Abstract:
:We present a www server for AUGUSTUS, a novel software program for ab initio gene prediction in eukaryotic genomic sequences. Our method is based on a generalized Hidden Markov Model with a new method for modeling the intron length distribution. This method allows approximation of the true intron length distribution more accurately than do existing programs. For genomic sequence data from human and Drosophila melanogaster, the accuracy of AUGUSTUS is superior to existing gene-finding approaches. The advantage of our program becomes apparent especially for larger input sequences containing more than one gene. The server is available at http://augustus.gobics.de.
journal_name
Nucleic Acids Resjournal_title
Nucleic acids researchauthors
Stanke M,Steinkamp R,Waack S,Morgenstern Bdoi
10.1093/nar/gkh379keywords:
subject
Has Abstractpub_date
2004-07-01 00:00:00pages
W309-12issue
Web Server issueeissn
0305-1048issn
1362-4962pii
32/suppl_2/W309journal_volume
32pub_type
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