Therapeutic maturation of endometrium in in vitro fertilization and embryo transfer.

Abstract:

OBJECTIVE:To provide an up-to-date review of studies that have examined the relative role of endometrial development in in vitro fertilization (IVF) and embryo transfer (ET) treatment in relation to the treatment outcome. DATA IDENTIFICATION:The most important published studies and personal communications related to this topic have been identified through a computerized bibliographical search (MEDLINE). STUDY SELECTION:Studies that have evaluated the endometrial maturation in IVF and ET treatment with respect to different treatment protocols of ovarian stimulation. Clinical trials exploring the efficacy of various combinations of hormonal supplementation that aim to improve the endometrial environment and treatment outcome. Publications and personal communications reporting a variety of treatment protocols and drugs utilized for the creation of artificial endometrial cycles in IVF treatment employing donated eggs. RESULTS:Ovarian stimulation frequently adversely affects the process of endometrial maturation. Various kinds of hormonal supplementation, used in clomiphene citrate- and/or human menopausal gonadotropin (hMG)-stimulated cycles have not improved treatment outcome. Human chorionic gonadotropin or natural progesterone (P) supplementation administered after controlled ovarian stimulation with gonadotropin-releasing hormone and hMG effectively corrected the luteal phase defect and resulted in an improved conception rate. The endometrium of agonadal women is highly conducive to hormonal manipulation. All estrogen preparations used effectively promoted endometrial growth and proliferation. Natural P is superior to synthetic progestins for induction of receptive secretory endometrium. CONCLUSION:The development of adequately receptive endometrium is a major factor determining the outcome of IVF and ET treatment.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Ben-Nun I,Jaffe R,Fejgin MD,Beyth Y

doi

10.1016/s0015-0282(16)55008-0

keywords:

subject

Has Abstract

pub_date

1992-05-01 00:00:00

pages

953-62

issue

5

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(16)55008-0

journal_volume

57

pub_type

杂志文章,评审
  • Next-generation sequencing reveals differentially expressed small noncoding RNAs in uterine leiomyoma.

    abstract:OBJECTIVE:To determine the expression profile of small noncoding RNAs (sncRNAs) in leiomyoma, which has not been investigated to date. DESIGN:Laboratory-based investigation. SETTING:Academic center. PATIENT(S):Women undergoing hysterectomy for benign indications. INTERVENTION(S):Next-generation sequencing and scree...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2018.01.034

    authors: Chuang TD,Xie Y,Yan W,Khorram O

    更新日期:2018-05-01 00:00:00

  • Pseudoaneurysm of the uterine artery after laparoscopic myomectomy.

    abstract:OBJECTIVE:To describe a case of uterine pseudoaneurysm after laparoscopic myomectomy in a 36-year-old woman. DESIGN:Case report. SETTING:University hospital. PATIENT(S):A 36-year-old woman, 3 months after laparoscopic myomectomy, presenting with an intrauterine hypoechoic lesion measuring 5 cm in diameter. INTERVEN...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2008.09.019

    authors: Asai S,Asada H,Furuya M,Ishimoto H,Tanaka M,Yoshimura Y

    更新日期:2009-03-01 00:00:00

  • Growth hormone cotreatment for poor responders undergoing in vitro fertilization cycles: a systematic review and meta-analysis.

    abstract:OBJECTIVE:To evaluate the effectiveness of growth hormone (GH) supplementation in improving the in vitro fertilization (IVF) outcomes of poor responders. DESIGN:Systematic review and meta-analysis. SETTING:Not applicable. PATIENT(S):Poor ovarian responders undergoing conventional IVF or intracytoplasmic sperm inject...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2020.03.007

    authors: Cozzolino M,Cecchino GN,Troiano G,Romanelli C

    更新日期:2020-07-01 00:00:00

  • Laparoscopic management of hydrosalpinges before in vitro fertilization-embryo transfer: salpingectomy versus proximal tubal occlusion.

