Abstract:
OBJECTIVES:The tooth-resin bond is the weak link of restoration, with secondary caries as a main reason for failure. Calcium phosphate-containing resins are promising for remineralization; however, calcium (Ca) and phosphate (P) ion releases last only a couple of months. The objectives of this study were to develop the first rechargeable CaP bonding agent and investigate the key factors that determine CaP ion recharge and re-release. METHODS:Nanoparticles of amorphous calcium phosphate (NACP) were synthesized. Pyromellitic glycerol dimethacrylate (PMGDM), ethoxylated bisphenol-A dimethacrylate (EBPADMA), 2-hydroxyethyl methacrylate (HEMA), and bisphenol-A glycidyl dimethacrylate (BisGMA) were used to synthesize three adhesives (denoted PE, PEH and PEHB). NACP were mixed into adhesive at 0-30% by mass. Dentin shear bond strengths were measured. Adhesive specimens were tested for Ca and P initial ion release. Then the ion-exhausted specimens were immersed in Ca and P solution to recharge the specimens, and the recharged specimens were then used to measure ion re-release for 7 days as one cycle. Then these specimens were again recharged and the re-release was measured for 7 days as the second cycle. Three recharge/re-release cycles were tested. RESULTS:PEHB had the highest dentin bond strength (p<0.05). Increasing NACP content from 0 to 30% did not affect dentin bond strength (p>0.1), but increased CaP release and re-release (p<0.05). PEHB-NACP had the greatest recharge/re-release, and PE-NACP had the least (p<0.05). Ion release remained high and did not decrease with increasing the number of recharge/re-release cycles (p>0.1). After the third cycle, specimens without further recharge had continuous CaP ion release for 2-3 weeks. SIGNIFICANCE:Rechargeable CaP bonding agents were developed for the first time to provide long-term Ca and P ions to promote remineralization and reduce caries. Incorporation of NACP into adhesive had no negative effect on dentin bond strength. Increasing NACP filler level increased the ion recharge and re-release capability. The new CaP recharge method and PMGDM-EBPADMA-NACP composition may have wide application in adhesives, composites and cements, to combat caries and remineralize lesions.
journal_name
J Dentjournal_title
Journal of dentistryauthors
Zhang L,Weir MD,Hack G,Fouad AF,Xu HHdoi
10.1016/j.jdent.2015.06.009subject
Has Abstractpub_date
2015-12-01 00:00:00pages
1587-95issue
12eissn
0300-5712issn
1879-176Xpii
S0300-5712(15)30006-3journal_volume
43pub_type
杂志文章abstract:OBJECTIVE:The primary goal is to develop a self-cured polyacid-modified resin composite with good mechanical and rheological properties. To achieve such a goal, the aim of this study is to determine how volume filler fraction (VFF) affects mechanical properties and viscosities of such materials containing different fil...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/s0300-5712(03)00091-5
更新日期:2003-08-01 00:00:00
abstract:AIM:It is the aim of this paper to investigate the survival of direct-placement restorations provided within the General Dental Services in England and Wales, in relation to the dentist factors which may affect this. METHODS:For this work, survival of a restoration was considered to be the time between the date of com...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2005.03.009
更新日期:2005-11-01 00:00:00
abstract:OBJECTIVES:To review the established and novel methods of plaque quantification employed in dental research, including a discussion of their merits and to present a new method of planimetrically measuring plaque using light induced fluorescence. METHOD:Quantitative light-fluorescence (QLF) images were acquired from th...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2004.10.017
更新日期:2005-03-01 00:00:00
abstract:OBJECTIVES:To evaluate the effect of using a bulk-fill flowable base material on fracture strength and fracture patterns of root-filled maxillary premolars with MOD preparations restored with laminate restorations. METHODS:Fifty extracted maxillary premolars were selected for the study. Standardized MOD cavities with ...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2017.05.016
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to compare the behavior of two new, low-shrinkage hybrid composites (Aelite LS and Inten-S) with a microfilled (Heliomolar) and a hybrid composite (Filtek Z250), in terms of polymerization contraction stress and microleakage. METHODS:Maximum contraction stress after 10 min was recor...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2004.01.014
更新日期:2004-07-01 00:00:00
abstract:OBJECTIVE:To compare the permeability of the occlusal and the cervical dentinal regions within the same tooth, which represent the bottom of Class I and V cavities, respectively, with two different compositions of perfusion fluid, in vitro. METHODS:An occlusal and a buccal disc were cut from each extracted third molar...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/s0300-5712(02)00005-2
更新日期:2002-02-01 00:00:00
abstract:AIM:The main goal of this prospective clinical study was to evaluate the outcome of inlay-retained fixed dental prostheses (FDPs) made from heat-pressed lithium-disilicate glass-ceramic. METHODS:Forty-five FDPs were placed in 42 patients (21 women, mean age 36.1 years and 21 men, mean age 42.0 years). The FDPs replace...
