Prolonged hyperinsulinemic hypoglycemia in a small for date preterm.

Abstract:

:Hyperinsulinism is an important cause of hypoglycemia in early infancy. Many forms of hyperinsulinemic hypoglycemia are described: transient, prolonged, persistent. Transient forms are well recognized in infants of diabetic mother; prolonged forms are responsible for the hypoglycemia in small-for-date (SGA) infants and asphyxiated newborns. Persistent hyperinsulinemic hypoglycemia occurs in a group of congenital disorders associated with an abnormality of beta-cell regulation throughout the pancreas. Accurate diagnosis and treatment are essential in all various forms of hyperinsulinism also because newborns are at high risk of permanent brain damage. We report a case of prolonged hyperinsulinemic hypoglycemia in a SGA preterm, immediately treated with a high dose of glucose and glucocorticoid and then with diazoxide. Hypoglycemia was continued until 2 months of age when it resolved spontaneously and completely.

journal_name

Minerva Pediatr

journal_title

Minerva pediatrica

authors

Pezzati M,Barni S,Chiti G,Danesi G,Rubaltelli FF

keywords:

subject

Has Abstract

pub_date

2003-02-01 00:00:00

pages

79-82

issue

1

eissn

0026-4946

issn

1827-1715

journal_volume

55

pub_type

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