Abstract：
:The aim of the study was to investigate the potential association of epilepsy and EEG abnormalities with autistic regression and mental retardation. We examined a group of 77 autistic children (61 boys, 16 girls) with an average age of 9.1 +/- 5.3 years. Clinical interview, neurological examination focused on the evaluation of epilepsy, IQ testing, and 21-channel EEG (including night sleep EEG recording) were performed. Normal EEGs were observed in 44.4% of the patients, non-epileptiform abnormal EEGs in 17.5%, and abnormal EEGs with epileptiform discharges in 38.1% of the patients. Epilepsy was found in 22.1% of the subjects. A history of regression was reported in 25.8% of the patients, 54.8% of the sample had abnormal development during the first year of life, and 79.7% of the patients were mentally retarded. Autistic regression was significantly more frequent in patients with epilepsy than in non-epileptic patients (p = 0.003). Abnormal development during the first year of life was significantly associated with epileptiform EEG abnormalities (p = 0.014). Epilepsy correlated significantly with mental retardation (p = 0.001). Although the biological basis and possible causal relationships of these associations remain to be explained, they may point to different subgroups of patients with autistic spectrum disorders.
journal_name
Eur Child Adolesc Psychiatryjournal_title
European child & adolescent psychiatryauthors
Hrdlicka M,Komarek V,Propper L,Kulisek R,Zumrova A,Faladova L,Havlovicova M,Sedlacek Z,Blatny M,Urbanek Tdoi
10.1007/s00787-004-0353-7keywords:
subject
Has Abstractpub_date
2004-08-01 00:00:00pages
209-13issue
4eissn
1018-8827issn
1435-165Xjournal_volume
13pub_type
杂志文章abstract：:This study assesses family stress, family functioning and emotional/behavioural problems in a sample of 80 formerly daytreated or residentially treated boys after a mean discharge period of four years. Family stress was assessed with a Questionnaire of Life Events (QLE) and family functioning with the Family Adaptabil...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/BF01987963
更新日期：1995-01-01 00:00:00
abstract：:The purpose of this study was to test child and adolescent psychosocial and psychopathological risk factors as predictors of adult criminal outcomes in a Swiss community sample. In particular, the role of active and avoidant problem coping in youths was analysed. Prevalence rates of young adult crime convictions based...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-013-0458-y
更新日期：2014-05-01 00:00:00
abstract：:Genetic epidemiological studies of Autism Spectrum Disorders (ASDs) based on twin pairs ascertained from the population and thoroughly assessed to obtain a high degree of diagnostic validity are few. All twin pairs aged 3-14 years in the nationwide Danish Twin Registry were approached. A three-step procedure was used....
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-013-0419-5
更新日期：2014-01-01 00:00:00
abstract：:Seven children and young adults with definite signs of Asperger syndrome were administered a battery of tests designed to test: intelligence; left and right cerebral hemisphere functioning; ability to discriminate eye gaze; and social judgment. The subjects revealed a non significant tendency to have a higher verbal I...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/BF01978114
更新日期：1994-10-01 00:00:00
abstract：:The aim was to study the association between preschool behavioural problems and emotional symptoms in 10- to 12-year-old children. The study was based on the Aarhus Birth cohort, Denmark, and included 1,336 children. Based on the parent-administered preschool behaviour questionnaire (PBQ), we identified three not mutu...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-010-0128-2
更新日期：2010-10-01 00:00:00
abstract：:The greater burden of illness in youth with co-occurring attention-deficit/hyperactivity disorder (ADHD) and major depressive disorder (MDD) deserves further investigation, specifically regarding the influence of other psychiatric or medical conditions and the pharmacotherapies prescribed. A retrospective cohort desig...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-014-0541-z
更新日期：2015-01-01 00:00:00
abstract：:Child and adolescent inpatient treatment has faced major changes since the year 2000, including shorter inpatient stays and a greater use of psychotropic drugs. This study explored changes and correlates of suicidal threats and suicide acts among inpatients, by comparing Finnish cross-sectional surveys from 2000 to 20...
