[In vivo metabolism of rat submaxillary gland phospholipids].

Abstract:

:The metabolism of the phospholipids of the submaxillary gland are studied after intraperitoneal injections of [32P]-orthophosphate in several groups of rats. The gland contains mainly phosphatidylcholines and phosphatidylethanolamines and in smaller quantities phosphatidylinositols, phosphatidylserines, sphingomyelins, polyglycerophosphatides, lysophosphatidylcholines and phosphatidic acids. The specific activities of the phospholipids measured in relation to the time (1/2 hour, 1, 2 and 3 hours) show a strong incorporation in the phosphatidylinositols then in the phosphatidylcholines. The other phospholipids have lower activities. The specific activities of the phospholipids measured one hour after injection of different pharmacodynamic agents show the phosphatidylinositols, phosphatidylcholines, sphingomyelins and lysophosphatidylcholines are altered. Acetylcholine increases their turnover, Atropine reduces it, and the addition of atropine counteracts the effect of acetylcholine in all these phospholipids.

journal_name

Biochimie

journal_title

Biochimie

authors

Leclercq C,Di Costanzo G

doi

10.1016/s0300-9084(76)80443-9

keywords:

subject

Has Abstract

pub_date

1976-01-01 00:00:00

pages

359-65

issue

3

eissn

0300-9084

issn

1638-6183

pii

S0300-9084(76)80443-9

journal_volume

58

pub_type

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