Abstract：
:Hydrogen concentration in expired breath depends on the fraction of ingested carbohydrates unabsorbed by the small intestinal mucosa which reach the large intestine and are fermented by the colonic flora. The aim of this study is to assess whether in coeliac children breath hydrogen excretion reflects the histological changes in the jejunal mucosa. Hydrogen breath test was performed on 40 children (15 males 25 females) divided into three groups. Group I (controls): 9 children with symptoms suggestive of coeliac disease who, after the appropriate workup, were found to suffer from other gastrointestinal disorders and had abnormal jejunal mucosa. Group II: 14 children who had been diagnosed as coeliacs according to the ESPGAN criteria, were kept on a gluten free diet for a minimum of 6 months and had a normal jejunal mucosa. Group III: 17 coeliac children who ate small quantities of gluten or were on a normal diet. At histology, 10 of them showed a total and 7 a partial atrophy of the jejunal mucosa. Breath hydrogen levels were measured both at baseline and after ingestion of a 2% sorbitol solution in water, at 30 minute intervals for four hours. The peak hydrogen level and the total surface area under the hydrogen excretion curve were also assessed. Coeliac children on a gluten containing diet excrete significantly more H2 than controls or coeliacs on a gluten free diet. Patients with more severe histological lesions had higher peak H2 levels and greater total excretion areas. In coeliac children, sorbitol breath H2 test represents a simple noninvasive technique to detect impaired jejunal function and it should have an important role as a screening test and in assessing dietary compliance.
journal_name
Minerva Pediatrjournal_title
Minerva pediatricaauthors
Ansaldi-Balocco N,Malorgio E,Faussone D,Dell'Olio D,Morra I,Forni M,Oderda Gsubject
Has Abstractpub_date
1994-12-01 00:00:00pages
569-74issue
12eissn
0026-4946issn
1827-1715journal_volume
46pub_type
临床试验,杂志文章abstract：AIM:Glioneuronal tumors (especially gangliogliomas and dysembryoplastic neuroepithelial tumors) are an increasingly recognised cause of drug-resistant epilepsy in children. The optimal surgical strategy (lesionectomy vs. extended resection of epileptogenic peritumoral areas) to obtain seizure control has not been fully...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2013-12-01 00:00:00
abstract：AIM:The aim of this study was to assess the impact and the peculiarities of cerebral palsy (CP) in children discharged from our neonatal intensive care unit (NICU) from January 1998 to April 2004. METHODS:A total of 2 303 children were discharged from our NICU during this period and 1 912 were followed up for 1 year t...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2006-04-01 00:00:00
abstract：:The study of children with focal brain injury has important implications from a clinical and theoretical perspective. Clinical data on children with congenital or early acquired lesions indicates that the cognitive sequelae are different from those resulting from similar damage sustained in adulthood. These difference...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：1993-06-01 00:00:00
abstract：AIM:Despite the availability of a number of pharmacological options, relief of allergic rhinitis (AR) symptoms, especially nasal obstruction, is often limited and local and systemic adverse reactions are not infrequent. The main aim of the present pilot study was to provide subjective and objective evidence of the clin...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2015-06-01 00:00:00
abstract：BACKGROUND AND AIMS:The hypothesis of an emotional component in asthma has been put forward since antiquity. It is currently explored using a psychodynamic, cognitive-behavioural and systemic-relational approach. This study, carried out using a psychodynamic approach, aimed to identify the psychological aspects of recu...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1998-03-01 00:00:00
abstract：:Varicella or chickenpox is a common and highly contagious exanthematic disease caused by the varicella-zoster virus (VZV) that during primary infection has the ability to establish latency. VZV reactivation, even decades after primary infection, causes herpes zoster. In healthy immunocompetent subjects, children in pa...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2016-06-01 00:00:00
abstract：:Age of diagnosis and clinical pattern were studied in 97 celiac patients, diagnosed with jejunal biopsy, between 1976-1991. They were selected on the basis of clinical and laboratory patterns. The laboratory tests utilized were steatorrhea and xylose in the first years, while in recent years AGA, ARA and AEA were also...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1996-09-01 00:00:00