    abstract:OBJECTIVE:To compare ovarian response and IVF-ET cycle outcome in patients with hydrosalpinges managed by either laparoscopic salpingectomy or proximal tubal occlusion. DESIGN:Retrospective analysis. SETTING:Tertiary-care assisted reproductive technology program. PATIENT(S):One hundred four consecutive fresh IVF-ET ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(00)01742-8

    authors: Surrey ES,Schoolcraft WB

    更新日期:2001-03-01 00:00:00

  • Nitric oxide synthase isoforms expression in fibroblasts isolated from human normal peritoneum and adhesion tissues.

    abstract:OBJECTIVE:To determine the expression of nitric oxide synthases (NOSs) and their modulation by hypoxia in human peritoneal (NF) and adhesion fibroblasts (ADF). DESIGN:Prospective experimental study. SETTING:University medical center. PATIENT(S):Fibroblasts from peritoneum and adhesion tissues. INTERVENTION(S):Hypox...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2007.07.1313

    authors: Jiang ZL,Zhu X,Diamond MP,Abu-Soud HM,Saed GM

    更新日期:2008-09-01 00:00:00

  • Criteria for number of embryos to transfer: a committee opinion.

    abstract::Based on American Society for Reproductive Medicine (ASRM) and Society for Assisted Reproductive Technology data available for 2010, ASRM's guidelines for the number of embryos to be transferred in in vitro fertilization cycles have been further refined in continuing efforts to reduce the number of higher-order multip...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,实务指引

    doi:10.1016/j.fertnstert.2012.09.038

    authors: Practice Committee of the American Society for Reproductive Medicine and the Practice Committee of the Society for Assisted Reproductive Technology.

    更新日期:2013-01-01 00:00:00

  • Normal salivary progesterone levels throughout the ovarian cycle as determined by a direct enzyme immunoassay.

    abstract::This study, which is concerned with establishing clinically relevant corridors defining normal progesterone (P) levels in saliva, has addressed some of the shortcomings associated with previous equivalent studies (e.g., limited data, inadequately monitored ovulations, inadequately defined subjects). A sensitive, direc...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)60366-7

    authors: Finn MM,Gosling JP,Tallon DF,Madden AT,Meehan FP,Fottrell PF

    更新日期:1988-12-01 00:00:00

  • Early prediction of ovarian multifollicular response during ovulation induction in patients with polycystic ovary syndrome.

    abstract:OBJECTIVE:To examine the association between the midfollicular FSH-LH ratio and the number of follicles, and the multifollicular ovarian response to gonadotropin stimulation in patients with polycystic ovary syndrome (PCOS) with normal basal LH and FSH levels. SUBJECT(S):Eighteen patients who had an abandoned treatmen...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(97)80069-6

    authors: Farhi J,Jacobs HS

    更新日期:1997-03-01 00:00:00

  • Prospective randomized double-blind trial of 3 versus 6 months of nafarelin therapy for endometriosis associated pelvic pain.

    abstract:OBJECTIVES:To determine the effectiveness of a 3-month course of nafarelin and, furthermore, to determine the long-term efficacy in patients treated for 3 and 6 months with nafarelin for symptoms associated with endometriosis. DESIGN:Double-blind, prospective, multicenter, clinical trial. SETTING:Fifteen reproductive...

    journal_title:Fertility and sterility

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:

    authors: Hornstein MD,Yuzpe AA,Burry KA,Heinrichs LR,Buttram VL Jr,Orwoll ES

    更新日期:1995-05-01 00:00:00

  • Effects of pH on the migration of X and Y sperm.

    abstract::A study was undertaken to examine the influence of pH on the migration of X and Y sperm as observed in freshly ejaculated semen samples from human donors. These sperm were allowed to migrate into capillary tubes containing media of varying pH. Y-carrying sperm were i dentified using flourescent staining with quinacr...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)38224-3

    authors: Diasio RB,Glass RH

    更新日期:1971-05-01 00:00:00

  • Presence of the "Beaumont" protein in serum of oral contraceptive users.

