The investigation of the effects of topiramate on the hypothalamic levels of fat mass/obesity-associated protein and neuropeptide Y in obese female rats.

abstract：:Objectives: Glucocorticoid receptor (GR) expressed in hippocampus is critical for the homeostasis of stress responses and susceptible to epigenetic modulation caused by maternal factors. Here we show that maternal methyl nutrition causes sex-biased changes in hippocampal expression of GR exon 1 mRNA variants, associat...

journal_title：Nutritional neuroscience

authors： Yang Y,Yang S,Jia Y,Yin C,Zhao R

更新日期：2020-08-25 00:00:00

abstract：OBJECTIVES:The green seaweed Ulva sp. contains a large amount of ulvans, a family of sulphated polysaccharides. The present study was designed to investigate in rats the antidepressant- and anxiolytic-like effects of a hydrophilic extract of Ulva sp. (MSP) containing about 45% of ulvans. METHODS:After a 14-day adminis...

journal_title：Nutritional neuroscience

authors： Violle N,Rozan P,Demais H,Nyvall Collen P,Bisson JF

更新日期：2018-05-01 00:00:00

abstract：:Introduction: Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders characterized by abnormal development of cognitive, social, and communicative skills. Although ASD aetiology and pathophysiology are still unclear, various nutritional factors have been investigated as potential risk factors for AS...

journal_title：Nutritional neuroscience

authors： Infante M,Sears B,Rizzo AM,Mariani Cerati D,Caprio M,Ricordi C,Fabbri A

更新日期：2020-10-01 00:00:00

abstract：:Background: The aetiology of Attention Deficit Hyperactivity Disorder (ADHD) continues to be debated, although several contributing factors have been acknowledged. Objective: Assess the association between weight, birth attributes, exercise and sleep habits, dietary intake and adherence to a Mediterranean diet, and im...

journal_title：Nutritional neuroscience

authors： San Mauro Martin I,Sanz Rojo S,Garicano Vilar E,González Cosano L,Conty de la Campa R,Blumenfeld Olivares JA

更新日期：2019-09-03 00:00:00

abstract：:Background: The two metabolites of vitamin D; serum 25-hydroxyvitamin D3 (25(OH)D3) and D2 (25(OH)D2), and their independent roles in mood regulation are unexplored. This study aims to examine 25(OH)D3 and 25(OH)D2 and their interplay with depression symptoms. Materials and Methods: Utilizing data from the U.S. Nation...

journal_title：Nutritional neuroscience

authors： Bigman G

更新日期：2020-07-20 00:00:00

abstract：:A high-fat diet (HFD) during pregnancy influences the neurodevelopment of progeny, particularly in the hippocampus, a brain region involved in cognitive processes. The hippocampus has high levels of leptin receptors (Ob-R) that participate in synaptic plasticity. This study examined the effect of maternal HFD during g...

journal_title：Nutritional neuroscience

authors： Cortés-Álvarez NY,Vuelvas-Olmos CR,Pinto-González MF,Guzmán-Muñiz J,Gonzalez-Perez O,Moy-López NA

更新日期：2020-02-19 00:00:00

abstract：:Organophosphorus compounds are widely used in agriculture. Epidemiological studies propose that pesticide exposure is a risk factor for Alzheimer's disease (AD), but the mechanisms are unclear. Here, we investigated the impact of malathion exposure on the cognitive ability and the underlying mechanisms in rats. Moreov...

journal_title：Nutritional neuroscience

authors： Mohammadzadeh L,Abnous K,Razavi BM,Hosseinzadeh H

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to determine effects of probiotic yogurt and multispecies probiotic capsule supplementation on mental health and hypothalamic-pituitary-adrenal axis in petrochemical workers. METHODS:The present randomized double-blind, placebo-controlled trial was conducted on 70 petrochemical work...

journal_title：Nutritional neuroscience

authors： Mohammadi AA,Jazayeri S,Khosravi-Darani K,Solati Z,Mohammadpour N,Asemi Z,Adab Z,Djalali M,Tehrani-Doost M,Hosseini M,Eghtesadi S

更新日期：2016-11-01 00:00:00

abstract：:This study aimed to investigate the effect of a single injection of pilocarpine upon the phenomenon of cortical spreading depression (SD), in adult rats submitted to early malnutrition and/or to REM-sleep deprivation for 72h prior to the SD-recordings. The SD was recorded continuously for 3-4h in 13 well-nourished (W)...

journal_title：Nutritional neuroscience

authors： De Vasconcelos CA,De Oliveira JA,De Oliveira Costat LA,Guedes RC

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVES:Western-style diets high in saturated fat and refined carbohydrate have been shown to alter gut microbiota as well as being associated with altered behaviour and learning ability. The objective of this study was to determine the effects of short-term intake of a Western-style diet on intestinal cytokine expr...

