Abstract:
:The bactericidal action of non-immune whole blood on Proteus mirabilis was increased when the bacteria contained the R-plasmid RP1. This effect was due mainly to increased phagocytosis. Iron-depleted stationary-phase cells were more sensitive than carbon-depleted cells. The contribution of serum was usually negligible but was increased during a minor non-specific infection. Most plasmid-containing phenotypes were more sensitive than were those without plasmids but there were considerable differences between stationary and exponentially-growing cells. The R-plasmid-mediated increase in sensitivity to phagocytosis may be due in part to the presence of additional glycosylated proteins in the outer membrane.
journal_name
J Med Microbioljournal_title
Journal of medical microbiologyauthors
Onaolapo JA,Klemperer RMdoi
10.1099/00222615-24-3-233subject
Has Abstractpub_date
1987-11-01 00:00:00pages
233-40issue
3eissn
0022-2615issn
1473-5644journal_volume
24pub_type
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