    abstract::The level of the "Beaumont" protein present in serum was measured by a population of 223 black and 76 Caucasian women with different exposures to oral contraceptives (OCs). No differences were found in the values in nonusers, past users, current users, or new users of OCs. The values were higher in black nonusers and ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:

    authors: Collins DC,Bain RP,Coan P,Macpherson RF,Blumenstein B,Hall WD

    更新日期:1983-10-01 00:00:00

  • A frame shift mutation in the DNA-binding domain of the androgen receptor gene associated with complete androgen insensitivity, persistent müllerian structures, and germ cell tumors in dysgenetic gonads.

    abstract:OBJECTIVE:To describe the molecular, cytogenetic, immunohistochemical, and endocrinologic characteristics of a young 46,XY female with persistent müllerian structures and germ cell tumors in dysgenetic gonads. DESIGN:Descriptive case study. SETTING:Mackay Memorial Hospital and National Yang-Ming University, Taipei, T...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(99)00169-7

    authors: Chen CP,Chen SR,Wang TY,Wang W,Hwu YM

    更新日期:1999-07-01 00:00:00

  • Treatment-independent, treatment-associated, and pregnancies after additional therapy in a program of in vitro fertilization and embryo transfer.

    abstract::Although the technique of in vitro fertilization and embryo transfer (IVF-ET) was developed for couples with untreatable tubal factor infertility, IVF-ET is now being applied to women with other causes of infertility and normal pelvic anatomy. In an effort to determine the treatment-independent pregnancy rate, we retr...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)59114-6

    authors: Haney AF,Hughes CL Jr,Whitesides DB,Dodson WC

    更新日期:1987-04-01 00:00:00

  • The endocrinology of varicoceles.

    abstract::There is good evidence of an associated abnormality in testicular hormone production and spermatogenesis in some men with varicoceles. This abnormality can be demonstrated with dynamic tests of the hypothalamic-pituitary-testicular axis and by measuring seminal plasma androgen levels. A high proportion of oligozoosper...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,评审

    doi:10.1016/s0015-0282(16)59700-3

    authors: Hudson RW

    更新日期:1988-02-01 00:00:00

  • Cross-sectional analysis of the effects of age on the hormonal, metabolic, and ultrasonographic features and the prevalence of the different phenotypes of polycystic ovary syndrome.

    abstract:OBJECTIVE:To assess the effects of age on the hormonal, metabolic, and ultrasonographic features of polycystic ovary syndrome (PCOS). DESIGN:Observational study. SETTING:University department of obstetrics and gynecology. PATIENT(S):Patients with PCOS (n = 1,212) and healthy women (n = 254). INTERVENTION(S):None. ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2011.11.041

    authors: Panidis D,Tziomalos K,Macut D,Delkos D,Betsas G,Misichronis G,Katsikis I

    更新日期:2012-02-01 00:00:00

  • Specific isoforms of leucine-rich alpha2-glycoprotein detected in the proliferative endometrium of women undergoing assisted reproduction are associated with spontaneous pregnancy.

    abstract:OBJECTIVE:To examine differences in specific protein expression from the surface of the human endometrium with respect to eventual pregnancy in infertile women. DESIGN:Laboratory study. SETTING:University hospital. PATIENT(S):Thirty-one women presenting for investigation into infertility at an assisted reproductive ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2007.01.094

    authors: Gillott DJ,Al-Rumaih HM,Leung KY,Eldib A,Grudzinskas JG

    更新日期:2008-09-01 00:00:00

  • Lack of effect of short-term diazoxide administration on luteinizing hormone secretion in women with polycystic ovary syndrome.

