Serum lactate dehydrogenase predicts survival in small-cell lung cancer patients with brain metastases that were treated with whole-brain radiotherapy.

abstract：:Efficacy of different schedules of HDR brachytherapy in concurrent chemoradiotherapy was evaluated. The study compared the effectiveness of the two HDR brachytherapy schedules which have the same Biological Effective Dose (BED) in locally advanced cervical carcinoma that was treated with concurrent chemoradiotherapy. ...

journal_title：Journal of radiation research

authors： Tharavichitkul E,Klunkin P,Lorvidhaya V,Sukthomya V,Chakrabhandu S,Pukanhaphan N,Chitapanarux I,Galalae R

更新日期：2012-01-01 00:00:00

abstract：:In our previous studies, we found that low-dose radiation inhibits oxidative stress-induced diseases due to increased antioxidants. Although these effects of low-dose radiation were demonstrated, further research was needed to clarify the effects. However, the analysis of oxidative stress is challenging, especially th...

journal_title：Journal of radiation research

authors： Kanzaki N,Kataoka T,Etani R,Sasaoka K,Kanagawa A,Yamaoka K

更新日期：2017-01-01 00:00:00

abstract：:Wistar rats inhaled 239PuO2 particles prepared by the calcination of 239Pu hydroxide at 1150 and 400 degrees C. Lung retention, fecal and urinary excretion, and translocation of 239Pu were compared between the two calcination temperatures. The clearance of 239Pu from the lungs was significantly faster in the rats expo...

journal_title：Journal of radiation research

authors： Sato H,Yamada Y,Ishigure N,Nakano T,Enomoto H,Takahashi S,Kubota Y,Inaba J

更新日期：1999-06-01 00:00:00

abstract：:Thermionic emission (TE)-type X-ray generators have been exclusively used in medicine, but there are many difficulties in making these X-ray sources compact. A field emission (FE)-type X-ray generator using carbon nanotubes is a newly-developed compact system that can be as small as several cm in length. Considering t...

journal_title：Journal of radiation research

authors： Nakazato T,Nakanishi M,Kita S,Okuyama F,Shibamoto Y,Otsuka T

更新日期：2007-03-01 00:00:00

abstract：:Disufiram (a drug used for the treatment of alcoholism) protected microsomal membranes and plasmid DNA against damages induced by gamma-radiation. The peroxidation of membrane lipids increased linearly with the radiation dose up to 600 Gy, and the presence of disulfiram inhibited membrane lipid peroxidation as assayed...

journal_title：Journal of radiation research

authors： Gandhi NM,Gopalaswamy UV,Nair Cr

更新日期：2003-09-01 00:00:00

abstract：:Boron Neutron Capture Therapy (BNCT) effectiveness depends on the preferential sequestration of boron in cancer cells relative to normal tissue cells. We present a novel strategy for sequestering boron using an adenovirus expressing the sodium iodide symporter (NIS). Human glioma grown subcutaneously in athymic mice a...

journal_title：Journal of radiation research

authors： Kumar S,Freytag SO,Barton KN,Burmeister J,Joiner MC,Sedghi B,Movsas B,Binns PJ,Kim JH,Brown SL

更新日期：2010-01-01 00:00:00

abstract：:We have proposed four dimensional (4D) digitally reconstructed radiography (DRR) for verifying a lung tumor position during volumetric modulated arc therapy (VMAT). An internal target volume (ITV) was defined based on two clinical target volumes (CTVs) delineated on maximum exhalation and maximum inhalation images acq...

journal_title：Journal of radiation research

authors： Nakagawa K,Kida S,Haga A,Masutani Y,Yamashita H,Onoe T,Imae T,Tanaka K,Ohtomo K,Yoda K

