Abstract:
:Keratoconus is a bilateral non-inflammatory corneal ectasia with an incidence of approximately 1 per 2000 in the general population. The etiology of keratoconus is multifactorial, although not completely understood. Several clinical observations suggest that thyroid gland dysfunction is associated with keratoconus pathophysiology. Pregnancy represents a major alteration in the maternal endocrinologic status characterized by modified function of the thyroid gland. We report on a 33-yr-old pregnant women suffering from keratoconus, who presented simultaneously with a remarkable deterioration of the disease during gestation and with thyroid gland dysfunction. Acute keratoconus in this patients coincided with the lowest plasma T4 level reached during pregnancy. During the third trimester of gestation, the keratoconus receded significantly. Here we provide direct evidence in support of a possible linkage between keratoconus and thyroid gland dysfunction, assumed by previous clinical observations. This case report is the first to suggest that changes in maternal thyroid hormone levels during pregnancy can aggravate the progression of keratoconus.
journal_name
J Endocrinol Investjournal_title
Journal of endocrinological investigationauthors
Gatzioufas Z,Thanos Sdoi
10.1007/BF03345600subject
Has Abstractpub_date
2008-03-01 00:00:00pages
262-6issue
3eissn
0391-4097issn
1720-8386pii
4517journal_volume
31pub_type
杂志文章abstract:PURPOSE:Female Sexual Dysfunction (FSD) is a still poorly studied and underdiagnosed condition. The aim of the study was to produce an improved version of FSFI-6 (6-Item Version of the Female Sexual Function Index), entitled Female Sexual Dysfunction Index-6 (FSDI-6), and to estimate its accuracy as a screening instrum...
journal_title:Journal of endocrinological investigation
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更新日期:2016-04-01 00:00:00
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journal_title:Journal of endocrinological investigation
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journal_title:Journal of endocrinological investigation
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更新日期:2012-01-01 00:00:00
abstract:: ...
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更新日期:2018-12-01 00:00:00
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journal_title:Journal of endocrinological investigation
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journal_title:Journal of endocrinological investigation
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journal_title:Journal of endocrinological investigation
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更新日期:2010-06-01 00:00:00
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更新日期:2017-03-01 00:00:00
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journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
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更新日期:1991-06-01 00:00:00
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pub_type: 临床试验,杂志文章
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pub_type: 杂志文章
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更新日期:1989-05-01 00:00:00
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journal_title:Journal of endocrinological investigation
pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2006-06-01 00:00:00
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更新日期:2015-08-01 00:00:00
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pub_type: 杂志文章
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更新日期:2018-12-01 00:00:00
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journal_title:Journal of endocrinological investigation
pub_type: 杂志文章,随机对照试验
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