    abstract:OBJECTIVE:To test the hypothesis that an acute reduction in circulating insulin affects LH secretion in women with polycystic ovary syndrome (PCOS). DESIGN:Prospective study in normal and PCOS women. SETTING:General Clinical Research Centers at the University of Virginia, the Medical College of Virginia, and the Mass...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2006.11.109

    authors: Evans WS,Taylor AE,Boyd DG,Johnson ML,Matt DW,Jimenez Y,Nestler JE

    更新日期:2007-07-01 00:00:00

  • Ovarian responses to menopausal gonadotropins in groups of patients with differing basal growth hormone levels.

    abstract:OBJECTIVE:To investigate the relationship between endogenous serum levels of human growth hormone (hGH) and ovarian response to human menopausal gonadotropins (hMG). DESIGN:Retrospective analysis of patient response to hMG. SETTING:Center for assisted reproductive technology. PATIENTS:Eighty women who had undergone ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)55133-4

    authors: Stone BA,Marrs RP

    更新日期:1992-07-01 00:00:00

  • Cryopreservation of human embryos by vitrification or slow freezing: a systematic review and meta-analysis.

    abstract:OBJECTIVE:To examine the literature systematically in order to identify prospective comparative trials answering the following question: Is vitrification of human embryos associated with a higher postthawing survival rate as compared with slow freezing? DESIGN:Systematic review and meta-analysis. SETTING:University-b...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.fertnstert.2007.06.010

    authors: Loutradi KE,Kolibianakis EM,Venetis CA,Papanikolaou EG,Pados G,Bontis I,Tarlatzis BC

    更新日期:2008-07-01 00:00:00

  • Robotic-assisted laparoscopic surgery: recent advances in urology.

    abstract::The aim of the present review is to summarize recent developments in the field of urologic robotic surgery. A nonsystematic literature review was performed to retrieve publications related to robotic surgery in urology and evidence-based critical analysis was conducted by focusing on the literature of the past 5 years...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,评审

    doi:10.1016/j.fertnstert.2014.05.033

    authors: Autorino R,Zargar H,Kaouk JH

    更新日期:2014-10-01 00:00:00

  • Adhesion prevention by solutions of sodium carboxymethylcellulose in the rat. II.

    abstract::In a rat model, sodium carboxymethylcellulose (SCMC) was compared with normal saline and 32% dextran 70 in the prevention of surgically induced intraperitoneal adhesions. The 32% dextran 70 was similar to normal saline in the initial prevention of adhesions, and both appeared less effective than SCMC. After lysis of t...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)47910-0

    authors: Elkins TE,Ling FW,Ahokas RA,Abdella TN,Homsey CA,Malinak LR

    更新日期:1984-06-01 00:00:00

  • World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonisation Project: I. Surgical phenotype data collection in endometriosis research.

    abstract:OBJECTIVE:To standardize the recording of surgical phenotypic information on endometriosis and related sample collections obtained at laparoscopy, allowing large-scale collaborative research into the condition. DESIGN:An international collaboration involving 34 clinical/academic centers and three industry collaborator...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,评审

    doi:10.1016/j.fertnstert.2014.07.709

    authors: Becker CM,Laufer MR,Stratton P,Hummelshoj L,Missmer SA,Zondervan KT,Adamson GD,WERF EPHect Working Group.

    更新日期:2014-11-01 00:00:00

  • Identification and treatment of men with phospholipase Cζ-defective spermatozoa.

    abstract:OBJECTIVE:To identify and treat the gamete responsible for complete fertilization failure with intracytoplasmic sperm injection (ICSI) using a newly proposed assisted gamete treatment (AGT). DESIGN:Prospective cohort study. SETTING:Center for reproductive medicine. PATIENT(S):One-hundred and fourteen couples with an...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2020.04.044

    authors: Cheung S,Xie P,Parrella A,Keating D,Rosenwaks Z,Palermo GD

    更新日期:2020-09-01 00:00:00

  • Effect of curcumin on aflatoxin-induced biochemical changes in testis of mice.

