Abstract:
:Herein we summarize the public health actions taken to mitigate exposure of the public to radiation after the Fukushima accident that occurred on 11 March 2011 in order to record valuable lessons learned for disaster preparedness. Evacuations from the radiation-affected areas and control of the distribution of various food products contributed to the reduction of external and internal radiation exposure resulting from the Fukushima incident. However, risk communication is also an important issue during the emergency response effort and subsequent phases of dealiing with a nuclear disaster. To assist with their healing process, sound, reliable scientific information should continue to be disseminated to the radiation-affected communities via two-way communication. We will describe the essential public health actions following a nuclear disaster for the early, intermediate and late phases that will be useful for radiological preparedness planning in response to other nuclear or radiological disasters.
journal_name
J Radiat Resjournal_title
Journal of radiation researchauthors
Shimura T,Yamaguchi I,Terada H,Robert Svendsen E,Kunugita Ndoi
10.1093/jrr/rrv013subject
Has Abstractpub_date
2015-05-01 00:00:00pages
422-9issue
3eissn
0449-3060issn
1349-9157pii
rrv013journal_volume
56pub_type
杂志文章,评审abstract::To clarify the nature of the genes that contribute to the radiosensitivity of human hematopoietic stem/progenitor cells (HSPCs), we analyzed the gene expression profiles detected in HSPCs irradiated with 2 Gy X-rays after culture with or without an optimal combination of hematopoietic cytokines. Highly purified CD34(+...
journal_title:Journal of radiation research
pub_type: 杂志文章
doi:10.1093/jrr/rrv071
更新日期:2016-01-01 00:00:00
abstract::We previously showed that free radicals and oxidative stress are involved in radiation-induced skin reactions. Since vitamin E (VE) is a particularly important lipophilic antioxidant, VE-deficient mice were used to examine its effects on radiation-induced skin damage. The VE content of the skin was reduced to one four...
journal_title:Journal of radiation research
pub_type: 杂志文章
doi:10.1269/jrr.10042
更新日期:2011-01-01 00:00:00
abstract::Hyper-radiosensitivity (HRS) is a well-known bioresponse under low-dose or low-dose-rate exposures. Although disorder of the DNA repair function, non-targeted effects and accumulation of cells in G2 have been experimentally observed, the mechanism for inducing HRS by long-term irradiation is still unclear. On the basi...
journal_title:Journal of radiation research
pub_type: 杂志文章
doi:10.1093/jrr/rrw110
更新日期:2017-05-01 00:00:00
abstract::To evaluate the feasibility of using radiosensitivity of peripheral leukocytes as a predictor of clinical therapeutic responses to radiosurgery in individuals with cerebral arteriovenous malformation (AVM), we enrolled 18 patients years after they had received Gamma Knife radiosurgery for their cerebral AVM. The AVMs ...
journal_title:Journal of radiation research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1269/jrr.45.269
更新日期:2004-06-01 00:00:00
abstract::The purpose of this study was to analyze the patterns of care and outcomes of patients with FIGO Stage I/II cervical cancer who underwent definitive radiotherapy (RT) at multiple Japanese institutions. The Japanese Radiation Oncology Study Group (JROSG) performed a questionnaire-based survey of their cervical cancer p...
journal_title:Journal of radiation research
pub_type: 杂志文章,多中心研究
doi:10.1093/jrr/rrv036
更新日期:2015-09-01 00:00:00
abstract::The aim of this research was to provide data from a single-center study of the treatment of synchronous hypopharyngeal cancer (HPC) and esophageal cancer (EC) with different treatment modalities. A total of 61 patients with synchronous HPC and EC were included in this study. Patients were treated with radiotherapy/che...
journal_title:Journal of radiation research
pub_type: 杂志文章
doi:10.1093/jrr/rrz042
更新日期:2019-10-23 00:00:00
abstract::The purpose of this review was to evaluate the impact of epidermal growth factor receptor (EGFR) mutation status on disease recurrence in patients treated with chemoradiotherapy (CRT) for locally advanced non-small cell lung cancer (NSCLC). A literature search was conducted and a total of three studies were analyzed. ...
journal_title:Journal of radiation research
pub_type: 杂志文章,评审
doi:10.1093/jrr/rrw075
更新日期:2016-09-01 00:00:00
abstract::A photoluminescence glass dosimeter, GD-301, was applied to the measurement of low absorbed doses in mice exposed to low-dose rate 137Cs gamma-rays. The dosimeter system consists of small rod-shaped glass chip detectors capable of embedded in the body of a mouse and an automatic readout device equipped with a standard...
journal_title:Journal of radiation research
pub_type: 杂志文章
doi:10.1269/jrr.41.129
更新日期:2000-06-01 00:00:00
abstract::The purpose of this study was to describe the results of definitive radiotherapy (RT) with concurrent chemotherapy for maxillary sinus carcinomas (MSCs) with neck lymph node metastasis to clarify its limitation. Local control (LC), progression-free survival (PFS) and overall survival (OS) rates were calculated using t...