journal_title：Nutritional neuroscience

authors： Ohland CL,Pankiv E,Baker G,Madsen KL

更新日期：2016-10-01 00:00:00

abstract：:The kynurenine (KYN) pathway of tryptophan metabolism produces several neuroactive metabolites, including 3-hydroxykynurenine (3HK). The pathway is subject to regulation by a number of effectors including pregnancy and availability of vitamin B-6. Vitamin B-6 depleted humans and animals excrete abnormally high concent...

journal_title：Nutritional neuroscience

authors： van de Kamp JL,Smolen A

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVES:Genistein is a plant-derived estrogenic isoflavone commonly found in dietary and therapeutic supplements, due to its potential health benefits. Growth hormone-releasing hormone (GHRH) and somatostatin (SS) are neurosecretory peptides synthesized in neurons of the hypothalamus and regulate the growth hormone ...

journal_title：Nutritional neuroscience

authors： Trifunović S,Manojlović-Stojanoski M,Ristić N,Nestorović N,Medigović I,Živanović J,Milošević V

更新日期：2016-12-01 00:00:00

abstract：:Given that protein malnutrition induces structural, neurochemical and functional changes in the CNS, the present study aimed to investigate the effects of different early periods of protein malnutrition on the behavior and reactivity to diazepam (DZ) in a model of anxiety: the fear-potentiated startle (FPS). Male Wist...

journal_title：Nutritional neuroscience

authors： Françolin-Silva AL,Brandão ML,Almeida SS

更新日期：2007-02-01 00:00:00

abstract：:A debate is open in the literature concerning the safety of low (dietary) versus high (intoxicating or addicting) alcohol consumption. Epidemiological data do indeed suggest that moderate ethanol intake may have beneficial effects, at least at cardiovascular level. On the other hand there are few data on the effect of...

journal_title：Nutritional neuroscience

authors： Battaini F,Pascale A,Ancona DM,Cagiano R,Cuomo V,Govoni S

更新日期：1998-01-01 00:00:00

abstract：:Objectives: Apigenin is the most common bioflavonoid known to be biologically active after systemic administration and show multiple pharmacological effects. The present study was designed to explore the role of apigenin in pentylenetetrazole (PTZ) kindling associated cognitive and behavioural impairments in the mouse...

journal_title：Nutritional neuroscience

authors： Sharma P,Sharma S,Singh D

更新日期：2020-02-01 00:00:00

abstract：:Mitochondrial decay due to oxidative damage is a contributor to brain aging and age-related neurodegenerative diseases, such as Alzheimer's disease (AD) and Parkinson's disease (PD). One type of mitochondrial decay is oxidative modification of key mitochondrial enzymes. Enzyme dysfunction, that is due to poor binding ...

journal_title：Nutritional neuroscience

authors： Liu J,Ames BN

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:The rates of co-morbid depression with elderly diabetes are reportedly high. Although the intake of several nutrients has been suggested to be associated with depressive symptoms, the chronic effects of carbohydrate intake on mood remain unclear. In the current study, the association of the carbohydrate ener...

journal_title：Nutritional neuroscience

authors： Umegaki H,Iimuro S,Araki A,Sakurai T,Iguchi A,Yoshimura Y,Ohashi Y,Ito H

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVES:To investigate the effects of Calpis sour milk whey, a Lactobacillus helveticus-fermented milk product, on learning and memory. METHODS:We evaluated improvement in scopolamine-induced memory impairment using the spontaneous alternation behaviour test, a measure of short-term memory. We also evaluated learni...

journal_title：Nutritional neuroscience

authors： Ohsawa K,Uchida N,Ohki K,Nakamura Y,Yokogoshi H

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVE:The consumption of hyperlipidic diets has grown markedly in recent decades, and several studies have linked this consumption with the development of neurodegenerative diseases. Conversely, hyperlipidic diets have been used as an alternative therapy for refractory epilepsy. The purpose of this study was to eva...

journal_title：Nutritional neuroscience

authors： Pessoa D,Cruz R,Machado B,Tenorio B,Nogueira R

更新日期：2016-06-01 00:00:00

abstract：:Background: Essential fatty acids (EFAs) and non-essential fatty acids (nEFAs) exert experimental and clinical neuroprotection in neurodegenerative diseases. The main EFAs, eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), nEFAs, and oleic acid (OA) contained in olive and fish oils are inserted into the cell me...

journal_title：Nutritional neuroscience

authors： Morales-Martínez A,Zamorano-Carrillo A,Montes S,El-Hafidi M,Sánchez-Mendoza A,Soria-Castro E,Martínez-Lazcano JC,Martínez-Gopar PE,Ríos C,Pérez-Severiano F

