Abstract:
:Experimental studies show that some compounds in tobacco smoke are transplacental carcinogens, but epidemiological data on maternal smoking and childhood cancer are inconclusive. Using the national Swedish Medical Birth and Cancer Registries, the incidence of cancer was followed through 1987 in a cohort of 497,051 children born 1982-1987 for whom information was available on maternal smoking at 2-3 months of pregnancy. A total of 327 cancers appeared including 198 solid tumours and 129 cancers of the lymphatic and haematopoietic system. The overall relative risk for cancer in children with mothers reporting smoking during pregnancy was 0.99 (95% confidence interval (CI): 0.78-1.27). Corresponding risks for solid tumours and cancers of the lymphatic/haematopoietic system were 0.96 (0.70-1.32) and 1.04 (0.71-1.52), respectively. There was no consistent increase in risk for cancer of different sites or in relation to number of cigarettes smoked per day.
journal_name
Int J Epidemioljournal_title
International journal of epidemiologyauthors
Pershagen G,Ericson A,Otterblad-Olausson Pdoi
10.1093/ije/21.1.1keywords:
subject
Has Abstractpub_date
1992-02-01 00:00:00pages
1-5issue
1eissn
0300-5771issn
1464-3685journal_volume
21pub_type
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