Analyzing data in which the outcome is time to an event part II: The presence of multiple covariates.

abstract：:Moderately low-protein diets lead to a rapid increase in food intake and body fat. The increase in feeding is associated with a decrease in the concentration of serum urea nitrogen, suggesting that the low-protein-induced increase in food intake may be related to the decreased metabolism of nitrogen from amino acids. ...

journal_title：Nutritional neuroscience

authors： White BD,Du F,Higginbotham DA

更新日期：2003-12-01 00:00:00

abstract：:Objective: Amylin acts on the lateral dorsal tegmental nucleus (LDT), resulting in anorexic and weight-loss effects and activates thermogenesis in the interscapular brown adipose tissue (IBAT). In addition, it induces neuronal nitric oxide synthase (nNOS) and choline acetyltransferase (ChAT)-mediated feeding. However,...

journal_title：Nutritional neuroscience

authors： Fan K,Li Q,Pan D,Liu H,Li P,Hai R,Du C

更新日期：2020-04-25 00:00:00

abstract：:Apelin, the endogenous peptide ligand of the APJ receptor, is expressed in brain regions implicated in food and water intake. This study reports for the first time, the effect of apelin-12, one of the most potent apelin peptides, on spontaneous (nocturnal) feeding. Randomised intracerebroventricular injection of 1, 3 ...

journal_title：Nutritional neuroscience

authors： O'Shea M,Hansen MJ,Tatemoto K,Morris MJ

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVES:Stress in known to alter hormonal systems. Pharmacological doses of tryptophan, the essential amino acid precursor of serotonin, increase circulating leptin and decrease ghrelin in normal healthy adults. Because systemically injected leptin inhibits stress-induced behavioral deficits and systemically injecte...

journal_title：Nutritional neuroscience

authors： Gul S,Saleem D,Haleem MA,Haleem DJ

更新日期：2019-06-01 00:00:00

abstract：:This symposium examined current trends in neuroscience and developmental psychology as they apply to assessing the effects of nutrients on brain and behavioral development of 0-6-year-olds. Although the spectrum of nutrients with brain effects has not changed much in the last 25 years, there has been an explosion in n...

journal_title：Nutritional neuroscience

authors： Rosales FJ,Zeisel SH

更新日期：2008-06-01 00:00:00

abstract：:Introduction: Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders characterized by abnormal development of cognitive, social, and communicative skills. Although ASD aetiology and pathophysiology are still unclear, various nutritional factors have been investigated as potential risk factors for AS...

journal_title：Nutritional neuroscience

authors： Infante M,Sears B,Rizzo AM,Mariani Cerati D,Caprio M,Ricordi C,Fabbri A

更新日期：2020-10-01 00:00:00

abstract：:The effects of perinatal undernutrition on the number of neurons and apoptotic cells of the locus coeruleus (LC) of female and male rats at postpartum days 7, 12, 20, 30 and 60 were studied. Undernutrition reduces the number of neurons in both sexes without affecting cell death, as indicated by the ratio of apoptotic ...

journal_title：Nutritional neuroscience

authors： Pinos H,Collado P,Salas M,Pérez-Torrero E

更新日期：2006-10-01 00:00:00

abstract：:Introduction: Oxidative stress is known to contribute to the pathogenesis of neurodegenerative disorders. An ethanolic turmeric (Curcuma longa L.) extract containing curcumin has been reported to produce antioxidant effects. Objective: The present study aims to investigate the possible neuroprotective effects of the e...

journal_title：Nutritional neuroscience

authors： Yuliani S,Mustofa,Partadiredja G

更新日期：2019-11-01 00:00:00

abstract：:Mitochondrial decay due to oxidative damage is a contributor to brain aging and age-related neurodegenerative diseases, such as Alzheimer's disease (AD) and Parkinson's disease (PD). One type of mitochondrial decay is oxidative modification of key mitochondrial enzymes. Enzyme dysfunction, that is due to poor binding ...

journal_title：Nutritional neuroscience

authors： Liu J,Ames BN

更新日期：2005-04-01 00:00:00

abstract：OBJECTIVES:Western-style diets high in saturated fat and refined carbohydrate have been shown to alter gut microbiota as well as being associated with altered behaviour and learning ability. The objective of this study was to determine the effects of short-term intake of a Western-style diet on intestinal cytokine expr...