更新日期：2012-07-01 00:00:00

abstract：:The effectiveness of an Electronic Personal Dosemeter (Siemens EPD) for cosmic-radiation dosimetry at aviation altitudes was examined on eight international flights between March and September, 1998. The EPD values (Hepd) of the dose equivalent from penetrating radiation, Hp(10), were assumed to be almost the same as ...

journal_title：Journal of radiation research

authors： Yasuda H,Fujitaka K

更新日期：2001-03-01 00:00:00

abstract：:To identify the repair dynamics involved in high linear energy transfer (LET) radiation-induced DNA damage, phospho-H2AX (gammaH2AX) foci formation was analyzed after cellular exposure to iron ions (Fe-ions, 500 MeV u(-1), 200 KeV microm(-1)). The foci located at DNA damage sites were visualized using immunocytochemic...

journal_title：Journal of radiation research

authors： Takahashi A,Yamakawa N,Kirita T,Omori K,Ishioka N,Furusawa Y,Mori E,Ohnishi K,Ohnishi T

更新日期：2008-11-01 00:00:00

abstract：:The study aimed to detect features of human serum proteome that were associated with exposure to ionizing radiation. The analyzed group consisted of 46 patients treated with radical radiotherapy for larynx cancer; patients were irradiated with total doses in a range from 51 to 72 Gy. Three consecutive blood samples we...

journal_title：Journal of radiation research

authors： Widłak P,Pietrowska M,Wojtkiewicz K,Rutkowski T,Wygoda A,Marczak L,Marczyk M,Polańska J,Walaszczyk A,Domińczyk I,Składowski K,Stobiecki M,Polański A

更新日期：2011-01-01 00:00:00

abstract：:As a part of technical improvements of chromosome aberration analysis on human peripheral lymphocytes for biological radiation dosimetry, we examined the optimal conditions for the use of colcemid in chromosome preparation in order to obtain enough number of cells at metaphase in the first cell division. When treated ...

journal_title：Journal of radiation research

authors： Kanda R,Jiang T,Hayata I,Kobayashi S

更新日期：1994-03-01 00:00:00

abstract：:Although well described in the 1960s, liver toxicity secondary to radiation therapy, commonly known as radiation-induced liver disease (RILD), remains a major challenge. RILD encompasses two distinct clinical entities, a 'classic' form, composed of anicteric hepatomegaly, ascites and elevated alkaline phosphatase; and...

journal_title：Journal of radiation research

authors： Toesca DAS,Ibragimov B,Koong AJ,Xing L,Koong AC,Chang DT

更新日期：2018-03-01 00:00:00

abstract：:The aim of the study was to evaluate inter-fractional dosimetric variations for high-dose rate breast brachytherapy using a strut-adjusted volume implant (SAVI). For the nine patients included, dosimetric constraints for treatment were as follows: for the planning target volume for evaluation (PTV_Eval), the volume re...

journal_title：Journal of radiation research

authors： Iijima K,Okamoto H,Takahashi K,Aikawa A,Wakita A,Nakamura S,Nishioka S,Harada K,Notake R,Sugawara A,Yoshimura R,Kunieda E,Itami J

更新日期：2020-01-23 00:00:00

abstract：:Neutron dose is transferred to biological materials through the recoil protons produced by elastic scattering. When a low-velocity proton collides with the atoms or molecules of a target, it changes to a hydrogen atom by electron capture; this hydrogen atom then changes to a proton by losing the electron. Because the ...

journal_title：Journal of radiation research

authors： Endo S

更新日期：2004-09-01 00:00:00

abstract：:There is an urgent need to develop non-toxic radioprotectors. We tested the efficacy of a 3-drug combination (3-DC) of iloprost, misoprostol, and 3D-MPL (3-deacylated monophosphoryl lipid A) and the effects of postirradiation clinical support with high doses of antibiotics and blood transfusion. Canines were given 3-D...