journal_title：European child & adolescent psychiatry
pub_type： 历史文章,杂志文章
doi：10.1007/s00787-019-01286-9
更新日期：2019-09-01 00:00:00
abstract：OBJECTIVE:To compare the efficacy, safety, and tolerability of olanzapine and quetiapine in adolescents with first episode psychosis. METHOD:Fifty adolescents (age 16 +/- 1.25) with a first episode of psychosis were randomized to quetiapine or olanzapine in a 6-month open label study. Efficacy and side effect scales, ...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00787-009-0749-5
更新日期：2009-07-01 00:00:00
abstract：:Several studies have demonstrated associations between neuropsychiatric disorders, such as attention-deficit/hyperactivity disorder (ADHD), and the immune system, including autoimmune diseases. Since ADHD and many autoimmune diseases show sex-specific properties, such associations may also differ by sex. Using Norwegi...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-017-1056-1
更新日期：2018-05-01 00:00:00
abstract：:In recent years, there has been a rising interest in the mental health of unaccompanied minor refugees (UMR), who are a high-risk group for mental disorders. Especially the investigation of predictive factors of the mental health of young refugees has received increasing attention. However, there has been no review on...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章,评审
doi：10.1007/s00787-020-01678-2
更新日期：2020-11-09 00:00:00
abstract：:Research consistently chronicles a variety of mental health difficulties that plague institutionally reared children, including attention-deficit/hyperactivity disorder (ADHD), even if not all institutionalized children evince such problems. In seeking to extend work in this area, this research on gene × environment (...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-016-0890-x
更新日期：2017-03-01 00:00:00
abstract：:Service comparison is a policy priority but is not without controversy. This paper aims to investigate the amount of service-level variation in outcomes in child mental health, whether it differed when examining outcomes unadjusted vs. adjusted for expected change over time, and which patient-level characteristics wer...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-016-0939-x
更新日期：2017-06-01 00:00:00
abstract：:Anorexia nervosa (AN) and bulimia nervosa (BN) are complex disorders characterized by disordered eating behavior where the patient's attitude towards weight and shape, as well as their perception of body shape, are disturbed. Formal genetic studies on twins and families suggested a substantial genetic influence for AN...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章,评审
doi：10.1007/s00787-009-0085-9
更新日期：2010-03-01 00:00:00
abstract：OBJECTIVE:This study evaluated the differences in suicidal behaviour between adolescent anorexia nervosa (AN) and bulimia nervosa (BN), and the association of age, menarche timing, duration of eating disorder (ED), depression and general psychopathological symptoms (GSI) with suicidal behaviour in adolescent ED. METHO...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-005-0473-8
更新日期：2005-08-01 00:00:00
abstract：:Alterations in fear learning/generalization are considered to be relevant mechanisms engendering the development of anxiety disorders being the most prevalent mental disorders. Although anxiety disorders almost exclusively have their first onset in childhood and adolescence, etiological research focuses on adult indiv...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-019-01458-7
更新日期：2020-09-01 00:00:00
abstract：BACKGROUND:Given the dosing limitations of methylphenidate short-acting preparations in treating ADHD, galenics with longer release of the substance were developed mainly to avoid drug intake during school hours. OBJECTIVES:This investigation was conducted to assess the efficacy and the duration of action of a new ext...
