The French Addenbrooke's cognitive examination is effective in detecting dementia in a French-speaking population.

abstract：BACKGROUND/AIMS:Dementia cafés are becoming widespread as a new approach to dementia care, but their operational procedures and significance have not been adequately studied. METHODS:On-the-job training (OJT) for professionals planning to operate a dementia café in the future was conducted in a pioneering dementia caf...

journal_title：Dementia and geriatric cognitive disorders

authors： Takechi H,Sugihara Y,Matsumoto H,Yamada H

更新日期：2018-01-01 00:00:00

abstract：:A substantive overlap between the clinical syndromes of frontal lobe dementia (FLD), frontotemporal dementia (FTD), or primary progressive aphasia (PPA), and corticobasal degeneration syndrome (CBDS) has been demonstrated in a population of 55 patients followed for more than 3 years in a cognitive neurology clinic. Pa...

journal_title：Dementia and geriatric cognitive disorders

authors： Kertesz A,Davidson W,Munoz DG

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND/AIMS:To compare neuropsychiatric symptoms in patients with Alzheimer's disease (AD) and dementia with Lewy bodies(DLB). METHODS:Neuropsychiatric symptoms and caregiver distress were assessed using the Neuropsychiatric Inventory (NPI) in mild DLB (n = 57) and AD (n = 126), and compared across the two groups ...

journal_title：Dementia and geriatric cognitive disorders

authors： Bjoerke-Bertheussen J,Ehrt U,Rongve A,Ballard C,Aarsland D

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Although QOL is an important indicator to assess multiple facets of life, the QOL of Alzheimer's disease (AD) subjects with impaired cognitive ability due to dementia has not yet been fully investigated. In this study, we developed the Japanese version of the Quality of Life-Alzheimer's disease (QOL-AD) scal...

journal_title：Dementia and geriatric cognitive disorders

authors： Matsui T,Nakaaki S,Murata Y,Sato J,Shinagawa Y,Tatsumi H,Furukawa TA

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND/AIM:The objective was to examine cohort changes in cognitive function in 2 cohorts of centenarians born 10 years apart. METHODS:The Longitudinal Study of Danish Centenarians comprises all Danes reaching the age of 100 in the period April 1, 1995 through May 31, 1996. A total of 207 out of 276 persons partic...

journal_title：Dementia and geriatric cognitive disorders

authors： Engberg H,Christensen K,Andersen-Ranberg K,Jeune B

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:The aim of this study was to explore the relationship between cerebrospinal fluid biomarkers and neuropsychiatric symptoms in people with Alzheimer's disease. Psychosis, agitation, apathy and depression were assessed using standardised measures in 32 patients with mild Alzheimer's disease. METHODS:The level...

journal_title：Dementia and geriatric cognitive disorders

authors： Skogseth R,Mulugeta E,Jones E,Ballard C,Rongve A,Nore S,Alves G,Aarsland D

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cognitive impairment (CI) is frequent after stroke, but data from population-based stroke cohorts on the natural course of CI are limited. The purpose of this study was to determine changes in cognitive status over 3 years after stroke. METHODS:Data were collected from the Erlangen Stroke Projec...

journal_title：Dementia and geriatric cognitive disorders

authors： Liman TG,Heuschmann PU,Endres M,Flöel A,Schwab S,Kolominsky-Rabas PL

更新日期：2011-01-01 00:00:00

abstract：:A correlation between a 5-nucleotide deletion polymorphism in the A2M gene and an enhanced risk of developing Alzheimer's disease (AD) was reported. We studied this polymorphism in sporadic AD patients and patients with frontotemporal dementia (FTD) by using an electrophoretical separation of PCR products on a Metapho...

journal_title：Dementia and geriatric cognitive disorders

authors： Nicosia F,Alberici A,Benussi L,Gasparini L,Ghidoni R,Mazzoli F,Zanetti O,Frisoni GB,Geroldi C,Binetti G

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND/AIMS:The aims of this study were to validate the newly developed version of the Addenbrooke's Cognitive Examination (ACE-III) against standardised neuropsychological tests and its predecessor (ACE-R) in early dementia. METHODS:A total of 61 patients with dementia (frontotemporal dementia, FTD, n = 33, and A...

journal_title：Dementia and geriatric cognitive disorders

authors： Hsieh S,Schubert S,Hoon C,Mioshi E,Hodges JR

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:In a previous study, low-frequency (0.5 Hz) cranial electrostimulation (CES) neither improved the rest-activity rhythm nor reduced the level of salivary cortisol in patients with probable Alzheimer's disease (AD). To investigate whether the frequency of CES was responsible for these negative findings, we set ...

journal_title：Dementia and geriatric cognitive disorders

authors： Scherder E,Knol D,van Tol MJ,van Someren E,Deijen JB,Swaab D,Scheltens P

