Silver-Russell syndrome and its genetic origins.

abstract：:Antithyroid drugs may be proposed as the firstline therapy for hyperthyroidism due to Graves' disease since some patients undergo prolonged remission after drug withdrawal. On the other hand, some studies, though controversial, indicated that methimazole (MMI) has some immunomodulating activity. We retrospectively ana...

journal_title：Journal of endocrinological investigation

authors： Mazza E,Carlini M,Flecchia D,Blatto A,Zuccarini O,Gamba S,Beninati S,Messina M

更新日期：2008-10-01 00:00:00

abstract：:To determine the role of endogenous opioid peptides in regulating pulsatile luteinizing hormone (LH) release in the early follicular phase of the menstrual cycle of eumenorrheic women, we evaluated serum LH concentrations in blood collected every 10 min for 12 h in 27 women each studied during two menstrual cycles: (1...

journal_title：Journal of endocrinological investigation

authors： Evans WS,Weltman JY,Johnson ML,Weltman A,Veldhuis JD,Rogol AD

更新日期：1992-07-01 00:00:00

abstract：:We report the case of a 17-year-old girl presenting short stature (height 149 cm, below the 3rd percentile), obesity (weight 83.5 kg, body mass index 37 kg/m2) and secondary amenorrhea, in whom endocrinological evaluation disclosed an absolute lack of GH responsiveness to both suprapituitary challenges and repetitive ...

journal_title：Journal of endocrinological investigation

authors： Scacchi M,Alé G,Silvestri P,Cavagnini F

更新日期：1995-05-01 00:00:00

abstract：OBJECTIVE:Subcutaneous insulin absorption is one of the key factors affecting glycemic control in patients with diabetes mellitus under insulin therapy. Insulin-induced subcutaneous lipohypertrophy has been reported to impair insulin regular absorption and hence glycemic control. So far, lipohypertrophy diagnosis has o...

journal_title：Journal of endocrinological investigation

authors： Bertuzzi F,Meneghini E,Bruschi E,Luzi L,Nichelatti M,Epis O

更新日期：2017-10-01 00:00:00

abstract：:Benign thyroid nodules represent a very common disorder, the management of which is still controversial. The aim of the present work was to evaluate by ultrasound examination the volume changes of thyroid nodules in post-menopausal women presenting single palpable nodular goiter of recent onset (less than 6 months fro...

journal_title：Journal of endocrinological investigation

authors： Costante G,Crocetti U,Schifino E,Ludovico O,Capula C,Nicotera M,Arturi F,Filetti S

更新日期：2004-01-01 00:00:00

abstract：:We describe a unique case of spontaneous resolution of hyperparathyroidism in a lady with combined parathyroid adenoma and prolactinoma, raising the possibility of underlying multiple endocrine neoplasia (MEN) 1 syndrome. We also discuss the mechanism and natural history of such spontaneous remission. ...

journal_title：Journal of endocrinological investigation

authors： Baskar V,Kamalakannan D,Singh BM,Odum J

更新日期：2004-05-01 00:00:00

abstract：:EP1572 UMV1843 [Aib-DTrp-DgTrp-CHO]) is a new peptido-mimetic GH secretagogue (GHS) showing binding potency to the GHS-receptor in animal and human tissues similar to that of ghrelin and peptidyl GHS. EP1572 induces marked GH increase after s.c. administration in neonatal rats. Preliminary data in 2 normal young men s...

journal_title：Journal of endocrinological investigation

authors： Broglio F,Boutignon F,Benso A,Gottero C,Prodam F,Arvat E,Ghè C,Catapano F,Torsello A,Locatelli V,Muccioli G,Boeglin D,Guerlavais V,Fehrentz JA,Martinez J,Ghigo E,Deghenghi R

更新日期：2002-09-01 00:00:00

abstract：AIM:This 3-month study compared the effect on overall glycemic control of adding biphasic insulin aspart 30 (BIAsp30) and premixed human insulin 30/70 (BHI30) to metformin (met) in insulin-naïve, obese patients (30 males/20 females) with Type 2 diabetes (T2DM). MATERIAL/SUBJECTS: At baseline, patients had a mean age of...

journal_title：Journal of endocrinological investigation

authors： Velojic-Golubovic M,Mikic D,Pesic M,Dimic D,Radenkovic S,Antic S

更新日期：2009-01-01 00:00:00

abstract：PURPOSE:Testosterone replacement therapy (TRT) is recommended for the treatment of most cases of male hypogonadism. Transdermal testosterone (T) gels are commonly used in clinical practice; however, there is little evidence concerning how to monitor dosage to bring and maintain serum T levels in the normal physiologic ...

journal_title：Journal of endocrinological investigation

authors： Sansone A,Sansone M,Selleri R,Schiavo A,Gianfrilli D,Pozza C,Zitzmann M,Lenzi A,Romanelli F

更新日期：2019-12-01 00:00:00

abstract：:There is increasing evidence that androgen therapy in men may be effectively applied in several conditions to improve well being and health. Classical indications for androgen therapy in males are represented by primary or secondary hypogonadism, delayed puberty, aplastic anemia and that secondary to chronic renal fai...

