False-positive diagnosis of adrenal pheochromocytoma on iodine-123-MIBG scan.

abstract：:Several clinical signs might be related to the decline of DHEA secretion in aged people: sarcopenia, osteopenia, atherosclerosis progression, impairment of cognitive and affective performances, deterioration of immunocompetence are the most significant evidences. In addition, in aged people this clinical condition mig...

journal_title：Journal of endocrinological investigation

authors： Valenti G

更新日期：2002-01-01 00:00:00

abstract：:Obesity and insulin resistance are common features of Type 2 Diabetes. A new protein called resistin has been shown to be secreted by adipocytes in mice and to influence insulin sensitivity. The goal of the present study was to investigate the associations between one polymorphism (g-420C>G) of the human resistin gene...

journal_title：Journal of endocrinological investigation

authors： Bouchard L,Weisnagel SJ,Engert JC,Hudson TJ,Bouchard C,Vohl MC,Pérusse L

更新日期：2004-12-01 00:00:00

abstract：:A 39-year-old Danish woman was treated with an oral dose of 400 MBq 131I for a non-toxic goiter with compression symptoms. Serum anti-TPO and TSH receptor antibodies were negative before radioiodine therapy. The patient developed hyperthyroidism four months after treatment and ophthalmopathy after another three months...

journal_title：Journal of endocrinological investigation

authors： Nygaard B,Metcalfe RA,Phipps J,Weetman AP,Hegedüs L

更新日期：1999-06-01 00:00:00

abstract：:To evaluate the influence of chronological age and pubertal development on the hypothalamus-pituitary-adrenal (HPA) axis response to stress, we studied the possible correlations between male pubertal characteristics and salivary cortisol (C), DHEAS and the DHEAS/C ratio before (pre-stress) and after acute exercise-str...

journal_title：Journal of endocrinological investigation

authors： Di Luigi L,Guidetti L,Baldari C,Gallotta MC,Sgrò P,Perroni F,Romanelli F,Lenzi A

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Adiponectin, a fat derived cytokine, is a potential independent contributor to bone mineral density (BMD); however, its action on bone metabolism in humans is still unclear. AIM:The aim of this study was to investigate the relationship of adiponectin with bone mass indices and bone metabolic markers in midd...

journal_title：Journal of endocrinological investigation

authors： Tenta R,Kontogianni MD,Yiannakouris N

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Elevated plasminogen activator inhibitor type 1 (PAI 1) plays an important role in the pathogenesis of excess blood coagulability in obese patients. L-arginine supplementation has shown to be associated with enhanced cardiovascular and metabolic health. The aim of the study was to assess the effect of L-argi...

journal_title：Journal of endocrinological investigation

authors： Bogdanski P,Szulinska M,Suliburska J,Pupek-Musialik D,Jablecka A,Witmanowski H

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:The adiponectin gene has been identified as a susceptibility locus for metabolic syndrome, diabetes and cardiovascular disease. AIM:To examine the influence of two single nucleotide polymorphisms (SNPs) of this gene (+276G>T and +45T>G) on circulating adiponectin concentrations, and to evaluate their relati...

journal_title：Journal of endocrinological investigation

authors： Galcheva SV,Martorana D,Iotova VM,Yotov Y,Neri TM,Street ME

更新日期：2013-11-01 00:00:00

abstract：:The present experiments were undertaken to study the effect of complete food removal on body weight, pituitary growth hormone (GH), plasma GH and glucose concentration in male and female Wistar rats. Plasma and pituitary GH levels were measured by means of a specific radioimmunoassay. Plasma glucose concentration decr...

journal_title：Journal of endocrinological investigation

authors： Gonzalez C,Jolin T

更新日期：1981-01-01 00:00:00

abstract：:Somatostatin and its derivatives have been predominantly studied and succesfully used in endocrinological diseases. This article reviews the rationale of the use of somatostatin and its derivatives in ophthalmology based on current understanding of its action in the eye and summarizes previously published controlled s...

journal_title：Journal of endocrinological investigation

authors： Missotten T,Baarsma GS,Kuijpers RW,van den Born LI,van der Loos T,Croxen R,Hofland LJ,van Hagen PM

更新日期：2005-01-01 00:00:00

abstract：:Leptin may be a possible trigger for puberty. In normal males, it has been shown that leptin increases from the pre-pubertal to the early pubertal stage, and then declines in the late pubertal stage. We examined leptin levels in six male adolescents (mean age 16.3+/-0.6 yr; range 14.2-17.6 yr) with delayed puberty (co...

journal_title：Journal of endocrinological investigation

authors： Giusti M,Guido R,Valenti S,Giordano G

更新日期：1999-01-01 00:00:00

abstract：:Obesity is associated with a number of serious diseases and with a degree of motor disability, but the extent of the risk and functional derangement within the obese population is not yet completely defined. The study aims to evaluate the combined effect of degree of adiposity, body fat distribution and age on selecte...

