Abstract:
:The metabolism of the phospholipids of the submaxillary gland are studied after intraperitoneal injections of [32P]-orthophosphate in several groups of rats. The gland contains mainly phosphatidylcholines and phosphatidylethanolamines and in smaller quantities phosphatidylinositols, phosphatidylserines, sphingomyelins, polyglycerophosphatides, lysophosphatidylcholines and phosphatidic acids. The specific activities of the phospholipids measured in relation to the time (1/2 hour, 1, 2 and 3 hours) show a strong incorporation in the phosphatidylinositols then in the phosphatidylcholines. The other phospholipids have lower activities. The specific activities of the phospholipids measured one hour after injection of different pharmacodynamic agents show the phosphatidylinositols, phosphatidylcholines, sphingomyelins and lysophosphatidylcholines are altered. Acetylcholine increases their turnover, Atropine reduces it, and the addition of atropine counteracts the effect of acetylcholine in all these phospholipids.
journal_name
Biochimiejournal_title
Biochimieauthors
Leclercq C,Di Costanzo Gdoi
10.1016/s0300-9084(76)80443-9keywords:
subject
Has Abstractpub_date
1976-01-01 00:00:00pages
359-65issue
3eissn
0300-9084issn
1638-6183pii
S0300-9084(76)80443-9journal_volume
58pub_type
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