"Madonna of the Pinks" and "Madonna Dell'Impannata": Raphael Sanzio (1483-1520).

abstract：BACKGROUND AND AIMS:Several studies investigated the possible role of adipokines during chronic viral hepatitis, not producing defined results neither clearly establishing their behavior in course of anti-viral treatment. Our study evaluated blood concentrations of adiponectin and resistin in patients with chronic hepa...

journal_title：Journal of endocrinological investigation

authors： Durazzo M,Belci P,Niro G,Collo A,Grisoglio E,Ambrogio V,Spandre M,Fontana R,Gambino R,Cassader M,Bo S

更新日期：2013-09-01 00:00:00

abstract：:Diagnosis of endogenous hyperinsulinism caused by insulinoma is based on confirmation of hypoglycemia during the symptoms associated to elevated insulin levels. Patients with insulinoma may demonstrate an excessive insulin response and subsequent hypoglycemia after 1 mg of glucagon iv injection. Glucagon test was perf...

journal_title：Journal of endocrinological investigation

authors： Felício JS,Martins CL,Mileo KB,Semer M,Kalinin L,Nery M,Machado MC,Liberman B

更新日期：2012-06-01 00:00:00

abstract：:The authors report the profiles of luteinizing hormone (LH), estradiol (E2), progesterone (P) and androstenedione (A) in some female pigs with altered plasma hormonal levels. Twenty cycles are described and 19 out of them are characterized by low plasma P in luteal phase of different etiology, at least as measured by ...

journal_title：Journal of endocrinological investigation

authors： Pierantoni R,Genazzani AR,Perotti L,Enne G,Inaudi P,d'Istria M,Musarò MA,Citarella F,Fasano S,Delrio G

更新日期：1983-02-01 00:00:00

abstract：:Several studies suggest that nitric oxide (NO) production is impaired in diabetes mellitus. Reduced levels of NO could contribute to cardiovascular mortality. Furthermore, NO synthesis is impaired in glutathione (GSH)-depleted human umbilical vein endothelial cells and GSH is reduced in patients with type 2 diabetes m...

journal_title：Journal of endocrinological investigation

authors： Martina V,Bruno GA,Zumpano E,Origlia C,Quaranta L,Pescarmona GP

更新日期：2001-01-01 00:00:00

abstract：:The assessment of growth hormone (GH) secretory status is often difficult because of the intermittent nature of GH release and resulting wide swings in plasma GH levels. Urinary GH excretion holds promise as an index of integrated plasma GH free of this limitation, but technical problems have prevented its use until r...

journal_title：Journal of endocrinological investigation

authors： Winer LM,Shaw MA,Baumann G

更新日期：1989-07-01 00:00:00

abstract：:To assess the role of the renin-angiotensin system in the control of aldosterone reease in response to heat exposure, 6 sodium restricted subjects were studied on three random experimental days: a control day and two heat exposure days (46C, 35 mbar, 90 min) with and without propranolol. Plasma aldosterone, renin acti...

journal_title：Journal of endocrinological investigation

authors： Brandenberger G,Follenius M,Oyono S

更新日期：1980-10-01 00:00:00

abstract：OBJECTIVE:Blepharophimosis syndrome (BPES) is an autosomal dominant genetic condition resulting from heterozygous mutations in the FOXL2 gene and clinically characterized by an eyelid malformation associated (type I) or not (type II) with premature ovarian failure. The distinction between the two forms is critical for ...

journal_title：Journal of endocrinological investigation

authors： Nuovo S,Passeri M,Di Benedetto E,Calanchini M,Meldolesi I,Di Giacomo MC,Petruzzi D,Piemontese MR,Zelante L,Sangiuolo F,Novelli G,Fabbri A,Brancati F

更新日期：2016-02-01 00:00:00

abstract：:Orbital fibroblasts exhibit a unique phenotype including exaggerated responses to proinflammatory cytokines. We hypothesize that the unusual susceptability of these fibroblasts to molecular cues underlies the involvement of the orbit in Graves' ophthalmopathy. A number of attributes of orbital fibroblasts are reviewed...

journal_title：Journal of endocrinological investigation

authors： Smith TJ

更新日期：2004-03-01 00:00:00

abstract：:Anorexia nervosa (AN) is an eating disorder characterized by self-induced starvation due to fear of adiposity. Ghrelin, gastric peptide with potent orexigenic, adipogenic, GH-releasing and metabolic properties, is elevated in AN. We have previously shown that intervention with exogenous ghrelin is not effective in ter...

journal_title：Journal of endocrinological investigation

authors： Miljic D,Djurovic M,Pekic S,Doknic M,Stojanovic M,Milic N,Casanueva FF,Ghatei M,Popovic V

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:The aim of this study is to analyze our preliminary results from minimally invasive video-assisted parathyroidectomy (MIVAP) and demonstrate the feasibility of MIVAP also in non-referral centers. MATERIAL AND METHODS:During a period from June 2005 to January 2008, in the General Surgery Department of Univer...

