Abstract：
:Approximately 15 million Americans including over 5 million children suffer from asthma, the most common chronic disease in childhood. The prevalence of pediatric asthma has risen sharply over the past four decades, with the sharpest increases occurring in children younger than 6 years and in urban, predominantly minority, populations. The reasons for this dramatic increase are not yet clear. Recent epidemiological studies indicate a higher prevalence of dietary antioxidant deficiency among asthmatics patients. However, the results of these studies are inconsistent or even contradictory. Epidemiological studies with robust design and use of novel epidemiological tools are urgently needed to examine the impact of dietary antioxidants on the incidence of asthma in preschool children. An incidence density case-control study which includes non-atopic controls, who are matched for age, gender, race, study center and sampling time to each asthmatic case will offer a robust study design. A validated food frequency questionnaire and an asthma and atopy severity score can be used to interview the parents of the recruited children. Risk set sampling may enable us to explore possible associations between the type and quantity of dietary antioxidants and the development and severity of asthma in such an epidemiological study.
journal_name
Med Hypothesesjournal_title
Medical hypothesesauthors
Kalantar-Zadeh K,Lee GH,Block Gdoi
10.1016/j.mehy.2003.10.001keywords:
subject
Has Abstractpub_date
2004-01-01 00:00:00pages
280-90issue
2eissn
0306-9877issn
1532-2777pii
S0306987703003360journal_volume
62pub_type
杂志文章abstract：:It has been shown by Elmets et al. (1) that ultraviolet irradiation of the skin followed by the application of a normally sensitizing antigen results in tolerance induction to the antigen. This tolerance is due to the induction of suppressor T-cells specific for the antigen. Multiple sclerosis is more common in certai...
journal_title：Medical hypotheses
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journal_title：Medical hypotheses
pub_type： 社论
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更新日期：2008-09-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章
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更新日期：2011-02-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章
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更新日期：2013-08-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章,评审
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journal_title：Medical hypotheses
pub_type： 杂志文章
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更新日期：2011-04-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/s0306-9877(96)90226-1
更新日期：1996-01-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章
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更新日期：2002-10-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2006.12.051
更新日期：2007-01-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1054/mehy.1997.0655
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journal_title：Medical hypotheses
pub_type： 杂志文章
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pub_type： 杂志文章
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journal_title：Medical hypotheses
pub_type： 杂志文章,评审
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journal_title：Medical hypotheses
pub_type： 杂志文章
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更新日期：2001-02-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章
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更新日期：2005-01-01 00:00:00
abstract：:A recent published model described the phenomenon of a global panic reaction (GPR) on the stock markets based on two remarkable stock market crashes in the months of January and March [Sperling W, Bleich S, Reulbach U, Black Monday on stock markets throughout the world - a new phenomenon of collective panic disorder? ...
journal_title：Medical hypotheses
pub_type： 杂志文章
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更新日期：2009-11-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章
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journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1054/mehy.2000.1247
更新日期：2001-04-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章
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更新日期：2017-05-01 00:00:00