journal_title：Journal of endocrinological investigation

authors： Lafortuna CL,Agosti F,Proietti M,Adorni F,Sartorio A

更新日期：2006-11-01 00:00:00

abstract：PURPOSE:Though type 2 diabetes mellitus (T2DM) is an important and independent risk factor for coronary artery disease (CAD) in the general population, the impact of T2DM on CAD in patients with familial hypercholesterolemia (FH) is less understood. Thus, the current study aimed to examine the features of FH patients w...

journal_title：Journal of endocrinological investigation

authors： Sun D,Cao YX,You XD,Zhou BY,Li S,Guo YL,Zhang Y,Wu NQ,Zhu CG,Gao Y,Dong QT,Liu G,Dong Q,Li JJ

更新日期：2019-05-01 00:00:00

abstract：:Although TRIAC is bound at least twice as avidly to nuclear receptor as T3, its thyromimetic potency is relatively low and its effect at the pituitary level on thyrotropin (TSH) secretion seems to be dissociated from that at the peripheral tissue level. In order to gain further insight into the complex effects of this...

journal_title：Journal of endocrinological investigation

authors： Beck-Peccoz P,Sartorio A,De Medici C,Grugni G,Morabito F,Faglia G

更新日期：1988-02-01 00:00:00

abstract：:We herein describe a family with thyroid hormone resistance. Thyroid hormones and basal TSH were elevated. Pituitary tumor or abnormality in thyroid hormone binding proteins were ruled out by appropriate tests. Mother and sister of the propositus presented similar abnormal hormonal features but no hyperthyroidism. Ini...

journal_title：Journal of endocrinological investigation

authors： Aguilar Diosdado M,Escobar-Jimenez L,Fernandez Soto ML,Garcia Curiel A,Escobar-Jimenez F

更新日期：1991-09-01 00:00:00

abstract：:Hypoparathyroidism cannot be cured by oral or intravenous calcium supplements. Using molecular biology techniques to induce the production of PTH is an ideal option to treat hypoparathyroidism. In this study, we established a recombinant plasmid encoding a mutant preproPTH with a skeletal muscle creatine kinase promot...

journal_title：Journal of endocrinological investigation

authors： Liu D,Zhu Y,Yang C,Long J,Yao C,Li J,Wang S

更新日期：2012-05-01 00:00:00

abstract：:Peripheral mononuclear cells (MNC) of patients with autoimmune thyroid disease have been shown to proliferate when cultured with human thyroglobulin (hTg). In addition, such a phenomenon is apparent in a certain number of healthy individuals. In this study we have attempted to correlate hTg-induced MNC proliferation, ...

journal_title：Journal of endocrinological investigation

authors： Bagnasco M,Orlandini A,Melioli G,Venuti D,Canonica GW,Ferrara GB

更新日期：1987-04-01 00:00:00

abstract：AIM:We aimed to investigate serum nesfatin-1 level in girls with premature thelarche (PT) and its relationship with anthropometric parameters and leptin, which are involved in the initiation of pubertal process. SUBJECTS-METHODS:Non-obese girls who presented with the complaint of early (2-8 years) and isolated breast ...

journal_title：Journal of endocrinological investigation

authors： Çatlı G,Anık A,Küme T,Çalan ÖG,Dündar BN,Böber E,Abacı A

更新日期：2015-08-01 00:00:00

abstract：:Serial weekly serum samples (for 3 weeks) were obtained from 42 patients with differentiated thyroid cancer (DTC, papillary no.=35, follicular no.=6, Hurthle cell no.=1) for serum thyroid hormone, TSH and TG before and after total thyroidectomy. Serum specimens were also obtained one month after radioiodine (131I) the...

journal_title：Journal of endocrinological investigation

authors： Lima N,Cavaliere H,Tomimori E,Knobel M,Medeiros-Neto G

更新日期：2002-02-01 00:00:00

abstract：:To characterize natriuretic peptide receptor (NPr) gene expression in human tissues, we cloned portions of the cDNAs codifying for NPr with guanylyl cyclase activity (NPr-A and NPr-B) and without guanylyl cyclase activity (NPr-C). Total RNA was extracted from samples taken at surgery from normal human tissues. NPr-A a...

journal_title：Journal of endocrinological investigation

authors： Sarzani R,Dessì-Fulgheri P,Paci VM,Espinosa E,Rappelli A

更新日期：1996-10-01 00:00:00

abstract：:N-Methyl-D-Aspartate(NMDA)-sensitive glutamate receptors, are critically involved in the induction of the learning process. Activation of NMDA receptors by glutamate lead to massive influx of extracellular Ca2+, with ensuing activation of a variety of Ca(2+)-dependent enzymes, including protein kinase C. This triggers...

journal_title：Journal of endocrinological investigation

authors： Caruso S,Agnello C,Campo MG,Nicoletti F

更新日期：1993-12-01 00:00:00

abstract：:Excess production of proopiomelanocortin (POMC)-derived peptides with aldosterone-stimulating activity has been suggested to play a pathogenetic role in idiopathic hyperaldosteronism (IHA). To further investigate this issue, the opiate receptor antagonist naloxone was administered to 14 patients with primary aldostero...