journal_title：Journal of endocrinological investigation

authors： Gambineri A,Pasquali R

更新日期：2000-03-01 00:00:00

abstract：:Typical modifications of cardiovascular activity and water and salt homeostasis throughout female reproductive life are well known. Differences in plasma levels of calcitonin gene-related peptide (CGRP) and atrial natriuretic peptide (ANP) have been observed in conditions characterized by different estrogenic levels, ...

journal_title：Journal of endocrinological investigation

authors： Bernardi F,Valentini A,Margutti A,Santuz M,Degli Uberti EC,Petraglia F,Genazzani AR

更新日期：1998-04-01 00:00:00

abstract：:The status of the erythrocyte insulin receptor was investigated prior to and during storage at 4C in acid-citrate dextrose (ACD) solution. The receptors on cells that were obtained from both resting and exercised fasting subjects and stored for up to three days in ACD were unchanged as evaluated by both maximal specif...

journal_title：Journal of endocrinological investigation

authors： Robbins PA,Kwan C,Searle GL

更新日期：1983-08-01 00:00:00

abstract：:It has been shown that human calcitonin (hCT) is absorbed through the nasal mucosa when administered together with promoters like sodium glycocholate (SGC) or dihydrofusinate. The aim of this study was to compare the clinical and metabolic effect of intranasal (in) and intramuscular (im) hCT in patients with osteoporo...

journal_title：Journal of endocrinological investigation

authors： Pontiroli AE,Pajetta E,Calderara A,Alberetto M,Pozza G,Manganelli V,Resmini G,Tessari L,Maresca V

更新日期：1991-01-01 00:00:00

abstract：:Graves' disease (GD) is the most prevalent cause of thyrotoxicosis in children. Because spontaneous and lasting resolution of this condition occurs in only a minority of patients, most pediatric patients with GD will need radioactive iodine treatment (131I) or thyroidectomy. Whereas the medication propylthiouracil (PT...

journal_title：Journal of endocrinological investigation

authors： Rivkees SA

更新日期：2016-11-01 00:00:00

abstract：:Eleven patients with Paget's disease of bone, treated intermittently for 2-4 years with porcine calcitonin (pCT) and clinically resistant to pCT [no modifications of serum alkaline phosphatase (ALP) and urinary hydroxyproline ( uHOP ) during pCT administration] were treated with 0.5-0.25 mg/day of human calcitonin (hC...

journal_title：Journal of endocrinological investigation

authors： Lo Cascio V,Adami S,Galvanini G,Lazzaretto R,Ferrari M,Tartarotti D,Scuro LA

更新日期：1984-04-01 00:00:00

abstract：:The physiological pulsatile secretion of GH in humans might be important for the metabolic effects of GH. In the treatment of GH-deficient (GHD) patients, the most common regimen is a single sc injection at bedtime. It has not been completely established if this is the optimal mode of GH administration during long-ter...

journal_title：Journal of endocrinological investigation

authors： Höybye C,Rudling M

更新日期：2006-12-01 00:00:00

abstract：:Rats bearing mammosomatotropic tumors have raised insulin but lowered glucose concentrations. To determine if growth hormone (GH) secreted by these tumors causes insulin antagonism, pancreatic suppression tests utilizing infusions (per kg per min) of glucose (8 mg), insulin (200 ng) and somatostatin (1.4 micrograms) f...

journal_title：Journal of endocrinological investigation

authors： Davidson MB,Shen DC,Venkatesan N,Sladen G

更新日期：1987-12-01 00:00:00

abstract：PURPOSE:Interleukin (IL)-8 is a proinflammatory C-X-C chemokine involved in inflammation underling cardiac diseases, primary or in comorbid condition, such diabetic cardiomyopathy (DCM). The phosphodiesterase type 5 inhibitor sildenafil can ameliorate cardiac conditions by counteracting inflammation. The study aim is t...

journal_title：Journal of endocrinological investigation

authors： Giannattasio S,Corinaldesi C,Colletti M,Di Luigi L,Antinozzi C,Filardi T,Scolletta S,Basili S,Lenzi A,Morano S,Crescioli C

更新日期：2019-06-01 00:00:00

abstract：:Thyroid stimulating hormone (TSH) was measured using a highly sensitive cytochemical bioassay (CBA) technique in normal subjects, in patients with Graves' disease (untreated and treated) and in patients with euthyroid goiter and negative thyrotropin-releasing hormone (TRH)-test. Plasma TSH levels of normal subjects an...

journal_title：Journal of endocrinological investigation

authors： Hashimoto T,Döhler KD,Emrich D,von zur Mühlen A

更新日期：1979-10-01 00:00:00

abstract：BACKGROUND:The data about cardiovascular (CV) changes in patients with asymptomatic primary hyperparathyroidism (PHPT) are scarce. AIM:The aim of this study is to compare cardiac structure and functions in patients with asymptomatic PHPT and controls by using tissue Doppler echocardiography. SUBJECTS AND METHODS:Thir...