更新日期：2006-01-01 00:00:00

abstract：:The Fas antigen (CD95) is a cell surface receptor that mediates cell apoptosis signalling. Recent investigations have shown that Fas-regulated apoptosis was linked to neurodegenerative lesions in the brain of patients with Alzheimer's disease (AD). Here data regarding the association of two polymorphisms of the Fas pr...

journal_title：Dementia and geriatric cognitive disorders

authors： Chiappelli M,Nasi M,Cossarizza A,Porcellini E,Tumini E,Pinti M,Troiano L,Franceschi M,Licastro F

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Studies of associations between serum lipids and Alzheimer's disease (AD) or other dementias in the elderly show conflicting results, perhaps due to misclassification of the various dementias. METHODS:For 358 nursing home residents, serum lipids were studied at admission and diagnoses established at autopsy...

journal_title：Dementia and geriatric cognitive disorders

authors： Lesser GT,Haroutunian V,Purohit DP,Schnaider Beeri M,Schmeidler J,Honkanen L,Neufeld R,Libow LS

更新日期：2009-01-01 00:00:00

abstract：:This study examines the associations between education, cerebral perfusion, and cognitive test performance among 132 patients with Alzheimer's disease. The participants had had between 0 and 19 years of formal schooling, and had either mild or moderate dementia according to the Clinical Dementia Rating Scale. Cerebral...

journal_title：Dementia and geriatric cognitive disorders

authors： Liao YC,Liu RS,Teng EL,Lee YC,Wang PN,Lin KN,Chung CP,Liu HC

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND/AIMS:Current findings suggest the existence of a category of fast cognitive decliners with a poorer prognosis but better treatment response. Our study aimed at confirming the concept of fast decliners at the time of Alzheimer's disease (AD) diagnosis which best predicts mortality, in an unselected sample. M...

journal_title：Dementia and geriatric cognitive disorders

authors： Carcaillon L,Pérès K,Péré JJ,Helmer C,Orgogozo JM,Dartigues JF

更新日期：2007-01-01 00:00:00

abstract：:The present study investigated the accuracy of an extended version of the Delayed Word Recall (DWR) test in distinguishing patients with very mild Alzheimer's disease (AD) (Mini Mental State Examination score > or = 23) from community-dwelling depressed/dysthymic patients. The DWR test was administered to 26 non-depre...

journal_title：Dementia and geriatric cognitive disorders

authors： Coen RF,Kirby M,Swanwick GR,Maguire CP,Walsh JB,Coakley D,O'Neill D,Lawlor BA

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND/AIMS:Conversion rates to dementia are known to be high for patients with mild cognitive impairment (MCI), but the diagnosis of MCI is very time-consuming. Since the Clock Drawing Test (CDT) is quick to administer, it will be of interest to compare the predictive validity of the CDT and of an MCI diagnosis fo...

journal_title：Dementia and geriatric cognitive disorders

authors： Ehreke L,Luppa M,König HH,Villringer A,Riedel-Heller SG

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND/AIMS:We investigated the histopathological correlates of white matter hyperintensities (WMHs) in participants with Alzheimer's disease (AD) or cerebrovascular disease, and in aged controls. METHODS:We reviewed 57 participants who had neuropathology and in whom neuroimaging was done. In addition to AD pathol...

journal_title：Dementia and geriatric cognitive disorders

authors： Shim YS,Yang DW,Roe CM,Coats MA,Benzinger TL,Xiong C,Galvin JE,Cairns NJ,Morris JC

更新日期：2015-01-01 00:00:00

abstract：INTRODUCTION:Frontotemporal dementia (FTD) is a more common cause of dementia than previously recognised. Few data are available regarding the natural course of FTD in terms of survival, nursing home admission and causes of death. METHODS:An observational study of all consecutive patients referred to the memory centre...

journal_title：Dementia and geriatric cognitive disorders

authors： Pasquier F,Richard F,Lebert F

更新日期：2004-01-01 00:00:00

abstract：:The aim of this study was to determine the frequency of ubiquitin-positive inclusions (UPI) in dementia lacking distinctive histology (DLDH), and their relationship to other pathologic features, such as hippocampal sclerosis (HpScl), as well as genetic factors. Routine and immunohistochemical studies were carried out ...

journal_title：Dementia and geriatric cognitive disorders

authors： Josephs KA,Jones AG,Dickson DW

更新日期：2004-01-01 00:00:00

abstract：:Apolipoprotein E (APOE) is the major genetic risk factor for late-onset Alzheimer's disease (AD) and has also been implicated in cardiovascular disease, cognitive decline and cognitive changes in healthy ageing. The aim of this paper is to systematically review and critically assess the association between the APOE ge...

journal_title：Dementia and geriatric cognitive disorders

authors： Cherbuin N,Leach LS,Christensen H,Anstey KJ

更新日期：2007-01-01 00:00:00

abstract：:In 21 patients suffering from Binswanger's disease (BD) and in 53 patients suffering from Alzheimer's disease, we measured cerebrospinal fluid (CSF) concentrations of somatostatin-like immunoreactivity (SLI), high molecular weight form somatostatin (HMV-SST), somatostatin-25/28 (SST-25/28), somatostatin-14 (SST-14), D...

