Permeability of bacterial spores. II. Molecular variables affecting solute permeation.

Abstract:

:Gerhardt, Philipp (University of Michigan, Ann Arbor) and S. H. Black. Permeability of bacterial spores. II. Molecular variables affecting solute permeation. J. Bacteriol. 82:750-760. 1961.-More than 100 compounds were tested for their uptake by dormant spores of a bacillus. The extent of penetration was found to be dependent on at least three molecular properties: (i) The dissociation of electrolytes usually resulted in high or low uptake predictable from their charge. (ii) Lipid insolubility restricted permeation of small molecules. (iii) The molecular weight of unsubstituted glycol and sugar polymers exponentially limited penetration to eventual exclusion at mol wt above 160,000. The results were plotted as a generalized curve, calculations from which permitted an interpretation that the effective spore surface contains pores varying in diameter from 10 to 200 A.

journal_name

J Bacteriol

journal_title

Journal of bacteriology

authors

GERHARDT P,BLACK SH

doi

10.1128/JB.82.5.750-760.1961

keywords:

subject

Has Abstract

pub_date

1961-11-01 00:00:00

pages

750-60

eissn

0021-9193

issn

1098-5530

journal_volume

82

pub_type

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