Comparison of the in vitro permeability of human dentine according to the dentinal region and the composition of the simulated dentinal fluid.

Abstract:

OBJECTIVE:To compare the permeability of the occlusal and the cervical dentinal regions within the same tooth, which represent the bottom of Class I and V cavities, respectively, with two different compositions of perfusion fluid, in vitro. METHODS:An occlusal and a buccal disc were cut from each extracted third molar at a level close to the pulp chamber. The convective permeability of the discs was measured in a fluid transport model using de-ionised water or 1:3 diluted bovine serum and the hydraulic conductance was determined. RESULTS:The mean hydraulic conductance values of the occlusal and the buccal cervical human dentine to water were 0.069 and 0.047 microl min(-1) cm(-2) cm H(2)O(-1), respectively. When diluted bovine serum was used, the corresponding values were 0.036 and 0.012 microl min(-1) cm(-2) cm H(2)O(-1), respectively. Statistical analysis revealed no significant difference between the permeability of these two regions. The composition of the perfusion fluid significantly influenced the permeability of dentine. CONCLUSIONS:The occlusal and the buccal cervical regions of human dentine have similar permeability characteristics in vitro. There is a strong reverse correlation between the viscosity of the perfusion fluid and the perfusion through the dentine.

journal_name

J Dent

journal_title

Journal of dentistry

authors

Ozok AR,Wu MK,Wesselink PR

doi

10.1016/s0300-5712(02)00005-2

keywords:

subject

Has Abstract

pub_date

2002-02-01 00:00:00

pages

107-11

issue

2-3

eissn

0300-5712

issn

1879-176X

pii

S0300571202000052

journal_volume

30

pub_type

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