journal_title：Dementia and geriatric cognitive disorders

authors： Strittmatter M,Hamann GF,Grauer MT,Cramer H,Schimrigk K

更新日期：1997-01-01 00:00:00

abstract：:The present investigation reports the application of regional cerebral blood flow (rCBF; (133)Xe method) to prognostic purposes in a consecutive series of 76 patients (mean age 68.4 +/- 8.7 years) with probable Alzheimer's disease (AD; NINCDS-ADRDA criteria). The likelihood that rCBF from a posterior temporal-inferior...

journal_title：Dementia and geriatric cognitive disorders

authors： Nobili F,Copello F,Buffoni F,Vitali P,Girtler N,Bordoni C,Safaie-Semnani E,Mariani G,Rodriguez G

更新日期：2001-03-01 00:00:00

abstract：INTRODUCTION:Gait speed (GS) is a predictor of negative outcomes in older adults and in those in risk to develop cognitive impairment; as such, it has been associated with dementia. Studies in Latin-American older adults showing this association are scarce. This study aimed to evaluate the relationship between GS and d...

journal_title：Dementia and geriatric cognitive disorders

authors： Garcia-Cifuentes E,Márquez I,Vasquez D,Aguillon D,Borda MG,Lopera F,Cano-Gutierrez C

更新日期：2020-11-18 00:00:00

abstract：BACKGROUND:Semantic dementia (SD). OBJECTIVE:To identify the pattern of decline of cerebral glucose metabolism in SD using cerebral (18)F-fluoro-2-desoxy-D-glucose positron emission tomography scanning ((18)F-FDG-PET). METHODS:Eight patients with SD underwent (18)F-FDG-PET at baseline and at re-examination in average...

journal_title：Dementia and geriatric cognitive disorders

authors： Diehl-Schmid J,Grimmer T,Drzezga A,Bornschein S,Perneczky R,Forstl H,Schwaiger M,Kurz A

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVE:The study was designed to determine the acceptability, feasibility and validity of measuring quality of life in a representative sample of dementia patients with a generic instrument, the Duke Health Profile. METHOD:The French version of the Duke Health Profile was administered to 148 subjects with a mental ...

journal_title：Dementia and geriatric cognitive disorders

authors： Novella J,Ankri J,Morrone I,Guillemin F,Jolly D,Jochum C,Ploton L,Blanchard F

更新日期：2001-03-01 00:00:00

abstract：:The membrane-bound glycoprotein, amyloid precursor protein (APP), plays a central role in Alzheimer's disease (AD). The present paper investigates the neuritogenic-neurotoxic properties of this protein and relates them to possible aetiopathological mechanisms in AD. Marked differences in neuritic differentiation were ...

journal_title：Dementia and geriatric cognitive disorders

authors： Neill D,Hughes D,Leake A,Morris C,Jones D,Oakley A,Edwardson J,Estibeiro P

更新日期：2001-01-01 00:00:00

abstract：:Accumulating evidence suggests that butyrylcholinesterase (BuChE) plays an important role in the progression of cognitive deficits and Alzheimer-type pathology in dementia patients. We examined the relationship between the K variant of BuChE and the severity of deposits of amyloid (Abeta(1-42)) and phosphorylated tau ...

journal_title：Dementia and geriatric cognitive disorders

authors： Ballard C,Morris C,Kalaria R,McKeith I,Perry R,Perry E

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND/AIM:The prevalence of cognitive symptoms in recently diagnosed Parkinson's disease (PD) patients may be as high as 60%. We report a novel deep brain stimulation (DBS) strategy targeting both motor and cognitive symptoms. METHODS:A PD patient diagnosed with mild cognitive impairment underwent DBS surgery tar...

journal_title：Dementia and geriatric cognitive disorders

authors： Nombela C,Lozano A,Villanueva C,Barcia JA

更新日期：2019-01-01 00:00:00

abstract：:Mild cognitive impairment (MCI) is regarded as a precursor to dementia, but not all patients with MCI develop dementia. We followed up 165 elderly outpatients with MCI for a mean of 3 years. The aims were (1) to investigate the risk of conversion to dementia for different MCI subtypes diagnosed according to standardiz...

journal_title：Dementia and geriatric cognitive disorders

authors： Ravaglia G,Forti P,Maioli F,Martelli M,Servadei L,Brunetti N,Pantieri G,Mariani E

更新日期：2006-01-01 00:00:00

abstract：:Primary central nervous system lymphoma (PCNSL) usually presents with clinical and neuroimaging findings consistent with single or multiple intracranial mass lesions. On cranial magnetic resonance imaging (MRI), such lesions are nearly always contrast enhancing, reflecting disruption of the blood-brain barrier at the ...

journal_title：Dementia and geriatric cognitive disorders

authors： Bakshi R,Mazziotta JC,Mischel PS,Jahan R,Seligson DB,Vinters HV

更新日期：1999-03-01 00:00:00