Toxigenic status of Clostridium difficile in a large Spanish teaching hospital.

abstract：:The closely related Clostridium novyi and Clostridium botulinum types C and D are of current interest because of their association with serious infections in injecting drug users (C. novyi type A) and equine and feline dysautonomias (C. botulinum types C/D). The species are defined by the major toxins they produce: th...

journal_title：Journal of medical microbiology

authors： Heffron A,Poxton IR

更新日期：2007-02-01 00:00:00

abstract：:Francisella tularensis has been recognized as the causative agent of tularaemia for almost a century. Since its discovery in 1911, it has been shown to infect a wide range of hosts, including humans. As early as the 1920s it was suggested to be an intracellular pathogen, but it has proven to be an enigmatic organism, ...

journal_title：Journal of medical microbiology

authors： Oyston PCF

更新日期：2008-08-01 00:00:00

abstract：:Introduction.Serratia marcescens is a bacterial pathogen that causes ventilator-associated pneumonia and ocular infections. The FlhD and FlhC proteins complex to form a heteromeric transcription factor whose regulon, in S. marcescens, regulates genes for the production of flagellum, phospholipase A and the cytolysin S...

journal_title：Journal of medical microbiology

authors： Stella NA,Brothers KM,Shanks RMQ

更新日期：2020-12-10 00:00:00

abstract：:Transfer of an Hly plasmid determining production of alpha haemolysin to a non-haemolytic strain of Escherichia coli increased the virulence of the strain for mice. Injections of non-toxic amounts of alpha haemolysin, phenylhydrazine, haemoglobin, iron or manganese salts simulated the effect of the Hly plasmid by stim...

journal_title：Journal of medical microbiology

authors： Linggood MA,Ingram PL

更新日期：1982-02-01 00:00:00

abstract：:Coccidioidal pericarditis is a condition found in approximately 1-5% of patients infected by Coccidioides species. It is associated with widely diverse clinical symptoms. This paper reports a case of coccidioidal pericarditis diagnosed by an in-house Coccidioides posadasii antigen and confirmed with mycological and mo...

journal_title：Journal of medical microbiology

authors： Brilhante RSN,Cordeiro RA,Rocha MFG,Fechine MAB,Furtado FM,Nagao-Dias AT,Camargo ZP,Sidrim JJC

更新日期：2008-10-01 00:00:00

abstract：:The purpose of this study was to investigate the prevalence and epidemiology of the anaerobic intestinal spirochaete Brachyspira pilosicoli amongst Indonesians living in rural and urban settings on the island of Bali. Faecal samples (n = 992) were collected on two occasions, 4 months apart, from people living in four ...

journal_title：Journal of medical microbiology

authors： Margawani KR,Robertson ID,Brooke CJ,Hampson DJ

更新日期：2004-04-01 00:00:00

abstract：:Purpose. Acute bacterial meningitis continues to be a potentially life threatening condition. Hospital-acquired meningitis is rapidly increasing and adding an immense burden to the health system due to the emergence of multidrug resistance isolates. The purpose of this study is to find the antibiotic susceptibility pa...

journal_title：Journal of medical microbiology

authors： Raza MS,Das BK,Goyal V,Lodha R,Chaudhry R,Sood S,Gautam H,Sreenivas V,Nair D,Mohapatra S,Kapil A

更新日期：2019-11-01 00:00:00

abstract：:Pulsed-field gel electrophoresis typing was performed on a retrospective set of 129 Moraxella catarrhalis isolates obtained over a 20 month period from 70 children admitted to, or presenting at, the Erasmus University Medical Center, Rotterdam, The Netherlands. The mean age of the children (at the end of the study) wa...

journal_title：Journal of medical microbiology

authors： Hays JP,Eadie K,Verduin CM,Hazelzet J,Verbrugh H,van Belkum A

更新日期：2003-09-01 00:00:00

abstract：:The bactericidal action of non-immune whole blood on Proteus mirabilis was increased when the bacteria contained the R-plasmid RP1. This effect was due mainly to increased phagocytosis. Iron-depleted stationary-phase cells were more sensitive than carbon-depleted cells. The contribution of serum was usually negligible...

journal_title：Journal of medical microbiology

authors： Onaolapo JA,Klemperer RM

更新日期：1987-11-01 00:00:00

abstract：:The Pro-Pro-Glu (PPE) protein family of Mycobacterium tuberculosis includes 69 glycine-rich proteins with a conserved N-terminal domain. Their role in tuberculosis is unknown, but it has been speculated that they may have an important immunological significance. In this investigation, the immunogenicity of the ppe44 (...