abstract：BACKGROUND:To evaluate if vesicoureteral reflux (VUR) contralateral to the multicystic dysplastic kidney can interfere with the compensatory renal hypertrophy. METHODS:Twenty-seven patients (17 males, 10 females) with multicystic dysplastic kidney (MDK) (14 on the right, 13 on the left) have been treated at the Nephro...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2001-04-01 00:00:00
abstract：AIM:In the last few years we noted an increasing number of children with celiac disease with negative serum anti-gliadin antibodies (AGA) a useful serologic test to monitor compliance to gluten-free diet. The aim of this study was to verify diagnostic accuracy of AGA and compare clinical characteristics of AGA-negative...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2010-04-01 00:00:00
abstract：:The dominant cause of mortality, morbidity and hospitalization worldwide is cardiac complications, and are the major public health problem in adult populations. The worldwide research is being focused on the idea that cardiovascular disease is an early life pathological state. Early unfavorable exposures, acting in di...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：10.23736/S0026-4946.16.04713-7
更新日期：2017-06-01 00:00:00
abstract：:The sudden infant death syndrome (SIDS) is the sudden dead of every infant or small child (usually within the first year of life). It is an unexpected event, according to the anamnesis of the subject, and the necroscopic examination of the event does not allow to demonstrate with success the proper cause of death. The...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2010-04-01 00:00:00
abstract：BACKGROUND:Recently it is often very frequent a request of specialist consultation for children with psychic discomfort expressed through somatic complaints and/or behavior disorders. The real meaning of these symptoms in terms of prognosis, is not clear; indeed they can be the first signs of a poor prognosis of develo...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1998-09-01 00:00:00
abstract：:Early recognition of shock is the key to successful resuscitation in critically ill children. Often, shock results in or co-exists with myo-cardial dysfunction or acute lung injury. Recognition and appropriate management of these insults is crucial for successful outcomes. Resuscitation should be directed to restorati...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2009-02-01 00:00:00
abstract：:During the first week of life, 400 IU per day of 25(OH)D3 were given to 126 preterm and 112 full-term, small for date newborn infants, while 1000 UI per day of Vitamin D2 were given to 18 preterm and 27 full-term, small for date newborn infants, in order to compare their effectiveness for the prevention of neonatal hy...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1990-05-01 00:00:00
abstract：BACKGROUND:Developmental Dyslexia is a disorder, highly frequent in the school population, for which the recommended rehabilitation procedures are not well defined. This study aimed to automatize reading decoding skills by using an innovative system for rehabilitation, based on a telerehabilitation method. It requires ...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：10.23736/S0026-4946.16.04426-1
更新日期：2018-12-01 00:00:00
abstract：INTRODUCTION:Chronic rhinosinusitis (CRS) is defined as an inflammatory disorder of the paranasal sinuses and of the nasal mucosa that lasts 12 weeks or longer. In CRS microbes contribute to the disease pathogenesis. Clinical microbiology is focused on finding single pathogens that causes the disease and the main goal ...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：10.23736/S0026-4946.20.05850-8
更新日期：2020-07-29 00:00:00
abstract：:Little is known about the overlapping symptoms and comorbidity of pediatric bipolar disorder (BD) and pervasive developmental disorders (PDD) in youth. The aim of this study was to clearly differentiate the symptoms, understand the prevalence and patterns of comorbid presentations, as well as to provide a summary of e...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2008-02-01 00:00:00
abstract：:Congenital dermal sinus represents a dysraphic state of the central nervous system. It can show up throughout a defect of the midline, of both the skull and the spine. Usually, the malformation presents a fistulous tract, connecting the skin with the underlying tissues (hypoderm, paraspinal muscles, vertebrae and, in ...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：1990-12-01 00:00:00
