Bird song: superfast muscles control dove's trill.

abstract：:Epidermal growth factor (EGF) and transforming growth factor type I (TGF) are polypeptides of 53 and 50 amino acid residues, respectively. Both bind to EGF receptor, a 1,200-residue transmembranous glycoprotein, leading to phosphorylation of the receptor, enhancement of its tyrosine-specific kinase activity and ultima...

journal_title：Nature

authors： Brown JP,Twardzik DR,Marquardt H,Todaro GJ

更新日期：1985-02-07 00:00:00

abstract：:As oligodendrocytes wrap axons of the central nervous system (CNS) with insulating myelin sheaths, sodium channels that are initially continuously distributed along axons become segregated into regularly spaced gaps in the myelin called nodes of Ranvier. It is not known whether the regular spacing of nodes results fro...

journal_title：Nature

authors： Kaplan MR,Meyer-Franke A,Lambert S,Bennett V,Duncan ID,Levinson SR,Barres BA

更新日期：1997-04-17 00:00:00

abstract：:Humans are colour-blind at night, and it has been assumed that this is true of all animals. But colour vision is as useful for discriminating objects at night as it is during the day. Here we show, through behavioural experiments, that the nocturnal hawkmoth Deilephila elpenor uses colour vision to discriminate colour...

journal_title：Nature

authors： Kelber A,Balkenius A,Warrant EJ

更新日期：2002-10-31 00:00:00

abstract：:Human T-cell receptors for antigen and major histocompatibility complex (MHC) determinants have now been defined on inducer, suppressor, and class 1 and class 2 MHC-specific cytotoxic T lymphocytes as T3-associated clonotypic molecules (Ti) of relative molecular mass 90,000 (90K) composed of one 49-54K alpha- and one ...

journal_title：Nature

authors： Fabbi M,Acuto O,Smart JE,Reinherz EL

更新日期：1984-11-15 00:00:00

abstract：:Fast radio bursts are mysterious millisecond-duration transients prevalent in the radio sky. Rapid accumulation of data in recent years has facilitated an understanding of the underlying physical mechanisms of these events. Knowledge gained from the neighbouring fields of gamma-ray bursts and radio pulsars has also of...

journal_title：Nature

authors： Zhang B

更新日期：2020-11-01 00:00:00

abstract：:The complement system is a key part of the innate immune system, and is required for clearance of pathogens from the bloodstream. After exposure to pathogens, the third component of the complement system, C3, is cleaved to C3b which, after recruitment of factor B, initiates formation of the alternative pathway convert...

journal_title：Nature

authors： Wiesmann C,Katschke KJ,Yin J,Helmy KY,Steffek M,Fairbrother WJ,McCallum SA,Embuscado L,DeForge L,Hass PE,van Lookeren Campagne M

更新日期：2006-11-09 00:00:00

abstract：:Simple mathematical models of the transmission dynamics of HIV that incorporate demographic and epidemiological processes to assess the potential impact of AIDS on human population growth and structure in developing countries suggest that AIDS is capable of changing population growth rates from positive to negative va...

journal_title：Nature

authors： Anderson RM,May RM,McLean AR

更新日期：1988-03-17 00:00:00

abstract：:High-harmonic generation is a well-known method of producing coherent extreme-ultraviolet (EUV) light, with photon energies up to about 0.5 keV (refs 1, 2). This is achieved by focusing a femtosecond laser into a gas, and high harmonics of the fundamental laser frequency are radiated in the forward direction. However,...

journal_title：Nature

authors： Paul A,Bartels RA,Tobey R,Green H,Weiman S,Christov IP,Murnane MM,Kapteyn HC,Backus S

更新日期：2003-01-02 00:00:00

abstract：:Topological physics relies on the structure of the eigenstates of the Hamiltonians. The geometry of the eigenstates is encoded in the quantum geometric tensor1-comprising the Berry curvature2 (crucial for topological matter)3 and the quantum metric4, which defines the distance between the eigenstates. Knowledge of the...

journal_title：Nature

authors： Gianfrate A,Bleu O,Dominici L,Ardizzone V,De Giorgi M,Ballarini D,Lerario G,West KW,Pfeiffer LN,Solnyshkov DD,Sanvitto D,Malpuech G

更新日期：2020-02-01 00:00:00

abstract：:The macronutrient phosphorus is thought to limit primary productivity in the oceans on geological timescales. Although there has been a sustained effort to reconstruct the dynamics of the phosphorus cycle over the past 3.5 billion years, it remains uncertain whether phosphorus limitation persisted throughout Earth's h...

journal_title：Nature

authors： Reinhard CT,Planavsky NJ,Gill BC,Ozaki K,Robbins LJ,Lyons TW,Fischer WW,Wang C,Cole DB,Konhauser KO