journal_title：Journal of medical microbiology

authors： Bonanni D,Rindi L,Lari N,Garzelli C

更新日期：2005-05-01 00:00:00

abstract：:Acinetobacter junii is a rare human pathogen associated with bacteraemia in neonates and paediatric oncology patients. We present a case of A. junii causing bacteraemia in an adult transplant patient with leukaemia. The correct identification of Acinetobacter species can highlight the clinical significance of the diff...

journal_title：Journal of medical microbiology

authors： Cayô R,Yañez San Segundo L,Pérez Del Molino Bernal IC,García de la Fuente C,Bermúdez Rodríguez MA,Calvo J,Martínez-Martínez L

更新日期：2011-03-01 00:00:00

abstract：:Cytotoxin (CTX) production in 34 human and 22 animal strains of Campylobacter jejuni isolated in Japan and other countries was studied by three assay systems described previously. Furthermore, cholera-like enterotoxin production by these strains was tested by reversed passive latex agglutination (RPLA). CTX titres in ...

journal_title：Journal of medical microbiology

authors： Misawa N,Ohnishi T,Itoh K,Takahashi E

更新日期：1995-11-01 00:00:00

abstract：:A partially-purified neuraminidase from the mucinase complex of Vibrio cholerae was used to prepare a specific anti-neuraminidase antiserum in rabbits. When the neutralising potency of this serum against V. cholerae neuraminidase was assessed in conventional tests, the enzymic activity, as measured by thiobarbituric a...

journal_title：Journal of medical microbiology

authors： Stewart-Tull DE,Ollar RA

更新日期：1988-02-01 00:00:00

abstract：:The abilities of six strains of Salmonella typhimurium to associate with rabbit ileal mucosa have been measured in vitro. Two were "virulent" strains (TML and W118 which are invasive and inducers of fluid secretion in rabbit ileal loops); four were "avirulent" (LT7, M206 and SL1027 which are invasive but induce neglig...

journal_title：Journal of medical microbiology

authors： Worton KJ,Candy DC,Wallis TS,Clarke GJ,Osborne MP,Haddon SJ,Stephen J

更新日期：1989-08-01 00:00:00

abstract：:Corynebacterium jeikeium, a member of the non-diphtheria corynebacteria, has been rarely reported as being responsible for cardiovascular-device infection. Here, we report what is believed to be the first case of C. jeikeium pacemaker infection associated with the presence of proteinase-3 antineutrophil cytoplasmic an...

journal_title：Journal of medical microbiology

authors： Bechara C,Gousseff M,Passeron A,Podglajen I,Day N,Pouchot J,Lavergne T,Mainardi JL

更新日期：2011-02-01 00:00:00

abstract：:The susceptibility of chicks to enteritis caused by Campylobacter jejuni was studied. Three-day-old chicks did not develop enteritis after oral infection but chicks infected within 12 h of hatching developed gastroenteritis. The incubation period correlated with the inoculum size. Initially, infected chicks developed ...

journal_title：Journal of medical microbiology

authors： Welkos SL

更新日期：1984-10-01 00:00:00

abstract：:The purpose of the present study was to analyse mutations in the gyrA and gyrB genes of Mycobacterium tuberculosis and define the possible correlation between these mutations and resistance to levofloxacin (LVX), moxifloxacin (MFX) and gatifloxacin (GAT), based on their MICs. One hundred and forty-two M. tuberculosis ...

journal_title：Journal of medical microbiology

authors： Nosova EY,Bukatina AA,Isaeva YD,Makarova MV,Galkina KY,Moroz AM

更新日期：2013-01-01 00:00:00

abstract：:Leifsonia aquatica is an aquatic coryneform rod that is capable of forming biofilms in environmental water sources. It has rarely been associated with human infections and its pathogenicity and clinical significance are uncertain. We describe a case of catheter-related bloodstream infection in a haemodialysis patient....

journal_title：Journal of medical microbiology

authors： Porte L,Soto A,Andrighetti D,Dabanch J,Braun S,Saldivia A,Flores JC,Wozniak A,García P,Weitzel T

更新日期：2012-06-01 00:00:00

abstract：:Clostridium difficile-associated diarrhoea (CDAD) is the most common hospital-acquired diarrhoea, and is a major type of gastroenteritis infection in nursing homes and facilities for the elderly. In this study the antimicrobial activity of the two-component lantibiotic, lacticin 3,147, against a range of genetically d...

journal_title：Journal of medical microbiology

authors： Rea MC,Clayton E,O'Connor PM,Shanahan F,Kiely B,Ross RP,Hill C

更新日期：2007-07-01 00:00:00

abstract：:Bacteraemia in children is a potentially life-threatening condition. The objective of this study was to determine trends in the aetiology of bacteraemia in children aged 1 month-15 years in England and Wales by collecting data voluntarily reported by National Health Service hospital microbiology laboratories. Over the...