journal_title：Journal of endocrinological investigation

authors： Aktas Yılmaz B,Akyel A,Kan E,Ercin U,Tavil Y,Bilgihan A,Cakır N,Arslan M,Balos Toruner F

更新日期：2013-11-01 00:00:00

abstract：:Although it is well known that growth hormone may influence protein metabolism, few investigations have been undertaken on serum protein levels in acromegaly; recently hypoglobulinemia has been observed in this endocrine disorder. In 28 acromegalic patients and 56 control subjects sera have been analyzed for total pro...

journal_title：Journal of endocrinological investigation

authors： Federspil G,Vettor R,Bossi A,Sicolo N

更新日期：1979-04-01 00:00:00

abstract：OBJECTIVE:The relative contribution of fasting and post-prandial glucose to glycated hemoglobin (HbA1c) is controversial. In the present study, we assessed the relationship with HbA1c of fasting and post-prandial glucose measured in a more naturalistic setting, through home glucose self-monitoring or with a continuous ...

journal_title：Journal of endocrinological investigation

authors： Monami M,Lamanna C,Lambertucci L,Longo R,Cocca C,Addante F,Lotti E,Masotti G,Marchionni N,Mannucci E

更新日期：2006-07-01 00:00:00

abstract：:Somatomedin was measured by rat bioassay in samples obtained from renal artery and vein, in order to study the role of this organ in the production of somatomedin activity. The results showed a significant difference, with an increase of the activity in the venous samples. According to the data reported in the literat...

journal_title：Journal of endocrinological investigation

authors： Minuto F,Barreca A,Grimaldi P,Cocco R,Garibotto G,Ferrini S,Giordano G

更新日期：1979-07-01 00:00:00

abstract：BACKGROUND:Increasing evidence showed that telomere length was shorter in age-related diseases, but the mechanism of this phenomenon is still unclear. AIM:To determine whether telomere shortening occurs in Type 1 diabetes (T1D) and Type 2 diabetes (T2D), and explore the effect of antioxidant status on the telomere len...

journal_title：Journal of endocrinological investigation

authors： Ma D,Zhu W,Hu S,Yu X,Yang Y

更新日期：2013-12-01 00:00:00

abstract：:Severe bleeding into the peritoneal cavity from a ruptured ovulatory follicle is a rare complication in women receiving anticoagulation therapy. A number of both surgical and non surgical methods have been proposed to solve this problem. We adopted a novel therapeutic approach in a 40-year old patient who presented wi...

journal_title：Journal of endocrinological investigation

authors： Ulrich U,Rossmanith WG

更新日期：1994-05-01 00:00:00

abstract：:Osteoporosis is a multifactorial chronic disease that may become even more prevalent and more of a public health problem in the decades to come. Recent research has indicated that a number of macro- and micronutrients are involved in the development of bone health. In the past decade it became evident that vitamin K p...

journal_title：Journal of endocrinological investigation

authors： Francucci CM,Rilli S,Fiscaletti P,Boscaro M

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Protein tyrosine phosphatase (PTP)- 1B, encoded by the PTPN1 gene, negatively regulates insulin signaling by dephosphorylating the phosphotyrosine residues of the insulin receptor kinase activation segment. Several rare single nucleotide polymorphisms (SNP) have been linked to diseases accompanying insulin r...

journal_title：Journal of endocrinological investigation

authors： Gu P,Jiang W,Du H,Shao J,Lu B,Wang J,Zou D

更新日期：2010-07-01 00:00:00

abstract：:The adrenomedullary response to stimuli is often elevated in poorly controlled insulin dependent diabetic patients, and it is controversial whether the adrenomedullary hyperactivity induces the suppression of the circadian rhythm of catecholamines. We have studied the urinary excretion of catecholamines in 11 diabetic...

journal_title：Journal of endocrinological investigation

authors： Del Rio G,Carani C,Baldini A,Marrama P,Della Casa L

更新日期：1990-07-01 00:00:00

abstract：:The cause of a poor response to human menopausal gonadotropin (hMG) remains unexplained. To determine whether aromatase activity of cultured granulosa cells obtained from relatively low estradiol (E2) responders (serum E2 < 1000 pg/ml) to hMG therapy differed from that of good responders (E2 > or = 1000 pg/ml), we pro...

journal_title：Journal of endocrinological investigation

authors： Hurst BS,Zacur HA,Schlaff WD,Berkovitz GD

更新日期：1992-09-01 00:00:00

abstract：:Reduced cardiac mass and performances are present in GH deficiency and are counteracted by rhGH replacement. GH and IGF-I possess specific myocardial receptors and have been reported able to exert an acute inotropic effect. Synthetic GH secretagogues (GHS) possess specific pituitary and hypothalamic but even myocardia...

journal_title：Journal of endocrinological investigation

authors： Bisi G,Podio V,Valetto MR,Broglio F,Bertuccio G,Del Rio G,Arvat E,Boghen MF,Deghenghi R,Muccioli G,Ong H,Ghigo E

更新日期：1999-04-01 00:00:00