Implementation of Gy-Eq for deterministic effects limitation in shield design.

abstract：:Development of a curative local treatment for large hepatocellular carcinoma (HCC) is an important issue. Here, we investigated the dose homogeneity, safety and antitumor effectiveness of proton beam therapy (PBT) using a patch-field technique for large HCC. Data from nine patients (aged 52-79 years) with large HCC tr...

journal_title：Journal of radiation research

authors： Nakamura M,Fukumitsu N,Kamizawa S,Numajiri H,Nemoto Murofushi K,Ohnishi K,Aihara T,Ishikawa H,Okumura T,Tsuboi K,Sakurai H

更新日期：2018-09-01 00:00:00

abstract：:The aim of the study was to compare clinical outcomes and toxicity between 3D conformal radiotherapy (3DCRT) and image-guided intensity-modulated radiotherapy (IG-IMRT) administered through helical tomotherapy in locally advanced rectal cancer (LARC) patients receiving preoperative chemoradiotherapy. We reviewed 144 p...

journal_title：Journal of radiation research

authors： Huang CM,Huang MY,Tsai HL,Huang CW,Ma CJ,Lin CH,Huang CJ,Wang JY

更新日期：2017-03-01 00:00:00

abstract：:The study aimed to detect features of human serum proteome that were associated with exposure to ionizing radiation. The analyzed group consisted of 46 patients treated with radical radiotherapy for larynx cancer; patients were irradiated with total doses in a range from 51 to 72 Gy. Three consecutive blood samples we...

journal_title：Journal of radiation research

authors： Widłak P,Pietrowska M,Wojtkiewicz K,Rutkowski T,Wygoda A,Marczak L,Marczyk M,Polańska J,Walaszczyk A,Domińczyk I,Składowski K,Stobiecki M,Polański A

更新日期：2011-01-01 00:00:00

abstract：:Hyper-radiosensitivity (HRS) is a well-known bioresponse under low-dose or low-dose-rate exposures. Although disorder of the DNA repair function, non-targeted effects and accumulation of cells in G2 have been experimentally observed, the mechanism for inducing HRS by long-term irradiation is still unclear. On the basi...

journal_title：Journal of radiation research

authors： Matsuya Y,Tsutsumi K,Sasaki K,Yoshii Y,Kimura T,Date H

更新日期：2017-05-01 00:00:00

abstract：:This study investigated the radioprotective effect of Sipunculus nudus L. polysaccharide (SNP) in combination with WR-2721, rhIL-11 and rhG-CSF on irradiated mice. A total of 70 Imprinting Control Region (ICR) mice were divided into seven groups: the control group, the model group and five administration groups. All g...

journal_title：Journal of radiation research

authors： Jiang S,Shen X,Liu Y,He Y,Jiang D,Chen W

更新日期：2015-05-01 00:00:00

abstract：:The purpose of this study was to assess the toxicity and efficacy of multimodal approaches, including three-dimensional conformal re-irradiation, for patients with recurrent or persistent esophageal cancer after radiotherapy. Thirty-one patients with esophageal cancer treated with three-dimensional conformal re-irradi...

journal_title：Journal of radiation research

authors： Yamaguchi S,Ohguri T,Imada H,Yahara K,Moon SD,Higure A,Yamaguchi K,Yoshikawa I,Harada M,Korogi Y

更新日期：2011-01-01 00:00:00

abstract：:A photoluminescence glass dosimeter, GD-301, was applied to the measurement of low absorbed doses in mice exposed to low-dose rate 137Cs gamma-rays. The dosimeter system consists of small rod-shaped glass chip detectors capable of embedded in the body of a mouse and an automatic readout device equipped with a standard...

journal_title：Journal of radiation research

authors： Hoshi Y,Nomura T,Oda T,Iwasaki T,Fujita K,Ishikawa T,Kato A,Ikegami T,Sakai K,Tanooka H,Yamada T