journal_title:Journal of dentistry
pub_type: 临床试验,杂志文章
doi:10.1016/j.jdent.2010.07.012
更新日期:2010-11-01 00:00:00
abstract:OBJECTIVES:To determine the phenotypic and molecular characteristics of Enterococcus faecalis recovered from primary endodontic infections in Brazilian patients. METHODS:Twenty isolates of E. faecalis recovered from 43 Brazilian patients with primary endodontic infections were identified by biochemical profiling (API2...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2013.07.004
更新日期:2013-09-01 00:00:00
abstract:OBJECTIVES:The light intensity of curing lights used in private dental offices was measured using commercial curing and heat radiometers and related to uniformity of cure depth of standardized composite specimens. METHODS:The intensity of 130 curing light from 107 dental offices was measured with curing and heat radio...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/s0300-5712(98)00052-9
更新日期:1999-03-01 00:00:00
abstract::The effects of sample thickness on the in vitro bond strength of two light-activated glass polyalkenoate cements to dentine have been investigated. The buccal and/or lingual surfaces of non-carious human third molar teeth were used for bonding. The tensile bond strengths to dentine of samples of the cements of 0.5 mm,...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/0300-5712(94)90123-6
更新日期:1994-08-01 00:00:00
abstract:OBJECTIVE:This study aims to analyze the addition of niobium silicate particles to dental adhesive resins and evaluate its physicomechanical and biological properties. METHODS:The SiNb particles were produced by the sol-gel route and presented a mean particle size of 2.1 μm and a specific surface area of 616,96m2/g. A...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2020.103449
更新日期:2020-10-01 00:00:00
abstract:OBJECTIVES:To monitor zirconia-ceramic and metal-ceramic posterior FDPs with respect to survival and technical/biological complication rates. MATERIALS AND METHODS:Fifty-eight patients received 76 3- to 5-unit posterior FDPs. The sites were randomly assigned to 40 zirconia-based (ZC) and 36 metal-based (MC) FDPs. FDPs...
journal_title:Journal of dentistry
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jdent.2018.05.015
更新日期:2018-09-01 00:00:00
abstract:AIM:The aim of this study is to report the subsequent treatment provided, over the 11 years' data available, when a re-intervention was considered clinically necessary on a glass ionomer (GI) restoration. METHODS:A detailed sample of treatment records of patients has been established at the Dental Practice Division of...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2008.07.008
更新日期:2009-01-01 00:00:00
abstract::Memory and psychophysiological variables in persons with self-reported reactions to dental amalgam (amalgam patients: N=26) and in persons without such symptoms (controls: N=21) were compared. The groups were matched regarding age, education, and amount of amalgam. Wechsler Memory Scale-Revised was obtained for all su...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/s0300-5712(03)00086-1
更新日期:2003-09-01 00:00:00
abstract:OBJECTIVES:This study aimed to evaluate the effect of low-fluoride toothpastes with calcium glycerophosphate (CaGP) on enamel remineralization in situ. METHODS:Volunteers (n=10) wore palatal devices holding four bovine enamel blocks. The treatments involved 5 experimental phases of 3 days each according to the followi...
journal_title:Journal of dentistry
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jdent.2014.09.001
更新日期:2014-12-01 00:00:00
abstract::Formaldehyde is responsible for allergic inflammation in acrylic denture wearers and the quantitation of formaldehyde is necessary to study its leaching from denture-base materials. Flow injection analysis was developed to quantify the formaldehyde leached from acrylic resins. Different resins were immersed in aqueous...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/0300-5712(93)90136-e
更新日期:1993-08-01 00:00:00
abstract:OBJECTIVES:Sleep bruxism (SB), characterized by repetitive jaw-muscle activity during sleep, is often suggested as a cause of temporomandibular disorders (TMD), orofacial pain, and headache. This study aimed to challenge the relationship between jaw-muscle electromyographic (EMG) activity during sleep and jaw muscle sy...