journal_title：Journal of radiation research

authors： Kumar KS,Srinivasan V,Toles RE,Miner VL,Jackson WE,Seed TM

更新日期：2002-12-01 00:00:00

abstract：:The quality of the sublethal damage (SLD) after irradiation with high-linear energy transfer (LET) ion beams was investigated with low-LET photons. Chinese hamster V79 cells and human squamous carcinoma SAS cells were first exposed to a priming dose of different ion beams at different LETs at the Heavy Ion Medical Acc...

journal_title：Journal of radiation research

authors： Furusawa Y,Nakano-Aoki M,Matsumoto Y,Hirayama R,Kobayashi A,Konishi T

更新日期：2017-11-01 00:00:00

abstract：:Ionizing radiation induces biological effects not only in irradiated cells but also in non-irradiated cells, which is called the bystander effect. Recently, in vivo and in vitro experiments have suggested that both gap junction hemichannel connexin43 (Cx43) and extracellular adenosine triphosphate (ATP) released from ...

journal_title：Journal of radiation research

authors： Ohshima Y,Tsukimoto M,Harada H,Kojima S

更新日期：2012-07-01 00:00:00

abstract：:Inoue and Iwakura recently reported that the specific activity ratio of organically-bound 3H to free water 3H in polished rice samples collected in Japan and China was lower than unity. Their paper was the first to report the systematic apparent elimination of 3H for incorporation to organically-bound form in samples ...

journal_title：Journal of radiation research

authors： Hisamatsu S,Katsumata T,Takizawa Y

更新日期：1991-12-01 00:00:00

abstract：:An overview is given of the dose-response relationship for stable chromosome aberrations (i.e., translocations and inversions) in the peripheral blood lymphocytes of A-bomb survivors in Hiroshima. Special emphasis is placed on (i) the overdispersion of survivor cases with either unexpectedly high or low aberration fre...

journal_title：Journal of radiation research

authors： Awa AA,Nakano M,Ohtaki K,Kodama Y,Lucas J,Gray J

更新日期：1992-03-01 00:00:00

abstract：:This study aimed to evaluate the relationship between cardiac toxicity after definitive chemoradiotherapy (CRT) for esophageal cancer and the dose-volume histogram (DVH) of organs at risk (OARs) [using biological effective dose (BED)]. We analyzed the data of 83 patients with esophageal cancer treated using definitive...

journal_title：Journal of radiation research

authors： Takeuchi Y,Murakami Y,Kameoka T,Ochi M,Imano N,Takahashi I,Nishibuchi I,Kimura T,Kawahara D,Saito A,Nagata Y

更新日期：2020-03-23 00:00:00

abstract：:The biokinetics of radon in the body has previously been studied with the assumption that its absorption through the skin is negligibly small. This assumption would be acceptable except in specific situations, such as bathing in a radon hot spring where the radon concentration in thermal water is far higher than that ...

journal_title：Journal of radiation research

authors： Sakoda A,Ishimori Y,Tschiersch J

更新日期：2016-07-01 00:00:00

abstract：:Alzheimer's disease (AD) is the most common progressive and irreversible neurodegenerative disease and it is caused by neuronal death in the brain. Recent studies have shown that non-ionizing radiofrequency (RF) radiation has some beneficial cognitive effects in animal models of AD. In this study, we examined the effe...

journal_title：Journal of radiation research

authors： Lee JS,Kim JY,Kim HJ,Kim JC,Lee JS,Kim N,Park MJ

更新日期：2016-11-01 00:00:00

abstract：:In this study, a mechanism in which low-dose hyper-radiosensitivity (HRS) is permanently removed, induced by low-dose-rate (LDR) (0.2-0.3 Gy/h for 1 h) but not by high-dose-rate priming (0.3 Gy at 40 Gy/h) was investigated. One HRS-negative cell line (NHIK 3025) and two HRS-positive cell lines (T-47D, T98G) were used....