journal_title：Journal of endocrinological investigation

authors： Fallo F,Boscaro M,Sonino N,Mantero F

更新日期：1988-04-01 00:00:00

abstract：PURPOSE:To report the long-term effectiveness and safety of the recombinant human growth hormone Omnitrope®, a somatropin biosimilar to Genotropin®, in Italian patients with growth hormone deficiency (GHD) enrolled in the PATRO Adults study. METHODS:The PATRO Adults study is an ongoing observational, longitudinal, non...

journal_title：Journal of endocrinological investigation

authors： Ferone D,Profka E,Gasco V,Ambrosio MR,Colao A,Di Somma C,Puxeddu E,Arnaldi G,Pagano C,Zecchi E,Pietropoli A,Beck-Peccoz P

更新日期：2017-06-01 00:00:00

abstract：:A possible participation of central serotoninergic or noradrenergic neurons on nyctohemeral periodicity of plasma TSH concentration was studied in the rat. Control rats exhibited normal nyctohemeral fluctuations of plasma TSH characterized by high AM (09:30) and low PM (18:30) values (397 +/- 45 vs. 207 +/- 28 ng/ml, ...

journal_title：Journal of endocrinological investigation

authors： Fukuda H,Mori M,Ohshima K,Kobayashi I

更新日期：1980-07-01 00:00:00

abstract：BACKGROUND:We previously identified a four-generation family with medullary thyroid cancer (MTC) and a germline p.Y791F RET mutation whose cancer lacked a strong genotype-phenotype correlation. The entire gene coding region of the RET gene should be sequenced when genotype-phenotype discrepancies are observed in patien...

journal_title：Journal of endocrinological investigation

authors： Valente FO,Dias da Silva MR,Camacho CP,Kunii IS,Bastos AU,da Fonseca CC,Simião HP,Tamanaha R,Maciel RM,Cerutti JM

更新日期：2013-12-01 00:00:00

abstract：PURPOSE:Interleukin (IL)-8 is a proinflammatory C-X-C chemokine involved in inflammation underling cardiac diseases, primary or in comorbid condition, such diabetic cardiomyopathy (DCM). The phosphodiesterase type 5 inhibitor sildenafil can ameliorate cardiac conditions by counteracting inflammation. The study aim is t...

journal_title：Journal of endocrinological investigation

authors： Giannattasio S,Corinaldesi C,Colletti M,Di Luigi L,Antinozzi C,Filardi T,Scolletta S,Basili S,Lenzi A,Morano S,Crescioli C

更新日期：2019-06-01 00:00:00

abstract：:General dynamic penile color doppler ultrasound (D-PCDU) screening in patients with erectile dysfunction (ED) has been questioned due to an inadequate cost-benefit ratio. The aim of the present study is to evaluate the validity of different risk scores in the identification of patients being screened for arteriogenic ...

journal_title：Journal of endocrinological investigation

authors： Corona G,Mannucci E,Fisher AD,Lotti F,Bandini E,Vignozzi L,Balercia G,Paggi F,Petrone L,Forti G,Maggi M

更新日期：2008-12-01 00:00:00

abstract：:We evaluated the oral calcium-loading test (OCLT) in diagnosing normocalcemic primary hyperparathyroidism. Calcium and PTH levels were measured before, 60, 120 and 180 min after oral 1 g of calcium gluconolactate administration in 102 consecutive females with high circulating PTH levels, and 25 controls. Patients were...

journal_title：Journal of endocrinological investigation

authors： Hagag P,Revet-Zak I,Hod N,Horne T,Rapoport MJ,Weiss M

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:Myogenesis is susceptible to the availability of nutrients and humoral factors and suboptimal fetal environments affect the number of myofibers and muscle mass. AIM:We examined the mechanisms regulating cell cycle progression and arrest in skeletal myoblasts. MATERIALS AND METHODS:Mouse C2C12 myoblasts wer...

journal_title：Journal of endocrinological investigation

authors： Grabiec K,Gajewska M,Milewska M,Błaszczyk M,Grzelkowska-Kowalczyk K

更新日期：2014-03-01 00:00:00

abstract：:In order to precise the relationships between TSH, FT3, and FT4 nycthemeral variations and the relationships between thyroid hormone variations and sleep, 8 healthy young males were studied twice, once during a 24-h experiment with normal nocturnal sleep, and once during a night of sleep deprivation. The subjects rece...

journal_title：Journal of endocrinological investigation

authors： Goichot B,Brandenberger G,Saini J,Wittersheim G,Follenius M

更新日期：1994-03-01 00:00:00

abstract：INTRODUCTION:Phosphodiesterase 5 inhibitors (PDE5i) were developed while investigating novel treatments for coronary artery disease, but their andrological side effects shifted their indication toward the management of erectile dysfunction. Although PDE5i are now also indicated for pulmonary arterial hypertension and t...

journal_title：Journal of endocrinological investigation

authors： Pofi R,Gianfrilli D,Badagliacca R,Di Dato C,Venneri MA,Giannetta E

更新日期：2016-02-01 00:00:00