更新日期：2017-01-19 00:00:00

abstract：:Mutations or amplification of the MET proto-oncogene are involved in the pathogenesis of several tumours, which rely on the constitutive engagement of this pathway for their growth and survival. However, MET is expressed not only by cancer cells but also by tumour-associated stromal cells, although its precise role in...

journal_title：Nature

authors： Finisguerra V,Di Conza G,Di Matteo M,Serneels J,Costa S,Thompson AA,Wauters E,Walmsley S,Prenen H,Granot Z,Casazza A,Mazzone M

更新日期：2015-06-18 00:00:00

abstract：:In response to environmental cues that promote IP3 (inositol 1,4,5-trisphosphate) generation, IP3 receptors (IP3Rs) located on the endoplasmic reticulum allow the 'quasisynaptical' feeding of calcium to the mitochondria to promote oxidative phosphorylation. However, persistent Ca2+ release results in mitochondrial Ca2...

journal_title：Nature

authors： Kuchay S,Giorgi C,Simoneschi D,Pagan J,Missiroli S,Saraf A,Florens L,Washburn MP,Collazo-Lorduy A,Castillo-Martin M,Cordon-Cardo C,Sebti SM,Pinton P,Pagano M

更新日期：2017-06-22 00:00:00

abstract：:Inositol trisphosphate is a second messenger that controls many cellular processes by generating internal calcium signals. It operates through receptors whose molecular and physiological properties closely resemble the calcium-mobilizing ryanodine receptors of muscle. This family of intracellular calcium channels disp...

journal_title：Nature

authors： Berridge MJ

更新日期：1993-01-28 00:00:00

abstract：:Signal sequences target proteins for secretion from cells or for integration into cell membranes. As nascent proteins emerge from the ribosome, signal sequences are recognized by the signal recognition particle (SRP), which subsequently associates with its receptor (SR). In this complex, the SRP and SR stimulate each ...

journal_title：Nature

authors： Egea PF,Shan SO,Napetschnig J,Savage DF,Walter P,Stroud RM

更新日期：2004-01-15 00:00:00

abstract：:Age-related macular degeneration (AMD), a leading cause of blindness worldwide, is as prevalent as cancer in industrialized nations. Most blindness in AMD results from invasion of the retina by choroidal neovascularisation (CNV). Here we show that the eosinophil/mast cell chemokine receptor CCR3 is specifically expres...

journal_title：Nature

authors： Takeda A,Baffi JZ,Kleinman ME,Cho WG,Nozaki M,Yamada K,Kaneko H,Albuquerque RJ,Dridi S,Saito K,Raisler BJ,Budd SJ,Geisen P,Munitz A,Ambati BK,Green MG,Ishibashi T,Wright JD,Humbles AA,Gerard CJ,Ogura Y,Pan Y,S

更新日期：2009-07-09 00:00:00

abstract：:In response to adenosine 5'-diphosphate, the P2Y1 receptor (P2Y1R) facilitates platelet aggregation, and thus serves as an important antithrombotic drug target. Here we report the crystal structures of the human P2Y1R in complex with a nucleotide antagonist MRS2500 at 2.7 Å resolution, and with a non-nucleotide antago...

journal_title：Nature

authors： Zhang D,Gao ZG,Zhang K,Kiselev E,Crane S,Wang J,Paoletta S,Yi C,Ma L,Zhang W,Han GW,Liu H,Cherezov V,Katritch V,Jiang H,Stevens RC,Jacobson KA,Zhao Q,Wu B

更新日期：2015-04-16 00:00:00

abstract：: ...

journal_title：Nature

authors：

更新日期：2018-11-01 00:00:00

abstract：:An Amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Nature

authors： Schwörer S,Becker F,Feller C,Baig AH,Köber U,Henze H,Kraus JM,Xin B,Lechel A,Lipka DB,Varghese CS,Schmidt M,Rohs R,Aebersold R,Medina KL,Kestler HA,Neri F,von Maltzahn J,Tümpel S,Rudolph KL

更新日期：2019-08-01 00:00:00

abstract：: ...

journal_title：Nature

authors：

更新日期：2018-11-01 00:00:00

abstract：:Progress in the fabrication of nanometre-scale electronic devices is opening new opportunities to uncover deeper aspects of the Kondo effect--a characteristic phenomenon in the physics of strongly correlated electrons. Artificial single-impurity Kondo systems have been realized in various nanostructures, including sem...

journal_title：Nature

authors： Jarillo-Herrero P,Kong J,van der Zant HS,Dekker C,Kouwenhoven LP,De Franceschi S