journal_title：Journal of endocrinological investigation

authors： Dobrinja C,Trevisan G,Liguori G

更新日期：2009-02-01 00:00:00

abstract：:In mild glucose intolerance plasma concentration of C-peptide seems to give an estimate of pancreatic B cell secretion more reliable than plasma insulin itself. In the present study we measured the plasma levels of insulin and C-peptide after oral glucose load in 100 mildly glucose intolerant subjects, focusing our at...

journal_title：Journal of endocrinological investigation

authors： Bonora E,Zavaroni I,Manicardi V,Coscelli C,Butturini U

更新日期：1986-10-01 00:00:00

abstract：:Leptin may be a possible trigger for puberty. In normal males, it has been shown that leptin increases from the pre-pubertal to the early pubertal stage, and then declines in the late pubertal stage. We examined leptin levels in six male adolescents (mean age 16.3+/-0.6 yr; range 14.2-17.6 yr) with delayed puberty (co...

journal_title：Journal of endocrinological investigation

authors： Giusti M,Guido R,Valenti S,Giordano G

更新日期：1999-01-01 00:00:00

abstract：PURPOSE:To investigate the effects of metabolic abnormalities, hyperandrogenemia and ovulation induction by clomiphene/acupuncture on liver function parameters among women with polycystic ovary syndrome (PCOS). METHODS:This is a secondary analysis of a randomized controlled trial. All 1000 subjects were diagnosed as P...

journal_title：Journal of endocrinological investigation

authors： Cai WY,Gao JS,Luo X,Ma HL,Ge H,Liu N,Xia Q,Wang Y,Han BW,Wu XK

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND AND AIM:Familial adenomatous polyposis (FAP) is an autosomal inherited syndrome characterized by hundreds to thousands colorectal adenomatous polyps with oncological transformation lifetime risk of 100%. FAP is mainly associated with mutations in APC (autosomal dominant inheritance) or MUTYH (autosomal reces...

journal_title：Journal of endocrinological investigation

authors： Martayan A,Sanchez-Mete L,Baldelli R,Falvo E,Barnabei A,Conti L,Giacomini P,Appetecchia M,Stigliano V

更新日期：2010-10-01 00:00:00

abstract：CONTEXT:The latest guidelines of the 4th International Workshop on Asymptomatic Primary Hyperparathyroidism (aPHPT) reintroduced hypercalciuria (i.e. urinary calcium > 400 mg/day) as criterion for surgery. However, the value of hypercalciuria as a predictor of nephrolithiasis and the correct cut-off values still need t...

journal_title：Journal of endocrinological investigation

authors： Saponaro F,Cetani F,Mazoni L,Apicella M,Di Giulio M,Carlucci F,Scalese M,Pardi E,Borsari S,Bilezikian JP,Marcocci C

更新日期：2020-05-01 00:00:00

abstract：:The effect of the somatostatin analog (GHRIH-A) D-Trp8, D-Cys14 on plasma levels of growth hormone, pancreatic glucagon, insulin and glucose was studied in four acromegalic patients and in four maturity-onset mild diabetics. Acromegalics received a bolus iv injection of 25 microgram of GHRIH-A, followed by a continuou...

journal_title：Journal of endocrinological investigation

authors： Trovati M,Massara F,Camanni F,Molinatti GM,Lorenzati R,Pagano GF

更新日期：1980-04-01 00:00:00

abstract：PURPOSE:We examined auxological changes in growth hormone (GH)-treated children in Italy using data from the Italian cohort of the multinational observational Genetics and Neuroendocrinology of Short Stature International Study (GeNeSIS) of pediatric patients requiring GH treatment. METHODS:We studied 711 children (me...

journal_title：Journal of endocrinological investigation

authors： Cappa M,Iughetti L,Loche S,Maghnie M,Vottero A,GeNeSIS National Board on behalf of the GeNeSIS Italian Investigators.

更新日期：2016-06-01 00:00:00

abstract：:Hypocalcemia associated with labor and lactation is a rare condition reported previously in patients with hypovitaminosis D. We here describe a case of a young woman in whom symptomatic severe hypocalcemia appeared after her second delivery, early in lactation. At the end of lactation the condition worsened. We review...

journal_title：Journal of endocrinological investigation

authors： Durst R,Meirovitz A,Gross D,Kolker O,Muszkat M

更新日期：2002-06-01 00:00:00

abstract：:Seventy years after the first successful radioiodine treatment of metastatic differentiated thyroid cancer (DTC), radioiodine (131I) therapy for this type of tumor is still without alternative. During the last decade, some key issues such as individual dosimetry, and preparation of 131I therapy by recombinant human TS...

journal_title：Journal of endocrinological investigation

authors： Luster M,Hänscheid H,Freudenberg LS,Verburg FA

更新日期：2012-01-01 00:00:00

abstract：INTRODUCTION:Growth hormone resistance defines several genetic (primary) and acquired (secondary) pathologies that result in completely or partially interrupted activity of growth hormone. An archetypal disease of this group is the Laron-type dwarfism caused by mutations in growth hormone receptors. The diagnosis is ba...