journal_title：Nutritional neuroscience

authors： Ohland CL,Pankiv E,Baker G,Madsen KL

更新日期：2016-10-01 00:00:00

abstract：:Dietary sulfur amino acid content is a major determinant of glutathione concentration in some tissues. We examined whether brain glutathione (GSH), a key component of antioxidant defense important for minimizing ischemic injury, was also responsive to short-term sulfur amino acid deficiency. Female Long-Evans adult ra...

journal_title：Nutritional neuroscience

authors： Paterson PG,Lyon AW,Kamencic H,Andersen LB,Juurlink BH

更新日期：2001-01-01 00:00:00

abstract：PURPOSE:The Mediterranean diet has been postulated as a protective factor against different diseases including stroke. Thus, an epidemiological study in a Mediterranean country, such as Spain, focused on diet may offer new insights of the potential benefits of this nutritional pattern to prevent the onset of cerebrovas...

journal_title：Nutritional neuroscience

authors： Martínez-González MA,Sanchez-Villegas A,De Irala J,Marti A,Martínez JA

更新日期：2002-02-01 00:00:00

abstract：:Background: Alzheimer's disease is known as one of the fastest growing lethal diseases worldwide where we have limited and undesired ways for regulating its pathological progress. Now-a-days, nutritional compounds have been using to treat several brain disorders and one of them; vitamins were strongly reported to comb...

journal_title：Nutritional neuroscience

authors： Alam J

更新日期：2020-10-01 00:00:00

abstract：:Given that protein malnutrition induces structural, neurochemical and functional changes in the CNS, the present study aimed to investigate the effects of different early periods of protein malnutrition on the behavior and reactivity to diazepam (DZ) in a model of anxiety: the fear-potentiated startle (FPS). Male Wist...

journal_title：Nutritional neuroscience

authors： Françolin-Silva AL,Brandão ML,Almeida SS

更新日期：2007-02-01 00:00:00

abstract：:Objectives: Unfavorable lactation influences brain excitability and behavioral reactions in adults. Administration early in life of the cholinergic agonist, pilocarpine, even at non-convulsive doses, alters the brain excitability-related phenomenon known as cortical spreading depression (CSD), and produce anxiogenic-l...

journal_title：Nutritional neuroscience

authors： Benevides RDL,de-Lima SMV,Chagas CL,de Lima CF,Abadie-Guedes R,Guedes RCA

更新日期：2020-09-11 00:00:00

abstract：OBJECTIVES:It has been shown that calcitriol and all-trans retinoic acid (ATRA) have modulatory effects on the immune system. The present study investigates the synergistic effects of combination treatment of calcitriol and ATRA in experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (...

journal_title：Nutritional neuroscience

authors： Parastouei K,Mirshafiey A,Eshraghian MR,Shiri-Shahsavar MR,Solaymani-Mohammadi F,Chahardoli R,Alvandi E,Saboor-Yaraghi AA

更新日期：2018-04-01 00:00:00

abstract：:Organophosphorus compounds are widely used in agriculture. Epidemiological studies propose that pesticide exposure is a risk factor for Alzheimer's disease (AD), but the mechanisms are unclear. Here, we investigated the impact of malathion exposure on the cognitive ability and the underlying mechanisms in rats. Moreov...

journal_title：Nutritional neuroscience

authors： Mohammadzadeh L,Abnous K,Razavi BM,Hosseinzadeh H

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVES:Undernutrition during development alters the expression of peptides that control energy expenditure and feeding behavior. Estrogens can also modulate these peptides. Here, we analyze whether the early postnatal administration of estradiol modulates the effects of undernutrition on neuroendocrine parameters i...

journal_title：Nutritional neuroscience

authors： Carrillo B,Collado P,Díaz F,Chowen JA,Pinos H

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:Our aim was to investigate the effects of Spirulina on BV-2 microglial cell cytotoxicity and inflammatory genes expression. METHODS:BV-2 microglial cells were treated with lipopolysaccharide (LPS) (1 µg/ml) and various concentrations of Spirulina platensis water extract or its active component (C-phycocyanin...

journal_title：Nutritional neuroscience

authors： Chen JC,Liu KS,Yang TJ,Hwang JH,Chan YC,Lee IT

更新日期：2012-11-01 00:00:00

abstract：:The effects of iodine deficiency on growth and development are known as the iodine deficiency disorders (IDDs). Most common is goitre at all ages, but most significant are the effects on brain development during pregnancy. The major effect of iodine deficiency is the clinical syndrome of endemic cretinism characterise...

