[Congenital cytomegalovirus infection: current status and future perspectives].

Abstract:

:In recent years, infection with cytomegalovirus (CMV) was the subject of numerous studies, one side being the most frequent congenital infection in newborns and one that determines the increased incidence of sequelae distance (about one third of childhood deafness is due to CMV), and the other one of the most frequent and serious opportunistic infections in immunocompromised individuals. Of newborns with congenital infection, approximately 10% are symptomatic at birth. Of the remaining 90%, asymptomatic at birth, 10-15% will develop sequelae from a distance. Regarding the possibility of vertical transmission of the disease from mother to fetus, the debate is still open on the usefulness or not to set a screening during pregnancy in order to prevent or limit the damage caused fetal infection. Despite detailed knowledge about the epidemiology and pathogenesis of CMV disease in pregnant women, this infection remains largely unknown to most women. The opportunity of a serological screening is important, however, since more than 90% of primary CMV infection in pregnancy are asymptomatic and may remain asymptomatic in the fetus. The education on methods to prevent transmission of CMV, particularly among young women of childbearing age, must continue until an effective vaccine becomes available. In this article we summarize the current concepts regarding the epidemiology, pathogenesis, symptoms and prevention of CMV disease, with particular focus on strategies to improve awareness of the risk of CMV infection in women of childbearing age.

journal_name

Minerva Pediatr

journal_title

Minerva pediatrica

authors

Avarello I,Cancemi A,D'Ambra A

subject

Has Abstract

pub_date

2013-10-01 00:00:00

pages

541-63

issue

5

eissn

0026-4946

issn

1827-1715

pii

R15Y2013N05A0541

journal_volume

65

pub_type

杂志文章,评审
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    authors: Tronci A,Catamo R,Corvaglia L,Montinaro R,Ponzi G

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    authors: Pellai A,Vetrano S,Nobile M,Luti C

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    authors: Buonocore G,Bellieni C

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    authors: Deftereos S,Tsalkidis A,Soultanidis H,Limas C,Manavis J

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    doi:

    authors: Pasolini D,Weber G,Rubinacci A,Rinaldi GP,Chiumello G

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  • Serum cytokines in paediatric neuropsychiatric syndromes: focus on Attention Deficit Hyperactivity Disorder.

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    authors: Donfrancesco R,Nativio P,Borrelli E,Giua E,Andriola E,Villa MP,DI Trani M

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  • [RAST positivity for food in atopic dermatitis].

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    authors: Ferrari G,De Amici M,Notarangelo LD,Monafo V,Burgio GR

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  • Unusual Gilbert's syndrome genotype in a Greek patient suffering from both Gilbert's syndrome and familial mediterranean fever. A case report.

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    pub_type: 杂志文章

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    authors: Kalotychou V,Kanta A,Rombos Y,Konstantopoulos K

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    pub_type: 杂志文章

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    pub_type: 杂志文章

    doi:

    authors: Bassoli L,Boncinelli S,Brizzi L,Curci R,Signorelli D,Pazardjiklian I,Pellai A

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    authors: Lucigrai G,Costa A,Dell'Acqua AM,Magnano G,Fondelli MP,Garré ML,Tomà P

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    doi:10.23736/S0026-4946.20.05766-7

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    journal_title:Minerva pediatrica

    pub_type: 杂志文章

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    更新日期:2004-10-01 00:00:00

  • The value of pancreatic stone protein in the prediction of infected neonates.

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  • Clinical features and physiotherapy management for Covid-19 in children.

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    authors: Palagiano A,Pace MC

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  • [Development of percentile curves of arterial pressure of a school population of children aged 6-11 years].

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    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:

    authors: Manganaro R,De Luca F,Lo Sciotto P,Lombardo F,Santisi G,Mamì C

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  • [Calcium-phosphate metabolism and bone markers in two patients with Noonan's syndrome treated with growth hormone].

    abstract:AIM:To evaluate the possible effects of recombinant growth hormone (rhGH) therapy on mineral homeostasis and bone turnover, the authors studied calcium-phosphate metabolism parameters, including some bone markers, in 2 prepubertal subjects with Noonan's syndrome (NS). METHODS:Two prepubertal males suffering from NS, s...

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    authors: Praticò G,Palano GM,Lo Presti D,Parisi G,Caruso-Nicoletti M

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    journal_title:Minerva pediatrica

    pub_type: 杂志文章,评审

    doi:

    authors: Brewer M,Pawelczak M,Kessler M,Shah B

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  • [Respiratory emergencies in adolescents].

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    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:

    authors: Pirlo D,Gastaldi R,Di Pietro P

    更新日期:2002-12-01 00:00:00

  • Intermittent treatment with high dose nebulized beclomethasone for recurrent wheezing in infants due to upper respiratory tract infection.

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    journal_title:Minerva pediatrica

    pub_type: 杂志文章

    doi:

    authors: Ghirga G,Ghirga P,Fagioli S,Colaiacomo M

    更新日期:2002-06-01 00:00:00

  • Prevalence and incidence of reactions to insect stings in children: a reappraisal.

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    pub_type: 杂志文章

    doi:

    authors: Quercia O,Incorvaia C,Marseglia GL,Puccinelli P,Dell'albani I,Emiliani F,Frati F,Stefanini GF

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  • [Treatment of childhood obesity].

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    journal_title:Minerva pediatrica

    pub_type: 指南,杂志文章,实务指引

    doi:

    authors: Trifirò G,Salvatoni A,Tanas R,Brambilla P,Maffeis C,Gruppo di Studio sull'Obesità della SIEDP.

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    pub_type: 杂志文章

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