Evolution of blood magnesium, sodium and potassium in depressed patients followed for three months.

Abstract:

:No consensus has been obtained about blood electrolyte status, especially about magnesium, in affective disorders. This is mainly due to the lack of information about the distribution of the patients in clinical subgroups, sex, type of treatment and about the severity of their illnesses. Most of these studies concerned treated patients. We confirmed in this study that drug-free depressed patients have higher erythrocyte and plasma magnesium than controls, as shown in previous reports. Significant differences are observed in as shown in previous reports. Significant differences are observed in patients for sex and between clinical subgroups. Low plasma potassium levels are described in both male and female depressed patients. The erythrocyte magnesium level tends to normalize in parallel with clinical improvement, depending on sex and clinical subgroup, and seems then to be related to the intensity of the depression. Plasma magnesium in male and female patients, except for female unipolars, remains higher than controls in all conditions and might be related to the diagnosis of affective disorders.

journal_name

Neuropsychobiology

journal_title

Neuropsychobiology

authors

Widmer J,Bovier P,Karege F,Raffin Y,Hilleret H,Gaillard JM,Tissot R

doi

10.1159/000118914

keywords:

subject

Has Abstract

pub_date

1992-01-01 00:00:00

pages

173-9

issue

4

eissn

0302-282X

issn

1423-0224

pii

118914

journal_volume

26

pub_type

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