更新日期：2021-01-01 00:00:00

abstract：:The uncertainty of the role of serum cholesterol in neurodevelopment of children has largely hampered the implementation of the fat recommendation to children in the general population. We explored whether serum cholesterol concentrations are associated with cognitive achievements, academic performance in school-aged ...

journal_title：Nutritional neuroscience

authors： Perry LA,Stigger CB,Ainsworth BE,Zhang J

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:This study was designed to review the effect of chronic aluminium exposure on interleukin-6 (IL-6) secretion in the posterior brain and test the putative modulating effect of fenugreek seeds. METHODS:Female Wistar rats were divided into four groups: control; AlCl3 during 5 months (500 mg/kg body weight, intr...

journal_title：Nutritional neuroscience

authors： Belaïd-Nouira Y,Bakhta H,Samoud S,Trimech M,Haouas Z,Ben Cheikh H

更新日期：2013-09-01 00:00:00

abstract：:Objective: The association between vitamin E supplementation and Alzheimer's disease (AD) was controversial because of conflicting data in the literature. This study was designed to systematically evaluate evidence about the efficacy of vitamin E supplementation not only on the risk but also on the progression of AD. ...

journal_title：Nutritional neuroscience

authors： Wang W,Li J,Zhang H,Wang X,Zhang X

更新日期：2021-01-01 00:00:00

abstract：:Studies using traditional treatment strategies for mild traumatic brain injury (TBI) have produced limited clinical success. Interest in treatment for mild TBI is at an all time high due to its association with the development of chronic traumatic encephalopathy and other neurodegenerative diseases, yet therapeutic op...

journal_title：Nutritional neuroscience

authors： Lucke-Wold BP,Logsdon AF,Nguyen L,Eltanahay A,Turner RC,Bonasso P,Knotts C,Moeck A,Maroon JC,Bailes JE,Rosen CL

更新日期：2018-02-01 00:00:00

abstract：:We compared the maturation of the monosynaptic stretch reflex in control rats and in rats submitted to neonatal malnutrition. Electrical stimulations of the sciatic nerve were applied in wakeful rats of different ages (21-90 days) to record, by surface electrodes, the maximal direct motor response (M(max)) or the maxi...

journal_title：Nutritional neuroscience

authors： Freitas-Silva SR,Manhães-de-Castro R,Pérot C

更新日期：2008-10-01 00:00:00

abstract：:Objective: Alzheimer's disease (AD), a neurodegenerative disorder, involves brain insulin signaling cascades and insulin resistance (IR). Because of limited treatment options, new treatment strategies are mandatory. Green coffee bean extract (GCBE) was reported to attenuate IR and improve brain energy metabolism. We a...

journal_title：Nutritional neuroscience

authors： Mohamed HE,Asker ME,Younis NN,Shaheen MA,Eissa RG

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:Major depressive disorder is a debilitating and recurrent psychiatric disorder. Blueberries have several biological properties, including neuroprotective effects, through antioxidant and anti-inflammatory actions. The aim of this study was to evaluate the effect of blueberry extract on depressive-like behavio...

journal_title：Nutritional neuroscience

authors： Spohr L,Luduvico KP,Soares MSP,Bona NP,Oliveira PS,de Mello JE,Alvez FL,Teixeira FC,Felix AOC,Stefanello FM,Spanevello RM

更新日期：2020-09-21 00:00:00

abstract：OBJECTIVE:The purpose of this study was to assess the association between cerebral infarction (CI), nutritional status, and depression. METHODS:Subjects with and without CI (n = 146; 73 CI vs. 73 non-CI) were recruited from Kyung Hee University Medical Center (Seoul, Korea) and were matched according to age and gende...

journal_title：Nutritional neuroscience

authors： Lim HJ,Choue R

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVES:Stress in known to alter hormonal systems. Pharmacological doses of tryptophan, the essential amino acid precursor of serotonin, increase circulating leptin and decrease ghrelin in normal healthy adults. Because systemically injected leptin inhibits stress-induced behavioral deficits and systemically injecte...

journal_title：Nutritional neuroscience

authors： Gul S,Saleem D,Haleem MA,Haleem DJ

更新日期：2019-06-01 00:00:00

abstract：:Newborn rats maintain mother-litter bonds by using olfactory signals. At birth, units in the olfactory glomeruli (OG) are immature and vulnerable to noxious epigenetic factors like undernutrition. Because little is known about the effects of neonatal undernutrition upon the OG morphological organization, different OG ...

journal_title：Nutritional neuroscience

authors： Frias C,Torrero C,Regalado M,Salas M

更新日期：2006-02-01 00:00:00