abstract：:Sidenham's chorea represents one of the gold standards of rheumatic fever. Its identification however has recently become more difficult, owing to the progressive decrease of rheumatic fever itself. Nevertheless this pathology disturbing both the child and the family, easily dominated by a suitable therapy, is still t...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1994-04-01 00:00:00
abstract：:Asthma therapy recognizes three fundamental key points: primary prevention, secondary prevention, including the control of inflammatory mechanisms and related symptoms, and tertiary prevention, consisting in the treatment of the early phases leading to airway remodelling. As for primary prevention in infants at ''high...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2008-04-01 00:00:00
abstract：:The development and evaluation of early preventative interventions for individuals exposed to a potentially traumatic event (PTE) have been increasing in number and sophistication over the last decade. Evaluation of early interventions for individuals who are symptomatic several weeks after exposure to a PTE have been...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2011-06-01 00:00:00
abstract：:Subjects suffering from bronchial asthma being treated with theophylline often have to be treated with an antibiotic during acute stages. The purpose of the present study is to assess to clearance variation in theophylline when a macrolide antibiotic is associated after theophyllinemia steady-state has been attained. ...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：1989-06-01 00:00:00
abstract：BACKGROUND:Acute gastroenteritis is responsible for dehydration in many children. The viruses like rotavirus, norovirus, and adenovirus are considered the main causative agents of gastroenteritis. The goal of this study is the evaluation of the symptoms, clinical findings and hospitalization requirements in pediatric p...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：10.23736/S0026-4946.16.04259-X
更新日期：2018-04-01 00:00:00
abstract：:This paper reports a case of pyloric duplication, an extremely rare abnormality usually discovered during infancy. Clinical findings involved mainly symptoms of obstruction and radiological evaluation included abdominal US, plain radiography and CT imaging. Pyloric duplication was diagnosed by US and confirmed by CT s...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2006-08-01 00:00:00
abstract：:Central pontine myelinolysis (CPM) is a demyelinating disease of the pons often associated with the demyelination of extrapontine areas of the central nervous system. It typically occurs 0.5-7 days after a rapid increment in serum Na level in hyponatremic patients and may lead to death. A 2.5-year-old child with a dia...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2011-02-01 00:00:00
abstract：BACKGROUND:The aim of this study is to investigate the use of methylene blue in perioperative identification of the patent processus vaginalis in a group of boys presenting with congenital or recurrent hydrocele where surgery was performed by junior surgeons in training. METHODS:We retrospectively reviewed the notes o...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：10.23736/S0026-4946.17.04661-8
更新日期：2020-04-01 00:00:00
abstract：BACKGROUND:Plasma-exchange (PEX) has been well described in pediatrics, but most of the current indications are derived from adult experience. Aim of the study was to review the PEX treatments in our Unit over a six-year period. METHODS:Three hundred and seventy-seven PEX sessions were performed in 38 patients (median...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：10.23736/S0026-4946.16.04152-9
更新日期：2017-04-01 00:00:00
abstract：:In recent years, infection with cytomegalovirus (CMV) was the subject of numerous studies, one side being the most frequent congenital infection in newborns and one that determines the increased incidence of sequelae distance (about one third of childhood deafness is due to CMV), and the other one of the most frequent...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2013-10-01 00:00:00
abstract：:Providing optimal mechanical ventilation to critically-ill children remains a challenge. Patient-ventilator dyssynchrony results frequently with numerous deleterious consequences on patient outcome including increased requirement for sedation, prolonged duration of ventilation, and greater imposed work of breathing. M...
journal_title：Minerva pediatrica
pub_type： 杂志文章,评审
doi：
更新日期：2016-12-01 00:00:00
abstract：AIM:The prevalence of systemic reactions (SR) to Hymenoptera stings in children was estimated in values lower than 1% in early studies but much higher in recent surveys. We evaluated the current prevalence and the incidence of SR and large local reactions (LLR) to Hymenoptera stings in children in Italy. METHODS:The d...
journal_title：Minerva pediatrica
pub_type： 杂志文章
doi：
更新日期：2014-08-01 00:00:00
