Abstract：
OBJECTIVES:Following tooth pulp exposure, pulpal repair is accomplished by dentine bridge secretion by odontoblast-like cells. However, little information is available about the hierarchy of variables, which influence odontoblast-like cell numbers. The purpose of this study was to examine correlations between pulp capping events and odontoblast-like cell numbers. METHODS:Two hundred and fifty standardised pulp exposed cavities were prepared in non-human primate teeth according to ISO usage guidelines. Exposed pulps were capped with Calcium hydroxide [Ca(OH)(2)], and multi-step and self-etching primer composite resins. Teeth were collected from 3 to 60-days to observe pulp reactions. Statistical analysis was evaluated using analysis of variance. RESULTS:The hierarchy of variables correlated to odontoblast-like cells were the dentine bridge area (P = 0.0001), time since pulp exposure (P = 0.0001), odontoblast numbers opposite the exposure site (P = 0.0002), and pulp capping materials (P = 0.0313). Other pulp capping variables were found to be less likely to be correlated with odontoblast-like cell numbers. CONCLUSIONS:The area of dentine bridge formation is directly related to the numbers of odontoblast-like cells, cell activity is time dependent, and the cell numbers are much lower than original odontoblast cells. The time-lag between the appearance of odontoblast-like cells at the site of pulp exposure, and the limited numbers of these cells, explain why pulpal repair is difficult to achieve successfully following pulp exposure.
journal_name
J Dentjournal_title
Journal of dentistryauthors
Murray PE,Kitasako Y,Tagami J,Windsor LJ,Smith AJdoi
10.1016/s0300-5712(02)00024-6keywords:
subject
Has Abstractpub_date
2002-09-01 00:00:00pages
297-304issue
7-8eissn
0300-5712issn
1879-176Xpii
S0300571202000246journal_volume
30pub_type
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journal_title：Journal of dentistry
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更新日期：2014-08-01 00:00:00
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更新日期：2020-06-01 00:00:00
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doi：10.1016/0300-5712(95)00051-8
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更新日期：2011-07-01 00:00:00
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更新日期：2018-01-01 00:00:00
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更新日期：2020-12-01 00:00:00
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更新日期：2007-06-01 00:00:00
abstract：OBJECTIVES:This study evaluated the effect of a chromium interlayer deposited by electroplating on the adhesion between titanium and porcelain by means of strain energy release rate (G-value (J/m(2)) or interfacial toughness). METHODS:Seventy rectangular specimens of commercially pure titanium (CP Ti) plates grade II ...
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更新日期：2010-08-01 00:00:00
