Abstract:
:A 53-year-old woman was found to have a tumor in the pineal region. Histologically, Homer-Wright rosettes were sporadically distributed in a diffuse proliferation of round tumor cells that were immunoreactive for synaptophysin and chromogranin. A few perivascular pseudorosettes were also present, and the perivascular tumor cells were immunoreactive for glial fibrillary acidic protein and vimentin. By electron microscopy, well-developed junctions and pronounced interdigitation of abutting plasma membranes were noted in many tumor cells, as well as abundant intracytoplasmic microtubules. These findings indicated that the tumor was a pineal parenchymal tumor accompanied by an extraordinary epithelial-like differentiation, suggesting retinoblastic photoreceptor cell differentiation.
journal_name
Brain Tumor Patholjournal_title
Brain tumor pathologyauthors
Utsuki S,Kawano N,Oka H,Fukushima Y,Kondo K,Tanizaki Y,Yashui Y,Fujii K,Yagishita Sdoi
10.1007/BF02478945keywords:
subject
Has Abstractpub_date
2003-01-01 00:00:00pages
33-7issue
1eissn
1433-7398issn
1861-387Xjournal_volume
20pub_type
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