journal_title:Journal of radiation research
pub_type: 杂志文章
doi:10.1093/jrr/rraa120
更新日期:2021-01-01 00:00:00
abstract::Reactive oxygen species continuously oxidize DNA bases and threaten the genetic integrity. Thymine glycol (TG), one of the representative oxidized products, is repaired mainly by base excision repair (BER). In Escherichia coli, endonuclease III (Nth) and endonuclease VIII (Nei) are known to actively remove TG from DNA...
journal_title:Journal of radiation research
pub_type: 杂志文章
doi:10.1269/jrr.07100
更新日期:2008-05-01 00:00:00
abstract::Whole brain irradiation (WBI) has become an indispensible tool in the treatment of head and neck cancer, and it has greatly improved patient survival rate and total survival time. In addition, prophylactic cranial irradiation (PCI) has dramatically decreased the incidence of brain metastatic carcinoma. However, WBI ma...
journal_title:Journal of radiation research
pub_type: 杂志文章
doi:10.1093/jrr/rrx041
更新日期:2017-11-01 00:00:00
abstract::Male C3H/HeN mice were exposed to 252Cf radiation and mated with unirradiated C57BL/6N females. F1 mice were analyzed for germline mutation at the paternally derived C3H/HeN allele of a hypervariable minisatellite locus, Ms6hm. This locus exhibited a high frequency of length change mutation spontaneously, and the muta...
journal_title:Journal of radiation research
pub_type: 杂志文章
doi:10.1269/jrr.37.217
更新日期:1996-09-01 00:00:00
abstract::Surgery is the standard modality for early-stage I-II non-small-cell lung cancer (NSCLC). Generally, patients who are >80 years old tend to have more comorbidities and inferior physical status than younger patients. Stereotactic body radiation therapy (SBRT) may provide an alternative treatment for this group of patie...
journal_title:Journal of radiation research
pub_type: 杂志文章
doi:10.1093/jrr/rraa027
更新日期:2020-07-06 00:00:00
abstract::Chromatin-regulating proteins represent a large class of novel targets for cancer therapy. In the context of radiotherapy, acetylation and deacetylation of histones by histone acetyltransferases (HATs) and histone deacetylases (HDACs) play important roles in the repair of DNA double-strand breaks generated by ionizing...
journal_title:Journal of radiation research
pub_type: 杂志文章,评审
doi:10.1093/jrr/rrt227
更新日期:2014-07-01 00:00:00
abstract::The aim of the study was to compare clinical outcomes and toxicity between 3D conformal radiotherapy (3DCRT) and image-guided intensity-modulated radiotherapy (IG-IMRT) administered through helical tomotherapy in locally advanced rectal cancer (LARC) patients receiving preoperative chemoradiotherapy. We reviewed 144 p...
journal_title:Journal of radiation research
pub_type: 杂志文章
doi:10.1093/jrr/rrw098
更新日期:2017-03-01 00:00:00
abstract::The 239Pu distribution in the 12.5-day-old rat conceptus was compared between in vivo and in vitro experimental systems to establish a possible mechanism of cross-placental transfer of this radionuclide. In the in vivo study, plutonium citrate solution was injected intravenously to pregnant Wistar rats. In the in vitr...
journal_title:Journal of radiation research
pub_type: 杂志文章
doi:10.1269/jrr.33.301
更新日期:1992-12-01 00:00:00
abstract::We analyzed the correlation between primary tumor response within 6 months after radiation therapy (RT) including proton beam therapy (PBT) and progression free survival rate (PFS) in patients with nasal cavity and paranasal sinus malignancies to clarify the impact of early radiological evaluation of treatment respons...
journal_title:Journal of radiation research
pub_type: 杂志文章
doi:10.1093/jrr/rrs021
更新日期:2012-09-01 00:00:00
abstract::Photon irradiation has been repeatedly suspected of increasing tumor cell motility and promoting locoregional recurrence of disease. This study was set up to analyse possible mechanisms underlying the potentially radiation-altered motility in medulloblastoma cells. Medulloblastoma cell lines D425 and Med8A were analyz...
journal_title:Journal of radiation research
pub_type: 杂志文章
doi:10.1093/jrr/rru120
更新日期:2015-05-01 00:00:00
abstract::The aim of this study was to evaluate the effectiveness and tolerability of definitive chemo-radiation or radiotherapy alone in patients with esophageal cancer. We retrospectively analyzed the medical records of n = 238 patients with squamous cell carcinoma or adenocarcinoma of the esophagus treated with definitive ra...