journal_title：Journal of medical microbiology

authors： Henderson KL,Johnson AP,Muller-Pebody B,Charlett A,Gilbert R,Sharland M

更新日期：2010-02-01 00:00:00

abstract：:Production of beta-lactamase by 15 strains of Haemophilus influenzae has been investigated. All the strains produce a constitutive beta-lactamase, which readily hydrolyses penicillin G, ampicillin, and cephaloridine. The beta-lactamase produced by these strains is indistinguishable from the type-IIIa enzyme commonly f...

journal_title：Journal of medical microbiology

authors： Sykes RB,Matthew M,O'Callaghan CH

更新日期：1975-08-01 00:00:00

abstract：:A new 1,8-naphthyridine quinolone antimicrobial, PD131628, was found to be as, or more active than ciprofloxacin or ofloxacin against Escherichia coli and considerably more active than the two 4-quinolone agents against staphylococci in terms of both MIC and OBC (the optimum bactericidal concentration, at which the ra...

journal_title：Journal of medical microbiology

authors： Lewin CS

更新日期：1992-05-01 00:00:00

abstract：:Fifty-five randomly selected Staphylococcus aureus strains were examined for fatty acid modifying enzyme (FAME) production. Of these, 20.4% did not elaborate the enzyme. Amongst the remaining strains, the lowest level produced in culture was 0.1 unit/10(9) cocci and the maximum was 2.01 U/10(9) cocci; the median level...

journal_title：Journal of medical microbiology

authors： Kapral FA,Smith S,Lal D

更新日期：1992-10-01 00:00:00

abstract：:We studied in vitro ceftaroline combinations against 61 meticillin-resistant Staphylococcus aureus isolates; 18 of them were also resistant to linezolid, using overlapping E-test method. Daptomycin-ceftaroline combination obtained lower fractional inhibitory concentration values, in comparison with those including van...

journal_title：Journal of medical microbiology

authors： García AB,Candel FJ,López L,Chiarella F,Viñuela-Prieto JM

更新日期：2016-10-01 00:00:00

abstract：:Acinetobacter baumannii is an emerging multidrug-resistant pathogen and very little information is available regarding its imipenem resistance in Latin American countries such as Bolivia. This study investigated the antimicrobial resistance profile of 46 clinical strains from different hospitals in Cochabamba, Bolivia...

journal_title：Journal of medical microbiology

authors： Sevillano E,Fernández E,Bustamante Z,Zabalaga S,Rosales I,Umaran A,Gallego L

更新日期：2012-01-01 00:00:00

abstract：:Introduction. Quantification of bacterial load in tissue homogenates in in vivo pharmacodynamic studies is cumbersome and time-consuming.Aim. We therefore developed a new method for quantifying bacterial load in tissue homogenates of animals treated with a β-lactam and β-lactamase inhibitor using growth curves.Methods...

journal_title：Journal of medical microbiology

authors： Georgiou PC,Mouton JW,Pournaras S,Meletiadis J

更新日期：2020-05-01 00:00:00

abstract：:Accurate susceptibility results on antibiotic-resistant bacteria are essential for proper treatment of infections. In this study, 100 metallo-β-lactamase (MBL)-producing strains and 95 isolates with Klebsiella pneumoniae carbapenemase (KPC) were tested for carbapenem susceptibility using two automated platforms, the P...

journal_title：Journal of medical microbiology

authors： Sun J,Xu Y,Yu Y,Ni Y

更新日期：2015-06-01 00:00:00

abstract：:Whole-cell-polypeptide profiles obtained by SDS-polyacrylamide gel electrophoresis (SDS-PAGE) were used in conjunction with the API-Staph technique to identify different strains of Staphylococcus aureus, S. epidermidis, S. saprophyticus and S. capitis. Complete concordance of results from both techniques was achieved ...

journal_title：Journal of medical microbiology

authors： Clink J,Pennington TH

更新日期：1987-02-01 00:00:00

abstract：:Introduction. Melioidosis, caused by Burkholderia pseudomallei, in endemic areas, poses a challenge for treating the diseased populations without accurate diagnosis, and the disease-specific biomarkers linked with the infection have yet to be reported. Due to the invasive nature of the causative agent, Burkholderia ps...

journal_title：Journal of medical microbiology

authors： Saikh KU,Ranji CM,Ulrich RG,Corea E,De Silva AD,Natesan M

更新日期：2020-10-01 00:00:00

abstract：PURPOSE:In this study, we aimed to investigate the genomic characteristics and evolution of pathogenicity islands of an enteropathogenic Escherichia coli (EPEC) strain, and to obtain a transcriptional profile of EPEC under different concentrations of ciprofloxacin using microarray analysis. METHODOLOGY:The complete EP...

journal_title：Journal of medical microbiology

authors： Chen Z,Cheng H,Pan W,Zheng J,Li D,Lin F,Yu Z,Deng Q

更新日期：2018-09-01 00:00:00