更新日期：2005-03-24 00:00:00

abstract：:Large panels of comprehensively characterized human cancer models, including the Cancer Cell Line Encyclopedia (CCLE), have provided a rigorous framework with which to study genetic variants, candidate targets, and small-molecule and biological therapeutics and to identify new marker-driven cancer dependencies. To imp...

journal_title：Nature

authors： Ghandi M,Huang FW,Jané-Valbuena J,Kryukov GV,Lo CC,McDonald ER 3rd,Barretina J,Gelfand ET,Bielski CM,Li H,Hu K,Andreev-Drakhlin AY,Kim J,Hess JM,Haas BJ,Aguet F,Weir BA,Rothberg MV,Paolella BR,Lawrence MS,Akbani R

更新日期：2019-05-01 00:00:00

abstract：:Recombination is the exchange of information between two homologous chromosomes during meiosis. The rate of recombination per nucleotide, which profoundly affects the evolution of chromosomal segments, is calculated by comparing genetic and physical maps. Human physical maps have been constructed using cytogenetics, o...

journal_title：Nature

authors： Yu A,Zhao C,Fan Y,Jang W,Mungall AJ,Deloukas P,Olsen A,Doggett NA,Ghebranious N,Broman KW,Weber JL

更新日期：2001-02-15 00:00:00

abstract：:Microscopic diamond was recently discovered in oxidized acid residues from several carbonaceous chondrite meteorites (for example, the C delta component of the Allende meteorite). Some of the reported properties of C delta seem in conflict with those expected of diamond. Here we present high spatial resolution analy...

journal_title：Nature

authors： Blake DF,Freund F,Krishnan KF,Echer CJ,Shipp R,Bunch TE,Tielens AG,Lipari RJ,Hetherington CJ,Chang S

更新日期：1988-04-14 00:00:00

abstract：:The murine cardioviruses, such as the Mengo and encephalomyocarditis viruses, and the bovine aphthoviruses, such as foot-and-mouth disease virus, are distinguished among positive-strand RNA viruses by the presence of long homopolymeric poly(C) tracts within their 5' noncoding sequences. Although the specific lengths (...

journal_title：Nature

authors： Duke GM,Osorio JE,Palmenberg AC

更新日期：1990-02-01 00:00:00

abstract：:Wolbachia is a common maternally inherited bacterial symbiont able to induce crossing sterilities known as cytoplasmic incompatibility (CI) in insects. Wolbachia-modified sperm are unable to complete fertilization of uninfected ova, but a rescue function allows infected eggs to develop normally. By providing a reprodu...

journal_title：Nature

authors： Sinkins SP,Walker T,Lynd AR,Steven AR,Makepeace BL,Godfray HC,Parkhill J

更新日期：2005-07-14 00:00:00

abstract：:The modern giant sperm whale Physeter macrocephalus, one of the largest known predators, preys upon cephalopods at great depths. Lacking a functional upper dentition, it relies on suction for catching its prey; in contrast, several smaller Miocene sperm whales (Physeteroidea) have been interpreted as raptorial (versus...

journal_title：Nature

authors： Lambert O,Bianucci G,Post K,de Muizon C,Salas-Gismondi R,Urbina M,Reumer J

更新日期：2010-07-01 00:00:00

abstract：:Angiotensin II is an important effector molecule controlling blood pressure and volume in the cardiovascular system. Its importance is manifested by the efficacy of angiotensin-converting enzyme inhibitors in the treatment of hypertension and congestive heart failure. Angiotensin II interacts with two pharmacologicall...

journal_title：Nature

authors： Murphy TJ,Alexander RW,Griendling KK,Runge MS,Bernstein KE

更新日期：1991-05-16 00:00:00

abstract：:Heterotrimeric G-proteins bind to cell-surface receptors and are integral in transmission of signals from outside the cell. Upon activation of the Galpha subunit by binding of GTP, the Galpha and Gbetagamma subunits dissociate and interact with effector proteins for signal transduction. Regulatory proteins with the 19...

journal_title：Nature

authors： Kimple RJ,Kimple ME,Betts L,Sondek J,Siderovski DP

更新日期：2002-04-25 00:00:00

abstract：:A DNA probe from a human Y chromosome-derived cosmid detects a single-copy genomic DNA fragment which can appear in different allelic forms shared by both sex chromosomes. Variants at this DNA locus show an autosomal pattern of inheritance, undergo recombination with sexual phenotype and can therefore be described as ...

journal_title：Nature

authors： Simmler MC,Rouyer F,Vergnaud G,Nyström-Lahti M,Ngo KY,de la Chapelle A,Weissenbach J

更新日期：1985-10-24 00:00:00

abstract：: ...

journal_title：Nature

authors： Beekes M,Mielke M,Thomzig A

更新日期：2019-01-01 00:00:00