journal_title:Journal of dentistry
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jdent.2019.01.013
更新日期:2019-03-01 00:00:00
abstract:OBJECTIVE:Several studies have made comparisons in the dimensional accuracy of different elastomeric impression materials. Most have used two-dimensional measuring devices, which neglect to account for the dimensional changes that exist along a three-dimensional surface. PURPOSE:The aim of this study was to compare th...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2004.07.005
更新日期:2004-11-01 00:00:00
abstract:OBJECTIVES:To compare the lifetime of Y-TZP/porcelain crowns under three different load conditions using step-stress accelerated lifetime testing. METHODS:The Y-TZP frameworks were milled using CAD/CAM, veneered with a porcelain and cemented onto dentine analogue dies. Specimens were divided according to the occlusal ...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2015.01.012
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVES:Firstly, to evaluate the in vitro anti-erosion efficacy of a new mouthrinse formulation containing 450 ppm fluoride using profilometry and microindentation. Secondly, to compare fluoride uptake by erosive lesions from two mouthrinses containing different fluoride sources using dynamic secondary ion mass spec...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/S0300-5712(11)70004-5
更新日期:2010-11-01 00:00:00
abstract:INTRODUCTION:Quantification of collagen degradation is an important parameter to evaluate dentin caries progression or the efficacy of caries prevention aid. The aim of this study was to validate the simple light microscopic technique (LM) to evaluate collagen degradation by comparing with hydroxyproline assay techniqu...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2016.01.001
更新日期:2016-04-01 00:00:00
abstract:OBJECTIVES:To determine the influence of two enamel conditioning techniques on buccal and lingual tooth surfaces at two different times on debonding strength and tooth damage. METHODS:The study included 50 premolars. Buccal and lingual surfaces of 10 teeth were scanned using SEM before (N=4) and after enamel condition...
journal_title:Journal of dentistry
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.jdent.2004.08.005
更新日期:2005-02-01 00:00:00
abstract:OBJECTIVES:To evaluate the influence of different surface treatments on the microtensile bond strength of a dual-cured resin composite to fiber posts. METHODS:Thirty-two glass methacrylate-based fiber posts (GC Corp.) were used in the study. Posts were divided into two groups, according to the surface pretreatment per...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2007.01.009
更新日期:2007-06-01 00:00:00
abstract:OBJECTIVES:This randomized, parallel group, single centre clinical trial was conducted to evaluate the safety and compare the whitening efficacy for an extended wear of an experimental 9.5% H₂O₂ high-adhesion whitening strip, relative to a marketed 10% H₂O₂ control strip. METHODS:Twenty-nine eligible adult volunteers ...
journal_title:Journal of dentistry
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jdent.2012.11.019
更新日期:2013-08-01 00:00:00
abstract:OBJECTIVES:The aim of the present study was to review the current literature relating to the impact of dental implants on oral health-related quality of life (OHRQoL) in edentulous or partially dentate patients. DATA/SOURCES:Systematic literature searches were performed in the PubMed, EMBASE, and Cochrane Library data...
journal_title:Journal of dentistry
pub_type: 杂志文章,评审
doi:10.1016/j.jdent.2017.08.003
更新日期:2017-10-01 00:00:00
abstract:OBJECTIVE:Sodium hexametaphosphate (SHMP) is a widely used industrial preservative commonly found in children's drinks. In this paper we examined the effect of SHMP incorporated into children's drinks on acid production by the oral biofilm by monitoring salivary concentrations of lactic acid. MATERIALS AND METHOD:Twel...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2006.08.003
更新日期:2007-03-01 00:00:00
abstract:OBJECTIVES:A low pH environment is created by cariogenic bacteria. This study was aimed to measure pH of carious lesions intraorally using a micro-pH sensor, and assess predominant acid-producing cariogens by qPCR to differentiate caries activities. METHODS:103 dentine lesions classified as active or arrested caries b...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2011.12.013
更新日期:2012-03-01 00:00:00
abstract:OBJECTIVES:To compare the accuracies of 4 laboratory scanners using a new custom-made block for complete-arch implant rehabilitation. MATERIALS AND METHODS:A block comprised 4 cylinders, with 2 in the anterior (0° angulation) and 2 in the posterior region (45° distal angulation) (Experimental group) and a standard blo...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2020.103476
更新日期:2020-11-01 00:00:00
abstract:OBJECTIVES:The aim of the current study was to evaluate the effect of 2% CHX and 2% CHX-methacrylate compared to the resin-dentin bonds created by a two-step etch-and-rinse adhesive system after 24h, 6min and 12min. METHODS:Microtensile bond strengths and interfacial nanoleakage within resin-dentin interfaces created ...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2015.11.002
更新日期:2016-02-01 00:00:00
abstract:OBJECTIVES:Demineralized lesions in tooth enamel around orthodontic brackets are caused by acids from cariogenic biofilm. This study aimed to develop a novel antibacterial orthodontic cement by incorporating a quaternary ammonium monomer dimethylaminododecyl methacrylate (DMADDM) into a commercial orthodontic cement, a...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2014.07.006
更新日期:2014-09-01 00:00:00