_type: 杂志文章,评审
doi:10.1177/153303460400300103
更新日期:2004-02-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the mechanisms involved with miRNA-708 and its targeting of bone morphogenetic protein and activin membrane-bound inhibitor in cell proliferation, migration, and apoptosis in mice with melanoma via the Wnt and transforming growth factor β signaling pathways. METHODS:Sixt...
journal_title:Technology in cancer research & treatment
pub_type: 杂志文章
doi:10.1177/1533034618756784
更新日期:2018-01-01 00:00:00
abstract::The aim of this retrospective study is to evaluate our therapeutic results in patients with paranasal sinus (PNS) or nasal cavity (NC) malignancies treated with robotic stereotactic radiosurgery (SRS). Between August 2007 and October 2008, 27 patients with PNS or NC tumors were treated in our department using SRS. Med...
journal_title:Technology in cancer research & treatment
pub_type: 杂志文章
doi:10.7785/tcrtexpress.2013.600264
更新日期:2014-10-01 00:00:00
abstract::The therapeutic utility of the anthracycline antibiotic doxorubicin is limited due to its cardiotoxicity. Our aim was to investigate the efficacy of fullerenol C(60)(OH)(24) in preventing single, high-dose doxorubicin-induced cardiotoxicity in rats with malignant neoplasm. Experiment was performed on adult female Spra...
journal_title:Technology in cancer research & treatment
pub_type: 杂志文章
doi:10.1177/153303460800700102
更新日期:2008-02-01 00:00:00
abstract::The purpose of this study was to evaluate the feasibility and treatment plans of intensity-modulated radiation therapy using helical tomotherapy (HT) for brain metastases. Twenty-three patients with 1 to 4 brain metastases were treated with HT. In combination with whole-brain radiotherapy (simultaneous plans), metasta...
journal_title:Technology in cancer research & treatment
pub_type: 杂志文章
doi:10.1177/153303460800700602
更新日期:2008-12-01 00:00:00
abstract:PURPOSE:To evaluate a method for reducing metal artifacts, arising from dental fillings, on cone-beam computed tomography images. MATERIALS AND METHODS:A projection interpolation algorithm is applied to cone-beam computed tomography images containing metal artifacts from dental fillings. This technique involves identi...
journal_title:Technology in cancer research & treatment
pub_type: 杂志文章
doi:10.1177/1533034615618319
更新日期:2016-12-01 00:00:00