更新日期：2000-06-01 00:00:00

abstract：:We investigated the efficacy and safety of albumin-bound paclitaxel (nab-PTX) and carboplatin (CBDCA) with concurrent radiotherapy for unresectable locally advanced non-small-cell lung cancer (NSCLC). Patients with Stage III NSCLC and an Eastern Cooperative Oncology Group performance status of 0 or 1 were eligible. Co...

journal_title：Journal of radiation research

authors： Hasegawa T,Futamura Y,Horiba A,Yoshida T,Suzuki T,Kato T,Kaito D,Ohno Y,Iida T,Hayashi S,Sawa T

更新日期：2016-01-01 00:00:00

abstract：:To gain an insight into the relationship between UVB-carcinogenesis and natural killer activity, we examined ultraviolet light-induced carcinogenesis in mice with high natural killer, activity (KSN) and mice with natural killer deficiency (KSN-bg). We exposed mice six times a week to three levels of daily ultraviolet ...

journal_title：Journal of radiation research

authors： Ishigaki Y,Yasuda K,Hashimoto N,Hayakawa J,Hiai H,Nikaido O

更新日期：1998-06-01 00:00:00

abstract：:The effect of gamma-irradiation on a major nutritional function of the yolk sac (the uptake and digestion of macromolecular materials) was studied in rat visceral yolk sacs cultured in vitro being used 125I-labeled bovine serum albumin (RISA) as the tracer protein. The uptake of RISA (per g wet weight) by rat yolk sac...

journal_title：Journal of radiation research

authors： Takahashi S,Koshimoto C,Kubota Y

更新日期：1993-06-01 00:00:00

abstract：:The yield of OH radical induced by ionizing radiation was estimated by an empirical model; a prescribed diffusion model for a spur of single size applying to neutral water. Two representative spur distances were introduced, one for an incident primary charged particle and one for a representative secondary electron, t...

journal_title：Journal of radiation research

authors： Yamaguchi H,Uchihori Y,Yasuda N,Takada M,Kitamura H

更新日期：2005-09-01 00:00:00

abstract：:Irregular breathing can influence the outcome of 4D computed tomography imaging and cause artifacts. Visual biofeedback systems associated with a patient-specific guiding waveform are known to reduce respiratory irregularities. In Japan, abdomen and chest motion self-control devices (Abches) (representing simpler visu...

journal_title：Journal of radiation research

authors： Nakajima Y,Kadoya N,Kanai T,Ito K,Sato K,Dobashi S,Yamamoto T,Ishikawa Y,Matsushita H,Takeda K,Jingu K

更新日期：2016-07-01 00:00:00

abstract：:Efficacy of different schedules of HDR brachytherapy in concurrent chemoradiotherapy was evaluated. The study compared the effectiveness of the two HDR brachytherapy schedules which have the same Biological Effective Dose (BED) in locally advanced cervical carcinoma that was treated with concurrent chemoradiotherapy. ...

journal_title：Journal of radiation research

authors： Tharavichitkul E,Klunkin P,Lorvidhaya V,Sukthomya V,Chakrabhandu S,Pukanhaphan N,Chitapanarux I,Galalae R

更新日期：2012-01-01 00:00:00

abstract：:This study aimed to evaluate the relationship between cardiac toxicity after definitive chemoradiotherapy (CRT) for esophageal cancer and the dose-volume histogram (DVH) of organs at risk (OARs) [using biological effective dose (BED)]. We analyzed the data of 83 patients with esophageal cancer treated using definitive...

journal_title：Journal of radiation research

authors： Takeuchi Y,Murakami Y,Kameoka T,Ochi M,Imano N,Takahashi I,Nishibuchi I,Kimura T,Kawahara D,Saito A,Nagata Y

更新日期：2020-03-23 00:00:00

abstract：:miR-34a is transcriptionally induced by the tumor suppressor gene p53, which is often downregulated in non-small cell lung cancer (NSCLC). To address whether the downstream signal of miR-34a is sufficient to induce apoptosis and to alter cellular radiosensitivity, a chemical synthetic miR-34a mimic was delivered into ...