journal_title：Nutritional neuroscience

authors： Hetzel BS

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the nutritional status of children with SMA types II and III in a Chinese population. METHODS:We performed a retrospective medical record review of prospectively collected data from children with SMA types II and III in a single centre. We analysed data including clinical parameters, anthropometr...

journal_title：Nutritional neuroscience

authors： Zhou Y,Chen J,Gong X,Lu Z,Hua H,Zhu X,Shi P,Li X,Zhou S,Wang Y,Qian T

更新日期：2021-01-23 00:00:00

abstract：:Food intake decreases and a conditioned taste aversion is induced when rats are fed a diet that is devoid of an indispensable amino acid. The purpose of this study was to characterize the meal patterns associated with (1) the onset of anorexia after the initial recognition of a threonine deficiency and (2) after the d...

journal_title：Nutritional neuroscience

authors： Feurté S,Tomé D,Gietzen DW,Even PC,Nicolaïdis S,Fromentin G

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVE:The aim of the present study is to investigate the effects of topiramate on the fat mass/obesity-associated protein (FTO) and on the neuropeptide Y (NPY) level in the hypothalamus depending on the recently increased prevalence of obesity. METHOD:In this study, twenty-four female rats were divided into four e...

journal_title：Nutritional neuroscience

authors： Alkan I,Altunkaynak BZ,Altun G,Erener E

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to assess the association between cerebral infarction (CI), nutritional status, and depression. METHODS:Subjects with and without CI (n = 146; 73 CI vs. 73 non-CI) were recruited from Kyung Hee University Medical Center (Seoul, Korea) and were matched according to age and gende...

journal_title：Nutritional neuroscience

authors： Lim HJ,Choue R

更新日期：2012-01-01 00:00:00

abstract：:Endogenous neuropeptide Y (NPY) levels increase during fasting and before dark onset in rats. The feeding that follows these states elicits the release of serotonin in the lateral hypothalamus (LH), as part of the physiological mechanisms controlling satiety. With the hypothesis that exogenous NPY-induced feeding shou...

journal_title：Nutritional neuroscience

authors： Mori RC,Telles MM,Guimarães RB,Novo NF,Juliano Y,Nascimento CM,Ribeiro EB

更新日期：2004-08-01 00:00:00

abstract：OBJECTIVES:To explore the association between dietary factors including fat, fruit and vegetable intake, dairy and meat consumption, and health-related quality of life (HRQOL), disability and relapse rate in a large international sample of people with multiple sclerosis (MS). METHODS:Participants with MS were recruite...

journal_title：Nutritional neuroscience

authors： Hadgkiss EJ,Jelinek GA,Weiland TJ,Pereira NG,Marck CH,van der Meer DM

更新日期：2015-04-01 00:00:00

abstract：:Theanine, γ-glutamylethylamide, is one of the major amino acid components in green tea. On the basis of the preventive effect of theanine intake after weaning on stress-induced impairment of recognition memory, the advantageous effect of theanine intake on recognition memory was examined in young rats, which were fed ...

journal_title：Nutritional neuroscience

authors： Tamano H,Fukura K,Suzuki M,Sakamoto K,Yokogoshi H,Takeda A

更新日期：2014-11-01 00:00:00

abstract：:Objective: We evaluate whether the consumption of fructose for 8 weeks affects enzymes and transcription factors of the lipogenic and inflammatory pathways in the hypothalamus of Wistar rats. Methods: At 30 days, the animals were divided into groups: Control (C) and Fructose (F) and maintained with free access to feed...

journal_title：Nutritional neuroscience

authors： Batista LO,Ramos VW,Rosas Fernández MA,Concha Vilca CM,Albuquerque KT

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:To evaluate cognitive functions and behavioral changes in the patients with vitamin B12 deficiency neurological syndromes (VBDNS) using detailed clinical psychometric and P3 studies and their response to treatment. METHODS:The patients with VBDNS were included and their detailed medical history was recorded...

journal_title：Nutritional neuroscience

authors： Kalita J,Agarwal R,Chandra S,Misra UK

更新日期：2013-01-01 00:00:00

abstract：:The effects of noise-induced arousal on chewing, subjective motivation to eat, the pleasantness of sweet food, and food intake were investigated. Twenty-four healthy normal weight male subjects received cookies differing in sucrose content (2%, 11%, 18% or 27%) before, during, and after 10 min of intermittent white no...

journal_title：Nutritional neuroscience

authors： Macht M

更新日期：1998-01-01 00:00:00