journal_title：Journal of radiation research

authors： Edin NJ,Sandvik JA,Vollan HS,Reger K,Görlach A,Pettersen EO

更新日期：2013-11-01 00:00:00

abstract：:The radioprotective effect of hawthorn (Crataegus microphylla) fruit extract against genotoxicity induced by gamma irradiation has been investigated in mouse bone marrow cells. A single intraperitoneal (ip) administration of hawthorn extract at doses of 25, 50, 100 and 200 mg/kg 1h prior to gamma irradiation (2 Gy) re...

journal_title：Journal of radiation research

authors： Hosseinimehr SJ,Azadbakht M,Mousavi SM,Mahmoudzadeh A,Akhlaghpoor S

更新日期：2007-01-01 00:00:00

abstract：:Previous studies have demonstrated that X-ray irradiation affects angiogenesis in tumors. Here, we studied the effects of gamma-ray irradiation on boron-10 compound accumulation in a murine tumor model. The mouse squamous cell carcinoma was irradiated with gamma-ray before BSH ((10)B-enriched borocaptate sodium) admin...

journal_title：Journal of radiation research

authors： Liu Y,Nagata K,Masunaga S,Suzuki M,Kashino G,Kinashi Y,Tanaka H,Sakurai Y,Maruhashi A,Ono K

更新日期：2009-11-01 00:00:00

abstract：:To evaluate the feasibility of using radiosensitivity of peripheral leukocytes as a predictor of clinical therapeutic responses to radiosurgery in individuals with cerebral arteriovenous malformation (AVM), we enrolled 18 patients years after they had received Gamma Knife radiosurgery for their cerebral AVM. The AVMs ...

journal_title：Journal of radiation research

authors： Guo WY,Pan HC,Wu HM,Hsieh WA,Tsai MH,Chow YM,Chung WY,Shiau CY,Chen SK,Chang WP

更新日期：2004-06-01 00:00:00

abstract：:The current study retrospectively analyzed the results of radiotherapy for clinically localized sebaceous carcinoma of the eyelid.We reviewed records of 83 patients with histologically confirmed sebaceous carcinoma who were treated radiotherapeutically between 1983 and 2015. Sixty-five patients (78%) were initially tr...

journal_title：Journal of radiation research

authors： Takagawa Y,Tamaki W,Suzuki S,Inaba K,Murakami N,Takahashi K,Igaki H,Nakayama Y,Shigematsu N,Itami J

更新日期：2019-10-23 00:00:00

abstract：:The aim of this study was to determine the outcomes and adverse events for 300 men with prostate cancer treated with 125iodine (125I) brachytherapy with and without external-beam radiation therapy (EBRT) at a single institution in Japan. Between February 2005 and November 2011, 300 consecutive patients with clinically...

journal_title：Journal of radiation research

authors： Maki S,Itoh Y,Kubota S,Okada T,Nakahara R,Ito J,Kawamura M,Naganawa S,Yoshino Y,Fujita T,Kato M,Gotoh M,Ikeda M

更新日期：2017-11-01 00:00:00

abstract：:Photon irradiation has been repeatedly suspected of increasing tumor cell motility and promoting locoregional recurrence of disease. This study was set up to analyse possible mechanisms underlying the potentially radiation-altered motility in medulloblastoma cells. Medulloblastoma cell lines D425 and Med8A were analyz...

journal_title：Journal of radiation research

authors： Rieken S,Rieber J,Brons S,Habermehl D,Rief H,Orschiedt L,Lindel K,Weber KJ,Debus J,Combs SE

更新日期：2015-05-01 00:00:00

abstract：:The present study was undertaken to determine relative biological effectiveness (RBE) values for simulated solar particle event (SPE) radiation on peripheral blood cells using Yucatan minipigs and electron-simulated SPE as the reference radiation. The results demonstrated a generally downward trend in the RBE values w...

journal_title：Journal of radiation research

authors： Sanzari JK,Wan SX,Diffenderfer ES,Cengel KA,Kennedy AR

更新日期：2014-03-01 00:00:00