journal_title：Journal of radiation research

authors： Duan W,Xu Y,Dong Y,Cao L,Tong J,Zhou X

更新日期：2013-07-01 00:00:00

abstract：:Radiation-induced rescue effect (RIRE) in cells refers to the phenomenon where irradiated cells (IRCs) receive help from feedback signals produced by partnered bystander unirradiated cells (UIRCs) or from the conditioned medium (CM) that has previously conditioned the UIRCs. In the present work, we explored the role o...

journal_title：Journal of radiation research

authors： Pathikonda S,Cheng SH,Yu KN

更新日期：2020-05-22 00:00:00

abstract：:A series of experiments was carried out using female (C57BL/6N x C3H/He)F1 mice (BCF1) to assess the carcinogenic effect of tritiated water (HTO) following a preliminary experiment in which the acute effect of HTO was studied in young female mice of C57BL/6L strain in an attempt to gain basic information on the long-t...

journal_title：Journal of radiation research

authors： Seyama T,Yamamoto O,Kinomura A,Yokoro K

更新日期：1991-12-01 00:00:00

abstract：:The purpose of this study was to quantify the changes of tumor blood flow (BF) in cervical cancer after radiation therapy by using perfusion computed tomography (CT), and to examine the difference between maximum slope (MS) and single-input one-compartment model (SOCM) methods. Fourteen consecutive patients who receiv...

journal_title：Journal of radiation research

authors： Shibuya K,Tsushima Y,Horisoko E,Noda SE,Taketomi-Takahashi A,Ohno T,Amanuma M,Endo K,Nakano T

更新日期：2011-01-01 00:00:00

abstract：:The aim of this study is to evaluate the potential radioprotective effects of N-acetylcysteine (NAC) against genotoxicity and cytotoxicity. The effect of WR-2721, as a representative of clinically used radioprotector, was compared with that of NAC, using the chromosomal aberration (CA) and micronucleus (MN) test syste...

journal_title：Journal of radiation research

authors： Demirel C,Kilçiksiz S,Ay OI,Gürgül S,Ay ME,Erdal N

更新日期：2009-01-01 00:00:00

abstract：:The purpose of this study was to analyze the dosimetry and investigate the clinical outcomes of radiation-induced rib fractures (RIRFs) after stereotactic body radiotherapy (SBRT). A total of 126 patients with Stage I primary lung cancer treated with SBRT, who had undergone follow-up computed tomography (CT) at least ...

journal_title：Journal of radiation research

authors： Miura H,Inoue T,Shiomi H,Oh RJ

更新日期：2015-03-01 00:00:00

abstract：:We evaluated the interrelationship between rectal content and intrafraction motion of the prostate. Forty seven prostate cancer patients instructed to remove their rectal gas were imaged by planning CT and MRI before radiotherapy (RT) and during RT. The total scan time was comparable to our cone-beam CT scanning and t...

journal_title：Journal of radiation research

authors： Ogino I,Kaneko T,Suzuki R,Matsui T,Takebayashi S,Inoue T,Morita S

更新日期：2011-01-01 00:00:00

abstract：:The present paper is part of an attempt at finally reconstructing the realities of nuclear tests and their human effects near Semipalatinsk, Kazakhstan. As a first step, it tries to reconstruct the overall image of nuclear tests and their human effects. Our data are 199 written testimonies of those affected by radiati...

journal_title：Journal of radiation research

authors： Matsuo M,Kawano N,Satoh K,Apsalikov KN,Moldagaliev T

更新日期：2006-02-01 00:00:00

abstract：:The direct biological effects of radiation, particularly accelerated heavy particle ions, on neurons are not fully known. Hence, the direct effect of carbon-ion beams on immature neurons was investigated by comparing to the effect of X-rays in vitro using primary hippocampal neurons. Primary neurons were prepared from...