journal_title：Journal of endocrinological investigation

authors： Kurtoğlu S,Hatipoglu N

更新日期：2016-01-01 00:00:00

abstract：:Impaired glucose tolerance is present in many acromegalic patients and treatment with somatostatin analogs has variable effects on glycemic control. The aim of this study was to compare the effects of 2 somatostatin analogs on glucose metabolism, lanreotide slow release (L-SR) and octreotide long acting release (O-LAR...

journal_title：Journal of endocrinological investigation

authors： Ronchi C,Epaminonda P,Cappiello V,Beck-Peccoz P,Arosio M

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:One of the major topics in modern societies is the study of relationships between diet, stress and incidence of metabolic disorders. AIM:This study aimed to investigate possible impairment in glucose-stimulated insulin secretion induced by a high-fat (cow intra-abdominal fat) diet in response to acute stres...

journal_title：Journal of endocrinological investigation

authors： Ghalami J,Zardooz H,Rostamkhani F,Farrokhi B,Hedayati M

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Diabetes mellitus is frequently observed in patients with acromegaly. Current therapies for acromegaly may impact glucose regulation, influencing insulin sensitivity and secretion. The question whether these therapies modify control and progression of diabetes once present is still open. AIM:Aim of our stud...

journal_title：Journal of endocrinological investigation

authors： Cambuli VM,Galdiero M,Mastinu M,Pigliaru F,Auriemma RS,Ciresi A,Pivonello R,Amato M,Giordano C,Mariotti S,Colao A,Baroni MG

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Increasing evidence showed that telomere length was shorter in age-related diseases, but the mechanism of this phenomenon is still unclear. AIM:To determine whether telomere shortening occurs in Type 1 diabetes (T1D) and Type 2 diabetes (T2D), and explore the effect of antioxidant status on the telomere len...

journal_title：Journal of endocrinological investigation

authors： Ma D,Zhu W,Hu S,Yu X,Yang Y

更新日期：2013-12-01 00:00:00

abstract：:Data concerning the cardiovascular manifestations of primary hyperparathyroidism (PHPT) are inconsistent, which is due, in part, to the decrease in disease severity over the last several decades. In areas where patients tend to be more symptomatic, data support the presence of cardiovascular findings including myocard...

journal_title：Journal of endocrinological investigation

authors： Walker MD,Silverberg SJ

更新日期：2008-10-01 00:00:00

abstract：PURPOSE:Acromegaly is a rare disorder existed in the result of overproduction of growth hormone (GH). The disorder is associated with increased cardiovascular risk factors and metabolic abnormalities. Urotensin II (UII), a secreted vasoactive peptide hormone, belonging somatostatin superfamily, plays an essential role ...

journal_title：Journal of endocrinological investigation

authors： Demirpence M,Guler A,Yilmaz H,Sayin A,Pekcevik Y,Turkon H,Colak A,Ari EM,Aslanipour B,Kocabas GU,Calan M

更新日期：2019-02-01 00:00:00

abstract：PURPOSE:Although men with spinal cord injury (SCI) exhibit a prostate volume significantly smaller compared to age-matched able-bodied men, the independent association of lower prostate volume with its putative determinants has never been analyzed in this population. This study was designed to identify variables indepe...

journal_title：Journal of endocrinological investigation

authors： D'Andrea S,Castellini C,Minaldi E,Totaro M,Felzani G,Francavilla S,Francavilla F,Barbonetti A

更新日期：2020-11-01 00:00:00

abstract：:The DAZ (deleted in azoospermia) gene family is considered the major AZFc ("azoospermia factor" c) candidate responsible for male infertility. However, other genes have been recently mapped to this region and they could contribute to the AZFc phenotype. In particular, the testis-specific CDY1 (chromadomain protein 1) ...

journal_title：Journal of endocrinological investigation

authors： Ferlin A,Moro E,Rossi A,Foresta C

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:Subtotal parathyroidectomy (SP) and total parathyroidectomy (TP) with autotransplantation (TPai) are the most commonly adopted operations for the treatment of secondary hyperparathyroidism (2HPT). TP without autotransplantation had previously been confined to patients with advanced dialytic vintage, not elig...

journal_title：Journal of endocrinological investigation

authors： Conzo G,Perna AF,Sinisi AA,Palazzo A,Stanzione F,Della Pietra C,Livrea A

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:Although a nation-wide salt iodization program on voluntary basis was implemented in 2005, many areas in our country are still characterized by mild iodine deficiency. Differently from the rest of Italy, an efficient program of iodine prophylaxis was implemented in 1981 in the Autonomous Province of Bolzano. Th...

journal_title：Journal of endocrinological investigation

authors： Olivieri A,Radetti G,Medda E,Italian Study Group for Congenital Hypothyroidism.

更新日期：2015-02-01 00:00:00