journal_title：European child & adolescent psychiatry
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1007/s00787-004-1009-3
更新日期：2004-01-01 00:00:00
abstract：:Secular trends in the criminal activity of conduct disordered adolescents admitted as psychiatric in-patients in Norway were examined. A nationwide sample of 650 adolescents hospitalised with DSM-IV Conduct Disorder during the years 1963-1990 was followed up 12-33 years after index hospitalisation by register linkage ...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-005-0444-0
更新日期：2005-07-01 00:00:00
abstract：:It was examined how juvenile psychiatric disorders and adult schizotypal symptoms are associated. 731 patients of the Department of Child and Adolescent Psychiatry of the University Medical Centre Utrecht, the Netherlands, with mean age of 12.1 years (SD = 4.0) were reassessed at the mean age of 27.9 years (SD = 5.7) ...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-013-0409-7
更新日期：2013-11-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:To examine and compare the psychometric properties of two short screening instruments for children and adolescents suffering from attention deficit-/ hyperactivity disorder (ADHD). The Conners' Hyperactivity Index consists of ten items that assess symptoms of hyperactivity through self-report a...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-008-1012-1
更新日期：2008-12-01 00:00:00
abstract：:Children with infantile autism and children with a specific receptive language disorder often show similar behavioural problems, making the differentiation between these two diagnostic categories difficult. The purpose of this study is to evaluate the usefulness of parental information in the differential diagnosis of...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s007870170014
更新日期：2001-12-01 00:00:00
abstract：:Higher levels of anger expression, as well as lower levels of anger control, have been reported for adults with anxiety disorders compared to individuals without anxiety disorders. Different to the research on adults, very few studies examined the relationship between anxiety and anger in childhood. In our study, we i...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-020-01543-2
更新日期：2020-05-07 00:00:00
abstract：:The aims of this study were, firstly, to study the association between parents' and teachers' ratings for the Finnish version of the Autism Spectrum Screening Questionnaire (ASSQ), secondly, to find out whether the original cut-off scores of the ASSQ identify primary school-aged children with Asperger syndrome (AS) or...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-009-0044-5
更新日期：2009-08-01 00:00:00
abstract：:Understanding the developmental course of all health issues associated with preterm birth is important from an individual, clinical and public health point-of-view. Both the number of preterm births and proportion of survivors have increased steadily in recent years. The UK Millennium Cohort Study (n = 18,818) was use...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-016-0872-z
更新日期：2017-01-01 00:00:00
abstract：:The aim of this study is to investigate whether in addition to established early risk factors other, less studied pre-, peri-, and postnatal influences, like gestational hypertension or neonatal respiratory disorders and infections, may increase a child's risk of developing attention-deficit/hyperactivity disorders (A...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章,多中心研究
doi：10.1007/s00787-017-0966-2
更新日期：2017-08-01 00:00:00
abstract：OBJECTIVE:The aim of the study was to investigate capacity, demographic composition, and patterns of practice of Dutch child and adolescent psychiatrists, and to compare these findings with the results of a similar investigation in 1996. METHOD:A postal survey was sent out to all Dutch child and adolescent psychiatris...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-005-0480-9
更新日期：2005-09-01 00:00:00
abstract：:The network approach suggests that psychopathology arises from complex associations between symptoms and may offer insight into the mechanisms that underpin psychiatric comorbidities. The transition from childhood to adolescence is a key period in the development of psychopathology, yet has rarely been considered from...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-018-1128-x
更新日期：2018-11-01 00:00:00
abstract：BACKGROUND:This study aims to examine a) the prevalence of psychosocial problems and b) the association between parent-reported problems and the identification by doctors and nurses (child health professionals, CHP) working in preventive child health care, among immigrant and non-immigrant children. METHODS:CHPs exami...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-005-0454-y
更新日期：2005-05-01 00:00:00
abstract：:Infant mental health problems include difficulties to regulate emotions or attention, crying, sleeping or feeding problems as well as aggressive behavior. Early identifications of these problems help to change developmental trajectories and improve developmental outcomes. Psychiatric assessment and classification have...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章,评审
doi：10.1007/s00787-012-0364-8
更新日期：2013-02-01 00:00:00
abstract：:This study investigated the dietary restraint and depression pathway to loss of control over eating among a sample of overweight youngsters based on the assumptions of the extended cognitive behavioural theory for bulimia nervosa. The children's version of the eating disorder examination interview and the children's d...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-010-0089-5
更新日期：2010-07-01 00:00:00
abstract：:72 child psychiatric and 50 paediatric outpatients were included in a study looking at the Rutter A (2) Scale and the Child Behaviour Checklist (CBCL) completed by mothers. Automated administration with recorded voice as well as visual display of written questions was compared to standard administration: pen and paper...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/BF02084430
更新日期：1992-01-01 00:00:00