journal_title:Journal of radiation research
pub_type: 杂志文章
doi:10.1093/jrr/rrv022
更新日期:2015-07-01 00:00:00
abstract::We aimed to investigate the effect of chronic radiation exposure associated with the Fukushima Daiichi Nuclear Power Plant (FNPP) accident on the testes of boar and inobuta (a hybrid of Sus scrofa and Sus scrofa domestica). This study examined the contamination levels of radioactive caesium (Cs), especially (134)Cs an...
journal_title:Journal of radiation research
pub_type: 杂志文章
doi:10.1093/jrr/rrv070
更新日期:2015-12-01 00:00:00
abstract::To evaluate the present levels of 239,240Pu and U in residents living near the Semipalatinsk nuclear test site, more than 70 bone samples were obtained at autopsy. The subjects ranged in age from 30 to 86 years (mean 59.3+/-12.9). Most of the samples consisted of victims who died of various diseases. Plutonium and U w...
journal_title:Journal of radiation research
pub_type: 杂志文章
doi:10.1269/jrr.47.a85
更新日期:2006-02-01 00:00:00
abstract::The prognosis and treatment of thyroid cancer depends on the type and stage of the disease. Radiosensitivity differs among cancer cells owing to their varying capacity for repair after irradiation. Radioactive iodine can be used to destroy thyroid cancer cells. However, patient prognosis and improvement after irradiat...
journal_title:Journal of radiation research
pub_type: 杂志文章
doi:10.1093/jrr/rry097
更新日期:2019-03-01 00:00:00
abstract::Exposure to ionizing radiation leads to severe damages in radiosensitive organs and induces acute radiation syndrome, including effects on the hematopoietic system and gastrointestinal system. In this study, the radioprotective ability of KMRC011, a novel toll-like receptor 5 (TLR5) agonist, was investigated in C57BL6...
journal_title:Journal of radiation research
pub_type: 杂志文章
doi:10.1093/jrr/rrz024
更新日期:2019-07-01 00:00:00
abstract::The present paper reports and discusses the results concerning both the inter- and intrafraction accuracy achievable combining the immobilization system employed in patients with head-and-neck, brain and skull base tumors with image guidance at our particle therapy center. Moreover, we investigated the influence of in...
journal_title:Journal of radiation research
pub_type: 杂志文章
doi:10.1093/jrr/rrt038
更新日期:2013-07-01 00:00:00
abstract::Ionizing radiation induces biological effects not only in irradiated cells but also in non-irradiated cells, which is called the bystander effect. Recently, in vivo and in vitro experiments have suggested that both gap junction hemichannel connexin43 (Cx43) and extracellular adenosine triphosphate (ATP) released from ...
journal_title:Journal of radiation research
pub_type: 杂志文章
doi:10.1093/jrr/rrs014
更新日期:2012-07-01 00:00:00
abstract::Disufiram (a drug used for the treatment of alcoholism) protected microsomal membranes and plasmid DNA against damages induced by gamma-radiation. The peroxidation of membrane lipids increased linearly with the radiation dose up to 600 Gy, and the presence of disulfiram inhibited membrane lipid peroxidation as assayed...
journal_title:Journal of radiation research
pub_type: 杂志文章
doi:10.1269/jrr.44.255
更新日期:2003-09-01 00:00:00
abstract::Neutron dose is transferred to biological materials through the recoil protons produced by elastic scattering. When a low-velocity proton collides with the atoms or molecules of a target, it changes to a hydrogen atom by electron capture; this hydrogen atom then changes to a proton by losing the electron. Because the ...
journal_title:Journal of radiation research
pub_type: 杂志文章
doi:10.1269/jrr.45.351
更新日期:2004-09-01 00:00:00
abstract::Numerous attempts have been made to estimate the distance at which 50% of the individuals exposed to the A-bombing of Hiroshima and Nagasaki died, ostensibly from their exposure to ionizing radiation. It is difficult to convert most of these distance estimates to a dose-related LD50, since radiation shielding was igno...
journal_title:Journal of radiation research
pub_type: 杂志文章,评审
doi:10.1269/jrr.32.supplement_154
更新日期:1991-03-01 00:00:00
abstract::The purpose of this study was to analyze the clinical outcomes of simultaneous modulated accelerated radiotherapy (SMART) in patients with nasopharyngeal carcinoma (NPC). A total of 97 patients who underwent SMART for NPC between August 2005 and November 2011 were evaluated. The prescribed dose was 69.9 Gy/30 fraction...
journal_title:Journal of radiation research
pub_type: 杂志文章
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更新日期:2014-07-01 00:00:00
abstract::The expression of oncogenes was studied in 12 types of 178 mouse tumors induced by radiations and chemicals. DNA was analyzed in tumors in which the overexpression of oncogenes was noted. Amplification of the myc oncogene was found in chemically induced sarcomas, but not in sarcomas induced by radiation. Activation of...
journal_title:Journal of radiation research
pub_type: 杂志文章
doi:10.1269/jrr.32.supplement2_235
更新日期:1991-12-01 00:00:00