    abstract:OBJECTIVE:To investigate the effect of curcumin on aflatoxin-induced biochemical changes in testis of mice. DESIGN:Controlled research laboratory study. SETTING:Aflatoxin was obtained by growing Aspergillus parasiticus in SMKY liquid medium. Pure curcumin (97% purity) was purchased from Hi-Media Laboratories Pvt. Ltd...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2007.11.053

    authors: Verma RJ,Mathuria N

    更新日期:2009-02-01 00:00:00

  • Autoantibodies to markers of oxidative stress are elevated in women with endometriosis.

    abstract:OBJECTIVE:To measure autoantibodies that recognize oxidatively modified proteins in the sera of women with surgically proven endometriosis. DESIGN:Prospective study. SETTING:Tertiary care academic medical center. PATIENT(S):Women undergoing surgery for endometriosis or tubal ligation. INTERVENTION(S):None. MAIN OU...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(99)00145-4

    authors: Shanti A,Santanam N,Morales AJ,Parthasarathy S,Murphy AA

    更新日期:1999-06-01 00:00:00

  • The incidence of transient hyperprolactinemia in gonadotropin-stimulated cycles for in vitro fertilization and its effect on pregnancy outcome.

    abstract::The incidence of transient hyperprolactinemia and its impact on in vitro fertilization (IVF) were determined in 151 euprolactinemic women with tubal infertility undergoing an identical gonadotropin stimulation for IVF. Prolactin (PRL) levels were measured on the morning of cycle day 3, days of human chorionic gonadotr...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)60975-5

    authors: Hofmann GE,Denis AL,Scott RT,Muasher SJ

    更新日期:1989-10-01 00:00:00

  • Korean ginseng induces spermatogenesis in rats through the activation of cAMP-responsive element modulator (CREM).

    abstract::The effect of Korean ginseng (ginseng) on spermatogenesis and cAMP-responsive element modulator (CREM) in rat testes was evaluated using sperm analysis, reverse transcription polymerase chain reaction, and Western blot analysis. The ginseng-treated rats exhibited significantly increased sperm count and motility with e...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2006.12.014

    authors: Park WS,Shin DY,Kim DR,Yang WM,Chang MS,Park SK

    更新日期:2007-10-01 00:00:00

  • Lapatinib inhibits meiotic maturation of porcine oocyte-cumulus complexes cultured in vitro in gonadotropin-supplemented medium.

    abstract:OBJECTIVE:To determine whether inhibition of epidermal growth factor (EGF) receptor tyrosine kinase with lapatinib affects oocyte maturation, expression of the cumulus expansion-associated genes such as tumor necrosis factor alpha-induced protein 6 (TNFAIP6) and prostaglandin-endoperoxide synthase 2 (PTGS2), and synthe...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2012.12.040

    authors: Nagyova E,Nemcova L,Mlynarcikova A,Scsukova S,Kalous J

    更新日期:2013-05-01 00:00:00

  • A new mouse model for embryos with a hatching deficiency and its use to elucidate the mechanism of blastocyst hatching.

    abstract:OBJECTIVE:To develop an experimental model for embryos with a defect specific to hatching, with the purpose of clarifying the mammalian embryo hatching mechanism. DESIGN:A microneedle was inserted under the zona pellucida (ZP) of mouse embryos, and either 1/2 or 1/4 of the blastomeres were mechanically destroyed. The ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)55993-7

    authors: Gordon JW,Dapunt U

    更新日期:1993-06-01 00:00:00

  • Impact of right-left differences in ovarian morphology on the ultrasound diagnosis of polycystic ovary syndrome.

    abstract:OBJECTIVE:To assess right-left differences in ultrasonographic markers of ovarian morphology and determine the impact on the diagnosis of polycystic ovarian morphology (PCOM). DESIGN:A cross-sectional study of data collected from 2006 to 2018. SETTING:Academic clinical research centers. PATIENT(S):Women with polycys...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.fertnstert.2019.06.016

    authors: Jarrett BY,Vanden Brink H,Brooks ED,Hoeger KM,Spandorfer SD,Pierson RA,Chizen DR,Lujan ME

    更新日期:2019-11-01 00:00:00