journal_title：Journal of radiation research

authors： Kaminuma T,Suzuki Y,Shirai K,Mizui T,Noda SE,Yoshida Y,Funayama T,Takahashi T,Kobayashi Y,Shirao T,Nakano T

更新日期：2010-01-01 00:00:00

abstract：:Differentiation-induction therapy is an attractive approach in leukemia treatment. It has been suggested that the accumulation of intracellular reactive oxygen species (ROS) is involved in megakaryocytic differentiation induced by phorbol 12-myristate 13-acetate (PMA) in the K562 leukemia cell line. Therefore, a ROS-i...

journal_title：Journal of radiation research

authors： Hirose K,Monzen S,Sato H,Sato M,Aoki M,Hatayama Y,Kawaguchi H,Narita Y,Takai Y,Kashiwakura I

更新日期：2013-05-01 00:00:00

abstract：:Modern treatment machines have shown small inter-unit variability regarding beam data. Recently, vendor-provided average beam data, such as the Representative Beam Data (RBD) of the TrueBeam (Varian Medical Systems, Palo Alto, CA, USA), has been used for modeling of the Eclipse (Varian Medical Systems) treatment plann...

journal_title：Journal of radiation research

authors： Isono M,Akino Y,Mizuno H,Tanaka Y,Masai N,Yamamoto T

更新日期：2020-03-23 00:00:00

abstract：:In this study, a mechanism in which low-dose hyper-radiosensitivity (HRS) is permanently removed, induced by low-dose-rate (LDR) (0.2-0.3 Gy/h for 1 h) but not by high-dose-rate priming (0.3 Gy at 40 Gy/h) was investigated. One HRS-negative cell line (NHIK 3025) and two HRS-positive cell lines (T-47D, T98G) were used....

journal_title：Journal of radiation research

authors： Edin NJ,Sandvik JA,Vollan HS,Reger K,Görlach A,Pettersen EO

更新日期：2013-11-01 00:00:00

abstract：:In this study, a novel combination treatment of armed oncolytic adenovirus expressing interleukin 12 (IL-12) and granulocyte-macrophage colony-stimulating factor (GM-CSF) with radiation was investigated for antitumor and antimetastatic effect in a murine hepatic cancer (HCa-I) model. Tumor bearing syngeneic mice were ...

journal_title：Journal of radiation research

authors： Kim W,Seong J,Oh HJ,Koom WS,Choi KJ,Yun CO

更新日期：2011-01-01 00:00:00

abstract：:To evaluate the effect of the sympathetic nervous system on radiation-induced apoptosis in jejunal crypt cells, apoptosis levels were compared in spontaneously hypertensive rats (SHR), animals which are a genetic hyperfunction model of the sympathetic nervous system, and normotensive Wistar-Kyoto rats (WKY). SHR and W...

journal_title：Journal of radiation research

authors： Matsuu M,Shichijo K,Nakamura Y,Ikeda Y,Naito S,Ito M,Okaichi K,Sekine I

更新日期：2000-03-01 00:00:00

abstract：:Based on the accumulating evidence for equivalent results of partial-breast irradiation (PBI) and whole-breast irradiation (WBI) in breast-conserving therapy (BCT), the American Society for Radiation Oncology (ASTRO) updated the consensus statement (CS) to expand the range of potential candidates for PBI outside clini...

journal_title：Journal of radiation research

authors： Sato K,Fuchikami H,Takeda N,Kato M,Shimo T,Okawa T

更新日期：2018-05-01 00:00:00

abstract：:We examined the effect of whole body low-dose gamma-irradiation on the status of the antioxidant defense system in the rodent kidneys at different time intervals. Young male Balb/c mice were exposed to whole body radiation from a (60)Co source at doses of 10, 25 and 50 cGy (48.78 cGy/min). Antioxidant status and lipid...

journal_title：Journal of radiation research

authors： Pathak CM,Avti PK,Kumar S,Khanduja KL,Sharma SC

更新日期：2007-03-01 00:00:00